| 2022 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity; hydrolase activity; ferric iron binding (ortholog); INVOLVED IN bone resorption; cellular response to zinc ion starvation; multicellular organismal response to stress; PARTICIPATES IN rheumatoid arthritis pathway; riboflavin metabolic pathwa y; ASSOCIATED WITH Alveolar Bone Loss; Experimental Diabetes Mellitus; Postmenopausal Osteoporosis; FOUND IN extracellular space; lysosome (ortholog); INTERACTS WITH (20S)-ginsenoside Rg3; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate | 8 | 28939984 | 28946639 | Rat | 297 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10072 | Acp5 | acid phosphatase 5, tartrate resistant | Enables acid phosphatase activity. Acts upstream of or within several processes, including bone resorption; negative regulation of metabolic process; and response to bacterium. Located in lysosome. Is expressed in several structures, including alimentary system; limb; liver; skeleton; and skin. Huma n ortholog(s) of this gene implicated in spondylometaphyseal dysplasia. Orthologous to human ACP5 (acid phosphatase 5, tartrate resistant). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 22038023 | 22047042 | Mouse | 329 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 10073 | ACP5 | acid phosphatase 5, tartrate resistant | This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008] | 19 | 11574660 | 11578975 | Human | 463 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8883340 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); ferric iron binding (ortholog); ferrous iron binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortho log); Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); lysosome (ortholog) | NW_004955495 | 2418113 | 2421181 | Chinchilla | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11887190 | ACP5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); hydrolase activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortholog); Combined Immunodeficiency wi th Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog) | 19 | 11120451 | 11125167 | Bonobo | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12416750 | ACP5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); hydrolase activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortholog); Combined Immunodeficiency wi th Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); lysosome (ortholog); INTERACTS WITH resveratrol | 20 | 49812444 | 49816262 | Dog | 56 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12557961 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); hydrolase activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortholog); Combined Immunodeficiency wi th Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog) | NW_004936659 | 1598252 | 1642615 | Squirrel | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18774905 | ACP5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); hydrolase activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortholog); Combined Immunodeficiency wi th Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog) | | | | Green Monkey | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13868750 | ACP5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); ferric iron binding (ortholog); ferrous iron binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortho log); Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); lysosome (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 57 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18934838 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); ferric iron binding (ortholog); ferrous iron binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortho log); Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); lysosome (ortholog) | | | | Naked Mole-Rat | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249506 | acp5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626002552 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity (ortholog); ferric iron binding (ortholog); ferrous iron binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); bone resorption (ortholog); cellular response to zinc ion starvation (ortholog); ASSOCIATED WITH Alveolar Bone Loss (ortho log); Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia (ortholog); Desbuquois dysplasia (ortholog); FOUND IN extracellular space (ortholog); lysosome (ortholog) | | | | Black Rat | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155236354 | acp5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155251682 | acp5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14132592 | LOC100738609 | tartrate-resistant acid phosphatase type 5 | | | | | Pig | | old_gene_symbol | gene, protein-coding |
| 621239 | Mt-atp6 | mitochondrially encoded ATP synthase membrane subunit 6 | ENCODES a protein that exhibits proton channel activity (ortholog); proton-transporting ATP synthase activity, rotational mechanism (ortholog); INVOLVED IN response to hyperoxia; proton motive force-driven ATP synthesis (ortholog); proton motive force-driven mitochondrial ATP synthesis (ortholog); P ARTICIPATES IN electron transport chain pathway; ASSOCIATED WITH Reperfusion Injury; adult-onset ataxia and polyneuropathy (ortholog); Ataxia (ortholog); FOUND IN mitochondrion (ortholog); proton-transporting ATP synthase complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | MT | 7919 | 8599 | Rat | 192 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621872 | Mt-co2 | mitochondrially encoded cytochrome c oxidase II | ENCODES a protein that exhibits cytochrome-c oxidase activity (ortholog); INVOLVED IN lactation; response to ethanol; response to hypoxia; ASSOCIATED WITH acute myocardial infarction; Binge Drinking; Brain Injuries; FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | MT | 7006 | 7689 | Rat | 230 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621873 | Mt-co3 | mitochondrially encoded cytochrome c oxidase III | ENCODES a protein that exhibits cytochrome-c oxidase activity (inferred); electron transfer activity (inferred); INVOLVED IN respiratory chain complex IV assembly (ortholog); ASSOCIATED WITH cerebellar ataxia (ortholog); cytochrome-c oxidase deficiency disease (ortholog); epilepsy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1 | MT | 8599 | 9382 | Rat | 145 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620081 | Mt-cyb | mitochondrially encoded cytochrome b | ENCODES a protein that exhibits protein-containing complex binding; quinol-cytochrome-c reductase activity (ortholog); INVOLVED IN animal organ regeneration; electron transport coupled proton transport; response to cadmium ion; ASSOCIATED WITH Burns; Experimental Diabetes Mellitus; Experimental Live r Cirrhosis; FOUND IN mitochondrial inner membrane; protein-containing complex; mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | MT | 14136 | 15278 | Rat | 194 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620555 | Mt-nd1 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to hydroperoxide; response to hypoxia; response to xenobiotic stimulus; ASSOCIATED WITH Hypoxia; type 2 diabetes mellitus; Alzheimer's disease (ortholog); FOUND IN dendrite; neuronal cell body; mitochondrial inner membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamiprid | MT | 2740 | 3694 | Rat | 224 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620556 | Mt-nd2 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; protein kinase binding; NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to hypoxia; mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (or tholog); ASSOCIATED WITH Hypoxia; epilepsy (ortholog); Leber hereditary optic neuropathy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamiprid | MT | 3904 | 4942 | Rat | 134 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620557 | Mt-nd3 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN cellular response to glucocorticoid stimulus; response to hormone; response to light intensity; ASSOCIATED WITH Huntington's disease; hypothyroidism; Parkinson's disease; FOUND IN mitochondrial inner mem brane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; atrazine | MT | 9451 | 9798 | Rat | 117 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620559 | Mt-nd4 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN cerebellum development; in utero embryonic development; response to ethanol; ASSOCIATED WITH Alzheimer's disease (ortholog); Developmental Disabilities (ortholog); dilated cardiomyopathy (ortholog); FOUN D IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | MT | 10160 | 11537 | Rat | 151 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620494 | Mt-nd4l | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN ATP synthesis coupled electron transport (inferred); proton transmembrane transport (inferred); respiratory electron transport chain (inferred); ASSOCIATED WITH colorectal cancer (ortholog); diabetes mel litus (ortholog); dilated cardiomyopathy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | MT | 9870 | 10166 | Rat | 97 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620560 | Mt-nd5 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to hydrogen peroxide; response to hypoxia; mitochondrial electron transport, NADH to ubiquinone (ortholog); ASSOCIATED WITH hepatocellular carcinoma; Hearing Loss (ortholog); Leber congenital am aurosis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | MT | 11736 | 13565 | Rat | 161 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620561 | Mt-nd6 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to cocaine; response to hydrogen peroxide; response to nicotine; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; acute megakaryocytic leukemia (ortholog); autism spectrum disorder (ortho log); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | MT | 13543 | 14061 | Rat | 164 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |