Nub1 (negative regulator of ubiquitin-like proteins 1) - Rat Genome Database

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Gene: Nub1 (negative regulator of ubiquitin-like proteins 1) Rattus norvegicus
Analyze
Symbol: Nub1
Name: negative regulator of ubiquitin-like proteins 1
RGD ID: 1359489
Description: Predicted to be involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; response to tumor necrosis factor; and response to type II interferon. Predicted to act upstream of or within proteasomal protein catabolic process. Predicted to be located in Lewy body; cytosol; and nuclear lumen. Orthologous to human NUB1 (negative regulator of ubiquitin like proteins 1); PARTICIPATES IN neddylation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BS4; NEDD8 ultimate buster 1; NEDD8 ultimate buster-1; NY-REN-18 antigen; NYREN18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8411,335,376 - 11,366,263 (-)NCBIGRCr8
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,589,502 - 15,619,758 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,409,700 - 11,439,956 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,761,499 - 9,791,741 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Celera46,058,478 - 6,088,841 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nub1Ratlethal congenital glycogen storage disease of heart  ISONUB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Lethal congenital glycogen storage disease of heartClinVarPMID:28492532
Nub1Ratlong QT syndrome  ISONUB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:10973849 more ...

1 to 20 of 58 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nub1Rat1,10-phenanthroline increases expressionISONUB1 (Homo sapiens)64804641 and 10-phenanthroline results in increased expression of NUB1 mRNACTDPMID:19502547
Nub1Rat1,2-dimethylhydrazine increases expressionISONub1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of NUB1 mRNACTDPMID:22206623
Nub1Rat1,2-dimethylhydrazine multiple interactionsISONub1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of NUB1 mRNACTDPMID:22206623
Nub1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONub1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NUB1 mRNACTDPMID:21570461
Nub1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NUB1 mRNACTDPMID:33387578
Nub1Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of NUB1 mRNACTDPMID:21346803
Nub1Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NUB1 mRNACTDPMID:36041667
Nub1Rat5-aza-2'-deoxycytidine affects expressionISONUB1 (Homo sapiens)6480464Decitabine affects the expression of NUB1 mRNACTDPMID:23300844
Nub1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of NUB1 mRNACTDPMID:24780913 and PMID:30047161
Nub1Ratacrolein multiple interactionsISONUB1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of NUB1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of NUB1 mRNACTDPMID:32699268
Nub1Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of NUB1 mRNACTDPMID:28959563
Nub1Ratall-trans-retinoic acid increases expressionISONUB1 (Homo sapiens)6480464Tretinoin results in increased expression of NUB1 mRNACTDPMID:21934132
Nub1Ratalpha-pinene multiple interactionsISONUB1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of NUB1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of NUB1 mRNACTDPMID:32699268
Nub1Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of NUB1 mRNACTDPMID:30047161
Nub1Ratantirheumatic drug decreases expressionISONUB1 (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of NUB1 mRNACTDPMID:24449571
Nub1Ratarsane affects methylationISONUB1 (Homo sapiens)6480464Arsenic affects the methylation of NUB1 geneCTDPMID:25304211
Nub1Ratarsenic atom affects methylationISONUB1 (Homo sapiens)6480464Arsenic affects the methylation of NUB1 geneCTDPMID:25304211
Nub1Ratavobenzone increases expressionISONUB1 (Homo sapiens)6480464avobenzone results in increased expression of NUB1 mRNACTDPMID:31016361
Nub1Ratbenzo[a]pyrene increases expressionISONub1 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of NUB1 mRNACTDPMID:21715664
Nub1Ratbis(2-ethylhexyl) phthalate decreases expressionISONub1 (Mus musculus)6480464Diethylhexyl Phthalate results in decreased expression of NUB1 mRNACTDPMID:33754040

1 to 20 of 58 rows

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nub1Ratcytosol located_inIEAUniProtKB:Q9Y5A7 and ensembl:ENSP000004542641600115GO_REF:0000107EnsemblGO_REF:0000107
Nub1Ratcytosol located_inISONUB1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Nub1Ratcytosol located_inIEAUniProtKB:H3BM74 and ensembl:ENSP000004542641600115GO_REF:0000107EnsemblGO_REF:0000107
Nub1RatLewy body located_inISONub1 (Mus musculus)1624291 PMID:26797281RGDPMID:26797281
Nub1Ratnucleolus located_inIEAUniProtKB:Q9Y5A7 and ensembl:ENSP000004542641600115GO_REF:0000107EnsemblGO_REF:0000107
Nub1Ratnucleolus located_inISONUB1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Nub1Ratnucleolus located_inIEAUniProtKB:H3BM74 and ensembl:ENSP000004542641600115GO_REF:0000107EnsemblGO_REF:0000107
Nub1Ratnucleoplasm located_inIEAUniProtKB:H3BM74 and ensembl:ENSP000004542641600115GO_REF:0000107EnsemblGO_REF:0000107
Nub1Ratnucleoplasm located_inISONUB1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Nub1Ratnucleoplasm located_inIEAUniProtKB:Q9Y5A7 and ensembl:ENSP000004542641600115GO_REF:0000107EnsemblGO_REF:0000107
Nub1Ratnucleus located_inISONub1 (Mus musculus)1624291 PMID:26797281RGDPMID:26797281
1 to 11 of 11 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nub1Ratprotein binding enablesISONUB1 (Homo sapiens)1624291UniProtKB:O15205 more ...RGDPMID:12374762 more ...

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nub1Ratneddylation pathway  ISS 1559298 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression. Kito K, etal., J Biol Chem 2001 Jun 8;276(23):20603-9. Epub 2001 Mar 19.
3. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Parry G and Estelle M, Semin Cell Dev Biol. 2004 Apr;15(2):221-9.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:16707496   PMID:22965877  



Nub1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8411,335,376 - 11,366,263 (-)NCBIGRCr8
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,589,502 - 15,619,758 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,409,700 - 11,439,956 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,761,499 - 9,791,741 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Celera46,058,478 - 6,088,841 (-)NCBICelera
Cytogenetic Map4q11NCBI
NUB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,341,812 - 151,378,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7151,341,772 - 151,378,449 (+)EnsemblGRCh38hg38GRCh38
GRCh377151,038,898 - 151,075,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,669,791 - 150,706,468 (+)NCBINCBI36Build 36hg18NCBI36
Celera7145,596,247 - 145,632,781 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7144,850,514 - 144,887,070 (+)NCBIHuRef
CHM1_17151,047,250 - 151,083,821 (+)NCBICHM1_1
T2T-CHM13v2.07152,514,799 - 152,551,295 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,368,354 - 150,404,911 (+)NCBI
Nub1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,890,813 - 24,915,376 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl524,890,530 - 24,915,376 (+)EnsemblGRCm39 Ensembl
GRCm38524,685,815 - 24,710,378 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,685,532 - 24,710,378 (+)EnsemblGRCm38mm10GRCm38
MGSCv37524,191,633 - 24,216,373 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36524,196,041 - 24,220,443 (+)NCBIMGSCv36mm8
Celera521,642,444 - 21,667,264 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.93NCBI
Nub1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,709,791 - 5,739,079 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,709,791 - 5,737,620 (+)NCBIChiLan1.0ChiLan1.0
NUB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,762,530 - 187,799,621 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,772,796 - 39,809,887 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07142,927,730 - 142,964,475 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17155,079,171 - 155,115,913 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,079,243 - 155,114,676 (+)Ensemblpanpan1.1panPan2
NUB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,355,237 - 15,382,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,352,476 - 15,381,095 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,962,876 - 15,989,492 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01617,077,383 - 17,104,127 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1617,075,097 - 17,104,127 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11615,449,341 - 15,475,957 (+)NCBIUMICH_Zoey_3.1
Nub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,146,984 - 6,177,063 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365276,726,357 - 6,755,318 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365276,726,363 - 6,756,445 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl185,899,568 - 5,928,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1185,899,566 - 5,928,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,247,107 - 6,274,794 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,525,757 - 119,559,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,525,932 - 119,560,886 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607215,496,939 - 15,530,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nub1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,315,381 - 5,345,801 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248005,314,203 - 5,345,301 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Nub1
217 total Variants

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:65
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000045311
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat

1 to 10 of 28 rows
D4Rat144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,495,201 - 10,495,445 (+)MAPPERmRatBN7.2
Rnor_6.047,023,217 - 7,023,460NCBIRnor6.0
Rnor_5.047,035,728 - 7,035,971UniSTSRnor5.0
RGSC_v3.445,874,672 - 5,874,916RGDRGSC3.4
RGSC_v3.445,874,673 - 5,874,916UniSTSRGSC3.4
RGSC_v3.145,874,588 - 5,874,945RGD
Celera46,111,278 - 6,111,521UniSTS
SHRSP x BN Map40.0UniSTS
SHRSP x BN Map40.0RGD
Cytogenetic Map4q11UniSTS
D4Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8411,340,159 - 11,340,265 (+)Marker Load Pipeline
mRatBN7.2410,447,700 - 10,447,806 (+)MAPPERmRatBN7.2
Rnor_6.046,955,148 - 6,955,253NCBIRnor6.0
Rnor_5.046,968,758 - 6,968,863UniSTSRnor5.0
RGSC_v3.445,825,098 - 5,825,203UniSTSRGSC3.4
RGSC_v3.445,825,097 - 5,825,203RGDRGSC3.4
RGSC_v3.445,824,765 - 5,824,871RGDRGSC3.4
RGSC_v3.445,824,766 - 5,824,871UniSTSRGSC3.4
RGSC_v3.145,825,098 - 5,825,203RGD
RH 3.4 Map414.0RGD
RH 3.4 Map414.0UniSTS
RH 2.0 Map463.2RGD
Cytogenetic Map4q11UniSTS
RH128463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,019 - 10,443,209 (+)MAPPERmRatBN7.2
Rnor_6.046,950,467 - 6,950,656NCBIRnor6.0
Rnor_5.046,964,077 - 6,964,266UniSTSRnor5.0
RGSC_v3.445,820,085 - 5,820,274UniSTSRGSC3.4
Celera46,058,075 - 6,058,264UniSTS
Cytogenetic Map4q11UniSTS
RH128761  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,580 - 10,443,766 (+)MAPPERmRatBN7.2
Rnor_6.046,951,028 - 6,951,213NCBIRnor6.0
Rnor_5.046,964,638 - 6,964,823UniSTSRnor5.0
RGSC_v3.445,820,646 - 5,820,831UniSTSRGSC3.4
Celera46,058,636 - 6,058,821UniSTS
Cytogenetic Map4q11UniSTS
RH138616  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,448,936 - 10,449,117 (+)MAPPERmRatBN7.2
Rnor_6.046,956,381 - 6,956,561NCBIRnor6.0
Rnor_5.046,969,991 - 6,970,171UniSTSRnor5.0
RGSC_v3.445,826,331 - 5,826,511UniSTSRGSC3.4
Celera46,064,102 - 6,064,282UniSTS
Cytogenetic Map4q11UniSTS
RH139609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,184 - 10,443,376 (+)MAPPERmRatBN7.2
Rnor_6.046,950,632 - 6,950,823NCBIRnor6.0
Rnor_5.046,964,242 - 6,964,433UniSTSRnor5.0
RGSC_v3.445,820,250 - 5,820,441UniSTSRGSC3.4
Celera46,058,240 - 6,058,431UniSTS
Cytogenetic Map4q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000045311   ⟹   ENSRNOP00000048314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,444,031 - 10,473,694 (-)Ensembl
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098051   ⟹   ENSRNOP00000086699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,442,917 - 10,471,056 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108045   ⟹   ENSRNOP00000078815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,442,919 - 10,470,461 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115102   ⟹   ENSRNOP00000076727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,442,917 - 10,472,315 (-)Ensembl
RefSeq Acc Id: NM_001013925   ⟹   NP_001013947
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,882 - 11,366,146 (-)NCBI
mRatBN7.2410,443,423 - 10,473,689 (-)NCBI
Rnor_6.046,950,870 - 6,981,400 (-)NCBI
Rnor_5.046,964,480 - 6,994,708 (-)NCBI
RGSC_v3.445,820,488 - 5,850,809 (-)RGD
Celera46,058,478 - 6,088,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_039107214   ⟹   XP_038963142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,376 - 11,366,263 (-)NCBI
mRatBN7.2410,442,917 - 10,473,681 (-)NCBI
RefSeq Acc Id: XM_039107215   ⟹   XP_038963143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,376 - 11,355,597 (-)NCBI
mRatBN7.2410,442,917 - 10,463,139 (-)NCBI
RefSeq Acc Id: XM_063285691   ⟹   XP_063141761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,376 - 11,366,065 (-)NCBI
RefSeq Acc Id: NP_001013947   ⟸   NM_001013925
- UniProtKB: Q5XIT4 (UniProtKB/TrEMBL),   A0A8I6A4A9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048314   ⟸   ENSRNOT00000045311
RefSeq Acc Id: XP_038963142   ⟸   XM_039107214
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4A9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963143   ⟸   XM_039107215
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000078815   ⟸   ENSRNOT00000108045
Name Modeler Protein Id AA Range Protein Structure
AF-F7ES73-F1-model_v2 AlphaFold F7ES73 1-612 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 37 of 37 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46056 BioCyc
Ensembl Genes ENSRNOG00000009282 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045311.5 UniProtKB/TrEMBL
  ENSRNOT00000098051.1 UniProtKB/TrEMBL
  ENSRNOT00000108045.1 UniProtKB/TrEMBL
  ENSRNOT00000115102.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131376 IMAGE-MGC_LOAD
InterPro NUB1 UniProtKB/TrEMBL
  NUB1_ubiquitin-like_dom UniProtKB/TrEMBL
  TPR-like_helical_dom UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:296731 UniProtKB/TrEMBL
MGC_CLONE MGC:94244 IMAGE-MGC_LOAD
NCBI Gene 296731 ENTREZGENE
PANTHER NEDD8 ULTIMATE BUSTER 1 UniProtKB/TrEMBL
  PTHR12948 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  Ubiquitin_5 UniProtKB/TrEMBL
PhenoGen Nub1 PhenoGen
PROSITE UBA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009282 RatGTEx
SMART UBA UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  UBA_like UniProtKB/TrEMBL
UniProt A0A8I5Y4X4_RAT UniProtKB/TrEMBL
  A0A8I5ZLQ1_RAT UniProtKB/TrEMBL
  A0A8I6A4A9 ENTREZGENE, UniProtKB/TrEMBL
  A6K528_RAT UniProtKB/TrEMBL
  A6K529_RAT UniProtKB/TrEMBL
  A6K530_RAT UniProtKB/TrEMBL
  F7ES73_RAT UniProtKB/TrEMBL
  Q5XIT4 ENTREZGENE, UniProtKB/TrEMBL
1 to 37 of 37 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Nub1  negative regulator of ubiquitin-like proteins 1  Nub1  NEDD8 ultimate buster-1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Nub1  NEDD8 ultimate buster-1      Symbol and Name status set to provisional 70820 PROVISIONAL