Tada2a (transcriptional adaptor 2A) - Rat Genome Database

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Gene: Tada2a (transcriptional adaptor 2A) Rattus norvegicus
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Symbol: Tada2a
Name: transcriptional adaptor 2A
RGD ID: 1309959
Description: Predicted to enable chromatin binding activity and transcription coactivator activity. Predicted to contribute to histone acetyltransferase activity. Predicted to be involved in several processes, including regulation of cell division; regulation of embryonic development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including chromatin organization; regulation of protein modification process; and regulation of protein stability. Predicted to be located in mitotic spindle. Predicted to be part of ATAC complex and SAGA complex. Predicted to be active in nucleus. Orthologous to human TADA2A (transcriptional adaptor 2A); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADA2-like protein; LOC360581; Tada2l; transcriptional adapter 2-alpha; transcriptional adapter 2-like; transcriptional adaptor 2 (ADA2 homolog, yeast)-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81069,463,966 - 69,511,612 (-)NCBIGRCr8
mRatBN7.21068,966,502 - 69,014,149 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1068,966,502 - 69,014,105 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1073,586,475 - 73,634,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01073,091,491 - 73,139,094 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01068,555,914 - 68,603,517 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01071,393,701 - 71,441,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1071,393,692 - 71,441,389 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01071,307,409 - 71,354,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,365,950 - 72,413,305 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11072,380,321 - 72,427,675 (-)NCBI
Celera1067,895,248 - 67,942,367 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tada2aRatautism spectrum disorder  ISORGD:13205828554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:21844811|PMID:23044707|PMID:25741868|PMID:27569545
Tada2aRatautistic disorder  ISORGD:13205828554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106|PMID:30208311
Tada2aRatchromosome 17q12 deletion syndrome  ISORGD:13205828554872ClinVar Annotator: match by term: Chromosome 17q12 deletion syndromeClinVarPMID:17924346|PMID:21055719|PMID:24088041|PMID:26633545
Tada2aRathyperphosphatasia with impaired intellectual development syndrome 5  ISORGD:13205828554872ClinVar Annotator: match by term: GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 11ClinVarPMID:12148114|PMID:15068978|PMID:20378641|PMID:20633866|PMID:21540130|PMID:22912587|PMID:24905847|PMID:26123568|PMID:28492532|PMID:31604004|PMID:9398836
Tada2aRatNeurodevelopmental Disorders  ISORGD:13205828554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Tada2aRatschizophrenia  ISORGD:13205828554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106|PMID:30208311

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tada2aRat(-)-epigallocatechin 3-gallate multiple interactionsISORGD:13205826480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TADA2A mRNACTDPMID:22079256
Tada2aRat1,2-dimethylhydrazine increases expressionISORGD:132058364804641,2-Dimethylhydrazine results in increased expression of TADA2A mRNACTDPMID:22206623
Tada2aRat17alpha-ethynylestradiol affects expressionISORGD:13205836480464Ethinyl Estradiol affects the expression of TADA2A mRNACTDPMID:17555576
Tada2aRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13205836480464Tetrachlorodibenzodioxin affects the expression of TADA2A mRNACTDPMID:21570461
Tada2aRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of TADA2A mRNACTDPMID:26232522
Tada2aRat2,6-dinitrotoluene affects expressionEXP 64804642,6-dinitrotoluene affects the expression of TADA2A mRNACTDPMID:21346803
Tada2aRat2-hydroxypropanoic acid decreases expressionISORGD:13205826480464Lactic Acid results in decreased expression of TADA2A mRNACTDPMID:30851411
Tada2aRatacrolein multiple interactionsISORGD:13205826480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...CTDPMID:32699268
Tada2aRatall-trans-retinoic acid decreases expressionISORGD:13205826480464Tretinoin results in decreased expression of TADA2A mRNACTDPMID:33167477
Tada2aRatalpha-pinene multiple interactionsISORGD:13205826480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ...CTDPMID:32699268
Tada2aRatAroclor 1254 decreases expressionISORGD:13205836480464Chlorodiphenyl (54% Chlorine) results in decreased expression of TADA2A mRNACTDPMID:23650126
Tada2aRatbenzo[a]pyrene increases expressionISORGD:13205836480464Benzo(a)pyrene results in increased expression of TADA2A mRNACTDPMID:22228805
Tada2aRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of TADA2A mRNACTDPMID:25181051
Tada2aRatbisphenol A decreases expressionISORGD:13205836480464bisphenol A results in decreased expression of TADA2A mRNACTDPMID:32156529
Tada2aRatbisphenol A affects methylationISORGD:13205836480464bisphenol A affects the methylation of TADA2A promoterCTDPMID:27334623
Tada2aRatbisphenol F decreases expressionISORGD:13205836480464bisphenol F results in decreased expression of TADA2A mRNACTDPMID:38685157
Tada2aRatcadmium dichloride decreases expressionISORGD:13205826480464Cadmium Chloride results in decreased expression of TADA2A mRNACTDPMID:12160620|PMID:38568856
Tada2aRatchlorpyrifos decreases expressionISORGD:13205836480464Chlorpyrifos results in decreased expression of TADA2A mRNACTDPMID:37019170
Tada2aRatchrysene increases expressionISORGD:13205836480464chrysene results in increased expression of TADA2A mRNACTDPMID:26377693
Tada2aRatciguatoxin CTX1B affects expressionISORGD:13205836480464Ciguatoxins affects the expression of TADA2A mRNACTDPMID:18353800

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Biological Process
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Original Reference(s)
Tada2aRatbiological_process  ND 159840712/2014: no relevant rat dataRGD 
Tada2aRatchromatin organization acts_upstream_of_or_withinISORGD:13205831624291MGI:1927664 PMID:20562830RGDPMID:20562830
Tada2aRatchromatin organization acts_upstream_of_or_withinIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatchromatin remodeling involved_inIBAFB:FBgn0037555|FB:FBgn0263738|PANTHER:PTN000271860|PomBase:SPAC14C4.12c|SGD:S000002856|UniProtKB:C8V3C21600115GO_REF:0000033GO_CentralGO_REF:0000033
Tada2aRatmitotic cell cycle acts_upstream_of_or_withinIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatmitotic cell cycle acts_upstream_of_or_withinISORGD:13205831624291 PMID:20562830RGDPMID:20562830
Tada2aRatpositive regulation of DNA-templated transcription involved_inIEAGO:00037131600115GO_REF:0000108GOCGO_REF:0000108
Tada2aRatregulation of cell cycle involved_inIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatregulation of cell cycle involved_inISORGD:13205831624291 PMID:19103755RGDPMID:19103755
Tada2aRatregulation of cell cycle involved_inISORGD:13205821624291 PMID:19103755RGDPMID:19103755
Tada2aRatregulation of cell division involved_inIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatregulation of cell division involved_inISORGD:13205831624291 PMID:20562830RGDPMID:20562830
Tada2aRatregulation of cell division involved_inISORGD:13205821624291 PMID:20562830RGDPMID:20562830
Tada2aRatregulation of DNA-templated transcription involved_inISORGD:13205821624291 PMID:19936620RGDPMID:19936620
Tada2aRatregulation of embryonic development involved_inISORGD:13205831624291 PMID:19103755RGDPMID:19103755
Tada2aRatregulation of embryonic development involved_inIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatregulation of macromolecule metabolic process involved_inIEAARBA:ARBA000277811600115GO_REF:0000117UniProtGO_REF:0000117
