Symbol:
Acadm
Name:
acyl-CoA dehydrogenase medium chain
RGD ID:
2012
Description:
Enables several functions, including acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding activity; and protein homodimerization activity. Involved in several processes, including fatty acid catabolic process; response to copper ion; and response to glucocorticoid. Located in mitochondrial matrix and mitochondrial membrane. Biomarker of metabolic dysfunction-associated steatotic liver disease. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADM (acyl-CoA dehydrogenase medium chain); PARTICIPATES IN fatty acid beta degradation pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; INTERACTS WITH (+)-schisandrin B; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-naphthyl isothiocyanate.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
acetyl-Coenzyme A dehydrogenase, medium chain; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, medium chain; MCAD; MCAD, medium chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase; medium-chain specific acyl-CoA dehydrogenase, mitochondrial
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ACADM (acyl-CoA dehydrogenase medium chain) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Acadm (acyl-Coenzyme A dehydrogenase, medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Acadm (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ACADM (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ACADM (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Acadm (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ACADM (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ACADM (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Acadm (acyl-CoA dehydrogenase medium chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Acadm (acyl-Coenzyme A dehydrogenase, medium chain)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
ACADM (acyl-CoA dehydrogenase medium chain)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
acadm (acyl-CoA dehydrogenase medium chain)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG12262
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
acdh-10
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
acdh-7
Alliance
DIOPT (InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
acdh-8
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
acadm
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 245,518,693 - 245,542,864 (-) NCBI GRCr8 mRatBN7.2 2 242,858,865 - 242,883,036 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 242,858,865 - 242,883,147 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 250,681,651 - 250,705,889 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 248,575,474 - 248,599,714 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 243,474,041 - 243,498,277 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 260,124,418 - 260,148,589 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 260,124,418 - 260,148,589 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 278,788,485 - 278,812,656 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 251,866,645 - 251,890,729 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 251,881,251 - 251,905,336 (-) NCBI Celera 2 234,791,302 - 234,815,446 (-) NCBI Celera RH 3.4 Map 2 1631.1 RGD Cytogenetic Map 2 q45 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Acadm Rat (+)-dexrazoxane multiple interactions ISO Acadm (Mus musculus) 6480464 [Doxorubicin co-treated with Dexrazoxane] results in increased expression of ACADM mRNA CTD PMID:26873546 Acadm Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ACADM mRNA] CTD PMID:31150632 Acadm Rat (-)-epigallocatechin 3-gallate multiple interactions ISO ACADM (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ACADM mRNA CTD PMID:22079256 Acadm Rat (1->4)-beta-D-glucan multiple interactions ISO Acadm (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ACADM mRNA CTD PMID:36331819 Acadm Rat 1,2-dichloroethane increases expression ISO Acadm (Mus musculus) 6480464 ethylene dichloride results in increased expression of ACADM mRNA CTD PMID:28960355 Acadm Rat 1,2-dimethylhydrazine multiple interactions ISO Acadm (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ACADM mRNA CTD PMID:22206623 Acadm Rat 1,2-dimethylhydrazine decreases expression ISO Acadm (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of ACADM mRNA CTD PMID:22206623 Acadm Rat 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine multiple interactions EXP 6480464 Trimetazidine promotes the reaction [Oxygen deficiency results in decreased expression of ACADM mRNA] CTD PMID:25937560 Acadm Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat 1-naphthyl isothiocyanate multiple interactions ISO Acadm (Mus musculus) 6480464 Allopurinol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ACADM mRNA] CTD PMID:33749747 Acadm Rat 1-naphthyl isothiocyanate decreases expression ISO Acadm (Mus musculus) 6480464 1-Naphthylisothiocyanate results in decreased expression of ACADM mRNA CTD PMID:33749747 Acadm Rat 17alpha-ethynylestradiol affects expression ISO Acadm (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of ACADM mRNA CTD PMID:17555576 Acadm Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ACADM mRNA CTD PMID:12075121 Acadm Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ACADM mRNA CTD PMID:16174780 Acadm Rat 17alpha-ethynylestradiol multiple interactions ISO Acadm (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ACADM mRNA CTD PMID:17942748 Acadm Rat 17alpha-ethynylestradiol increases expression ISO Acadm (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of ACADM mRNA CTD PMID:17942748 Acadm Rat 17alpha-ethynylestradiol decreases expression ISO Acadm (Mus musculus) 6480464 Ethinyl Estradiol results in decreased expression of ACADM mRNA CTD PMID:16174780 Acadm Rat 17beta-estradiol decreases expression ISO Acadm (Mus musculus) 6480464 Estradiol results in decreased expression of ACADM mRNA CTD PMID:14664709 and PMID:19484750 Acadm Rat 17beta-estradiol increases expression ISO Acadm (Mus musculus) 6480464 Estradiol results in increased expression of ACADM mRNA CTD PMID:39298647 Acadm Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of ACADM mRNA CTD PMID:26496021 Acadm Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Acadm (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Acadm Rat 2,2,2-tetramine multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein] CTD PMID:19634143 Acadm Rat 2,3,7,8-tetrabromodibenzodioxine decreases expression ISO Acadm (Mus musculus) 6480464 2 more ... CTD PMID:27604104 Acadm Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Acadm (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 and PMID:28433925 Acadm Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ACADM mRNA CTD PMID:34747641 Acadm Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Acadm (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ACADM mRNA CTD PMID:33956508 Acadm Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Acadm (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ACADM mRNA CTD PMID:21570461 and PMID:36222588 Acadm Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ACADM mRNA CTD PMID:21215274 Acadm Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Acadm (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ACADM mRNA CTD PMID:15328365 Acadm Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Acadm (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Acadm Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of ACADM mRNA CTD PMID:21346803 Acadm Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of ACADM mRNA CTD PMID:21346803 Acadm Rat 2-amino-14,16-dimethyloctadecan-3-ol decreases expression ISO ACADM (Homo sapiens) 6480464 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of ACADM protein CTD PMID:32044396 Acadm Rat 2-hydroxypropanoic acid decreases expression ISO ACADM (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ACADM mRNA CTD PMID:30851411 Acadm Rat 2-methylcholine affects expression ISO ACADM (Homo sapiens) 6480464 beta-methylcholine affects the expression of ACADM mRNA CTD PMID:21179406 Acadm Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Acadm (Mus musculus) 6480464 3 more ... CTD PMID:19467301 Acadm Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of ACADM protein CTD PMID:26597043 Acadm Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of ACADM mRNA CTD PMID:28522335 