Nub1 (negative regulator of ubiquitin like proteins 1) - Rat Genome Database

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Gene: Nub1 (negative regulator of ubiquitin like proteins 1) Chinchilla lanigera
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Symbol: Nub1
Name: negative regulator of ubiquitin like proteins 1
RGD ID: 8928607
Description: INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); proteasomal protein catabolic process (ortholog); protein ubiquitination (ortholog); ASSOCIATED WITH lethal congenital glycogen storage disease of heart (ortholog); long QT syndrome (ortholog); FOUND IN cytosol (ortholog); Lewy body (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: negative regulator of ubiquitin-like proteins 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,709,791 - 5,739,079 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,709,791 - 5,737,620 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
Lewy body  (ISO)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Nub1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,709,791 - 5,739,079 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,709,791 - 5,737,620 (+)NCBIChiLan1.0ChiLan1.0
NUB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,341,812 - 151,378,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7151,341,772 - 151,378,449 (+)EnsemblGRCh38hg38GRCh38
GRCh377151,038,898 - 151,075,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,669,791 - 150,706,468 (+)NCBINCBI36hg18NCBI36
Celera7145,596,247 - 145,632,781 (+)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7144,850,514 - 144,887,070 (+)NCBIHuRef
CHM1_17151,047,250 - 151,083,821 (+)NCBICHM1_1
T2T-CHM13v2.07152,514,799 - 152,551,295 (+)NCBI
CRA_TCAGchr7v27150,368,354 - 150,404,911 (+)NCBI
Nub1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,890,813 - 24,915,376 (+)NCBIGRCm39mm39
GRCm39 Ensembl524,890,530 - 24,915,376 (+)Ensembl
GRCm38524,685,815 - 24,710,378 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,685,532 - 24,710,378 (+)EnsemblGRCm38mm10GRCm38
MGSCv37524,191,633 - 24,216,373 (+)NCBIGRCm37mm9NCBIm37
MGSCv36524,196,041 - 24,220,443 (+)NCBImm8
Celera521,642,444 - 21,667,264 (+)NCBICelera
Cytogenetic Map5A3NCBI
Nub1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)Ensembl
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Celera46,058,478 - 6,088,841 (-)NCBICelera
Cytogenetic Map4q11NCBI
NUB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17155,079,171 - 155,115,913 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,079,243 - 155,114,676 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07142,927,730 - 142,964,475 (+)NCBIMhudiblu_PPA_v0panPan3
NUB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,355,237 - 15,382,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,352,476 - 15,381,095 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,962,876 - 15,989,492 (+)NCBI
ROS_Cfam_1.01617,077,383 - 17,104,127 (+)NCBI
ROS_Cfam_1.0 Ensembl1617,075,097 - 17,104,127 (+)Ensembl
UMICH_Zoey_3.11615,449,341 - 15,475,957 (+)NCBI
Nub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,146,984 - 6,177,063 (-)NCBI
SpeTri2.0NW_0049365276,726,363 - 6,756,445 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl185,899,567 - 5,928,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1185,899,566 - 5,928,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,247,107 - 6,274,794 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,525,757 - 119,559,412 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,525,932 - 119,560,886 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607215,496,939 - 15,530,260 (+)NCBIVero_WHO_p1.0
Nub1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,315,381 - 5,345,801 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248005,314,203 - 5,345,301 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001582   ⟹   ENSCLAP00000001539
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554915,709,791 - 5,739,079 (+)Ensembl
RefSeq Acc Id: XM_005404832   ⟹   XP_005404889
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,709,791 - 5,737,620 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404889 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005404889   ⟸   XM_005404832
- Sequence:
RefSeq Acc Id: ENSCLAP00000001539   ⟸   ENSCLAT00000001582
Protein Domains
UBA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001153 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000001539 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001582 UniProtKB/TrEMBL
InterPro NUB1 UniProtKB/TrEMBL
  NUB1_ubiquitin-like_dom UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Nub1 ENTREZGENE
PANTHER PTHR12948 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  Ubiquitin_5 UniProtKB/TrEMBL
PROSITE UBA UniProtKB/TrEMBL
SMART UBA UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8C2UPQ4_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Nub1  negative regulator of ubiquitin like proteins 1    negative regulator of ubiquitin-like proteins 1  Symbol and/or name change 5135510 APPROVED