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Gene: Tmem102 (transmembrane protein 102) Rattus norvegicus

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Symbol:

Tmem102

Name:

transmembrane protein 102

RGD ID:

1559450

Description:

Predicted to be involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; response to cytokine; and signal transduction. Predicted to act upstream of or within positive regulation of T cell chemotaxis; positive regulation of cell adhesion; and regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in cell surface. Predicted to be part of protein-containing complex. Orthologous to human TMEM102 (transmembrane protein 102); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC497937; RGD1559450; similar to hypothetical protein FLJ36878

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM102 (transmembrane protein 102)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tmem102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem102 (transmembrane protein 102)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RETNLB (resistin like beta)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TMEM102 (transmembrane protein 102)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem102 (transmembrane protein 102)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tmem102	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	tmem102	Alliance	DIOPT (OMA\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	55,022,625 - 55,025,676 (-)	NCBI		GRCr8
mRatBN7.2	10	54,523,901 - 54,525,997 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	54,523,585 - 54,525,990 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	59,186,413 - 59,188,454 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	58,674,979 - 58,677,020 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	54,182,628 - 54,184,669 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	56,410,898 - 56,413,154 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	56,410,918 - 56,412,544 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	56,155,947 - 56,160,137 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,624,941 - 56,636,020 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	53,678,163 - 53,679,762 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem102	Rat	common variable immunodeficiency		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Common variable immunodeficiency	ClinVar	PMID:28492532
Tmem102	Rat	congenital myasthenic syndrome 2A		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Congenital myasthenic syndrome 2A	ClinVar	PMID:28492532
Tmem102	Rat	dyskeratosis congenita		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita	ClinVar	PMID:28492532
Tmem102	Rat	intellectual disability		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability and mild	ClinVar
Tmem102	Rat	Li-Fraumeni syndrome		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Li-Fraumeni syndrome	ClinVar	PMID:20522432 more ...
Tmem102	Rat	very long chain acyl-CoA dehydrogenase deficiency		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Very long chain acyl-CoA dehydrogenase deficiency	ClinVar	PMID:11590124 more ...
Tmem102	Rat	Weissenbacher-Zweymuller syndrome		ISO	TMEM102 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Glossoptosis more ...	ClinVar