Acadm Rat 3-chloropropane-1,2-diol affects expression EXP 6480464 alpha-Chlorohydrin affects the expression of ACADM protein CTD PMID:26597043 Acadm Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Acadm (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ACADM mRNA and [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ACADM mRNA CTD PMID:23428407 and PMID:24848799 Acadm Rat 4,4'-sulfonyldiphenol increases expression ISO Acadm (Mus musculus) 6480464 bisphenol S results in increased expression of ACADM mRNA CTD PMID:39298647 Acadm Rat 5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid increases expression ISO ACADM (Homo sapiens) 6480464 acipimox results in increased expression of ACADM mRNA CTD PMID:25352640 Acadm Rat 8'-apo-beta,psi-caroten-8'-al increases expression ISO ACADM (Homo sapiens) 6480464 apocarotenal results in increased expression of ACADM mRNA CTD PMID:17034753 Acadm Rat acetylsalicylic acid increases expression ISO ACADM (Homo sapiens) 6480464 Aspirin results in increased expression of ACADM mRNA and Aspirin results in increased expression of ACADM protein CTD PMID:25743752 Acadm Rat aflatoxin B1 decreases expression ISO ACADM (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of ACADM mRNA CTD PMID:27153756 Acadm Rat aflatoxin M1 decreases expression ISO ACADM (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of ACADM mRNA CTD PMID:30928695 Acadm Rat AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of ACADM mRNA] CTD PMID:19699196 Acadm Rat AICA ribonucleotide increases expression ISO ACADM (Homo sapiens) 6480464 AICA ribonucleotide results in increased expression of ACADM mRNA and AICA ribonucleotide results in increased expression of ACADM protein CTD PMID:25743752 Acadm Rat all-trans-retinoic acid increases expression ISO ACADM (Homo sapiens) 6480464 Tretinoin results in increased expression of ACADM mRNA CTD PMID:23830798 Acadm Rat allopurinol multiple interactions ISO Acadm (Mus musculus) 6480464 Allopurinol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ACADM mRNA] CTD PMID:33749747 Acadm Rat allopurinol increases expression ISO Acadm (Mus musculus) 6480464 Allopurinol results in increased expression of ACADM mRNA CTD PMID:33749747 Acadm Rat amiodarone increases expression ISO Acadm (Mus musculus) 6480464 Amiodarone results in increased expression of ACADM mRNA CTD PMID:24489787 Acadm Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ACADM mRNA CTD PMID:16483693 Acadm Rat Aroclor 1254 decreases expression ISO Acadm (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of ACADM mRNA CTD PMID:23650126 Acadm Rat atrazine multiple interactions ISO Acadm (Mus musculus) 6480464 Atrazine promotes the reaction [[lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of ACADM mRNA] CTD PMID:24440342 Acadm Rat azoxystrobin increases expression ISO ACADM (Homo sapiens) 6480464 azoxystrobin results in increased expression of ACADM mRNA CTD PMID:33512557 Acadm Rat benzo[a]pyrene increases expression ISO Acadm (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ACADM mRNA CTD PMID:21715664 Acadm Rat benzo[a]pyrene affects methylation ISO ACADM (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ACADM promoter CTD PMID:27901495 Acadm Rat benzo[a]pyrene decreases expression ISO Acadm (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of ACADM protein CTD PMID:29145655 Acadm Rat berberine multiple interactions ISO Acadm (Mus musculus) 6480464 Berberine inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:25455889 Acadm Rat beta-hexachlorocyclohexane decreases expression ISO ACADM (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in decreased expression of ACADM mRNA and beta-hexachlorocyclohexane results in decreased expression of ACADM protein CTD PMID:28397872 Acadm Rat beta-hexachlorocyclohexane decreases expression ISO Acadm (Mus musculus) 6480464 beta-hexachlorocyclohexane results in decreased expression of ACADM mRNA and beta-hexachlorocyclohexane results in decreased expression of ACADM protein CTD PMID:28397872 Acadm Rat beta-lapachone increases expression ISO ACADM (Homo sapiens) 6480464 beta-lapachone results in increased expression of ACADM mRNA CTD PMID:38218311 Acadm Rat beta-lapachone decreases expression ISO ACADM (Homo sapiens) 6480464 beta-lapachone results in decreased expression of ACADM mRNA CTD PMID:38218311 Acadm Rat bexarotene increases expression EXP 6480464 bexarotene results in increased expression of ACADM mRNA CTD PMID:23292798 Acadm Rat bezafibrate multiple interactions ISO Acadm (Mus musculus) 6480464 Bezafibrate inhibits the reaction [CYP19A1 gene mutant form results in decreased expression of ACADM mRNA] more ... CTD PMID:11929713 and PMID:19124612 Acadm Rat bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] CTD PMID:26190035 Acadm Rat bezafibrate increases expression ISO Acadm (Mus musculus) 6480464 Bezafibrate results in increased expression of ACADM mRNA CTD PMID:19124612 Acadm Rat bis(2-chloroethyl) sulfide increases expression ISO Acadm (Mus musculus) 6480464 Mustard Gas results in increased expression of ACADM mRNA CTD PMID:15674844 Acadm Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Acadm (Mus musculus) 6480464 [Ethanol co-treated with Diethylhexyl Phthalate] results in increased expression of ACADM mRNA more ... CTD PMID:19850644 more ... Acadm Rat bis(2-ethylhexyl) phthalate increases expression ISO Acadm (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of ACADM mRNA CTD PMID:19245819 more ... Acadm Rat bis(2-ethylhexyl) phthalate increases expression ISO ACADM (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of ACADM mRNA CTD PMID:21354252 Acadm Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ACADM mRNA CTD PMID:24105817 and PMID:34947998 Acadm Rat bisphenol A increases expression ISO ACADM (Homo sapiens) 6480464 bisphenol A results in increased expression of ACADM protein CTD PMID:37567409 Acadm Rat bisphenol A increases expression ISO Acadm (Mus musculus) 6480464 bisphenol A results in increased expression of ACADM mRNA CTD PMID:37105096 Acadm Rat bisphenol A decreases expression ISO Acadm (Mus musculus) 6480464 bisphenol A results in decreased expression of ACADM mRNA CTD PMID:30566610 and PMID:33221593 Acadm Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of ACADM gene CTD PMID:28505145 Acadm Rat bisphenol A multiple interactions ISO Acadm (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Acadm Rat bisphenol A decreases expression ISO ACADM (Homo sapiens) 6480464 bisphenol A analog results in decreased expression of ACADM mRNA more ... CTD PMID:32763284 and PMID:34186270 Acadm Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ACADM mRNA CTD PMID:25181051 Acadm Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of ACADM mRNA CTD PMID:26496021 Acadm Rat bisphenol AF increases expression ISO ACADM (Homo sapiens) 6480464 bisphenol AF results in increased expression of ACADM protein CTD PMID:34186270 Acadm Rat Bisphenol B increases expression ISO ACADM (Homo sapiens) 6480464 bisphenol B results in increased expression of ACADM protein CTD PMID:34186270 Acadm Rat bisphenol F increases expression ISO ACADM (Homo sapiens) 6480464 4 more ... CTD PMID:32763284 and PMID:34186270 Acadm Rat cadmium atom increases oxidation ISO Acadm (Mus musculus) 6480464 Cadmium results in increased oxidation of ACADM protein CTD PMID:24496640 Acadm Rat cadmium dichloride increases expression ISO ACADM (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ACADM protein CTD PMID:24527689 Acadm Rat cadmium dichloride decreases expression ISO ACADM (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of ACADM mRNA CTD PMID:38568856 Acadm Rat cadmium dichloride increases expression ISO Acadm (Mus musculus) 6480464 Cadmium Chloride results in increased expression of ACADM mRNA CTD PMID:26352046 Acadm Rat calcitriol increases expression ISO ACADM (Homo sapiens) 6480464 Calcitriol results in increased expression of ACADM mRNA CTD PMID:16002434 Acadm Rat cannabidiol multiple interactions ISO Acadm (Mus musculus) 6480464 Cannabidiol inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:28935932 Acadm Rat carbon nanotube decreases expression ISO Acadm (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Acadm Rat carbon nanotube increases expression ISO Acadm (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 Acadm Rat chloroform decreases expression EXP 6480464 Chloroform results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat cholesterol multiple interactions ISO Acadm (Mus musculus) 6480464 [lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of ACADM mRNA and Atrazine promotes the reaction [[lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of ACADM mRNA] CTD PMID:24440342 Acadm Rat choline multiple interactions ISO Acadm (Mus musculus) 6480464 [Choline deficiency co-treated with Methionine deficiency] results in increased expression of ACADM mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ACADM mRNA CTD PMID:22872676 and PMID:25178843 Acadm Rat chromium(6+) affects expression ISO ACADM (Homo sapiens) 6480464 chromium hexavalent ion affects the expression of ACADM mRNA CTD PMID:30690063 Acadm Rat ciglitazone multiple interactions ISO ACADM (Homo sapiens) 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of ACADM mRNA and [ciglitazone binds to PPARG protein] which results in increased expression of ACADM mRNA CTD PMID:16197558 Acadm Rat cisplatin increases expression ISO ACADM (Homo sapiens) 6480464 Cisplatin results in increased expression of ACADM mRNA CTD PMID:27594783 Acadm Rat cisplatin multiple interactions ISO Acadm (Mus musculus) 6480464 Melatonin inhibits the reaction [Cisplatin results in decreased expression of ACADM mRNA] CTD PMID:35367536 Acadm Rat cisplatin decreases expression ISO Acadm (Mus musculus) 6480464 Cisplatin results in decreased expression of ACADM mRNA CTD PMID:35367536 Acadm Rat cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of ACADM mRNA CTD PMID:36006825 Acadm Rat cisplatin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Cisplatin results in decreased expression of ACADM mRNA] CTD PMID:36006825 Acadm Rat clenbuterol increases expression ISO Acadm (Mus musculus) 6480464 Clenbuterol results in increased expression of ACADM mRNA CTD PMID:17446185 Acadm Rat clofibrate multiple interactions ISO Acadm (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ACADM mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ACADM mRNA] CTD PMID:17585979 Acadm Rat clofibrate increases expression ISO Acadm (Mus musculus) 6480464 Clofibrate results in increased expression of ACADM mRNA CTD PMID:17585979 more ... Acadm Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of ACADM mRNA and Clofibrate results in increased expression of ACADM protein CTD PMID:11328961 more ... Acadm Rat clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACADM mRNA CTD PMID:17602206 Acadm Rat Clofop multiple interactions ISO ACADM (Homo sapiens) 6480464 [fenofibric acid binds to PPARA protein] which results in increased expression of ACADM mRNA CTD PMID:16197558 Acadm Rat copper atom multiple interactions EXP 6480464 [Fructose co-treated with Copper deficiency] results in decreased expression of ACADM mRNA CTD PMID:25813056 Acadm Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of ACADM mRNA CTD PMID:22465980 Acadm Rat copper(0) multiple interactions EXP 6480464 [Fructose co-treated with Copper deficiency] results in decreased expression of ACADM mRNA CTD PMID:25813056 Acadm Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of ACADM mRNA CTD PMID:22465980 Acadm Rat copper(II) sulfate decreases expression ISO ACADM (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of ACADM mRNA CTD PMID:19549813 Acadm Rat cyclosporin A decreases expression ISO ACADM (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ACADM mRNA CTD PMID:20106945 and PMID:25562108 Acadm Rat DDE decreases expression ISO ACADM (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of ACADM protein CTD PMID:28397872 Acadm Rat dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat dexamethasone multiple interactions ISO Acadm (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ACADM mRNA and [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ACADM mRNA CTD PMID:23428407 and PMID:24848799 Acadm Rat dexamethasone decreases expression ISO Acadm (Mus musculus) 6480464 Dexamethasone results in decreased expression of ACADM protein CTD PMID:33567340 Acadm Rat Di-n-hexyl phthalate decreases expression ISO ACADM (Homo sapiens) 6480464 di-n-hexyl phthalate results in decreased expression of ACADM mRNA CTD PMID:33043605 Acadm Rat Dibutyl phosphate affects expression ISO ACADM (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of ACADM mRNA CTD PMID:37042841 Acadm Rat dibutyl phthalate increases expression ISO Acadm (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of ACADM mRNA CTD PMID:21266533 Acadm Rat dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA CTD PMID:18636392 Acadm Rat dichloroacetic acid increases expression ISO Acadm (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of ACADM mRNA CTD PMID:28962523 Acadm Rat dicrotophos decreases expression ISO ACADM (Homo sapiens) 6480464 dicrotophos results in decreased expression of ACADM mRNA CTD PMID:28302478 Acadm Rat diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of ACADM mRNA CTD PMID:37077353 Acadm Rat dioscin multiple interactions ISO Acadm (Mus musculus) 6480464 dioscin inhibits the reaction [Ethanol results in decreased expression of ACADM protein] CTD PMID:24146112 Acadm Rat dioscin multiple interactions EXP 6480464 dioscin inhibits the reaction [Ethanol results in decreased expression of ACADM protein] CTD PMID:24146112 Acadm Rat dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of ACADM mRNA CTD PMID:25937560 Acadm Rat dioxygen multiple interactions ISO Acadm (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ACADM mRNA CTD PMID:30529165 Acadm Rat dioxygen multiple interactions EXP 6480464 Trimetazidine promotes the reaction [Oxygen deficiency results in decreased expression of ACADM mRNA] CTD PMID:25937560 Acadm Rat dorsomorphin multiple interactions EXP 6480464 dorsomorphin promotes the reaction [Phenylephrine results in decreased expression of ACADM mRNA] CTD PMID:19699196 Acadm Rat dorsomorphin decreases expression EXP 6480464 dorsomorphin results in decreased expression of ACADM mRNA CTD PMID:19699196 Acadm Rat doxorubicin multiple interactions ISO Acadm (Mus musculus) 6480464 [Doxorubicin co-treated with Dexrazoxane] results in increased expression of ACADM mRNA and SIRT6 protein inhibits the reaction [Doxorubicin results in decreased expression of ACADM mRNA] CTD PMID:26873546 and PMID:38395252 Acadm Rat doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of ACADM mRNA CTD PMID:38395252 Acadm Rat doxorubicin multiple interactions EXP 6480464 SIRT6 protein inhibits the reaction [Doxorubicin results in decreased expression of ACADM mRNA] CTD PMID:38395252 Acadm Rat doxorubicin decreases expression ISO ACADM (Homo sapiens) 6480464 Doxorubicin results in decreased expression of ACADM mRNA CTD PMID:29803840 Acadm Rat doxorubicin decreases expression ISO Acadm (Mus musculus) 6480464 Doxorubicin results in decreased expression of ACADM mRNA and Doxorubicin results in decreased expression of ACADM protein CTD PMID:26873546 and PMID:38395252 Acadm Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ACADM mRNA CTD PMID:29391264 Acadm Rat erythromycin estolate decreases expression EXP 6480464 Erythromycin Estolate results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat ethanol increases expression ISO Acadm (Mus musculus) 6480464 Ethanol results in increased expression of ACADM mRNA CTD PMID:18620774 Acadm Rat ethanol affects splicing ISO Acadm (Mus musculus) 6480464 Ethanol affects the splicing of ACADM mRNA CTD PMID:30319688 Acadm Rat ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of ACADM protein CTD PMID:24146112 Acadm Rat ethanol multiple interactions EXP 6480464 dioscin inhibits the reaction [Ethanol results in decreased expression of ACADM protein] CTD PMID:24146112 Acadm Rat ethanol decreases expression ISO Acadm (Mus musculus) 6480464 Ethanol results in decreased expression of ACADM mRNA and Ethanol results in decreased expression of ACADM protein CTD PMID:20637825 more ... Acadm Rat ethanol multiple interactions ISO Acadm (Mus musculus) 6480464 [Ethanol co-treated with Diethylhexyl Phthalate] results in increased expression of ACADM mRNA more ... CTD PMID:20637825 more ... Acadm Rat etoposide affects response to substance ISO ACADM (Homo sapiens) 6480464 ACADM protein affects the susceptibility to Etoposide CTD PMID:16217747 Acadm Rat farnesol multiple interactions ISO ACADM (Homo sapiens) 6480464 [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA CTD PMID:30611723 Acadm Rat fenofibrate increases expression ISO Acadm (Mus musculus) 6480464 Fenofibrate results in increased expression of ACADM mRNA CTD PMID:11798191 more ... Acadm Rat fenofibrate multiple interactions ISO Acadm (Mus musculus) 6480464 PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA] CTD PMID:33408297 Acadm Rat fenofibrate increases expression ISO ACADM (Homo sapiens) 6480464 Fenofibrate results in increased expression of ACADM mRNA CTD PMID:24752549 and PMID:25572481 Acadm Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of ACADM mRNA CTD PMID:18035473 Acadm Rat flutamide affects expression EXP 6480464 Flutamide affects the expression of ACADM mRNA CTD PMID:21525395 Acadm Rat flutamide decreases expression ISO Acadm (Mus musculus) 6480464 Flutamide results in decreased expression of ACADM mRNA CTD PMID:17702527 and PMID:19442681 Acadm Rat folic acid multiple interactions ISO Acadm (Mus musculus) 6480464 [1 more ... CTD PMID:22206623 and PMID:22872676 Acadm Rat folic acid decreases expression ISO Acadm (Mus musculus) 6480464 Folic Acid results in decreased expression of ACADM mRNA CTD PMID:25629700 Acadm Rat fructose multiple interactions EXP 6480464 [Fructose co-treated with Copper deficiency] results in decreased expression of ACADM mRNA CTD PMID:25813056 Acadm Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ACADM mRNA CTD PMID:22061828 Acadm Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ACADM mRNA CTD PMID:22061828 and PMID:33387578 Acadm Rat glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of ACADM mRNA CTD PMID:24136188 Acadm Rat gold atom decreases expression ISO ACADM (Homo sapiens) 6480464 Gold analog results in decreased expression of ACADM mRNA CTD PMID:36057382 Acadm Rat gold(0) decreases expression ISO ACADM (Homo sapiens) 6480464 Gold analog results in decreased expression of ACADM mRNA CTD PMID:36057382 Acadm Rat GW 4064 multiple interactions ISO ACADM (Homo sapiens) 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA CTD PMID:30611723 Acadm Rat GW 4064 decreases expression ISO ACADM (Homo sapiens) 6480464 GW 4064 results in decreased expression of ACADM mRNA CTD PMID:30611723 Acadm Rat GW 501516 multiple interactions ISO ACADM (Homo sapiens) 6480464 [GW 501516 binds to PPARD protein] which results in increased expression of ACADM mRNA CTD PMID:16197558 Acadm Rat GW 7647 increases expression ISO ACADM (Homo sapiens) 6480464 GW 7647 results in increased expression of ACADM mRNA CTD PMID:30611723 Acadm Rat GW 7647 increases expression EXP 6480464 GW 7647 results in increased expression of ACADM mRNA CTD PMID:31628012 Acadm Rat hexadecanoic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA more ... CTD PMID:26190035 Acadm Rat homocysteine increases expression ISO Acadm (Mus musculus) 6480464 Homocysteine results in increased expression of ACADM mRNA and Homocysteine results in increased expression of ACADM protein CTD PMID:26993217 Acadm Rat indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of ACADM mRNA CTD PMID:36868495 Acadm Rat inulin multiple interactions ISO Acadm (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ACADM mRNA CTD PMID:36331819 Acadm Rat isoprenaline decreases activity EXP 6480464 Isoproterenol results in decreased activity of ACADM protein CTD PMID:19826179 Acadm Rat isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADM mRNA more ... CTD PMID:25045214 and PMID:30303030 Acadm Rat isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of ACADM mRNA CTD PMID:25045214 Acadm Rat isotretinoin decreases expression ISO ACADM (Homo sapiens) 6480464 Isotretinoin results in decreased expression of ACADM mRNA CTD PMID:20436886 Acadm Rat ivermectin decreases expression ISO ACADM (Homo sapiens) 6480464 Ivermectin results in decreased expression of ACADM protein CTD PMID:32959892 Acadm Rat ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of ACADM mRNA CTD PMID:37077353 Acadm Rat L-methionine multiple interactions ISO Acadm (Mus musculus) 6480464 [Choline deficiency co-treated with Methionine deficiency] results in increased expression of ACADM mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ACADM mRNA CTD PMID:22872676 and PMID:25178843 Acadm Rat lead(0) affects expression ISO ACADM (Homo sapiens) 6480464 Lead affects the expression of ACADM mRNA CTD PMID:28903495 Acadm Rat linoleic acid increases expression EXP 6480464 Linoleic Acid results in increased expression of ACADM mRNA CTD PMID:23056435 Acadm Rat lipopolysaccharide decreases expression ISO Acadm (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of ACADM mRNA CTD PMID:18940942 Acadm Rat lithium chloride decreases expression ISO Acadm (Mus musculus) 6480464 Lithium Chloride results in decreased expression of ACADM mRNA and Lithium Chloride results in decreased expression of ACADM protein CTD PMID:26993217 Acadm Rat manganese atom multiple interactions ISO ACADM (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACADM mRNA CTD PMID:39836092 Acadm Rat manganese(0) multiple interactions ISO ACADM (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACADM mRNA CTD PMID:39836092 Acadm Rat manganese(II) chloride multiple interactions ISO ACADM (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACADM mRNA CTD PMID:39836092 Acadm Rat melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Cisplatin results in decreased expression of ACADM mRNA] CTD PMID:36006825 Acadm Rat melatonin multiple interactions ISO Acadm (Mus musculus) 6480464 Melatonin inhibits the reaction [Cisplatin results in decreased expression of ACADM mRNA] CTD PMID:35367536 Acadm Rat meldonium decreases expression ISO Acadm (Mus musculus) 6480464 3-(2 more ... CTD PMID:32389661 Acadm Rat methotrexate increases expression ISO ACADM (Homo sapiens) 6480464 Methotrexate results in increased expression of ACADM mRNA CTD PMID:17400583 Acadm Rat microcystin-LR decreases expression ISO Acadm (Mus musculus) 6480464 cyanoginosin LR results in decreased expression of ACADM protein CTD PMID:26984711 Acadm Rat miquelianin multiple interactions EXP 6480464 quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] CTD PMID:26190035 Acadm Rat mono(2-ethylhexyl) phthalate increases expression ISO Acadm (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of ACADM mRNA CTD PMID:32522588 Acadm Rat mono(2-ethylhexyl) phthalate decreases expression ISO ACADM (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of ACADM mRNA CTD PMID:38685446 Acadm Rat Monobutylphthalate increases expression ISO Acadm (Mus musculus) 6480464 monobutyl phthalate results in increased expression of ACADM mRNA CTD PMID:36736749 Acadm Rat monosodium L-glutamate multiple interactions ISO Acadm (Mus musculus) 6480464 SRT1720 inhibits the reaction [Sodium Glutamate results in increased expression of ACADM mRNA] CTD PMID:19724016 Acadm Rat monosodium L-glutamate increases expression ISO Acadm (Mus musculus) 6480464 Sodium Glutamate results in increased expression of ACADM mRNA CTD PMID:19724016 Acadm Rat Muraglitazar increases expression EXP 6480464 muraglitazar results in increased expression of ACADM mRNA CTD PMID:21515302 Acadm Rat N-methyl-4-phenylpyridinium increases expression ISO Acadm (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ACADM protein CTD PMID:26558463 Acadm Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACADM mRNA CTD PMID:17602206 Acadm Rat nickel atom decreases expression ISO ACADM (Homo sapiens) 6480464 Nickel results in decreased expression of ACADM mRNA CTD PMID:23195993 Acadm Rat nickel dichloride decreases expression ISO ACADM (Homo sapiens) 6480464 nickel chloride results in decreased expression of ACADM mRNA CTD PMID:17312168 Acadm Rat NMN zwitterion multiple interactions ISO Acadm (Mus musculus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of ACADM mRNA] CTD PMID:23834033 Acadm Rat oleic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA more ... CTD PMID:26190035 Acadm Rat oleic acid multiple interactions ISO ACADM (Homo sapiens) 6480464 [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA and [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA CTD PMID:30611723 Acadm Rat ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA CTD PMID:18636392 Acadm Rat paracetamol multiple interactions ISO Acadm (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ACADM mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ACADM mRNA] CTD PMID:17585979 Acadm Rat paracetamol decreases expression ISO ACADM (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ACADM mRNA CTD PMID:29067470 Acadm Rat paracetamol increases expression ISO Acadm (Mus musculus) 6480464 Acetaminophen results in increased expression of ACADM protein CTD PMID:21329376 Acadm Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of ACADM mRNA and Acetaminophen results in increased expression of ACADM protein CTD PMID:15800402 and PMID:33387578 Acadm Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat parathion increases expression ISO Acadm (Mus musculus) 6480464 Parathion results in increased expression of ACADM mRNA CTD PMID:34813904 Acadm Rat perfluorohexanesulfonic acid multiple interactions ISO Acadm (Mus musculus) 6480464 [2-chloro-5-nitrobenzanilide co-treated with perfluorohexanesulfonic acid] results in decreased expression of ACADM mRNA CTD PMID:39111555 Acadm Rat perfluorooctane-1-sulfonic acid affects expression ISO Acadm (Mus musculus) 6480464 perfluorooctane sulfonic acid affects the expression of ACADM mRNA CTD PMID:19429403 Acadm Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Acadm (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ACADM mRNA more ... CTD PMID:36331819 Acadm Rat perfluorooctane-1-sulfonic acid increases expression ISO Acadm (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of ACADM mRNA and perfluorooctane sulfonic acid results in increased expression of ACADM protein CTD PMID:20936131 and PMID:26178269 Acadm Rat perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of ACADM mRNA CTD PMID:18692542 Acadm Rat perfluorooctanoic acid affects expression ISO Acadm (Mus musculus) 6480464 perfluorooctanoic acid affects the expression of ACADM mRNA CTD PMID:19429403 Acadm Rat perfluorooctanoic acid increases expression ISO ACADM (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of ACADM mRNA and perfluorooctanoic acid results in increased expression of ACADM protein CTD PMID:26879310 more ... Acadm Rat perfluorooctanoic acid multiple interactions ISO Acadm (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with Dietary Fats and Unsaturated] results in increased expression of ACADM mRNA CTD PMID:23626681 Acadm Rat perfluorooctanoic acid increases expression ISO Acadm (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of ACADM mRNA and perfluorooctanoic acid results in increased expression of ACADM protein CTD PMID:17681415 more ... Acadm Rat perfluorooctanoic acid multiple interactions ISO ACADM (Homo sapiens) 6480464 [PPARA co-treated with perfluorooctanoic acid] results in increased expression of ACADM mRNA and [PPARA co-treated with perfluorooctanoic acid] results in increased expression of ACADM protein CTD PMID:19751795 Acadm Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ACADM mRNA CTD PMID:16221955 Acadm Rat phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of ACADM mRNA CTD PMID:19162173 Acadm Rat phenylephrine multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of ACADM mRNA] and dorsomorphin promotes the reaction [Phenylephrine results in decreased expression of ACADM mRNA] CTD PMID:19699196 Acadm Rat phenylephrine decreases expression EXP 6480464 Phenylephrine results in decreased expression of ACADM mRNA CTD PMID:19699196 Acadm Rat PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of ACADM mRNA CTD PMID:33945839 Acadm Rat phlorizin decreases expression ISO Acadm (Mus musculus) 6480464 Phlorhizin results in decreased expression of ACADM mRNA CTD PMID:22538082 Acadm Rat picoxystrobin increases expression ISO ACADM (Homo sapiens) 6480464 picoxystrobin results in increased expression of ACADM mRNA CTD PMID:33512557 Acadm Rat pirinixic acid multiple interactions ISO ACADM (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ACADM mRNA CTD PMID:19710929 Acadm Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ACADM mRNA and pirinixic acid results in increased expression of ACADM protein CTD PMID:15018640 more ... Acadm Rat pirinixic acid multiple interactions ISO Acadm (Mus musculus) 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of ACADM mRNA] and PPARGC1B protein inhibits the reaction [pirinixic acid results in increased expression of ACADM mRNA] CTD PMID:17932310 and PMID:20059764 Acadm Rat pirinixic acid increases expression ISO Acadm (Mus musculus) 6480464 pirinixic acid results in increased expression of ACADM mRNA and pirinixic acid results in increased expression of ACADM protein CTD PMID:11798191 more ... Acadm Rat potassium chromate decreases expression ISO ACADM (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of ACADM mRNA CTD PMID:22079256 Acadm Rat potassium chromate multiple interactions ISO ACADM (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ACADM mRNA CTD PMID:22079256 Acadm Rat potassium dichromate increases expression ISO ACADM (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of ACADM mRNA CTD PMID:11678601 Acadm Rat pterostilbene increases expression ISO ACADM (Homo sapiens) 6480464 pterostilbene results in increased expression of ACADM mRNA CTD PMID:26443543 Acadm Rat puerarin increases expression ISO Acadm (Mus musculus) 6480464 puerarin results in increased expression of ACADM mRNA CTD PMID:31273855 Acadm Rat quinidine decreases expression EXP 6480464 Quinidine results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat rac-lactic acid decreases expression ISO ACADM (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ACADM mRNA CTD PMID:30851411 Acadm Rat resveratrol multiple interactions ISO Acadm (Mus musculus) 6480464 [resveratrol co-treated with Dietary Fats] results in increased expression of ACADM mRNA and SIRT1 protein promotes the reaction [resveratrol results in increased expression of ACADM mRNA] CTD PMID:19934007 and PMID:26423427 Acadm Rat resveratrol multiple interactions ISO ACADM (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ACADM mRNA CTD PMID:23557933 Acadm Rat resveratrol increases expression ISO ACADM (Homo sapiens) 6480464 resveratrol results in increased expression of ACADM mRNA CTD PMID:26443543 Acadm Rat resveratrol increases expression ISO Acadm (Mus musculus) 6480464 resveratrol results in increased expression of ACADM mRNA CTD PMID:18755807 and PMID:19934007 Acadm Rat rimonabant affects expression ISO Acadm (Mus musculus) 6480464 Rimonabant affects the expression of ACADM mRNA CTD PMID:19030233 Acadm Rat rimonabant multiple interactions ISO Acadm (Mus musculus) 6480464 Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACADM mRNA] CTD PMID:19030233 Acadm Rat SB 431542 multiple interactions ISO ACADM (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of ACADM protein CTD PMID:37664457 Acadm Rat sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA] and TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]] CTD PMID:25045214 Acadm Rat sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ACADM protein CTD PMID:29459688 Acadm Rat sodium arsenite decreases expression ISO ACADM (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ACADM mRNA CTD PMID:38568856 Acadm Rat sodium dichromate increases expression ISO Acadm (Mus musculus) 6480464 sodium bichromate results in increased expression of ACADM mRNA CTD PMID:31558096 Acadm Rat streptozocin multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein] CTD PMID:19634143 Acadm Rat streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of ACADM protein CTD PMID:19634143 Acadm Rat sucrose multiple interactions ISO Acadm (Mus musculus) 6480464 [lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of ACADM mRNA and Atrazine promotes the reaction [[lard co-treated with Cholesterol co-treated with Sucrose] results in increased expression of ACADM mRNA] CTD PMID:24440342 Acadm Rat sulforaphane increases expression ISO Acadm (Mus musculus) 6480464 sulforaphane results in increased expression of ACADM mRNA CTD PMID:30529165 Acadm Rat tamoxifen affects expression ISO Acadm (Mus musculus) 6480464 Tamoxifen affects the expression of ACADM mRNA CTD PMID:17555576 Acadm Rat tectoridin multiple interactions ISO Acadm (Mus musculus) 6480464 tectoridin inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:20637825 Acadm Rat Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of ACADM mRNA CTD PMID:21515302 Acadm Rat testosterone multiple interactions ISO Acadm (Mus musculus) 6480464 Testosterone inhibits the reaction [Testosterone deficiency results in decreased expression of ACADM mRNA] CTD PMID:21045173 Acadm Rat testosterone decreases expression ISO Acadm (Mus musculus) 6480464 Testosterone