Wdfy1 (WD repeat and FYVE domain containing 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Wdfy1 (WD repeat and FYVE domain containing 1) Rattus norvegicus
Analyze
Symbol: Wdfy1
Name: WD repeat and FYVE domain containing 1
RGD ID: 1305996
Description: Predicted to enable 1-phosphatidylinositol binding activity. Predicted to be involved in positive regulation of toll-like receptor 3 signaling pathway and positive regulation of toll-like receptor 4 signaling pathway. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and nucleolus. Predicted to be active in early endosome. Orthologous to human WDFY1 (WD repeat and FYVE domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC108351959; LOC301549; MGC93914; uncharacterized LOC108351959; WD repeat and FYVE domain-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8988,459,613 - 88,541,215 (-)NCBIGRCr8
mRatBN7.2981,034,852 - 81,092,823 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl981,034,849 - 81,092,775 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx989,464,594 - 89,522,539 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0994,593,490 - 94,651,433 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0992,976,004 - 93,033,955 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0985,477,070 - 85,528,885 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl985,475,841 - 85,528,869 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0985,228,597 - 85,280,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4979,010,150 - 79,059,470 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1979,193,571 - 79,242,889 (-)NCBI
Celera978,532,988 - 78,582,544 (-)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdfy1RatNeurodevelopmental Disorders  ISOWDFY1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868

1 to 20 of 80 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdfy1Rat1,2-dichloroethane decreases expressionISOWdfy1 (Mus musculus)6480464ethylene dichloride results in decreased expression of WDFY1 mRNACTDPMID:28189721 and PMID:28960355
Wdfy1Rat1,2-dimethylhydrazine multiple interactionsISOWdfy1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of WDFY1 mRNACTDPMID:22206623
Wdfy1Rat1,2-dimethylhydrazine decreases expressionISOWdfy1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of WDFY1 mRNACTDPMID:22206623
Wdfy1Rat17beta-estradiol multiple interactionsISOWdfy1 (Mus musculus)6480464[Polyphenols co-treated with Estradiol] results in increased expression of WDFY1 mRNACTDPMID:30077407
Wdfy1Rat17beta-estradiol decreases expressionISOWdfy1 (Mus musculus)6480464Estradiol results in decreased expression of WDFY1 mRNACTDPMID:39298647
Wdfy1Rat17beta-estradiol increases expressionISOWdfy1 (Mus musculus)6480464Estradiol results in increased expression of WDFY1 mRNACTDPMID:30077407
Wdfy1Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOWDFY1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Wdfy1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOWdfy1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of WDFY1 mRNACTDPMID:21570461
Wdfy1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of WDFY1 mRNACTDPMID:34747641
Wdfy1Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOWDFY1 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of WDFY1 proteinCTDPMID:31675489
Wdfy1Rat3,4-methylenedioxymethamphetamine increases expressionISOWdfy1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of WDFY1 mRNACTDPMID:20188158
Wdfy1Rat3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of WDFY1 mRNACTDPMID:30071829
Wdfy1Rat4,4'-diaminodiphenylmethane affects expressionISOWdfy1 (Mus musculus)64804644 and 4'-diaminodiphenylmethane affects the expression of WDFY1 mRNACTDPMID:18648102
Wdfy1Rat4,4'-sulfonyldiphenol decreases expressionISOWdfy1 (Mus musculus)6480464bisphenol S results in decreased expression of WDFY1 mRNACTDPMID:39298647
Wdfy1Ratacrolein multiple interactionsISOWDFY1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of WDFY1 mRNACTDPMID:32845096
Wdfy1Ratacrylamide decreases expressionISOWdfy1 (Mus musculus)6480464Acrylamide results in decreased expression of WDFY1 mRNACTDPMID:35032568
Wdfy1Rataflatoxin B1 increases expressionISOWdfy1 (Mus musculus)6480464Aflatoxin B1 results in increased expression of WDFY1 mRNACTDPMID:19770486
Wdfy1Rataflatoxin B1 increases methylationISOWDFY1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of WDFY1 exon and Aflatoxin B1 results in increased methylation of WDFY1 intronCTDPMID:30157460
Wdfy1RatAflatoxin B2 alpha increases methylationISOWDFY1 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of WDFY1 exonCTDPMID:30157460
Wdfy1Ratarsenite(3-) multiple interactionsISOWDFY1 (Homo sapiens)6480464arsenite inhibits the reaction [G3BP1 protein binds to WDFY1 mRNA]CTDPMID:32406909

1 to 20 of 80 rows

Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdfy1Ratpositive regulation of toll-like receptor 3 signaling pathway involved_inISOWDFY1 (Homo sapiens)1624291 PMID:25736436RGDPMID:25736436
Wdfy1Ratpositive regulation of toll-like receptor 3 signaling pathway involved_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratpositive regulation of toll-like receptor 3 signaling pathway involved_inIEAUniProtKB:E9Q4P1 and ensembl:ENSMUSP000001091401600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratpositive regulation of toll-like receptor 3 signaling pathway involved_inIBAMGI:1916618 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wdfy1Ratpositive regulation of toll-like receptor 3 signaling pathway involved_inISOWdfy1 (Mus musculus)1624291 PMID:25736436RGDPMID:25736436
Wdfy1Ratpositive regulation of toll-like receptor 4 signaling pathway involved_inISOWdfy1 (Mus musculus)1624291 PMID:25736436RGDPMID:25736436
Wdfy1Ratpositive regulation of toll-like receptor 4 signaling pathway involved_inIEAUniProtKB:E9Q4P1 and ensembl:ENSMUSP000001091401600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratpositive regulation of toll-like receptor 4 signaling pathway involved_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratpositive regulation of toll-like receptor 4 signaling pathway involved_inIBAMGI:1916618 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wdfy1Ratpositive regulation of toll-like receptor 4 signaling pathway involved_inISOWDFY1 (Homo sapiens)1624291 PMID:25736436RGDPMID:25736436
1 to 10 of 10 rows

Cellular Component
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdfy1Ratcell junction located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratcell junction located_inISOWDFY1 (Homo sapiens)1624291 RGDGO_REF:0000052
Wdfy1Ratcytosol located_inISOWDFY1 (Homo sapiens)1624291 PMID:11739631RGDPMID:11739631
Wdfy1Ratcytosol located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratearly endosome located_inISOWDFY1 (Homo sapiens)1624291 PMID:11739631 and PMID:25736436RGDPMID:11739631 and PMID:25736436
Wdfy1Ratearly endosome located_inIEAUniProtKB-SubCell:SL-00941600115GO_REF:0000044UniProtGO_REF:0000044
Wdfy1Ratearly endosome located_inIEAUniProtKB:E9Q4P1 and ensembl:ENSMUSP000001091401600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratearly endosome is_active_inIBAMGI:1916618 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Wdfy1Ratearly endosome located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratearly endosome located_inISOWdfy1 (Mus musculus)1624291 PMID:25736436RGDPMID:25736436
Wdfy1Ratendosome located_inIEAUniProtKB-KW:KW-09671600115GO_REF:0000043UniProtGO_REF:0000043
Wdfy1RatGolgi apparatus located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1RatGolgi apparatus located_inISOWDFY1 (Homo sapiens)1624291 RGDGO_REF:0000052
Wdfy1Ratintracellular membrane-bounded organelle located_inISOWDFY1 (Homo sapiens)1624291 RGDGO_REF:0000052
Wdfy1Ratintracellular membrane-bounded organelle located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratnucleolus located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratnucleolus located_inISOWDFY1 (Homo sapiens)1624291 RGDGO_REF:0000052
Wdfy1Ratnucleus located_inISOWDFY1 (Homo sapiens)1624291 PMID:11739631RGDPMID:11739631
Wdfy1Ratnucleus located_inIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 19 of 19 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdfy1Rat1-phosphatidylinositol binding enablesISOWDFY1 (Homo sapiens)1624291 PMID:11739631RGDPMID:11739631
Wdfy1Rat1-phosphatidylinositol binding enablesIEAUniProtKB:Q8IWB7 and ensembl:ENSP000002330551600115GO_REF:0000107EnsemblGO_REF:0000107
Wdfy1Ratmetal ion binding enablesIEAInterPro:IPR0003061600115GO_REF:0000002InterProGO_REF:0000002
Wdfy1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Wdfy1Ratprotein binding enablesISOWdfy1 (Mus musculus)1624291UniProtKB:Q80UF7 more ...RGDPMID:25736436
Wdfy1Ratprotein binding enablesISOWDFY1 (Homo sapiens)1624291UniProtKB:O15455 more ...RGDPMID:25736436 more ...
Wdfy1Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11739631   PMID:12477932   PMID:25736436  



