Nbl1 (NBL1, DAN family BMP antagonist) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Nbl1 (NBL1, DAN family BMP antagonist) Rattus norvegicus
Analyze
Symbol: Nbl1
Name: NBL1, DAN family BMP antagonist
RGD ID: 3151
Description: Predicted to enable BMP binding activity; identical protein binding activity; and morphogen activity. Predicted to be involved in several processes, including determination of dorsal identity; negative regulation of BMP signaling pathway; and negative regulation of monocyte chemotaxis. Predicted to act upstream of or within neuron projection morphogenesis and positive regulation of neuron differentiation. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Orthologous to several human genes including NBL1 (NBL1, DAN family BMP antagonist); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: N03; neuroblastoma 1; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma suppression of tumorigenicity 1; Neuroblastoma suppression of tumorigenicity 1 (DNA segment human D1S1733E); neuroblastoma suppressor of tumorigenicity 1; neuroblastoma, suppression of tumorigenicity 1; Neuroblastoma, suppression of tumorigenicity 1 (DNA segment human D1S1733E); zinc finger protein DAN
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,601,986 - 156,613,182 (-)NCBIGRCr8
mRatBN7.25151,318,752 - 151,329,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,318,754 - 151,338,719 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5154,015,980 - 154,027,177 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,790,290 - 155,801,487 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,772,293 - 155,783,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,524,569 - 157,535,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,524,513 - 157,535,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,263,765 - 161,274,897 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5149,703,598 - 149,714,771 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nbl1Rat3-hydroxy-3-methylglutaryl-CoA lyase deficiency  ISONBL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of hydroxymethylglutaryl-CoA lyaseClinVarPMID:28492532
Nbl1Ratchromosome 1p36 deletion syndrome  ISONBL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 1p36 deletion syndromeClinVar 
Nbl1Ratcongenital disorder of glycosylation Ir  ISONBL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation type IrClinVarPMID:28492532
Nbl1Rathyperprolinemia type 2  ISONBL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hyperprolinemia type 2ClinVarPMID:28492532
Nbl1RatParkinson's disease 6  ISONBL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive early-onset Parkinson disease 6ClinVarPMID:28492532

1 to 20 of 110 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nbl1Rat14-Deoxy-11,12-didehydroandrographolide decreases expressionISONBL1 (Homo sapiens)648046414-deoxy-11 and 12-didehydroandrographolide results in decreased expression of NBL1 mRNACTDPMID:22101062
Nbl1Rat17beta-estradiol increases expressionISONbl1 (Mus musculus)6480464Estradiol results in increased expression of NBL1 mRNACTDPMID:19484750
Nbl1Rat17beta-hydroxy-5alpha-androstan-3-one increases expressionISONBL1 (Homo sapiens)6480464Dihydrotestosterone results in increased expression of NBL1 mRNACTDPMID:29581250
Nbl1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONBL1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of NBL1 mRNACTDPMID:20106945 and PMID:21632981
Nbl1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of NBL1 mRNACTDPMID:34747641
Nbl1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONbl1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NBL1 mRNACTDPMID:26377647
Nbl1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONbl1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of NBL1 mRNACTDPMID:19933214
Nbl1Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISONbl1 (Mus musculus)64804642 more ...CTDPMID:38648751
Nbl1Rat2-methylcholine affects expressionISONBL1 (Homo sapiens)6480464beta-methylcholine affects the expression of NBL1 mRNACTDPMID:21179406
Nbl1Rat4,4'-sulfonyldiphenol increases expressionISONbl1 (Mus musculus)6480464bisphenol S results in increased expression of NBL1 mRNACTDPMID:30951980
Nbl1Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NBL1 mRNACTDPMID:36041667
Nbl1Rat4,4'-sulfonyldiphenol increases methylationISONbl1 (Mus musculus)6480464bisphenol S results in increased methylation of NBL1 promoterCTDPMID:33297965
Nbl1Rat4-hydroxyphenyl retinamide decreases expressionISONbl1 (Mus musculus)6480464Fenretinide results in decreased expression of NBL1 mRNACTDPMID:16467112
Nbl1Rat5-fluorouracil decreases expressionISONBL1 (Homo sapiens)6480464Fluorouracil results in decreased expression of NBL1 mRNACTDPMID:16709241
Nbl1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of NBL1 mRNACTDPMID:24780913 and PMID:30047161
Nbl1Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of NBL1 mRNACTDPMID:28959563
Nbl1Ratacrylamide increases expressionISONBL1 (Homo sapiens)6480464Acrylamide results in increased expression of NBL1 mRNACTDPMID:32763439
Nbl1Rataflatoxin B1 increases expressionISONBL1 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of NBL1 mRNACTDPMID:22100608
Nbl1Rataflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of NBL1 mRNACTDPMID:33354967
Nbl1Ratall-trans-retinoic acid increases expressionISONBL1 (Homo sapiens)6480464Tretinoin results in increased expression of NBL1 mRNACTDPMID:17431108