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem102	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	Tmem102 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM102 mRNA	CTD	PMID:36331819
Tmem102	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Tmem102 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of TMEM102 mRNA	CTD	PMID:21570461
Tmem102	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of TMEM102 mRNA	CTD	PMID:32109520
Tmem102	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Tmem102 (Mus musculus)	6480464	bisphenol S results in increased expression of TMEM102 mRNA	CTD	PMID:39298647
Tmem102	Rat	aflatoxin B1	decreases expression	EXP		6480464	Aflatoxin B1 results in decreased expression of TMEM102 mRNA	CTD	PMID:33354967
Tmem102	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of TMEM102 mRNA	CTD	PMID:35163327
Tmem102	Rat	bisphenol A	increases expression	ISO	Tmem102 (Mus musculus)	6480464	bisphenol A results in increased expression of TMEM102 mRNA	CTD	PMID:32156529
Tmem102	Rat	bisphenol F	decreases expression	ISO	Tmem102 (Mus musculus)	6480464	bisphenol F results in decreased expression of TMEM102 mRNA	CTD	PMID:38685157
Tmem102	Rat	caffeine	decreases phosphorylation	ISO	TMEM102 (Homo sapiens)	6480464	Caffeine results in decreased phosphorylation of TMEM102 protein	CTD	PMID:35688186
Tmem102	Rat	calcitriol	increases expression	ISO	TMEM102 (Homo sapiens)	6480464	Calcitriol results in increased expression of TMEM102 mRNA	CTD	PMID:21592394
Tmem102	Rat	calcitriol	multiple interactions	ISO	TMEM102 (Homo sapiens)	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of TMEM102 mRNA	CTD	PMID:21592394
Tmem102	Rat	CGP 52608	multiple interactions	ISO	TMEM102 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to TMEM102 gene]	CTD	PMID:28238834
Tmem102	Rat	Dibutyl phosphate	affects expression	ISO	TMEM102 (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of TMEM102 mRNA	CTD	PMID:37042841
Tmem102	Rat	epoxiconazole	increases expression	ISO	Tmem102 (Mus musculus)	6480464	epoxiconazole results in increased expression of TMEM102 mRNA	CTD	PMID:35436446
Tmem102	Rat	indole-3-methanol	affects expression	EXP		6480464	indole-3-carbinol affects the expression of TMEM102 mRNA	CTD	PMID:21396975
Tmem102	Rat	indole-3-methanol	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TMEM102 mRNA	CTD	PMID:22129741
Tmem102	Rat	iron dichloride	decreases expression	ISO	TMEM102 (Homo sapiens)	6480464	ferrous chloride results in decreased expression of TMEM102 mRNA	CTD	PMID:35984750
Tmem102	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TMEM102 mRNA	CTD	PMID:22129741
Tmem102	Rat	paracetamol	decreases expression	ISO	TMEM102 (Homo sapiens)	6480464	Acetaminophen results in decreased expression of TMEM102 mRNA	CTD	PMID:29067470
Tmem102	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	Tmem102 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM102 mRNA	CTD	PMID:36331819
Tmem102	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of TMEM102 mRNA	CTD	PMID:35163327
Tmem102	Rat	silicon dioxide	decreases expression	ISO	TMEM102 (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of TMEM102 mRNA	CTD	PMID:25895662
Tmem102	Rat	sunitinib	decreases expression	ISO	TMEM102 (Homo sapiens)	6480464	Sunitinib results in decreased expression of TMEM102 mRNA	CTD	PMID:31533062
Tmem102	Rat	T-2 toxin	decreases expression	EXP		6480464	T-2 Toxin results in decreased expression of TMEM102 mRNA	CTD	PMID:26141394
Tmem102	Rat	testosterone	multiple interactions	ISO	TMEM102 (Homo sapiens)	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of TMEM102 mRNA	CTD	PMID:21592394
Tmem102	Rat	testosterone	increases expression	ISO	TMEM102 (Homo sapiens)	6480464	Testosterone results in increased expression of TMEM102 mRNA	CTD	PMID:21592394
Tmem102	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of TMEM102 mRNA	CTD	PMID:34492290
Tmem102	Rat	thiram	decreases expression	ISO	TMEM102 (Homo sapiens)	6480464	Thiram results in decreased expression of TMEM102 mRNA	CTD	PMID:38568856
Tmem102	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of TMEM102 mRNA	CTD	PMID:33387578
Tmem102	Rat	urethane	decreases expression	ISO	TMEM102 (Homo sapiens)	6480464	Urethane results in decreased expression of TMEM102 mRNA	CTD	PMID:28818685

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem102	Rat	biological_process		ND		1598407	01/2009: no relevant rat data	RGD
Tmem102	Rat	positive regulation of cell adhesion	acts_upstream_of_or_within	ISO	TMEM102 (Homo sapiens)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	positive regulation of cell adhesion	acts_upstream_of_or_within	IEA	UniProtKB:Q3UPR7 and ensembl:ENSMUSP00000132164	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	positive regulation of cell adhesion	acts_upstream_of_or_within	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	positive regulation of cell adhesion	acts_upstream_of_or_within	ISO	Tmem102 (Mus musculus)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	positive regulation of T cell chemotaxis	acts_upstream_of_or_within	ISO	Tmem102 (Mus musculus)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	positive regulation of T cell chemotaxis	acts_upstream_of_or_within	IEA	UniProtKB:Q3UPR7 and ensembl:ENSMUSP00000132164	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	positive regulation of T cell migration	acts_upstream_of_or_within	ISO	TMEM102 (Homo sapiens)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	positive regulation of T cell migration	acts_upstream_of_or_within	IEA	UniProtKB:Q3UPR7 and ensembl:ENSMUSP00000132164	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	positive regulation of T cell migration	acts_upstream_of_or_within	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	positive regulation of T cell migration	acts_upstream_of_or_within	ISO	Tmem102 (Mus musculus)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	involved_in	ISO	TMEM102 (Homo sapiens)	1624291	PMID:17828305	RGD	PMID:17828305
Tmem102	Rat	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	involved_in	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	regulation of peptidyl-tyrosine phosphorylation	acts_upstream_of_or_within	ISO	Tmem102 (Mus musculus)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	response to cytokine	involved_in	ISO	TMEM102 (Homo sapiens)	1624291	PMID:17828305	RGD	PMID:17828305
Tmem102	Rat	response to cytokine	involved_in	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	signal transduction	involved_in	ISO	TMEM102 (Homo sapiens)	1624291	PMID:17828305	RGD	PMID:17828305
Tmem102	Rat	signal transduction	involved_in	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem102	Rat	cell surface	located_in	ISO	TMEM102 (Homo sapiens)	1624291	PMID:17828305	RGD	PMID:17828305
Tmem102	Rat	cell surface	located_in	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem102	Rat	mitochondrion	located_in	IEA	GO:1901028	1600115	GO_REF:0000108	GOC	GO_REF:0000108
Tmem102	Rat	protein-containing complex	part_of	ISO	TMEM102 (Homo sapiens)	1624291	PMID:23620790	RGD	PMID:23620790
Tmem102	Rat	protein-containing complex	part_of	IEA	UniProtKB:Q8N9M5 and ensembl:ENSP00000315387	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem102	Rat	protein binding	enables	ISO	TMEM102 (Homo sapiens)	1624291	UniProtKB:P32927 more ...	RGD	PMID:17828305 and PMID:32296183

