Glrx5 (glutaredoxin 5) - Rat Genome Database

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Gene: Glrx5 (glutaredoxin 5) Rattus norvegicus
Analyze
Symbol: Glrx5
Name: glutaredoxin 5
RGD ID: 1308383
Description: Predicted to enable 2 iron, 2 sulfur cluster binding activity and metal ion binding activity. Predicted to be involved in [2Fe-2S] cluster assembly. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Orthologous to human GLRX5 (glutaredoxin 5); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutaredoxin 5 homolog; glutaredoxin 5 homolog (S. cerevisiae); glutaredoxin-related protein 5, mitochondrial; LOC362776; RGD1308383; similar to 2900070E19Rik protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86129,752,902 - 129,763,278 (+)NCBIGRCr8
mRatBN7.26123,988,461 - 123,998,545 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6123,988,134 - 123,998,545 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6124,118,169 - 124,128,237 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06124,413,421 - 124,423,489 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06123,785,337 - 123,795,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06128,750,503 - 128,760,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6128,750,795 - 128,760,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06137,947,583 - 137,957,960 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46129,233,209 - 129,243,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16129,236,842 - 129,245,795 (+)NCBI
Celera6121,459,083 - 121,469,162 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glrx5Ratautosomal recessive pyridoxine-refractory sideroblastic anemia 3  ISOGLRX5 (Homo sapiens)8554872ClinVar Annotator: match by term: Sideroblastic anemia 3ClinVarPMID:17485548 more ...
Glrx5RatChildhood-Onset Spasticity with Hyperglycinemia  ISOGLRX5 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24334290 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glrx5Ratautosomal recessive pyridoxine-refractory sideroblastic anemia 2  ISOGLRX5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Glrx5Ratsideroblastic anemia  ISOGLRX5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18637800

1 to 20 of 72 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glrx5Rat(1->4)-beta-D-glucan multiple interactionsISOGlrx5 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GLRX5 mRNACTDPMID:36331819
Glrx5Rat1,2-dimethylhydrazine multiple interactionsISOGlrx5 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GLRX5 mRNACTDPMID:22206623
Glrx5Rat17alpha-ethynylestradiol affects expressionISOGlrx5 (Mus musculus)6480464Ethinyl Estradiol affects the expression of GLRX5 mRNACTDPMID:17555576
Glrx5Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of GLRX5 mRNACTDPMID:32145629
Glrx5Rat17beta-estradiol decreases expressionISOGlrx5 (Mus musculus)6480464Estradiol results in decreased expression of GLRX5 mRNACTDPMID:39298647
Glrx5Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGlrx5 (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GLRX5 mRNACTDPMID:16214954
Glrx5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GLRX5 mRNACTDPMID:26232522
Glrx5Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGlrx5 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of GLRX5 mRNACTDPMID:20702594 and PMID:21570461
Glrx5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGlrx5 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of GLRX5 mRNACTDPMID:18796159
Glrx5Rat2,3,7,8-Tetrachlorodibenzofuran affects expressionISOGlrx5 (Mus musculus)64804642 more ...CTDPMID:20702594
Glrx5Rat4,4'-sulfonyldiphenol increases expressionISOGlrx5 (Mus musculus)6480464bisphenol S results in increased expression of GLRX5 mRNACTDPMID:39298647
Glrx5Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of GLRX5 mRNACTDPMID:31881176
Glrx5Rataconitine increases expressionEXP 6480464Aconitine results in increased expression of GLRX5 proteinCTDPMID:33236894
Glrx5Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of GLRX5 mRNACTDPMID:28959563
Glrx5Ratall-trans-retinoic acid decreases expressionISOGLRX5 (Homo sapiens)6480464Tretinoin results in decreased expression of GLRX5 mRNACTDPMID:33167477
Glrx5Rataristolochic acid A increases expressionISOGLRX5 (Homo sapiens)6480464aristolochic acid I results in increased expression of GLRX5 mRNACTDPMID:33212167
Glrx5RatAroclor 1254 increases expressionISOGlrx5 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of GLRX5 mRNACTDPMID:23650126
Glrx5Ratarsenite(3-) multiple interactionsISOGLRX5 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to GLRX5 mRNA]CTDPMID:32406909
Glrx5Ratatrazine decreases expressionISOGLRX5 (Homo sapiens)6480464Atrazine results in decreased expression of GLRX5 mRNACTDPMID:22378314
Glrx5Ratbenzo[a]pyrene increases expressionISOGlrx5 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of GLRX5 mRNACTDPMID:21715664