deficiency results in decreased expression of ACADM mRNA CTD PMID:21045173 Acadm Rat tetrachloroethene increases expression ISO Acadm (Mus musculus) 6480464 Tetrachloroethylene results in increased expression of ACADM mRNA CTD PMID:28973375 Acadm Rat tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of ACADM mRNA CTD PMID:15963342 and PMID:16239168 Acadm Rat tetrachloromethane increases expression ISO Acadm (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ACADM mRNA CTD PMID:31919559 Acadm Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ACADM mRNA] CTD PMID:31150632 Acadm Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ACADM mRNA CTD PMID:17522070 and PMID:31150632 Acadm Rat tetracycline decreases expression EXP 6480464 Tetracycline results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat Theaflavin 3,3'-digallate multiple interactions ISO Acadm (Mus musculus) 6480464 theaflavin-3 and 3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of ACADM mRNA] CTD PMID:36105184 Acadm Rat theophylline decreases expression EXP 6480464 Theophylline results in decreased expression of ACADM mRNA CTD PMID:17522070 Acadm Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ACADM mRNA CTD PMID:34492290 Acadm Rat titanium dioxide decreases expression ISO Acadm (Mus musculus) 6480464 titanium dioxide results in decreased expression of ACADM mRNA CTD PMID:23557971 Acadm Rat titanium dioxide decreases methylation ISO Acadm (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ACADM gene and titanium dioxide results in decreased methylation of ACADM promoter CTD PMID:35295148 Acadm Rat tributylstannane increases expression ISO Acadm (Mus musculus) 6480464 tributyltin results in increased expression of ACADM mRNA CTD PMID:23428407 and PMID:24848799 Acadm Rat Tributyltin oxide decreases expression EXP 6480464 bis(tri-n-butyltin)oxide results in decreased expression of ACADM mRNA CTD PMID:17553608 Acadm Rat trichloroethene increases expression ISO Acadm (Mus musculus) 6480464 Trichloroethylene results in increased expression of ACADM mRNA CTD PMID:23575800 Acadm Rat triphenyl phosphate affects expression ISO ACADM (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ACADM mRNA CTD PMID:37042841 Acadm Rat triptonide decreases expression ISO Acadm (Mus musculus) 6480464 triptonide results in decreased expression of ACADM mRNA CTD PMID:33045310 Acadm Rat troglitazone increases expression ISO Acadm (Mus musculus) 6480464 troglitazone results in increased expression of ACADM protein CTD PMID:18495193 Acadm Rat troglitazone increases expression EXP 6480464 troglitazone results in increased expression of ACADM mRNA CTD PMID:21515302 Acadm Rat troglitazone decreases expression ISO Acadm (Mus musculus) 6480464 troglitazone results in decreased expression of ACADM mRNA CTD PMID:11056218 Acadm Rat valproic acid increases response to substance ISO ACADM (Homo sapiens) 6480464 ACADM gene results in increased susceptibility to Valproic Acid CTD PMID:9090694 Acadm Rat valproic acid decreases expression ISO ACADM (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ACADM protein CTD PMID:29501571 Acadm Rat valproic acid increases methylation ISO ACADM (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ACADM gene CTD PMID:29501571 Acadm Rat valproic acid increases expression ISO ACADM (Homo sapiens) 6480464 Valproic Acid results in increased expression of ACADM mRNA CTD PMID:23179753 and PMID:28001369 Acadm Rat zoledronic acid decreases expression ISO Acadm (Mus musculus) 6480464 zoledronic acid results in decreased expression of ACADM mRNA CTD PMID:28871336
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
Imported Annotations - PID (archival)
(+)-dexrazoxane (ISO) (+)-schisandrin B (EXP) (-)-epigallocatechin 3-gallate (ISO) (1->4)-beta-D-glucan (ISO) 1,2-dichloroethane (ISO) 1,2-dimethylhydrazine (ISO) 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine (EXP) 1-naphthyl isothiocyanate (EXP,ISO) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,2,2-tetramine (EXP) 2,3,7,8-tetrabromodibenzodioxine (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,4-dinitrotoluene (EXP) 2,6-dinitrotoluene (EXP) 2-amino-14,16-dimethyloctadecan-3-ol (ISO) 2-hydroxypropanoic acid (ISO) 2-methylcholine (ISO) 3,3',4,4'-tetrachlorobiphenyl (ISO) 3-chloropropane-1,2-diol (EXP) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-sulfonyldiphenol (ISO) 5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid (ISO) 8'-apo-beta,psi-caroten-8'-al (ISO) acetylsalicylic acid (ISO) aflatoxin B1 (ISO) aflatoxin M1 (ISO) AICA ribonucleotide (EXP,ISO) all-trans-retinoic acid (ISO) allopurinol (ISO) amiodarone (ISO) ammonium chloride (EXP) Aroclor 1254 (ISO) atrazine (ISO) azoxystrobin (ISO) benzo[a]pyrene (ISO) berberine (ISO) beta-hexachlorocyclohexane (ISO) beta-lapachone (ISO) bexarotene (EXP) bezafibrate (EXP,ISO) bis(2-chloroethyl) sulfide (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) cadmium atom (ISO) cadmium dichloride (ISO) calcitriol (ISO) cannabidiol (ISO) carbon nanotube (ISO) chloroform (EXP) cholesterol (ISO) choline (ISO) chromium(6+) (ISO) ciglitazone (ISO) cisplatin (EXP,ISO) clenbuterol (ISO) clofibrate (EXP,ISO) clofibric acid (EXP) Clofop (ISO) copper atom (EXP) copper(0) (EXP) copper(II) sulfate (ISO) cyclosporin A (ISO) DDE (ISO) dexamethasone (EXP,ISO) Di-n-hexyl phthalate (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (ISO) dichlorine (EXP) dichloroacetic acid (ISO) dicrotophos (ISO) diethylstilbestrol (EXP) dioscin (EXP,ISO) dioxygen (EXP,ISO) dorsomorphin (EXP) doxorubicin (EXP,ISO) endosulfan (EXP) erythromycin estolate (EXP) ethanol (EXP,ISO) etoposide (ISO) farnesol (ISO) fenofibrate (ISO) flavonoids (EXP) flutamide (EXP,ISO) folic acid (ISO) fructose (EXP) gentamycin (EXP) glafenine (EXP) gold atom (ISO) gold(0) (ISO) GW 4064 (ISO) GW 501516 (ISO) GW 7647 (EXP,ISO) hexadecanoic acid (EXP) homocysteine (ISO) indometacin (EXP) inulin (ISO) isoprenaline (EXP) isotretinoin (ISO) ivermectin (ISO) ketoconazole (EXP) L-methionine (ISO) lead(0) (ISO) linoleic acid (EXP) lipopolysaccharide (ISO) lithium chloride (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) melatonin (EXP,ISO) meldonium (ISO) methotrexate (ISO) microcystin-LR (ISO) miquelianin (EXP) mono(2-ethylhexyl) phthalate (ISO) Monobutylphthalate (ISO) monosodium L-glutamate (ISO) Muraglitazar (EXP) N-methyl-4-phenylpyridinium (ISO) N-nitrosodiethylamine (EXP) nickel atom (ISO) nickel dichloride (ISO) NMN zwitterion (ISO) oleic acid (EXP,ISO) ozone (EXP) paracetamol (EXP,ISO) parathion (ISO) perfluorohexanesulfonic acid (ISO) perfluorooctane-1-sulfonic acid (EXP,ISO) perfluorooctanoic acid (EXP,ISO) phenobarbital (EXP) phenylephrine (EXP) PhIP (EXP) phlorizin (ISO) picoxystrobin (ISO) pirinixic acid (EXP,ISO) potassium chromate (ISO) potassium dichromate (ISO) pterostilbene (ISO) puerarin (ISO) quinidine (EXP) rac-lactic acid (ISO) resveratrol (ISO) rimonabant (ISO) SB 431542 (ISO) sirolimus (EXP) sodium arsenite (EXP,ISO) sodium dichromate (ISO) streptozocin (EXP) sucrose (ISO) sulforaphane (ISO) tamoxifen (ISO) tectoridin (ISO) Tesaglitazar (EXP) testosterone (ISO) tetrachloroethene (ISO) tetrachloromethane (EXP,ISO) tetracycline (EXP) Theaflavin 3,3'-digallate (ISO) theophylline (EXP) thioacetamide (EXP) titanium dioxide (ISO) tributylstannane (ISO) Tributyltin oxide (EXP) trichloroethene (ISO) triphenyl phosphate (ISO) triptonide (ISO) troglitazone (EXP,ISO) valproic acid (ISO) zoledronic acid (ISO)
Biological Process
carboxylic acid catabolic process (IEA) cardiac muscle cell differentiation (IEA,ISO) carnitine biosynthetic process (IEA,ISO) carnitine metabolic process (IEA,ISO) carnitine metabolic process, CoA-linked (IEA,ISO) fatty acid beta-oxidation (IEA,ISO,ISS,TAS) fatty acid beta-oxidation using acyl-CoA dehydrogenase (IDA,IEA,ISO) fatty acid metabolic process (IEA) glycogen biosynthetic process (IEA,ISO) heart development (IEA,ISO) lipid metabolic process (IEA) liver development (IEA,ISO) medium-chain fatty acid catabolic process (IBA,IDA,IEA,ISO) medium-chain fatty acid metabolic process (IEA,ISO) organic acid metabolic process (IEA,ISO) post-embryonic development (IEA,ISO) regulation of gluconeogenesis (IEA,ISO) response to cold (IEA,ISO) response to copper ion (IEP) response to glucocorticoid (IEP) response to hormone (IEP) response to nutrient (IEP) response to starvation (IEA,ISO) response to xenobiotic stimulus (IEP)
1.
Transcriptional regulation by glucocorticoids of mitochondrial oxidative enzyme genes in the developing rat kidney.
Djouadi F, etal., Biochem J. 1996 Apr 15;315 ( Pt 2):555-62.
2.
Tissue-specific regulation of medium-chain acyl-CoA dehydrogenase gene by thyroid hormones in the developing rat.
Djouadi F, etal., Biochem J. 1997 May 15;324 ( Pt 1):289-94.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Acyl-CoA dehydrogenases. A mechanistic overview.
Ghisla S and Thorpe C, Eur J Biochem. 2004 Feb;271(3):494-508.
5.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
6.
Biosynthesis of four rat liver mitochondrial acyl-CoA dehydrogenases: in vitro synthesis, import into mitochondria, and processing of their precursors in a cell-free system and in cultured cells.
Ikeda Y, etal., Arch Biochem Biophys. 1987 Feb 1;252(2):662-74.
7.
Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme.
Ikeda Y, etal., J Biol Chem. 1985 Jan 25;260(2):1311-25.
8.
KEGG: Kyoto Encyclopedia of Genes and Genomes
KEGG
9.
Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid beta-oxidation.
Kim JE, etal., Biol Trace Elem Res. 2012 Dec;150(1-3):360-70. doi: 10.1007/s12011-012-9519-1. Epub 2012 Oct 18.
10.
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
11.
Improved radiation hybrid map of rat chromosome 2: colocalization of the genes encoding corticotropin-releasing hormone and IL6-receptor with quantitative trait loci regulating the inflammatory response.
Laes JF, etal., Cytogenet Cell Genet 2001;92(1-2):130-3.
12.
Mitochondrial transcription factor A is increased but expression of ATP synthase beta subunit and medium-chain acyl-CoA dehydrogenase genes are decreased in hearts of copper-deficient rats.
Mao S, etal., J Nutr. 2000 Sep;130(9):2143-50.
13.
Molecular cloning and nucleotide sequence of cDNA encoding the entire precursor of rat liver medium chain acyl coenzyme A dehydrogenase.
Matsubara Y, etal., J Biol Chem 1987 Jul 25;262(21):10104-8.
14.
Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.
Matsubara Y, etal., J Biol Chem 1989 Sep 25;264(27):16321-31.
15.
A skeletal growth defect in the puma (Felis concolor).
McMullin PF Vet Rec 1978 Oct 14;103(16):356-8.
16.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
17.
Supplementation with alpha-linolenic acid-rich diacylglycerol suppresses fatty liver formation accompanied by an up-regulation of beta-oxidation in Zucker fatty rats.
Murase T, etal., Biochim Biophys Acta. 2005 Apr 15;1733(2-3):224-31. Epub 2005 Jan 13.
18.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
19.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
20.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
21.
PID Annotation Import Pipeline
Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
23.
RefSeq and LocusLink: NCBI gene-centered resources
Pruitt KD and Maglott DR, Nucleic Acids Res. 2001 Jan 1;29(1):137-40.
24.
GOA pipeline
RGD automated data pipeline
25.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
27.
Mechanisms of ketamine action on lipid metabolism in rats.
Saranteas T, etal., Eur J Anaesthesiol. 2005 Mar;22(3):222-6.
28.
Tentative Sequence Identification Numbers
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
29.
Cloning of a cDNA for short/branched chain acyl-Coenzyme A dehydrogenase from rat and characterization of its tissue expression and substrate specificity.
Willard J, etal., Arch Biochem Biophys 1996 Jul 1;331(1):127-33.
30.
Intrinsic isomerase activity of medium-chain acyl-CoA dehydrogenase.
Zeng J and Li D, Biochemistry. 2005 May 3;44(17):6715-22.
31.
Expression and purification of His-tagged rat mitochondrial medium-chain acyl-CoA dehydrogenase wild-type and Arg256 mutant proteins.
Zeng J and Li D, Protein Expr Purif 2004 Oct;37(2):472-8.
Acadm Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 245,518,693 - 245,542,864 (-) NCBI GRCr8 mRatBN7.2 2 242,858,865 - 242,883,036 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 242,858,865 - 242,883,147 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 250,681,651 - 250,705,889 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 248,575,474 - 248,599,714 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 243,474,041 - 243,498,277 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 260,124,418 - 260,148,589 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 260,124,418 - 260,148,589 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 278,788,485 - 278,812,656 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 251,866,645 - 251,890,729 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 251,881,251 - 251,905,336 (-) NCBI Celera 2 234,791,302 - 234,815,446 (-) NCBI Celera RH 3.4 Map 2 1631.1 RGD Cytogenetic Map 2 q45 NCBI
ACADM Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 75,724,709 - 75,763,679 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 75,724,431 - 75,787,575 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 76,190,394 - 76,229,364 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 75,962,870 - 76,001,771 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 75,902,302 - 75,941,204 NCBI Celera 1 74,429,931 - 74,469,272 (+) NCBI Celera Cytogenetic Map 1 p31.1 NCBI HuRef 1 74,319,974 - 74,359,196 (+) NCBI HuRef CHM1_1 1 76,305,398 - 76,344,690 (+) NCBI CHM1_1 T2T-CHM13v2.0 1 75,561,369 - 75,600,339 (+) NCBI T2T-CHM13v2.0
Acadm Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 3 153,627,990 - 153,650,280 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 3 153,627,994 - 153,650,269 (-) Ensembl GRCm39 Ensembl GRCm38 3 153,922,353 - 153,944,643 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 3 153,922,357 - 153,944,632 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 3 153,585,323 - 153,607,396 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 3 153,859,745 - 153,881,818 (-) NCBI MGSCv36 mm8 Celera 3 160,386,018 - 160,408,092 (-) NCBI Celera Cytogenetic Map 3 H3 NCBI cM Map 3 78.77 NCBI
Acadm Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955423 17,172,779 - 17,199,090 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955423 17,173,648 - 17,199,189 (-) NCBI ChiLan1.0 ChiLan1.0
ACADM Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 151,129,587 - 151,168,926 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 150,290,108 - 150,329,365 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 74,939,477 - 74,978,815 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 76,911,763 - 76,950,840 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 76,911,763 - 76,950,840 (+) Ensembl panpan1.1 panPan2
ACADM Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 6 70,852,223 - 70,881,979 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 6 70,853,061 - 70,878,668 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 6 73,516,991 - 73,547,426 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 6 71,444,858 - 71,475,297 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 6 71,444,855 - 71,475,372 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 6 70,941,180 - 70,971,613 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 6 70,886,684 - 70,917,117 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 6 71,380,006 - 71,410,441 (-) NCBI UU_Cfam_GSD_1.0
Acadm
ACADM Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 137,541,381 - 137,595,108 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 137,541,481 - 137,575,544 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 127,513,877 - 127,547,942 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
ACADM Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 20 57,428,863 - 57,468,422 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 20 57,428,472 - 57,468,359 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666033 60,040,155 - 60,081,642 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Acadm
.
Predicted Target Of
Count of predictions: 240 Count of miRNA genes: 156 Interacting mature miRNAs: 178 Transcripts: ENSRNOT00000013238 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
631563 Hcuc3 Hepatic copper content QTL 3 3.87 liver copper amount (VT:0003065) liver copper weight to liver dry weight ratio (CMO:0001512) 2 229059610 249053267 Rat 1298075 Scl17 Serum cholesterol level QTL 17 3.4 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 2 211744537 249053267 Rat 2293833 Kiddil8 Kidney dilation QTL 8 2.9 kidney pelvis morphology trait (VT:0004194) hydronephrosis severity score (CMO:0001208) 2 219753301 247136170 Rat 1598835 Anxrr18 Anxiety related response QTL 18 2.98 body movement coordination trait (VT:0005424) number of rearing movements in an experimental apparatus (CMO:0001752) 2 200990457 245990457 Rat 1300126 Bp175 Blood pressure QTL 175 3.46 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 214226044 247136170 Rat 7207490 Bss111 Bone structure and strength QTL 111 6.4 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 2 211744537 249053267 Rat 7207484 Bss108 Bone structure and strength QTL 108 5.3 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 2 211744537 249053267 Rat 7411555 Bw132 Body weight QTL 132 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 2 223389739 249053267 Rat 9587428 Epfw6 Epididymal fat weight QTL 6 7.47 0.001 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 2 223389739 249053267 Rat 7207482 Bss107 Bone structure and strength QTL 107 7 femur strength trait (VT:0010010) femur ultimate force (CMO:0001675) 2 211744537 249053267 Rat 2293844 Kiddil7 Kidney dilation QTL 7 3.5 kidney pelvis morphology trait (VT:0004194) hydronephrosis severity score (CMO:0001208) 2 219753301 247136170 Rat 1641891 Alcrsp17 Alcohol response QTL 17 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 2 149559561 249053267 Rat 2317752 Glom23 Glomerulus QTL 23 3.6 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 2 193452645 245889826 Rat 1549836 Bss2 Bone structure and strength QTL 2 7.5 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 2 211744537 249053267 Rat 724534 Uae6 Urinary albumin excretion QTL 6 10 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 2 78665619 249053267 Rat 2317885 Alcrsp28 Alcohol response QTL 28 2.1 0.63 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 2 212828222 249053267 Rat
RH142291
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 242,859,103 - 242,859,280 (+) MAPPER mRatBN7.2 Rnor_6.0 2 260,124,657 - 260,124,833 NCBI Rnor6.0 Rnor_5.0 2 278,788,724 - 278,788,900 UniSTS Rnor5.0 RGSC_v3.4 2 251,866,882 - 251,867,058 UniSTS RGSC3.4 Celera 2 234,791,541 - 234,791,717 UniSTS RH 3.4 Map 2 1631.1 UniSTS Cytogenetic Map 2 q45 UniSTS
ACADM
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 242,861,648 - 242,861,836 (+) MAPPER mRatBN7.2 Rnor_6.0 2 260,127,202 - 260,127,389 NCBI Rnor6.0 Rnor_5.0 2 278,791,269 - 278,791,456 UniSTS Rnor5.0 RGSC_v3.4 2 251,869,427 - 251,869,614 UniSTS RGSC3.4 Celera 2 234,794,086 - 234,794,273 UniSTS Cytogenetic Map 2 q45 UniSTS
RH133158
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 2 245,539,690 - 245,539,887 (+) Marker Load Pipeline mRatBN7.2 2 242,879,862 - 242,880,059 (+) MAPPER mRatBN7.2 Rnor_6.0 2 260,145,416 - 260,145,612 NCBI Rnor6.0 Rnor_5.0 2 278,809,483 - 278,809,679 UniSTS Rnor5.0 RGSC_v3.4 2 251,887,641 - 251,887,837 UniSTS RGSC3.4 Celera 2 234,812,273 - 234,812,469 UniSTS RH 3.4 Map 2 1639.8 UniSTS Cytogenetic Map 2 q45 UniSTS
RH138389
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 242,874,262 - 242,874,390 (+) MAPPER mRatBN7.2 Rnor_6.0 2 260,139,816 - 260,139,943 NCBI Rnor6.0 Rnor_5.0 2 278,803,883 - 278,804,010 UniSTS Rnor5.0 RGSC_v3.4 2 251,882,041 - 251,882,168 UniSTS RGSC3.4 Celera 2 234,806,696 - 234,806,823 UniSTS RH 3.4 Map 2 1630.2 UniSTS Cytogenetic Map 2 q45 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000013238 ⟹ ENSRNOP00000013238
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 242,858,869 - 242,883,147 (-) Ensembl Rnor_6.0 Ensembl 2 260,124,418 - 260,148,589 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000114224 ⟹ ENSRNOP00000079047
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 242,858,865 - 242,880,647 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000116479 ⟹ ENSRNOP00000078034
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 242,858,865 - 242,880,770 (-) Ensembl
RefSeq Acc Id:
NM_016986 ⟹ NP_058682
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 245,518,693 - 245,542,864 (-) NCBI mRatBN7.2 2 242,858,865 - 242,883,036 (-) NCBI Rnor_6.0 2 260,124,418 - 260,148,589 (-) NCBI Rnor_5.0 2 278,788,485 - 278,812,656 (-) NCBI RGSC_v3.4 2 251,866,645 - 251,890,729 (-) RGD Celera 2 234,791,302 - 234,815,446 (-) NCBI
Sequence:
CCGCCCCTCTCCGCCCTCCAGGCCACGCCCCTGTGGGCGGGACCCCAGTTCGCTTAGCTTCTGCCCTGTGGTGGTCGGAGCCTGCAGAGCCAACAGAGCAGGAAGGCATCATGGCAGCAGCGCTCCGC
hide sequence
RefSeq Acc Id:
NP_058682 ⟸ NM_016986
- Peptide Label:
precursor
- UniProtKB:
P08503 (UniProtKB/Swiss-Prot), G3V796 (UniProtKB/TrEMBL), A6HWP6 (UniProtKB/TrEMBL)
- Sequence:
MAAALRRGYKVLRSVSHFECRAQHTKPSLKQEPGLGFSFELTEQQKEFQTIARKFAREEIIPVAPDYDKSGEYPFPLIKRAWELGLINTHIPESCGGLGLGTFDACLITEELAYGCTGVQTAIEANSL
hide sequence
Ensembl Acc Id:
ENSRNOP00000013238 ⟸ ENSRNOT00000013238
Ensembl Acc Id:
ENSRNOP00000078034 ⟸ ENSRNOT00000116479
Ensembl Acc Id:
ENSRNOP00000079047 ⟸ ENSRNOT00000114224
RGD ID: 13691832 Promoter ID: EPDNEW_R2356 Type: initiation region Name: Acadm_1 Description: acyl-CoA dehydrogenase medium chain SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 2 260,148,504 - 260,148,564 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2017-10-09
Acadm
acyl-CoA dehydrogenase medium chain
Acadm
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2011-07-28
Acadm
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
Acadm
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-08-29
Acadm
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-02-14
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
Acadm
acetyl-Coenzyme A dehydrogenase, medium chain
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2002-11-06
Acadm
acetyl-coenzyme A dehydrogenase, medium chain
Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain
Name updated
625702 APPROVED
2002-06-10
Acadm
Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain
Symbol and Name status set to approved
70586 APPROVED
Note Type
Note
Reference
gene_expression
expressed in liver
631724
gene_function
catalyzes the alpha,beta-dehydrogenation of acyl-CoA esters
631739
gene_homology
has high similarity to acyl-CoA dehydrogenase family members short chain acyl-CoA (SCAD), long chain acyl-CoA dehydrogenase (LCAD), and isovaleryl-CoA dehydrogenase (IVD)
631718
gene_process
plays a role in fatty acid metabolism
631739
gene_product
member of the acyl-CoA dehydrogenase family
631724