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
2.	Comprehensive gene review and curation	RGD comprehensive gene curation

PMID:17828305	PMID:23620790

Tmem102
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	55,022,625 - 55,025,676 (-)	NCBI		GRCr8
mRatBN7.2	10	54,523,901 - 54,525,997 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	54,523,585 - 54,525,990 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	59,186,413 - 59,188,454 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	58,674,979 - 58,677,020 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	54,182,628 - 54,184,669 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	56,410,898 - 56,413,154 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	56,410,918 - 56,412,544 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	56,155,947 - 56,160,137 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,624,941 - 56,636,020 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	53,678,163 - 53,679,762 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

TMEM102
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	7,435,435 - 7,437,679 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	7,435,435 - 7,437,679 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	7,338,754 - 7,340,998 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,279,486 - 7,281,722 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	7,364,650 - 7,366,886 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,232,706 - 7,234,942 (+)	NCBI		HuRef
CHM1_1	17	7,347,856 - 7,350,092 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	7,339,490 - 7,341,734 (+)	NCBI		T2T-CHM13v2.0

Tmem102
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,694,421 - 69,696,450 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	69,694,429 - 69,696,450 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	69,803,595 - 69,805,624 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,803,603 - 69,805,624 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,617,097 - 69,619,126 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	70,387,710 - 70,389,731 (-)	NCBI		MGSCv36	mm8
MGSCv36	11	69,619,798 - 69,621,819 (-)	NCBI		MGSCv36	mm8
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.88	NCBI

Tmem102
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	9,489,867 - 9,493,275 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	9,489,867 - 9,493,275 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM102
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	15,031,670 - 15,034,292 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	16,997,475 - 17,000,624 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	7,469,096 - 7,471,645 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	7,455,716 - 7,457,947 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,455,716 - 7,457,947 (+)	Ensembl	panpan1.1		panPan2