1 to 20 of 72 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glrx5Rat[2Fe-2S] cluster assembly involved_inISOGLRX5 (Homo sapiens)1624291UniProtKB:Q02784 and PMID:23615440RGDPMID:23615440
Glrx5Rat[2Fe-2S] cluster assembly involved_inIEAUniProtKB:Q86SX6 and ensembl:ENSP000003285701600115GO_REF:0000107EnsemblGO_REF:0000107
Glrx5Ratbiological_process  ND 159840704/16:no relevant rat dataRGD 
Glrx5Ratprotein maturation involved_inIEAUniProtKB:Q86SX6 and ensembl:ENSP000003285701600115GO_REF:0000107EnsemblGO_REF:0000107
Glrx5Ratprotein maturation involved_inISOGLRX5 (Homo sapiens)1624291UniProtKB:Q02784 and PMID:23615440RGDPMID:23615440

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glrx5Ratdendrite  IDA 5133712 RGD 
Glrx5Ratiron-sulfur cluster assembly complex part_ofISOGLRX5 (Homo sapiens)1624291 PMID:27532772RGDPMID:27532772
Glrx5Ratiron-sulfur cluster assembly complex part_ofIEAUniProtKB:Q86SX6 and ensembl:ENSP000003285701600115GO_REF:0000107EnsemblGO_REF:0000107
Glrx5Ratmitochondrial matrix located_inISOGLRX5 (Homo sapiens)1624291 PMID:20364084RGDPMID:20364084
Glrx5Ratmitochondrial matrix is_active_inIBAPANTHER:PTN008497287 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Glrx5Ratmitochondrial matrix located_inIEAUniProtKB:Q86SX6 and ensembl:ENSP000003285701600115GO_REF:0000107EnsemblGO_REF:0000107
Glrx5Ratmitochondrion located_inISOGLRX5 (Homo sapiens)1624291 RGDGO_REF:0000052
Glrx5Ratmitochondrion located_inIEAUniProtKB:Q86SX6 and ensembl:ENSP000003285701600115GO_REF:0000107EnsemblGO_REF:0000107
Glrx5Ratmitochondrion located_inIEAARBA:ARBA000269621600115GO_REF:0000117UniProtGO_REF:0000117
Glrx5Ratmitochondrion located_inIEAUniProtKB:A0A384MDT9 and ensembl:ENSP000003285701600115GO_REF:0000107EnsemblGO_REF:0000107
Glrx5Ratmitochondrion located_inISOGlrx5 (Mus musculus)1624291 PMID:14651853RGDPMID:14651853
Glrx5Ratneuronal cell body  IDA 5133712 RGD 
1 to 12 of 12 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glrx5Ratmitochondrial iron-sulfur cluster protein biogenesis pathway   ISOGLRX5 (Homo sapiens)11554190 RGD 

1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Thioredoxin and glutaredoxin system proteins-immunolocalization in the rat central nervous system. Aon-Bertolino ML, etal., Biochim Biophys Acta. 2011 Jan;1810(1):93-110. Epub 2010 Jul 8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
1 to 9 of 9 rows
PMID:14651853   PMID:18614015   PMID:20364084   PMID:24334290  



Glrx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86129,752,902 - 129,763,278 (+)NCBIGRCr8
mRatBN7.26123,988,461 - 123,998,545 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6123,988,134 - 123,998,545 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6124,118,169 - 124,128,237 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06124,413,421 - 124,423,489 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06123,785,337 - 123,795,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06128,750,503 - 128,760,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6128,750,795 - 128,760,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06137,947,583 - 137,957,960 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46129,233,209 - 129,243,293 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16129,236,842 - 129,245,795 (+)NCBI
Celera6121,459,083 - 121,469,162 (+)NCBICelera
Cytogenetic Map6q32NCBI
GLRX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381495,535,050 - 95,544,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1495,533,503 - 95,544,724 (+)EnsemblGRCh38hg38GRCh38
GRCh371496,001,387 - 96,011,051 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361495,071,076 - 95,080,808 (+)NCBINCBI36Build 36hg18NCBI36
Build 341495,071,075 - 95,080,808NCBI
Celera1476,057,010 - 76,066,743 (+)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1476,186,979 - 76,196,711 (+)NCBIHuRef
CHM1_11495,939,246 - 95,948,981 (+)NCBICHM1_1
T2T-CHM13v2.01489,765,742 - 89,775,402 (+)NCBIT2T-CHM13v2.0
Glrx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912104,998,877 - 105,007,170 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12104,998,947 - 105,009,165 (+)EnsemblGRCm39 Ensembl
GRCm3812105,032,618 - 105,040,911 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12105,032,688 - 105,042,906 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712106,270,899 - 106,279,120 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612105,433,739 - 105,441,960 (+)NCBIMGSCv36mm8
Celera12106,265,134 - 106,273,355 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1255.04NCBI
Glrx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543817,066,955 - 17,075,789 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543817,067,017 - 17,076,162 (-)NCBIChiLan1.0ChiLan1.0
GLRX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21596,688,753 - 96,698,490 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11495,905,267 - 95,914,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01476,162,541 - 76,172,291 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11495,486,818 - 95,496,438 (+)NCBIpanpan1.1PanPan1.1panPan2
GLRX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1864,383,203 - 64,392,886 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl864,383,227 - 64,383,841 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha863,961,948 - 63,972,042 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0864,651,949 - 64,662,047 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl864,652,309 - 64,662,049 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1864,326,648 - 64,336,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0864,385,664 - 64,395,761 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0864,710,831 - 64,720,934 (+)NCBIUU_Cfam_GSD_1.0
GLRX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7116,787,432 - 116,800,554 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17116,787,346 - 116,797,477 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27124,001,745 - 124,011,835 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLRX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12473,387,941 - 73,398,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2473,387,641 - 73,398,233 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605360,564,346 - 60,574,102 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glrx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247347,987,116 - 7,995,220 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247347,986,999 - 7,995,604 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Glrx5
47 total Variants

Predicted Target Of
Summary Value
Count of predictions:220
Count of miRNA genes:147
Interacting mature miRNAs:176
Transcripts:ENSRNOT00000005781
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 26 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat

1 to 10 of 26 rows
RH128046  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26123,996,866 - 123,997,076 (+)MAPPERmRatBN7.2
Rnor_6.06128,759,202 - 128,759,411NCBIRnor6.0
Rnor_5.06137,956,282 - 137,956,491UniSTSRnor5.0
RGSC_v3.46129,241,615 - 129,241,824UniSTSRGSC3.4
Celera6121,467,484 - 121,467,693UniSTS
RH 3.4 Map6820.0UniSTS
Cytogenetic Map6q32UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000005781   ⟹   ENSRNOP00000005781
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6123,988,134 - 123,998,545 (+)Ensembl
Rnor_6.0 Ensembl6128,750,795 - 128,760,880 (+)Ensembl
RefSeq Acc Id: NM_001108722   ⟹   NP_001102192
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86129,753,194 - 129,763,278 (+)NCBI
mRatBN7.26123,988,461 - 123,998,545 (+)NCBI
Rnor_6.06128,750,795 - 128,760,880 (+)NCBI
Rnor_5.06137,947,583 - 137,957,960 (+)NCBI
RGSC_v3.46129,233,209 - 129,243,293 (+)RGD
Celera6121,459,083 - 121,469,162 (+)RGD
Sequence:
RefSeq Acc Id: XM_063262127   ⟹   XP_063118197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86129,752,902 - 129,762,033 (+)NCBI
Protein RefSeqs NP_001102192 (Get FASTA)   NCBI Sequence Viewer  
  NP_001416079 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118197 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81815 (Get FASTA)   NCBI Sequence Viewer  
  EDL81816 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005781
  ENSRNOP00000005781.5
RefSeq Acc Id: NP_001102192   ⟸   NM_001108722
- UniProtKB: A6JES1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005781   ⟸   ENSRNOT00000005781
RefSeq Acc Id: XP_063118197   ⟸   XM_063262127
- Peptide Label: isoform X1
Glutaredoxin

Name Modeler Protein Id AA Range Protein Structure
AF-D4ADD7-F1-model_v2 AlphaFold D4ADD7 1-152 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694809
Promoter ID:EPDNEW_R5334
Type:multiple initiation site
Name:Glrx5_1
Description:glutaredoxin 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06128,750,802 - 128,750,862EPDNEW


1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-36351 BioCyc
Ensembl Genes ENSRNOG00000004206 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005781 ENTREZGENE
  ENSRNOT00000005781.6 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Glutaredoxin UniProtKB/TrEMBL
  GRX_PICOT_like UniProtKB/TrEMBL
  Monothiol_GRX_rel UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
KEGG Report rno:362776 UniProtKB/TrEMBL
NCBI Gene 362776 ENTREZGENE
PANTHER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL UniProtKB/TrEMBL
  Glutredox-rel UniProtKB/TrEMBL
Pfam Glutaredoxin UniProtKB/TrEMBL
PhenoGen Glrx5 PhenoGen
PROSITE GLUTAREDOXIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004206 RatGTEx
Superfamily-SCOP Thiordxn-like_fd UniProtKB/TrEMBL
UniProt A6JES1 ENTREZGENE, UniProtKB/TrEMBL
  D4ADD7_RAT UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-16 Glrx5  glutaredoxin 5  Glrx5  glutaredoxin 5 homolog (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Glrx5  glutaredoxin 5 homolog (S. cerevisiae)   Glrx5_predicted  glutaredoxin 5 homolog (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Glrx5_predicted  glutaredoxin 5 homolog (S. cerevisiae) (predicted)  RGD1308383_predicted  similar to 2900070E19Rik protein (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1308383_predicted  similar to 2900070E19Rik protein (predicted)  LOC362776_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362776_predicted  similar to 2900070E19Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL