Exosc8 (exosome component 8) - Rat Genome Database

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Gene: Exosc8 (exosome component 8) Rattus norvegicus
Analyze
Symbol: Exosc8
Name: exosome component 8
RGD ID: 1306169
Description: Predicted to enable identical protein binding activity and mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in RNA metabolic process. Predicted to be located in chromosome; cytosol; and nuclear lumen. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1C. Orthologous to human EXOSC8 (exosome component 8); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: exosome complex component RRP43; exosome complex exonuclease RRP43; LOC295050
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82141,080,568 - 141,087,112 (-)NCBIGRCr8
mRatBN7.22138,930,405 - 138,937,009 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2138,930,405 - 138,936,928 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2145,504,656 - 145,511,199 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02143,616,682 - 143,623,225 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02138,248,517 - 138,255,060 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02143,925,643 - 143,932,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2143,925,546 - 143,931,940 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02160,331,306 - 160,337,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42143,954,943 - 143,961,239 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12143,905,006 - 143,911,553 (-)NCBI
Celera2133,415,207 - 133,421,503 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exosc8RatMHC class II deficiency  ISOEXOSC8 (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:22390233 more ...
Exosc8Ratpontocerebellar hypoplasia type 1C  ISOEXOSC8 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24989451 more ...
Exosc8Ratspastic ataxia  ISOEXOSC8 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic ataxiaClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exosc8Ratpontocerebellar hypoplasia type 1C  ISOEXOSC8 (Homo sapiens)7240710 OMIM 

1 to 20 of 98 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exosc8Rat(1->4)-beta-D-glucan multiple interactionsISOExosc8 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of EXOSC8 mRNACTDPMID:36331819
Exosc8Rat1,2-dimethylhydrazine multiple interactionsISOExosc8 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EXOSC8 mRNACTDPMID:22206623
Exosc8Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of EXOSC8 mRNACTDPMID:17108234
Exosc8Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOExosc8 (Mus musculus)64804642 more ...CTDPMID:30294300
Exosc8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of EXOSC8 mRNACTDPMID:21215274 and PMID:34747641
Exosc8Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOEXOSC8 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of EXOSC8 mRNACTDPMID:22574217
Exosc8Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOExosc8 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of EXOSC8 mRNACTDPMID:21570461
Exosc8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOEXOSC8 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of EXOSC8 mRNACTDPMID:21632981
Exosc8Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of EXOSC8 mRNACTDPMID:21346803
Exosc8Rat2-methylcholine affects expressionISOEXOSC8 (Homo sapiens)6480464beta-methylcholine affects the expression of EXOSC8 mRNACTDPMID:21179406
Exosc8Rat4,4'-diaminodiphenylmethane increases expressionISOExosc8 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of EXOSC8 mRNACTDPMID:18648102
Exosc8Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of EXOSC8 mRNACTDPMID:36041667
Exosc8Ratacrylamide increases expressionISOEXOSC8 (Homo sapiens)6480464Acrylamide results in increased expression of EXOSC8 mRNACTDPMID:32763439
Exosc8Ratactinomycin D multiple interactionsISOEXOSC8 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of EXOSC8 proteinCTDPMID:38460933
Exosc8Rataflatoxin B1 increases expressionISOExosc8 (Mus musculus)6480464Aflatoxin B1 results in increased expression of EXOSC8 mRNACTDPMID:19770486
Exosc8Ratall-trans-retinoic acid decreases expressionISOEXOSC8 (Homo sapiens)6480464Tretinoin results in decreased expression of EXOSC8 mRNACTDPMID:33167477
Exosc8Ratantimycin A increases expressionISOEXOSC8 (Homo sapiens)6480464Antimycin A results in increased expression of EXOSC8 mRNACTDPMID:33512557
Exosc8Rataristolochic acid A decreases expressionISOEXOSC8 (Homo sapiens)6480464aristolochic acid I results in decreased expression of EXOSC8 mRNACTDPMID:33212167
Exosc8RatAroclor 1254 increases expressionISOExosc8 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of EXOSC8 mRNACTDPMID:25270620
Exosc8Ratarsenite(3-) multiple interactionsISOEXOSC8 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to EXOSC8 mRNA]CTDPMID:32406909

1 to 20 of 98 rows

Biological Process
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exosc8Ratexonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) involved_inIBAPANTHER:PTN000120504 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8Ratnuclear mRNA surveillance involved_inIBAPANTHER:PTN000120504 and UniProtKB:Q062651600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8Ratnuclear polyadenylation-dependent rRNA catabolic process involved_inIBAPANTHER:PTN000120504 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8RatRNA catabolic process involved_inISOEXOSC8 (Homo sapiens)1624291 PMID:17174896 and PMID:20531386RGDPMID:17174896 and PMID:20531386
Exosc8RatRNA catabolic process involved_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8RatRNA catabolic process involved_inIEAInterPro:IPR0331961600115GO_REF:0000002InterProGO_REF:0000002
Exosc8RatRNA processing involved_inIEAInterPro:IPR0331961600115GO_REF:0000002InterProGO_REF:0000002
Exosc8RatRNA processing involved_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8RatRNA processing involved_inISOEXOSC8 (Homo sapiens)1624291 PMID:17174896 and PMID:20531386RGDPMID:17174896 and PMID:20531386
Exosc8RatrRNA catabolic process involved_inIBAPANTHER:PTN000120503 and SGD:S0000022691600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8RatrRNA processing involved_inIEAUniProtKB-KW:KW-06981600115GO_REF:0000043UniProtGO_REF:0000043
Exosc8RatTRAMP-dependent tRNA surveillance pathway involved_inIBAPANTHER:PTN000120504 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8RatU1 snRNA 3'-end processing involved_inIBAPANTHER:PTN000120504 and SGD:S0000026881600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8RatU4 snRNA 3'-end processing involved_inIBAPANTHER:PTN000120504 and SGD:S0000026881600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8RatU5 snRNA 3'-end processing involved_inIBAPANTHER:PTN000120504 and SGD:S0000026881600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 15 of 15 rows

Cellular Component
1 to 20 of 25 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exosc8Ratchromosome located_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8Ratchromosome located_inISOEXOSC8 (Homo sapiens)1624291 RGDGO_REF:0000052
Exosc8Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Exosc8Ratcytoplasm located_inISOEXOSC8 (Homo sapiens)1624291 PMID:17545563RGDPMID:17545563
Exosc8Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Exosc8Ratcytoplasm located_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8Ratcytoplasmic exosome (RNase complex) part_ofIBAPANTHER:PTN000120503 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8Ratcytosol located_inISOEXOSC8 (Homo sapiens)1624291 PMID:20531386RGDGO_REF:0000052 and PMID:20531386
Exosc8Ratcytosol located_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8Ratexosome (RNase complex) part_ofISOEXOSC8 (Homo sapiens)1624291 PMID:20531389RGDPMID:20531389
Exosc8Ratexosome (RNase complex) part_ofIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8Ratexosome (RNase complex) part_ofIEAInterPro:IPR0331961600115GO_REF:0000002InterProGO_REF:0000002
Exosc8Ratexosome (RNase complex) part_ofIEAUniProtKB-KW:KW-02711600115GO_REF:0000043UniProtGO_REF:0000043
Exosc8Ratfibrillar center located_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8Ratfibrillar center located_inISOEXOSC8 (Homo sapiens)1624291 RGDGO_REF:0000052
Exosc8Ratintracellular membrane-bounded organelle located_inISOEXOSC8 (Homo sapiens)1624291 RGDGO_REF:0000052
Exosc8Ratintracellular membrane-bounded organelle located_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
Exosc8Ratnuclear exosome (RNase complex) part_ofIBAFB:FBgn0034065 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Exosc8Ratnucleolus located_inIEAUniProtKB-SubCell:SL-01881600115GO_REF:0000044UniProtGO_REF:0000044
Exosc8Ratnucleolus located_inIEAUniProtKB:Q96B26 and ensembl:ENSP000003743541600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 25 rows

Molecular Function
1 to 9 of 9 rows

  
1 to 9 of 9 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exosc8RatRNA degradation pathway  IEA 6907045 KEGGrno:03018

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15231747   PMID:16912217   PMID:17174896   PMID:17545563   PMID:20531389   PMID:22871113   PMID:25416956  



Exosc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82141,080,568 - 141,087,112 (-)NCBIGRCr8
mRatBN7.22138,930,405 - 138,937,009 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2138,930,405 - 138,936,928 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2145,504,656 - 145,511,199 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02143,616,682 - 143,623,225 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02138,248,517 - 138,255,060 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02143,925,643 - 143,932,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2143,925,546 - 143,931,940 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02160,331,306 - 160,337,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42143,954,943 - 143,961,239 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12143,905,006 - 143,911,553 (-)NCBI
Celera2133,415,207 - 133,421,503 (-)NCBICelera
Cytogenetic Map2q26NCBI
EXOSC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381337,000,786 - 37,009,614 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1336,998,816 - 37,025,881 (+)EnsemblGRCh38hg38GRCh38
GRCh371337,574,923 - 37,583,751 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361336,472,917 - 36,481,538 (+)NCBINCBI36Build 36hg18NCBI36
Build 341336,472,916 - 36,481,533NCBI
Celera1318,641,920 - 18,650,994 (+)NCBICelera
Cytogenetic Map13q13.3NCBI
HuRef1318,386,195 - 18,395,269 (+)NCBIHuRef
CHM1_11337,542,228 - 37,551,301 (+)NCBICHM1_1
T2T-CHM13v2.01336,219,982 - 36,228,811 (+)NCBIT2T-CHM13v2.0
Exosc8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39354,636,099 - 54,642,469 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl354,636,099 - 54,642,814 (-)EnsemblGRCm39 Ensembl
GRCm38354,728,679 - 54,735,364 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl354,728,678 - 54,735,393 (-)EnsemblGRCm38mm10GRCm38
MGSCv37354,532,601 - 54,539,286 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36354,816,609 - 54,823,322 (-)NCBIMGSCv36mm8
Celera354,450,363 - 54,457,048 (-)NCBICelera
Cytogenetic Map3CNCBI
cM Map325.6NCBI
Exosc8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554319,049,896 - 9,058,264 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554319,048,210 - 9,058,079 (-)NCBIChiLan1.0ChiLan1.0
EXOSC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21436,520,654 - 36,529,766 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11327,626,152 - 27,635,938 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01318,208,074 - 18,217,426 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11336,638,238 - 36,647,273 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1336,638,406 - 36,647,273 (+)Ensemblpanpan1.1panPan2
EXOSC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1253,698,399 - 3,708,342 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl253,698,483 - 3,769,683 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha253,728,510 - 3,738,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0253,796,701 - 3,806,631 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl253,796,785 - 3,868,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1253,699,634 - 3,709,602 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0253,690,760 - 3,700,868 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0253,762,772 - 3,772,753 (-)NCBIUU_Cfam_GSD_1.0
Exosc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945164,836,513 - 164,839,471 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647231,112,733 - 31,115,639 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOSC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1112,817,110 - 12,825,843 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11112,817,081 - 12,825,847 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21112,775,507 - 12,784,038 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXOSC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1315,520,122 - 15,529,101 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl315,519,804 - 15,529,014 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605728,755,523 - 28,764,658 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exosc8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624776223,236 - 230,620 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624776223,236 - 230,572 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Exosc8
27 total Variants

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:24
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000017993
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 65 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1549841Bp256Blood pressure QTL 2560.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2137219876142323610Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2102803808147803808Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat

1 to 10 of 65 rows
RH129336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22138,930,450 - 138,930,948 (+)MAPPERmRatBN7.2
mRatBN7.2562,498,224 - 62,498,442 (+)MAPPERmRatBN7.2
Rnor_6.0563,918,395 - 63,918,612NCBIRnor6.0
Rnor_6.02143,925,689 - 143,926,186NCBIRnor6.0
Rnor_5.0568,435,750 - 68,435,967UniSTSRnor5.0
Rnor_5.02160,337,315 - 160,337,812UniSTSRnor5.0
RGSC_v3.42143,954,988 - 143,955,485UniSTSRGSC3.4
RGSC_v3.4564,850,065 - 64,850,282UniSTSRGSC3.4
Celera565,096,714 - 65,096,931UniSTS
Celera2133,415,252 - 133,415,749UniSTS
RH 3.4 Map2860.6UniSTS
Cytogenetic Map2q26UniSTS
Cytogenetic Map5q22UniSTS
AA924460  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2562,498,132 - 62,498,305 (+)MAPPERmRatBN7.2
mRatBN7.22138,930,587 - 138,931,503 (+)MAPPERmRatBN7.2
Rnor_6.02143,925,826 - 143,926,741NCBIRnor6.0
Rnor_6.0563,918,303 - 63,918,475NCBIRnor6.0
Rnor_5.0568,435,658 - 68,435,830UniSTSRnor5.0
Rnor_5.02160,336,760 - 160,337,675UniSTSRnor5.0
RGSC_v3.42143,955,125 - 143,956,040UniSTSRGSC3.4
RGSC_v3.4564,849,973 - 64,850,145UniSTSRGSC3.4
Celera565,096,851 - 65,097,023UniSTS
Celera2133,415,389 - 133,416,304UniSTS
RH 3.4 Map5409.7UniSTS
Cytogenetic Map2q26UniSTS
Cytogenetic Map5q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000081705   ⟹   ENSRNOP00000073348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2138,930,405 - 138,936,928 (-)Ensembl
Rnor_6.0 Ensembl2143,925,546 - 143,931,316 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086214   ⟹   ENSRNOP00000073903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2138,930,406 - 138,936,702 (-)Ensembl
Rnor_6.0 Ensembl2143,925,644 - 143,931,940 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101091   ⟹   ENSRNOP00000088748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2138,930,405 - 138,935,705 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107413   ⟹   ENSRNOP00000093727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2138,930,405 - 138,936,922 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111232   ⟹   ENSRNOP00000097501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2138,930,405 - 138,934,932 (-)Ensembl
RefSeq Acc Id: NM_001399221   ⟹   NP_001386150
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82141,080,568 - 141,087,097 (-)NCBI
mRatBN7.22138,930,405 - 138,936,934 (-)NCBI
RefSeq Acc Id: XM_039102009   ⟹   XP_038957937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82141,081,691 - 141,087,112 (-)NCBI
mRatBN7.22138,931,600 - 138,937,007 (-)NCBI
1 to 12 of 12 rows
Protein RefSeqs NP_001386150 (Get FASTA)   NCBI Sequence Viewer  
  XP_038957937 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM14921 (Get FASTA)   NCBI Sequence Viewer  
  EDM14922 (Get FASTA)   NCBI Sequence Viewer  
  EDM14923 (Get FASTA)   NCBI Sequence Viewer  
  EDM14924 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073348.2
  ENSRNOP00000073903.2
  ENSRNOP00000088748.1
  ENSRNOP00000093727
  ENSRNOP00000093727.1
  ENSRNOP00000097501.1
1 to 12 of 12 rows
Ensembl Acc Id: ENSRNOP00000073348   ⟸   ENSRNOT00000081705
Ensembl Acc Id: ENSRNOP00000073903   ⟸   ENSRNOT00000086214
RefSeq Acc Id: XP_038957937   ⟸   XM_039102009
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000093727   ⟸   ENSRNOT00000107413
Ensembl Acc Id: ENSRNOP00000088748   ⟸   ENSRNOT00000101091
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K5A0-F1-model_v2 AlphaFold A0A0G2K5A0 1-243 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-53076 BioCyc
Ensembl Genes ENSRNOG00000051623 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081705.2 UniProtKB/TrEMBL
  ENSRNOT00000086214.2 UniProtKB/TrEMBL
  ENSRNOT00000101091.1 UniProtKB/TrEMBL
  ENSRNOT00000107413 ENTREZGENE
  ENSRNOT00000107413.1 UniProtKB/TrEMBL
  ENSRNOT00000111232.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.230.70 UniProtKB/TrEMBL
InterPro ExoRNase_PH_dom1 UniProtKB/TrEMBL
  ExoRNase_PH_dom2 UniProtKB/TrEMBL
  ExoRNase_PH_dom2_sf UniProtKB/TrEMBL
  Exosome_comp_Rrp42_subfam UniProtKB/TrEMBL
  PNPase/RNase_PH_dom UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
  Rrp43 UniProtKB/TrEMBL
NCBI Gene 295050 ENTREZGENE
PANTHER EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN UniProtKB/TrEMBL
  PTHR11097:SF9 UniProtKB/TrEMBL
Pfam RNase_PH UniProtKB/TrEMBL
  RNase_PH_C UniProtKB/TrEMBL
PhenoGen Exosc8 PhenoGen
RatGTEx ENSRNOG00000051623 RatGTEx
Superfamily-SCOP 3_ExoRNase UniProtKB/TrEMBL
  SSF54211 UniProtKB/TrEMBL
UniProt A0A0G2K5A0_RAT UniProtKB/TrEMBL
  A0A8I6AAC4_RAT UniProtKB/TrEMBL
  A0A8I6ANH5_RAT UniProtKB/TrEMBL
  A0A8I6AXF8_RAT UniProtKB/TrEMBL
  A6JVC8 ENTREZGENE, UniProtKB/TrEMBL
  D4AE98 ENTREZGENE, UniProtKB/TrEMBL
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Exosc8  exosome component 8   Exosc8_predicted  exosome component 8 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Exosc8_predicted  exosome component 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED