Prmt3 (protein arginine methyltransferase 3) - Rat Genome Database

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Gene: Prmt3 (protein arginine methyltransferase 3) Rattus norvegicus
Analyze
Symbol: Prmt3
Name: protein arginine methyltransferase 3
RGD ID: 620413
Description: Enables modified amino acid binding activity and protein-arginine omega-N asymmetric methyltransferase activity. Involved in dendritic spine morphogenesis and peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. Predicted to be located in cytosol. Predicted to be active in nucleus. Biomarker of asthma. Orthologous to human PRMT3 (protein arginine methyltransferase 3); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; homocysteine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: heterogeneous nuclear ribonucleoprotein methyltransferase-like 3; heterogeneous nuclear ribonucleoprotein methyltransferase-like 3 (S. cerevisiae); heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; Hrmt1l3; protein arginine N-methyltransferase 3; protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81108,628,899 - 108,718,803 (+)NCBIGRCr8
mRatBN7.2199,492,712 - 99,581,774 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,492,724 - 99,579,435 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,846,834 - 104,933,517 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01113,318,757 - 113,405,436 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,641,014 - 106,727,679 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01105,113,595 - 105,200,253 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1105,113,595 - 105,200,470 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01106,163,799 - 106,250,502 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,581,943 - 99,668,604 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,660,053 - 99,746,714 (+)NCBI
Celera193,691,794 - 93,778,258 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prmt3Ratasthma  IEP 9491823mRNA:increased expression:lungRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prmt3Ratintellectual disability  ISOPRMT3 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prmt3Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PRMT3 mRNA]CTDPMID:31150632
Prmt3Rat(-)-epigallocatechin 3-gallate multiple interactionsISOPRMT3 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PRMT3 mRNACTDPMID:22079256
Prmt3Rat(1->4)-beta-D-glucan multiple interactionsISOPrmt3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRMT3 mRNACTDPMID:36331819
Prmt3Rat1,2-dimethylhydrazine affects expressionISOPrmt3 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of PRMT3 mRNACTDPMID:22206623
Prmt3Rat1-nitropyrene increases expressionISOPRMT3 (Homo sapiens)64804641-nitropyrene results in increased expression of PRMT3 mRNACTDPMID:19041380
Prmt3Rat17beta-estradiol increases expressionISOPRMT3 (Homo sapiens)6480464Estradiol results in increased expression of PRMT3 mRNACTDPMID:31614463
Prmt3Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOPrmt3 (Mus musculus)64804642 more ...CTDPMID:30294300
Prmt3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPRMT3 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of PRMT3 mRNACTDPMID:22574217
Prmt3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PRMT3 mRNACTDPMID:33387578
Prmt3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPrmt3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of PRMT3 mRNACTDPMID:19465110 and PMID:19770486
Prmt3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPrmt3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PRMT3 mRNACTDPMID:21570461
Prmt3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of PRMT3 mRNACTDPMID:21346803
Prmt3Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of PRMT3 mRNACTDPMID:21346803
Prmt3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOPRMT3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRMT3 mRNACTDPMID:28628672
Prmt3Rat4,4'-sulfonyldiphenol increases expressionISOPrmt3 (Mus musculus)6480464bisphenol S results in increased expression of PRMT3 mRNACTDPMID:39298647
Prmt3Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of PRMT3 mRNACTDPMID:28959563
Prmt3Ratacrylamide increases expressionISOPRMT3 (Homo sapiens)6480464Acrylamide results in increased expression of PRMT3 mRNACTDPMID:32763439
Prmt3Ratall-trans-retinoic acid decreases expressionISOPRMT3 (Homo sapiens)6480464Tretinoin results in decreased expression of PRMT3 mRNACTDPMID:33167477
Prmt3Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of PRMT3 mRNACTDPMID:16483693
Prmt3Rataristolochic acid A decreases expressionISOPRMT3 (Homo sapiens)6480464aristolochic acid I results in decreased expression of PRMT3 mRNACTDPMID:33212167

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Biological Process
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Cellular Component

  
Object Symbol
Species
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With
Reference
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Source
Original Reference(s)
Prmt3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Prmt3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Prmt3Ratcytoplasm located_inISOPRMT3 (Homo sapiens)1624291 PMID:33495566RGDPMID:33495566
Prmt3Ratcytosol located_inISOPrmt3 (Mus musculus)1624291 PMID:15473865RGDPMID:15473865
Prmt3Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Prmt3Ratnucleus located_inISOPRMT3 (Homo sapiens)1624291 PMID:39513743RGDPMID:39513743
Prmt3Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Prmt3Ratnucleus is_active_inIBAFB:FBgn0032329 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prmt3Rathistone H4R3 methyltransferase activity enablesISOPRMT3 (Homo sapiens)1624291 PMID:39513743RGDPMID:39513743
Prmt3Rathistone methyltransferase activity enablesIBAFB:FBgn0032329 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prmt3Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Prmt3Ratmethyltransferase activity enablesISOPRMT3 (Homo sapiens)1624291 PMID:18573314RGDPMID:18573314
Prmt3Ratmethyltransferase activity enablesIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Prmt3Ratmethyltransferase activity enablesIEAARBA:ARBA000283021600115GO_REF:0000117UniProtGO_REF:0000117
Prmt3Ratmodified amino acid binding  IDA 7243104S-Adenosyl-L-homocysteineRGD 
Prmt3Ratprotein binding enablesISOPRMT3 (Homo sapiens)1624291UniProtKB:P00352 more ...RGDPMID:18573314 more ...
Prmt3Ratprotein-arginine N-methyltransferase activity  IDA 729523 RGD 
Prmt3Ratprotein-arginine N-methyltransferase activity enablesISOPrmt3 (Mus musculus)1624291 PMID:18495660RGDPMID:18495660
Prmt3Ratprotein-arginine N-methyltransferase activity enablesIBACGD:CAL0000187520 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prmt3Ratprotein-arginine N-methyltransferase activity enablesIEAInterPro:IPR0257991600115GO_REF:0000002InterProGO_REF:0000002
Prmt3Ratprotein-arginine N-methyltransferase activity  IDA 7243104 RGD 
Prmt3Ratprotein-arginine omega-N asymmetric methyltransferase activity  IDA 729523 RGD 
Prmt3Ratprotein-arginine omega-N asymmetric methyltransferase activity enablesIEARHEA:480961600115GO_REF:0000116RHEAGO_REF:0000116
Prmt3Ratprotein-arginine omega-N asymmetric methyltransferase activity enablesISOPrmt3 (Mus musculus)1624291 PMID:15473865RGDPMID:15473865
Prmt3Ratprotein-arginine omega-N monomethyltransferase activity enablesIEARHEA:481001600115GO_REF:0000116RHEAGO_REF:0000116
Prmt3RatS-adenosylmethionine-dependent methyltransferase activity  TAS 729523 RGD 
Prmt3Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Prmt3Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
1 to 20 of 20 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prmt3Rathomocysteine metabolic pathway   ISS 1359044 RGD 
Prmt3Ratmethionine cycle/metabolic pathway   ISS 1359044 RGD 
Prmt3Ratmethionine cycle/metabolic pathway   ISOPRMT3 (Homo sapiens)7242552 RGD 

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prmt3Rathistidine metabolic pathway  ISOPRMT3 (Homo sapiens)10402751 SMPDBSMP:00044
Prmt3Rathistidinemia pathway  ISOPRMT3 (Homo sapiens)10402751 SMPDBSMP:00191

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#
Reference Title
Reference Citation
1. Arginine methylation an emerging regulator of protein function. Bedford MT and Richard S, Mol Cell 2005 Apr 29;18(3):263-72.
2. Histone arginine methylation. Di Lorenzo A and Bedford MT, FEBS Lett. 2011 Jul 7;585(13):2024-31. doi: 10.1016/j.febslet.2010.11.010. Epub 2010 Nov 11.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. PRMT3 is essential for dendritic spine maturation in rat hippocampal neurons. Miyata S, etal., Brain Res. 2010 Sep 17;1352:11-20. doi: 10.1016/j.brainres.2010.07.033. Epub 2010 Jul 18.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. [Expression of protein arginine N-methyltransferases in E3 rat models of acute asthma]. Sun QZ, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2010 Apr;30(4):716-9.
10. PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation. Tang J, etal., J Biol Chem 1998 Jul 3;273(27):16935-45.
11. Crystal structure of the conserved core of protein arginine methyltransferase PRMT3. Zhang X, etal., EMBO J. 2000 Jul 17;19(14):3509-19.
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PMID:10931850   PMID:15473865   PMID:18495660   PMID:18573314   PMID:24815167  



Prmt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81108,628,899 - 108,718,803 (+)NCBIGRCr8
mRatBN7.2199,492,712 - 99,581,774 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,492,724 - 99,579,435 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,846,834 - 104,933,517 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01113,318,757 - 113,405,436 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,641,014 - 106,727,679 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01105,113,595 - 105,200,253 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1105,113,595 - 105,200,470 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01106,163,799 - 106,250,502 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,581,943 - 99,668,604 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,660,053 - 99,746,714 (+)NCBI
Celera193,691,794 - 93,778,258 (+)NCBICelera
Cytogenetic Map1q22NCBI
PRMT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381120,387,716 - 20,509,338 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1120,387,558 - 20,509,338 (+)EnsemblGRCh38hg38GRCh38
GRCh371120,409,262 - 20,530,884 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,365,679 - 20,487,349 (+)NCBINCBI36Build 36hg18NCBI36
Celera1120,541,661 - 20,662,994 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1120,092,368 - 20,214,172 (+)NCBIHuRef
CHM1_11120,408,983 - 20,530,723 (+)NCBICHM1_1
T2T-CHM13v2.01120,508,397 - 20,629,944 (+)NCBIT2T-CHM13v2.0
Prmt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39749,428,067 - 49,508,016 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl749,428,094 - 49,508,013 (+)EnsemblGRCm39 Ensembl
GRCm38749,778,319 - 49,861,264 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl749,778,346 - 49,858,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv37757,033,728 - 57,113,635 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36749,646,379 - 49,726,286 (+)NCBIMGSCv36mm8
Celera745,228,154 - 45,308,430 (+)NCBICelera
Cytogenetic Map7B4NCBI
cM Map731.44NCBI
Prmt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554761,223,076 - 1,331,582 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554761,222,579 - 1,331,582 (+)NCBIChiLan1.0ChiLan1.0
PRMT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2922,688,983 - 22,817,065 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11122,648,763 - 22,776,831 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01120,412,419 - 20,538,295 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11120,324,196 - 20,449,681 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1120,324,196 - 20,449,681 (+)Ensemblpanpan1.1panPan2
PRMT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12142,406,327 - 42,530,157 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2142,406,314 - 42,528,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2141,882,566 - 42,006,278 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02143,527,769 - 43,650,988 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2143,527,763 - 43,653,579 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12142,529,594 - 42,653,065 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02142,705,438 - 42,829,263 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02143,087,080 - 43,211,034 (+)NCBIUU_Cfam_GSD_1.0
Prmt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494742,462,572 - 42,589,987 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366541,336,429 - 1,461,476 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366541,336,546 - 1,464,959 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRMT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl238,884,362 - 39,032,996 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1238,884,311 - 39,032,944 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2241,911,569 - 41,930,041 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRMT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,486,165 - 44,621,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,485,880 - 44,620,936 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038141,822,116 - 141,955,377 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prmt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,670,108 - 11,795,272 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,669,732 - 11,797,133 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Prmt3
346 total Variants

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:146
Interacting mature miRNAs:173
Transcripts:ENSRNOT00000020853
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 46 rows
RH141582  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,579,143 - 99,579,339 (+)MAPPERmRatBN7.2
Rnor_6.01105,199,960 - 105,200,155NCBIRnor6.0
Rnor_5.01106,250,209 - 106,250,404UniSTSRnor5.0
RGSC_v3.4199,668,311 - 99,668,506UniSTSRGSC3.4
Celera193,777,965 - 93,778,160UniSTS
RH 3.4 Map1920.5UniSTS
Cytogenetic Map1q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000020853   ⟹   ENSRNOP00000020853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,492,724 - 99,579,435 (+)Ensembl
Rnor_6.0 Ensembl1105,113,595 - 105,200,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079655   ⟹   ENSRNOP00000069745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,492,724 - 99,579,435 (+)Ensembl
Rnor_6.0 Ensembl1105,113,658 - 105,200,470 (+)Ensembl
RefSeq Acc Id: NM_053557   ⟹   NP_446009
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81108,628,924 - 108,718,803 (+)NCBI
mRatBN7.2199,492,768 - 99,579,437 (+)NCBI
Rnor_6.01105,113,595 - 105,200,253 (+)NCBI
Rnor_5.01106,163,799 - 106,250,502 (+)NCBI
RGSC_v3.4199,581,943 - 99,668,604 (+)RGD
Celera193,691,794 - 93,778,258 (+)RGD
Sequence:
RefSeq Acc Id: XM_039093128   ⟹   XP_038949056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81108,628,899 - 108,717,950 (+)NCBI
mRatBN7.2199,492,712 - 99,581,774 (+)NCBI
Protein RefSeqs NP_446009 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949056 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC40158 (Get FASTA)   NCBI Sequence Viewer  
  EDM07219 (Get FASTA)   NCBI Sequence Viewer  
  EDM07220 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020853
  ENSRNOP00000069745
GenBank Protein O70467 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446009   ⟸   NM_053557
- UniProtKB: O70467 (UniProtKB/Swiss-Prot),   A6JBG4 (UniProtKB/TrEMBL),   A0A8L2QAU2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069745   ⟸   ENSRNOT00000079655
Ensembl Acc Id: ENSRNOP00000020853   ⟸   ENSRNOT00000020853
RefSeq Acc Id: XP_038949056   ⟸   XM_039093128
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JW52 (UniProtKB/TrEMBL),   A0A8L2QAU2 (UniProtKB/TrEMBL)
Name Modeler Protein Id AA Range Protein Structure
AF-O70467-F1-model_v2 AlphaFold O70467 1-528 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690078
Promoter ID:EPDNEW_R602
Type:multiple initiation site
Name:Prmt3_1
Description:protein arginine methyltransferase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01105,113,568 - 105,113,628EPDNEW


1 to 30 of 30 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59559 BioCyc
Ensembl Genes ENSRNOG00000014829 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000020853 ENTREZGENE
  ENSRNOT00000079655 ENTREZGENE
Gene3D-CATH 3.40.50.150 UniProtKB/Swiss-Prot
  Hnrnp arginine n-methyltransferase1 UniProtKB/Swiss-Prot
InterPro ANM3-like_C2H2_Zf UniProtKB/Swiss-Prot
  ANM3_Znf-C2H2 UniProtKB/Swiss-Prot
  Arg_MeTrfase UniProtKB/Swiss-Prot
  PRMT_dom UniProtKB/Swiss-Prot
  SAM-dependent_MTases UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
KEGG Report rno:89820 UniProtKB/Swiss-Prot
NCBI Gene 89820 ENTREZGENE
PANTHER PROTEIN ARGININE N-METHYLTRANSFERASE 3 UniProtKB/Swiss-Prot
  PTHR11006 UniProtKB/Swiss-Prot
Pfam ANM3_C2H2_Zf UniProtKB/Swiss-Prot
  ANM3_zf-C2H2 UniProtKB/Swiss-Prot
  PrmA UniProtKB/Swiss-Prot
  PRMT_C UniProtKB/Swiss-Prot
PhenoGen Prmt3 PhenoGen
PROSITE SAM_MT_PRMT UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014829 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot
UniProt A0A0G2JW52 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QAU2 ENTREZGENE, UniProtKB/TrEMBL
  A6JBG4 ENTREZGENE, UniProtKB/TrEMBL
  ANM3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 30 of 30 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-24 Prmt3  protein arginine methyltransferase 3  Prmt3  protein arginine N-methyltransferase 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Prmt3  protein arginine N-methyltransferase 3  Hrmt1l3  heterogeneous nuclear ribonucleoprotein methyltransferase-like 3 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Hrmt1l3  heterogeneous nuclear ribonucleoprotein methyltransferase-like 3 (S. cerevisiae)  Prmt3  protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3  Symbol and Name updated 1299863 APPROVED
2002-08-07 Prmt3  protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_other probably acts as a monomer 729523