Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rufy3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Rufy3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RUFY3 mRNA | CTD | PMID:36331819 | Rufy3 | Rat | 1,2-dichloroethane | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of RUFY3 mRNA | CTD | PMID:28960355 | Rufy3 | Rat | 17beta-estradiol | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Estradiol results in increased expression of RUFY3 mRNA | CTD | PMID:31614463 | Rufy3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RUFY3 mRNA | CTD | PMID:19933214 | Rufy3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RUFY3 mRNA | CTD | PMID:33387578 | Rufy3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RUFY3 mRNA | CTD | PMID:34747641 | Rufy3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rufy3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RUFY3 mRNA | CTD | PMID:24680724 | Rufy3 | Rat | 2-methylcholine | affects expression | ISO | RUFY3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RUFY3 mRNA | CTD | PMID:21179406 | Rufy3 | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | Rufy3 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of RUFY3 mRNA | CTD | PMID:26251327 | Rufy3 | Rat | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of RUFY3 protein | CTD | PMID:34915118 | Rufy3 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | RUFY3 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of RUFY3 gene | CTD | PMID:31601247 | Rufy3 | Rat | aflatoxin B1 | increases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of RUFY3 mRNA | CTD | PMID:19770486 | Rufy3 | Rat | aflatoxin B1 | increases methylation | ISO | RUFY3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of RUFY3 gene | CTD | PMID:28458013 | Rufy3 | Rat | all-trans-retinoic acid | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RUFY3 mRNA | CTD | PMID:23724009 | Rufy3 | Rat | all-trans-retinoic acid | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RUFY3 mRNA | CTD | PMID:33167477 | Rufy3 | Rat | antirheumatic drug | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of RUFY3 mRNA | CTD | PMID:24449571 | Rufy3 | Rat | aristolochic acid A | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of RUFY3 mRNA | CTD | PMID:33212167 | Rufy3 | Rat | arsane | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Arsenic results in decreased expression of RUFY3 mRNA | CTD | PMID:16835338 | Rufy3 | Rat | arsenic atom | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Arsenic results in decreased expression of RUFY3 mRNA | CTD | PMID:16835338 | Rufy3 | Rat | benzo[a]pyrene | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of RUFY3 mRNA | CTD | PMID:22228805 | Rufy3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RUFY3 mRNA | CTD | PMID:25181051 | Rufy3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RUFY3 mRNA | CTD | PMID:34947998 | Rufy3 | Rat | bisphenol A | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of RUFY3 mRNA | CTD | PMID:32156529 and PMID:33221593 | Rufy3 | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of RUFY3 protein | CTD | PMID:28903499 | Rufy3 | Rat | butanal | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of RUFY3 mRNA | CTD | PMID:26079696 | Rufy3 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of RUFY3 promoter | CTD | PMID:22457795 | Rufy3 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of RUFY3 mRNA | CTD | PMID:33453195 | Rufy3 | Rat | chlorpyrifos | increases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RUFY3 mRNA | CTD | PMID:37019170 | Rufy3 | Rat | copper atom | multiple interactions | ISO | RUFY3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of RUFY3 mRNA | CTD | PMID:20971185 | Rufy3 | Rat | copper atom | increases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Copper results in increased expression of RUFY3 mRNA | CTD | PMID:16629173 | Rufy3 | Rat | copper(0) | multiple interactions | ISO | RUFY3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of RUFY3 mRNA | CTD | PMID:20971185 | Rufy3 | Rat | copper(0) | increases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Copper results in increased expression of RUFY3 mRNA | CTD | PMID:16629173 | Rufy3 | Rat | cyclosporin A | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RUFY3 mRNA | CTD | PMID:20106945 more ... | Rufy3 | Rat | dibenz[a,h]anthracene | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | Rufy3 | Rat | Dibutyl phosphate | affects expression | ISO | RUFY3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of RUFY3 mRNA | CTD | PMID:37042841 | Rufy3 | Rat | diethylstilbestrol | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of RUFY3 mRNA | CTD | PMID:36621641 | Rufy3 | Rat | dorsomorphin | multiple interactions | ISO | RUFY3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RUFY3 mRNA | CTD | PMID:27188386 | Rufy3 | Rat | doxorubicin | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RUFY3 mRNA | CTD | PMID:29803840 | Rufy3 | Rat | elemental selenium | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Selenium results in decreased expression of RUFY3 mRNA | CTD | PMID:19244175 | Rufy3 | Rat | formaldehyde | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of RUFY3 mRNA | CTD | PMID:23649840 | Rufy3 | Rat | FR900359 | affects phosphorylation | ISO | RUFY3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of RUFY3 protein | CTD | PMID:37730182 | Rufy3 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of RUFY3 mRNA | CTD | PMID:33387578 | Rufy3 | Rat | methylmercury chloride | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of RUFY3 mRNA | CTD | PMID:28001369 | Rufy3 | Rat | paracetamol | affects expression | ISO | Rufy3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RUFY3 mRNA | CTD | PMID:17562736 | Rufy3 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RUFY3 mRNA | CTD | PMID:33387578 | Rufy3 | Rat | paracetamol | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RUFY3 mRNA | CTD | PMID:21420995 | Rufy3 | Rat | pentanal | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | pentanal results in decreased expression of RUFY3 mRNA | CTD | PMID:26079696 | Rufy3 | Rat | perfluorononanoic acid | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of RUFY3 mRNA | CTD | PMID:32588087 | Rufy3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rufy3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RUFY3 mRNA | CTD | PMID:36331819 | Rufy3 | Rat | phenobarbital | affects expression | ISO | Rufy3 (Mus musculus) | 6480464 | Phenobarbital affects the expression of RUFY3 mRNA | CTD | PMID:23091169 | Rufy3 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of RUFY3 mRNA | CTD | PMID:28903501 | Rufy3 | Rat | propiconazole | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | propiconazole results in decreased expression of RUFY3 mRNA | CTD | PMID:21278054 | Rufy3 | Rat | resveratrol | multiple interactions | ISO | RUFY3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of RUFY3 mRNA | CTD | PMID:23557933 | Rufy3 | Rat | SB 431542 | multiple interactions | ISO | RUFY3 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | Rufy3 | Rat | selenium atom | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Selenium results in decreased expression of RUFY3 mRNA | CTD | PMID:19244175 | Rufy3 | Rat | succimer | multiple interactions | ISO | Rufy3 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of RUFY3 mRNA | CTD | PMID:21641980 | Rufy3 | Rat | sunitinib | increases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RUFY3 mRNA | CTD | PMID:31533062 | Rufy3 | Rat | temozolomide | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of RUFY3 mRNA | CTD | PMID:31758290 | Rufy3 | Rat | testosterone enanthate | affects expression | ISO | RUFY3 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of RUFY3 mRNA | CTD | PMID:17440010 | Rufy3 | Rat | tetrachloromethane | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of RUFY3 mRNA | CTD | PMID:17484886 | Rufy3 | Rat | titanium dioxide | affects expression | ISO | Rufy3 (Mus musculus) | 6480464 | titanium dioxide affects the expression of RUFY3 mRNA | CTD | PMID:17656681 | Rufy3 | Rat | trichostatin A | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of RUFY3 mRNA | CTD | PMID:26272509 | Rufy3 | Rat | trichostatin A | multiple interactions | ISO | RUFY3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RUFY3 mRNA | CTD | PMID:27188386 | Rufy3 | Rat | triphenyl phosphate | affects expression | ISO | RUFY3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RUFY3 mRNA | CTD | PMID:37042841 | Rufy3 | Rat | triptonide | decreases expression | ISO | Rufy3 (Mus musculus) | 6480464 | triptonide results in decreased expression of RUFY3 mRNA | CTD | PMID:33045310 | Rufy3 | Rat | valproic acid | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of RUFY3 mRNA | CTD | PMID:23179753 and PMID:24383497 | Rufy3 | Rat | valproic acid | affects expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RUFY3 mRNA | CTD | PMID:25979313 | Rufy3 | Rat | vitamin E | decreases expression | ISO | RUFY3 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of RUFY3 mRNA | CTD | PMID:19244175 | |