1 to 20 of 110 rows

Biological Process
1 to 20 of 24 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nbl1Ratdetermination of dorsal identity involved_inISONbl1 (Mus musculus)1624291 PMID:9660951RGDPMID:9660951
Nbl1Ratdetermination of dorsal identity involved_inIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratnegative regulation of BMP signaling pathway involved_inISSUniProtKB:P412711600115GO_REF:0000024UniProtGO_REF:0000024
Nbl1Ratnegative regulation of BMP signaling pathway acts_upstream_of_or_withinIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratnegative regulation of BMP signaling pathway involved_inIEAUniProtKB:P41271 and ensembl:ENSP000003642781600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratnegative regulation of BMP signaling pathway acts_upstream_of_or_withinISONbl1 (Mus musculus)1624291 PMID:23676271RGDPMID:23676271
Nbl1Ratnegative regulation of BMP signaling pathway involved_inISONBL1 (Homo sapiens)1624291 PMID:23063586 and PMID:25561725RGDPMID:23063586 and PMID:25561725
Nbl1Ratnegative regulation of monocyte chemotaxis involved_inISONbl1 (Mus musculus)1624291 PMID:15528323RGDPMID:15528323
Nbl1Ratnegative regulation of monocyte chemotaxis involved_inIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratnervous system development involved_inIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratnervous system development involved_inISONbl1 (Mus musculus)1624291 PMID:9660951RGDPMID:9660951
Nbl1Ratneuron differentiation acts_upstream_ofISONbl1 (Mus musculus)1624291 PMID:16325379RGDPMID:16325379
Nbl1Ratneuron differentiation acts_upstream_ofIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratneuron projection morphogenesis acts_upstream_of_or_withinISONbl1 (Mus musculus)1624291 PMID:16325379RGDPMID:16325379
Nbl1Ratneuron projection morphogenesis acts_upstream_of_or_withinIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratpositive regulation of neuron differentiation acts_upstream_of_or_withinISONbl1 (Mus musculus)1624291 PMID:16325379RGDPMID:16325379
Nbl1Ratpositive regulation of neuron differentiation acts_upstream_of_or_withinIEAUniProtKB:Q61477 and ensembl:ENSMUSP000000456081600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratsequestering of BMP from receptor via BMP binding involved_inIEAUniProtKB:P41271 and ensembl:ENSP000003642781600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratsequestering of BMP from receptor via BMP binding involved_inIBAMGI:1344367 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nbl1Ratsequestering of BMP from receptor via BMP binding involved_inISONBL1 (Homo sapiens)1624291 PMID:23063586RGDPMID:23063586
1 to 20 of 24 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nbl1Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Nbl1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Nbl1Ratextracellular space located_inIEAUniProtKB:P41271 and ensembl:ENSP000003642781600115GO_REF:0000107EnsemblGO_REF:0000107
Nbl1Ratextracellular space is_active_inIBAMGI:1344337 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Nbl1Ratextracellular space located_inISONBL1 (Homo sapiens)1624291 PMID:11594460RGDPMID:11594460
Nbl1Ratextracellular space located_inISSUniProtKB:P412711600115GO_REF:0000024UniProtGO_REF:0000024
Nbl1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 11 of 11 rows

  
1 to 11 of 11 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Molecular cloning and characterization of a cDNA showing negative regulation in v-src-transformed 3Y1 rat fibroblasts. Ozaki T and Sakiyama S, Proc Natl Acad Sci U S A 1993 Apr 1;90(7):2593-7.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:7942277   PMID:9268694   PMID:9660951   PMID:10390159   PMID:11594460   PMID:15528323   PMID:16325379   PMID:22357543   PMID:23063586   PMID:23676271   PMID:25561725  



Nbl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,601,986 - 156,613,182 (-)NCBIGRCr8
mRatBN7.25151,318,752 - 151,329,948 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,318,754 - 151,338,719 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5154,015,980 - 154,027,177 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,790,290 - 155,801,487 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05155,772,293 - 155,783,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,524,569 - 157,535,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,524,513 - 157,535,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,263,765 - 161,274,897 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5149,703,598 - 149,714,771 (-)NCBICelera
Cytogenetic Map5q36NCBI
NBL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,643,229 - 19,658,452 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,596,979 - 19,658,456 (+)EnsemblGRCh38hg38GRCh38
GRCh37119,969,723 - 19,984,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,842,313 - 19,857,532 (+)NCBINCBI36Build 36hg18NCBI36
Build 34119,715,031 - 19,730,251NCBI
Celera118,296,492 - 18,311,717 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef118,215,821 - 18,231,031 (+)NCBIHuRef
CHM1_1120,078,997 - 20,094,228 (+)NCBICHM1_1
T2T-CHM13v2.0119,466,606 - 19,481,830 (+)NCBIT2T-CHM13v2.0
Nbl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,809,602 - 138,820,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,809,595 - 138,820,304 (-)EnsemblGRCm39 Ensembl
GRCm384139,082,291 - 139,093,126 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,082,284 - 139,092,993 (-)EnsemblGRCm38mm10GRCm38
MGSCv374138,638,207 - 138,648,885 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,354,368 - 138,364,941 (-)NCBIMGSCv36mm8
Celera4140,868,231 - 140,871,576 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.57NCBI
Nbl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955452308,573 - 319,989 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955452316,867 - 319,883 (+)NCBIChiLan1.0ChiLan1.0
NBL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,460,724 - 207,474,909 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11206,577,562 - 206,591,747 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,599,121 - 18,613,305 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,652,853 - 19,656,431 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,641,279 - 19,656,431 (+)Ensemblpanpan1.1panPan2
NBL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1279,040,206 - 79,102,792 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl279,041,105 - 79,102,820 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,554,895 - 75,582,497 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,607,161 - 79,634,902 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,608,223 - 79,610,312 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,425,235 - 76,452,808 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,434,195 - 77,461,836 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,503,885 - 78,531,526 (-)NCBIUU_Cfam_GSD_1.0
Nbl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505839,996,034 - 40,018,509 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364745,840,240 - 5,859,749 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364745,820,798 - 5,843,291 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NBL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,059,392 - 78,071,604 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1678,046,084 - 78,071,609 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2672,138,765 - 72,142,022 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NBL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120112,893,928 - 112,908,041 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20112,893,633 - 112,897,355 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660333,253,483 - 3,267,595 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nbl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247644,764,903 - 4,775,707 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247644,771,334 - 4,774,462 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Nbl1
41 total Variants

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:99
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000072299
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 37 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat

1 to 10 of 37 rows
AA963347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,318,773 - 151,318,925 (+)MAPPERmRatBN7.2
Rnor_6.05157,524,591 - 157,524,742NCBIRnor6.0
Rnor_5.05161,263,787 - 161,263,938UniSTSRnor5.0
Celera5149,703,620 - 149,703,771UniSTS
RH 3.4 Map51032.4UniSTS
Cytogenetic Map5q36.13UniSTS
AU047985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,326,895 - 151,327,192 (+)MAPPERmRatBN7.2
Rnor_6.05157,532,649 - 157,532,945NCBIRnor6.0
Rnor_5.05161,271,845 - 161,272,141UniSTSRnor5.0
Cytogenetic Map5q36.13UniSTS
UniSTS:224311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,319,532 - 151,319,694 (+)MAPPERmRatBN7.2
Rnor_6.05157,525,350 - 157,525,511NCBIRnor6.0
Rnor_5.05161,264,546 - 161,264,707UniSTSRnor5.0
Celera5149,704,379 - 149,704,540UniSTS
Cytogenetic Map5q36.13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000072299   ⟹   ENSRNOP00000064345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,318,754 - 151,329,948 (-)Ensembl
Rnor_6.0 Ensembl5157,524,513 - 157,535,664 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101272   ⟹   ENSRNOP00000079581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5151,318,754 - 151,338,719 (-)Ensembl
RefSeq Acc Id: NM_031609   ⟹   NP_113797
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,601,986 - 156,613,182 (-)NCBI
mRatBN7.25151,318,752 - 151,329,948 (-)NCBI
Rnor_6.05157,524,569 - 157,535,701 (-)NCBI
Rnor_5.05161,263,765 - 161,274,897 (-)NCBI
Celera5149,703,598 - 149,714,771 (-)RGD
Sequence:
Protein RefSeqs NP_113797 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB32215 (Get FASTA)   NCBI Sequence Viewer  
  AAH61833 (Get FASTA)   NCBI Sequence Viewer  
  CAA47344 (Get FASTA)   NCBI Sequence Viewer  
  EDL80903 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064345
GenBank Protein Q06880 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113797   ⟸   NM_031609
- Peptide Label: precursor
- UniProtKB: Q6P750 (UniProtKB/Swiss-Prot),   Q06880 (UniProtKB/Swiss-Prot),   A0A0G2JSZ3 (UniProtKB/TrEMBL),   A6ITK2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064345   ⟸   ENSRNOT00000072299
Ensembl Acc Id: ENSRNOP00000079581   ⟸   ENSRNOT00000101272
CTCK

Name Modeler Protein Id AA Range Protein Structure
AF-Q06880-F1-model_v2 AlphaFold Q06880 1-178 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694199
Promoter ID:EPDNEW_R4724
Type:multiple initiation site
Name:Nbl1_1
Description:neuroblastoma 1, DAN family BMP antagonist
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05157,535,676 - 157,535,736EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39429 BioCyc
Ensembl Genes ENSRNOG00000049402 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000072299 ENTREZGENE
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599381 IMAGE-MGC_LOAD
InterPro Cys_knot_C UniProtKB/Swiss-Prot
  Cystine-knot_cytokine UniProtKB/Swiss-Prot
  DAN UniProtKB/Swiss-Prot
  Neuroblast_suppress_tumour_1 UniProtKB/Swiss-Prot
KEGG Report rno:50594 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72398 IMAGE-MGC_LOAD
NCBI Gene 50594 ENTREZGENE
PANTHER GREMLIN 1 UniProtKB/Swiss-Prot
  NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1 UniProtKB/Swiss-Prot
Pfam DAN UniProtKB/Swiss-Prot
PhenoGen Nbl1 PhenoGen
PIRSF DAN_sub UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000049402 RatGTEx
SMART SM00041 UniProtKB/Swiss-Prot
UniProt A0A0G2JSZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMZ3_RAT UniProtKB/TrEMBL
  A6ITK2 ENTREZGENE, UniProtKB/TrEMBL
  NBL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P750 ENTREZGENE
UniProt Secondary Q6P750 UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-18 Nbl1  NBL1, DAN family BMP antagonist  Nbl1  neuroblastoma 1, DAN family BMP antagonist  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-07 Nbl1  neuroblastoma 1, DAN family BMP antagonist  Nbl1  neuroblastoma 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-06 Nbl1  neuroblastoma 1  Nbl1  neuroblastoma, suppression of tumorigenicity 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Nbl1  neuroblastoma, suppression of tumorigenicity 1    neuroblastoma, suppression of tumorigenicity 1   Symbol and Name status set to approved 625702 APPROVED
2002-06-10 Nbl1  neuroblastoma, suppression of tumorigenicity 1       Name updated 70585 PROVISIONAL

Note Type Note Reference
gene_domains contains a putative zinc-finger domain and a proline-rich domain 729039
gene_protein 178 amino acid residues 729039