Tada2aRatregulation of primary metabolic process involved_inIEAARBA:ARBA000262841600115GO_REF:0000117UniProtGO_REF:0000117
Tada2aRatregulation of protein phosphorylation acts_upstream_of_or_withinISORGD:13205831624291 PMID:20562830RGDPMID:20562830
Tada2aRatregulation of protein stability acts_upstream_of_or_withinIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Object Symbol
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Reference
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Source
Original Reference(s)
Tada2aRatATAC complex part_ofISORGD:13205821624291 PMID:19936620RGDPMID:19936620
Tada2aRatATAC complex part_ofISORGD:13205831624291 PMID:19936620, PMID:20562830RGDPMID:19936620|PMID:20562830
Tada2aRatATAC complex part_ofIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatchromosome located_inIEAUniProtKB-KW:KW-01581600115GO_REF:0000043UniProtGO_REF:0000043
Tada2aRatchromosome located_inIEAUniProtKB-SubCell:SL-04681600115GO_REF:0000044UniProtGO_REF:0000044
Tada2aRatmitotic spindle located_inIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatmitotic spindle located_inISORGD:13205831624291 PMID:20562830RGDPMID:20562830
Tada2aRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Tada2aRatnucleus located_inIEAUniProtKB:Q8CHV6|ensembl:ENSMUSP000000187951600115GO_REF:0000107EnsemblGO_REF:0000107
Tada2aRatnucleus located_inISORGD:13205831624291 PMID:20562830RGDPMID:20562830
Tada2aRatnucleus is_active_inIBAFB:FBgn0037555|FB:FBgn0263738|MGI:2144471|PANTHER:PTN000271860|PomBase:SPAC14C4.12c|PomBase:SPCC1682.13|TAIR:locus:2130609|UniProtKB:Q75LL61600115GO_REF:0000033GO_CentralGO_REF:0000033
Tada2aRatnucleus located_inIEAUniRule:UR0004597631600115GO_REF:0000104UniProtGO_REF:0000104
Tada2aRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Tada2aRatSAGA complex part_ofISORGD:13205821624291 PMID:9674425RGDPMID:9674425
Tada2aRatSAGA-type complex part_ofIEAARBA:ARBA000291111600115GO_REF:0000117UniProtGO_REF:0000117
Tada2aRatSAGA-type complex part_ofIBAFB:FBgn0037555|FB:FBgn0263738|MGI:2144471|MGI:3035274|PANTHER:PTN000271862|PomBase:SPCC24B10.08c|SGD:S000002856|UniProtKB:C8V3C2|UniProtKB:O75478|UniProtKB:Q86TJ21600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function
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Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
Tada2aRatchromatin binding enablesIBAPANTHER:PTN000271860|SGD:S0000028561600115GO_REF:0000033GO_CentralGO_REF:0000033
Tada2aRatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Tada2aRathistone acetyltransferase activity contributes_toISORGD:13205821624291 PMID:9674425RGDPMID:9674425
Tada2aRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Tada2aRatprotein binding enablesISORGD:13205821624291UniProtKB:A0A0S2Z3R2|UniProtKB:A0A0S2Z4A7|UniProtKB:A0A0S2Z4G9|UniProtKB:A0A0S2Z5X4|UniProtKB:O14964|UniProtKB:O60573|UniProtKB:O75431|UniProtKB:O75528|UniProtKB:O95363|UniProtKB:P25800|UniProtKB:P47897|UniProtKB:P52292|UniProtKB:P55081|UniProtKB:P61326|UniProtKB:Q12874|UniProtKB:Q13064|UniProtKB:Q16236|UniProtKB:Q17RB0|UniProtKB:Q2WGJ6|UniProtKB:Q5W150|UniProtKB:Q5W5X9|UniProtKB:Q68DK2-5|UniProtKB:Q6PEW1|UniProtKB:Q8IYX3|UniProtKB:Q8N5M4|UniProtKB:Q8TAU3|UniProtKB:Q8TBZ8|UniProtKB:Q8TD31-3|UniProtKB:Q8TES7-6|UniProtKB:Q8WW24|UniProtKB:Q8WWY3|UniProtKB:Q92830|UniProtKB:Q96A72|UniProtKB:Q96FV9|UniProtKB:Q96GN5|UniProtKB:Q96T49|UniProtKB:Q9BRG1|UniProtKB:Q9H6E4|UniProtKB:Q9NSK0|UniProtKB:Q9NX04|UniProtKB:Q9NY61|UniProtKB:Q9Y4H4 PMID:16189514, PMID:20508642, PMID:20562830, PMID:22644376, PMID:25416956, PMID:25910212, PMID:26871637, PMID:29232376, PMID:32296183, PMID:32911434, PMID:33961781RGDPMID:16189514|PMID:20508642|PMID:20562830|PMID:22644376|PMID:25416956|PMID:25910212|PMID:26871637|PMID:29232376|PMID:32296183|PMID:32911434|PMID:33961781
Tada2aRatprotein binding enablesISORGD:1320582,UniProtKB:O75478-21624291UniProtKB:O14964 PMID:26871637RGDPMID:26871637
Tada2aRattranscription coactivator activity enablesIEAInterPro:IPR0168271600115GO_REF:0000002InterProGO_REF:0000002
Tada2aRattranscription coactivator activity enablesIBAPANTHER:PTN000271860|SGD:S000002856|TAIR:locus:2130609|UniProtKB:Q75LL61600115GO_REF:0000033GO_CentralGO_REF:0000033
Tada2aRatzinc ion binding enablesIEAInterPro:IPR0004331600115GO_REF:0000002InterProGO_REF:0000002
Tada2aRatzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
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RGD Manual Annotations


  
Object Symbol
Species
Term
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Evidence
With
Reference
Notes
Source
Original Reference(s)
Tada2aRatRNA polymerase II transcription initiation pathway  ISORGD:13205829681728 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. ATAC-king the complexity of SAGA during evolution. Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.
PMID:9674425   PMID:12477932   PMID:15489334   PMID:17218081   PMID:20508642   PMID:20562830  



Tada2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81069,463,966 - 69,511,612 (-)NCBIGRCr8
mRatBN7.21068,966,502 - 69,014,149 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1068,966,502 - 69,014,105 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1073,586,475 - 73,634,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01073,091,491 - 73,139,094 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01068,555,914 - 68,603,517 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01071,393,701 - 71,441,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1071,393,692 - 71,441,389 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01071,307,409 - 71,354,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,365,950 - 72,413,305 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11072,380,321 - 72,427,675 (-)NCBI
Celera1067,895,248 - 67,942,367 (-)NCBICelera
Cytogenetic Map10q26NCBI
TADA2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381737,406,886 - 37,479,725 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1737,406,886 - 37,479,725 (+)EnsemblGRCh38hg38GRCh38
GRCh371735,766,977 - 35,839,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361732,841,425 - 32,911,339 (+)NCBINCBI36Build 36hg18NCBI36
Celera1732,589,436 - 32,660,208 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1731,705,328 - 31,774,822 (+)NCBIHuRef
CHM1_11735,798,449 - 35,868,684 (+)NCBICHM1_1
T2T-CHM13v2.01738,397,046 - 38,466,403 (+)NCBIT2T-CHM13v2.0
Tada2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,969,746 - 84,020,466 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1183,969,746 - 84,020,426 (-)EnsemblGRCm39 Ensembl
GRCm381184,078,920 - 84,129,644 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,078,920 - 84,129,600 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,892,422 - 83,943,070 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361183,895,115 - 83,945,763 (-)NCBIMGSCv36mm8
Celera1193,684,540 - 93,738,158 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.29NCBI
Tada2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955451549,028 - 587,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955451548,373 - 599,739 (-)NCBIChiLan1.0ChiLan1.0
TADA2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21927,272,723 - 27,347,127 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11729,156,125 - 29,230,503 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01719,595,055 - 19,670,090 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11719,897,659 - 19,967,926 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1719,897,659 - 19,967,926 (-)Ensemblpanpan1.1panPan2
TADA2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,188,193 - 37,241,605 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl937,188,249 - 37,241,512 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha936,412,780 - 36,466,137 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0937,998,547 - 38,052,436 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl937,998,612 - 38,053,162 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1936,779,751 - 36,833,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0937,067,593 - 37,120,965 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0937,154,265 - 37,207,674 (+)NCBIUU_Cfam_GSD_1.0
Tada2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560236,150,457 - 36,201,375 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936490872,945 - 924,614 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936490873,675 - 924,582 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TADA2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1238,875,250 - 38,928,005 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11238,875,156 - 38,928,011 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21240,496,523 - 40,549,428 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TADA2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11630,303,858 - 30,374,104 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1630,300,532 - 30,374,078 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660771,025,277 - 1,098,948 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tada2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248714,415,409 - 4,469,359 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248714,412,703 - 4,478,275 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Tada2a
200 total Variants

Predicted Target Of
Summary Value
Count of predictions:317
Count of miRNA genes:192
Interacting mature miRNAs:228
Transcripts:ENSRNOT00000003699
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 79 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat

1 to 10 of 79 rows
AU046428  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25142,031,531 - 142,032,108 (+)MAPPERmRatBN7.2
mRatBN7.21068,982,371 - 68,982,576 (+)MAPPERmRatBN7.2
Rnor_6.01071,409,573 - 71,409,777NCBIRnor6.0
Rnor_6.05147,895,949 - 147,896,525NCBIRnor6.0
Rnor_5.05151,623,765 - 151,624,341UniSTSRnor5.0
Rnor_5.01071,323,281 - 71,323,485UniSTSRnor5.0
RGSC_v3.41072,381,818 - 72,382,022UniSTSRGSC3.4
Celera1067,910,754 - 67,910,958UniSTS
Celera5140,504,952 - 140,505,528UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map10q26UniSTS
RH139765  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21068,966,585 - 68,966,785 (+)MAPPERmRatBN7.2
Rnor_6.01071,393,789 - 71,393,988NCBIRnor6.0
Rnor_5.01071,307,497 - 71,307,696UniSTSRnor5.0
RGSC_v3.41072,366,034 - 72,366,233UniSTSRGSC3.4
Cytogenetic Map10q26UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000003699   ⟹   ENSRNOP00000003699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1068,966,502 - 69,014,105 (-)Ensembl
Rnor_6.0 Ensembl1071,393,692 - 71,441,389 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087769   ⟹   ENSRNOP00000071555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1068,966,502 - 69,014,105 (-)Ensembl
Rnor_6.0 Ensembl1071,394,313 - 71,439,540 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119062   ⟹   ENSRNOP00000089252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1068,966,504 - 69,007,134 (-)Ensembl
RefSeq Acc Id: NM_001012141   ⟹   NP_001012141
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,569 (-)NCBI
mRatBN7.21068,966,502 - 69,014,106 (-)NCBI
Rnor_6.01071,393,705 - 71,441,402 (-)NCBI
Rnor_5.01071,307,409 - 71,354,792 (-)NCBI
RGSC_v3.41072,365,950 - 72,413,305 (-)RGD
Celera1067,895,248 - 67,942,367 (-)RGD
Sequence:
RefSeq Acc Id: XM_006247041   ⟹   XP_006247103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,612 (-)NCBI
mRatBN7.21068,966,502 - 69,014,149 (-)NCBI
Rnor_6.01071,393,701 - 71,441,435 (-)NCBI
Rnor_5.01071,307,409 - 71,354,792 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247042   ⟹   XP_006247104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,591 (-)NCBI
mRatBN7.21068,966,502 - 69,014,128 (-)NCBI
Rnor_6.01071,393,701 - 71,441,428 (-)NCBI
Rnor_5.01071,307,409 - 71,354,792 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086362   ⟹   XP_038942290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,551 (-)NCBI
mRatBN7.21068,966,502 - 69,014,007 (-)NCBI
RefSeq Acc Id: XM_039086363   ⟹   XP_038942291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,591 (-)NCBI
mRatBN7.21068,966,502 - 69,014,128 (-)NCBI
RefSeq Acc Id: XM_039086364   ⟹   XP_038942292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,607 (-)NCBI
mRatBN7.21068,966,502 - 69,014,149 (-)NCBI
RefSeq Acc Id: XM_039086365   ⟹   XP_038942293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,501,601 (-)NCBI
mRatBN7.21068,966,502 - 69,004,143 (-)NCBI
RefSeq Acc Id: XM_063269381   ⟹   XP_063125451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,466,935 - 69,511,612 (-)NCBI
RefSeq Acc Id: XM_063269382   ⟹   XP_063125452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,463,966 - 69,511,609 (-)NCBI
1 to 5 of 12 rows
1 to 5 of 12 rows
RefSeq Acc Id: NP_001012141   ⟸   NM_001012141
- UniProtKB: A1EC76 (UniProtKB/Swiss-Prot),   Q6AYE3 (UniProtKB/Swiss-Prot),   A0A8I6ABC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247104   ⟸   XM_006247042
- Peptide Label: isoform X3
- UniProtKB: A0A8L2UHP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247103   ⟸   XM_006247041
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K0R7 (UniProtKB/TrEMBL),   A0A8I6ABC7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071555   ⟸   ENSRNOT00000087769
Ensembl Acc Id: ENSRNOP00000003699   ⟸   ENSRNOT00000003699
HTH myb-type   Myb-like   SANT   SWIRM   ZZ-type

Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYE3-F1-model_v2 AlphaFold Q6AYE3 1-443 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697547
Promoter ID:EPDNEW_R8072
Type:initiation region
Name:Tada2a_1
Description:transcriptional adaptor 2A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01071,441,384 - 71,441,444EPDNEW


1 to 40 of 44 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-23846 BioCyc
Ensembl Genes ENSRNOG00000002757 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000003699 ENTREZGENE
  ENSRNOT00000087769 ENTREZGENE
  ENSRNOT00000119062 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
  3.30.60.90 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7123007 IMAGE-MGC_LOAD
InterPro ADA2-like_ZZ UniProtKB/Swiss-Prot
  Ada2/TADA2 UniProtKB/Swiss-Prot
  Homeobox-like_sf UniProtKB/Swiss-Prot
  Myb_dom UniProtKB/Swiss-Prot
  SANT/Myb UniProtKB/Swiss-Prot
  SANT_dom UniProtKB/Swiss-Prot
  SWIRM UniProtKB/Swiss-Prot
  TADA2A_B-like_dom UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  Znf_ZZ UniProtKB/Swiss-Prot
  Znf_ZZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:360581 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94047 IMAGE-MGC_LOAD
NCBI Gene 360581 ENTREZGENE
PANTHER TRANSCRIPTIONAL ADAPTER 2-ALPHA UniProtKB/Swiss-Prot
  TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED UniProtKB/Swiss-Prot
Pfam Myb_DNA-binding UniProtKB/Swiss-Prot
  SWIRM UniProtKB/Swiss-Prot
  TADA2A-like_3rd UniProtKB/Swiss-Prot
PhenoGen Tada2a PhenoGen
PIRSF Transcriptional_adaptor_2 UniProtKB/Swiss-Prot
PROSITE SANT UniProtKB/Swiss-Prot
  SWIRM UniProtKB/Swiss-Prot
  ZF_ZZ_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002757 RatGTEx
SMART SANT UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF46689 UniProtKB/Swiss-Prot
UniProt A0A0G2K0R7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UHP0 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 44 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Tada2a  transcriptional adaptor 2A  Tada2l  transcriptional adaptor 2 (ADA2 homolog, yeast)-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tada2l  transcriptional adaptor 2 (ADA2 homolog, yeast)-like  Tada2l_predicted  transcriptional adaptor 2 (ADA2 homolog, yeast)-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tada2l_predicted  transcriptional adaptor 2 (ADA2 homolog, yeast)-like (predicted)      Symbol and Name status set to approved 70820 APPROVED