TMEM102
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,365,331 - 32,367,785 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,366,159 - 32,367,771 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	32,503,484 - 32,505,881 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,471,056 - 32,473,453 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,471,827 - 32,473,439 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,436,290 - 32,438,687 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,395,022 - 32,397,419 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,572,290 - 32,574,687 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem102
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	47,243,120 - 47,246,387 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	718,923 - 720,553 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	718,513 - 720,553 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM102
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,739,238 - 52,741,322 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,738,942 - 52,749,326 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,011,104 - 55,013,288 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM102
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	6,811,966 - 6,814,303 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	6,812,203 - 6,814,961 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	14,594,091 - 14,596,295 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem102
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	10,046,666 - 10,052,108 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	10,047,087 - 10,049,324 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Tmem102
8 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	86
Count of miRNA genes:	75
Interacting mature miRNAs:	77
Transcripts:	ENSRNOT00000020578
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35392457	63642539	Rat
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
9589136	Insul27	Insulin level QTL 27	10.46	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	10	11474010	56474010	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	35710580	68663659	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
152025227	Bw195	Body weight QTL 195	5.73		body mass (VT:0001259)		10	46989699	68663659	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15275955	60275955	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	49444551	81709989	Rat
152025224	Bw193	Body weight QTL 193	6.47		body mass (VT:0001259)		10	51663405	75085664	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	41142633	86142633	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
1578762	Toxo1	Toxoplasma gondii resistance QTL 1			brain integrity trait (VT:0010579)	percentage of study population displaying Toxoplasma gondii brain cysts at a point in time (CMO:0002028)	10	52200030	59378278	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	53797494	98952626	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41333258	86333258	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18167841	63167841	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21329805	61345413	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28453136	73453136	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35392267	64155584	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29299504	64155584	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	26944628	71944628	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42323132	87323132	Rat
9590310	Scort19	Serum corticosterone level QTL 19	6.3	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
10402859	Bp381	Blood pressure QTL 381		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42323132	87323132	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
2306787	Ean3	Experimental allergic neuritis QTL 3	3.1		nervous system integrity trait (VT:0010566)	body weight loss (CMO:0001399)	10	53797385	66979128	Rat
6893352	Bw100	Body weight QTL 100	0.33	0.6	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
1354585	Eae18a	Experimental allergic encephalomyelitis QTL 18a	7.5	0.0004	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	10	53797385	58445852	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15028513	60430477	Rat
6893350	Bw99	Body weight QTL 99	0.87	0.16	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	26521957	61345413	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	19606483	64606483	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
8552805	Bw145	Body weight QTL 145	2.2		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	10	41944526	78307017	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	49444551	81709989	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
9590268	Scort13	Serum corticosterone level QTL 13	3.26	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49444551	81709989	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	42876766	79813922	Rat
2292441	Bp308	Blood pressure QTL 308			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	19606483	64606483	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	7	10	44	85	90	59	25	59	6	168	51	30	45	60	31


RefSeq Transcripts	NM_001398846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001079550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020578 ⟹ ENSRNOP00000020578

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	54,523,585 - 54,525,990 (-)	Ensembl
Rnor_6.0 Ensembl	10	56,410,918 - 56,412,544 (-)	Ensembl

RefSeq Acc Id:

NM_001398846 ⟹ NP_001385775

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	55,022,625 - 55,024,668 (-)	NCBI
mRatBN7.2	10	54,523,901 - 54,525,944 (-)	NCBI

RefSeq Acc Id:

XM_039087314 ⟹ XP_038943242

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	55,022,625 - 55,025,676 (-)	NCBI
mRatBN7.2	10	54,523,901 - 54,525,997 (-)	NCBI


Protein RefSeqs	NP_001385775	(Get FASTA)	NCBI Sequence Viewer
	XP_038943242	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020578.8

Ensembl Acc Id:

ENSRNOP00000020578 ⟸ ENSRNOT00000020578

RefSeq Acc Id:	XP_038943242 ⟸ XM_039087314
- Peptide Label:	isoform X1
- UniProtKB:	F1M0L2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001385775 ⟸ NM_001398846
- UniProtKB:	F1M0L2 (UniProtKB/TrEMBL)

Protein Domains

Mab-21-like HhH/H2TH-like

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M0L2-F1-model_v2	AlphaFold	F1M0L2	1-507	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-24515	BioCyc
Ensembl Genes	ENSRNOG00000015057	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020578.8	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1410.40	UniProtKB/TrEMBL
InterPro	Mab-21_dom	UniProtKB/TrEMBL
	Mab-21_HhH/H2TH-like	UniProtKB/TrEMBL
NCBI Gene	497937	ENTREZGENE
PANTHER	CELL FATE DETERMINING PROTEIN MAB21-RELATED	UniProtKB/TrEMBL
	PTHR10656:SF48	UniProtKB/TrEMBL
Pfam	Mab-21_C	UniProtKB/TrEMBL
PhenoGen	Tmem102	PhenoGen
RatGTEx	ENSRNOG00000015057	RatGTEx
SMART	Mab-21	UniProtKB/TrEMBL
UniProt	F1M0L2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Tmem102	transmembrane protein 102	RGD1559450_predicted	similar to hypothetical protein FLJ36878 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1559450_predicted	similar to hypothetical protein FLJ36878 (predicted)	LOC497937	similar to hypothetical protein FLJ36878	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC497937	similar to hypothetical protein FLJ36878			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar