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Strain Registration

Strain: NP.P-(D4Rat119-D4Rat55)/Iusm

Symbol: NP.P-(D4Rat119-D4Rat55)/Iusm
Strain: NP.P-(D4Rat119-D4Rat55)
Substrain: Iusm
RGD ID: 1641877
Citation ID: RRID:RGD_1641877
Ontology ID: RS:0001376
Alleles: Akr1b1;   Npy;   Snca;   Grid2;   Baiap1;   Zfp212;   Ppm1k;   Sos1;   Dgki
Previously known as: C2; NP.P-(D4Rat119-D4Rat55); NP.P-(D4Rat119-D4Rat55)/Iusm; NP.P-(D4Mgh16-D4Rat55); NP.P; iNP.iP
Type: congenic
Source: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
Origin: Male iP and female iNP rats were crossed to get F1 animals which were further backcrossed to iNP rats for 10 generations, this was followed by intercross to generate the congenic strains, these animals were selected by marker-assisted selection
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24126,192,368 - 126,192,555RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0462,947,687 - 125,671,711RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04190,188,458 - 190,188,644RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4462,832,008 - 127,941,994RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Identification of genes influencing skeletal phenotypes in congenic P/NP rats. Alam I, etal., J Bone Miner Res. 2010 Jan 8.
2. Identification of Candidate Genes for Alcohol Preference by Expression Profiling of Congenic Rat Strains. Carr LG, etal., Alcohol Clin Exp Res. 2007 Apr 19;.
3. Development of Congenic Rat Strains for Alcohol Consumption Derived from the Alcohol-Preferring and Nonpreferring Rats. Carr LG, etal., Behav Genet. 2006 Feb 10;:1-6.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D4Rat119)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0462,947,687 - 62,947,927NCBI
RGSC_v3.4462,832,009 - 62,832,241UniSTS
RGSC_v3.4462,832,008 - 62,832,241RGD
RGSC_v3.1463,108,139 - 63,108,371RGD
Celera459,141,073 - 59,141,305UniSTS
RH 3.4 Map4371.7UniSTS
RH 3.4 Map4371.7RGD
SHRSP x BN Map432.92UniSTS
SHRSP x BN Map432.92RGD

Flank 2 / 1 (D4Rat55)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24126,192,368 - 126,192,555 (+)MAPPER
Rnor_6.04125,671,525 - 125,671,711NCBI
Rnor_5.04190,188,458 - 190,188,644UniSTS
RGSC_v3.44127,941,807 - 127,941,994RGD
RGSC_v3.44127,941,808 - 127,941,994UniSTS
RGSC_v3.14128,186,649 - 128,186,835RGD
Celera4115,103,999 - 115,104,185UniSTS
RH 3.4 Map4744.2RGD
RH 3.4 Map4744.2UniSTS
RH 2.0 Map4840.3RGD
SHRSP x BN Map455.5RGD
Cytogenetic Map4q34UniSTS
Strain QTL Data
Symbol Name Trait
Alc22 Alcohol consumption QTL 22 drinking behavior trait   (VT:0001422)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics These are homozygous for the P allele which is responsible for increased alcohol consumption 1578304
strain_other Microarray profiling of gene expression of 5 brain regions confirmed 19 genes and detected an additional 15 genes in this region 1624272