Wdfy1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8988,459,613 - 88,541,215 (-)NCBIGRCr8
mRatBN7.2981,034,852 - 81,092,823 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl981,034,849 - 81,092,775 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx989,464,594 - 89,522,539 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0994,593,490 - 94,651,433 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0992,976,004 - 93,033,955 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0985,477,070 - 85,528,885 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl985,475,841 - 85,528,869 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0985,228,597 - 85,280,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4979,010,150 - 79,059,470 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1979,193,571 - 79,242,889 (-)NCBI
Celera978,532,988 - 78,582,544 (-)NCBICelera
Cytogenetic Map9q34NCBI
WDFY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,875,348 - 223,945,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,855,716 - 223,945,357 (-)EnsemblGRCh38hg38GRCh38
GRCh372224,740,065 - 224,810,052 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362224,448,309 - 224,518,296 (-)NCBINCBI36Build 36hg18NCBI36
Build 342224,565,569 - 224,635,557NCBI
Celera2218,505,977 - 218,575,969 (-)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2216,592,701 - 216,661,805 (-)NCBIHuRef
CHM1_12224,746,548 - 224,816,548 (-)NCBICHM1_1
T2T-CHM13v2.02224,358,556 - 224,428,591 (-)NCBIT2T-CHM13v2.0
Wdfy1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39179,679,979 - 79,753,764 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl179,679,979 - 79,753,860 (-)EnsemblGRCm39 Ensembl
GRCm38179,702,262 - 79,776,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl179,702,262 - 79,776,143 (-)EnsemblGRCm38mm10GRCm38
MGSCv37179,698,837 - 79,758,344 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36179,605,440 - 79,640,756 (-)NCBIMGSCv36mm8
Celera179,790,257 - 79,790,462 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map140.94NCBI
Wdfy1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545310,101,576 - 10,149,710 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545310,101,576 - 10,148,205 (+)NCBIChiLan1.0ChiLan1.0
WDFY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213126,466,931 - 126,564,889 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B126,509,926 - 126,579,858 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B111,121,073 - 111,190,968 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B229,697,353 - 229,767,308 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B229,697,353 - 229,767,308 (-)Ensemblpanpan1.1panPan2
WDFY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13729,544,956 - 29,658,544 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3729,444,082 - 29,677,312 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3730,395,512 - 30,511,040 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03729,584,614 - 29,700,361 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3729,570,379 - 29,700,372 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13729,565,490 - 29,610,275 (-)NCBIUMICH_Zoey_3.1
UMICH_Zoey_3.13729,494,822 - 29,546,540 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03729,429,613 - 29,546,246 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03729,439,312 - 29,557,601 (-)NCBIUU_Cfam_GSD_1.0
LOC101955400
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303179,147,492 - 179,262,826 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365695,575,961 - 5,604,970 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049365695,490,319 - 5,544,250 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365695,574,591 - 5,604,948 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDFY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15125,669,842 - 125,720,158 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115125,674,142 - 125,720,187 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215139,069,876 - 139,081,534 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDFY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110109,815,043 - 109,889,120 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10109,818,422 - 109,889,023 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604089,515,457 - 89,583,083 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdfy1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248231,353,621 - 1,401,160 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248231,353,601 - 1,405,762 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Wdfy1
316 total Variants

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:50
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000063834
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 26 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat

1 to 10 of 26 rows
D9Got93  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2981,049,932 - 81,050,077 (+)MAPPERmRatBN7.2
Rnor_6.0985,486,167 - 85,486,311NCBIRnor6.0
Rnor_5.0985,237,694 - 85,237,838UniSTSRnor5.0
RGSC_v3.4979,016,342 - 79,016,487RGDRGSC3.4
RGSC_v3.4979,016,343 - 79,016,487UniSTSRGSC3.4
RGSC_v3.1979,199,762 - 79,199,906RGD
Celera978,538,758 - 78,538,902UniSTS
RH 3.4 Map9737.3UniSTS
RH 3.4 Map9737.3RGD
RH 2.0 Map9821.4RGD
Cytogenetic Map9q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000063834   ⟹   ENSRNOP00000062993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,056,556 - 81,092,775 (-)Ensembl
Rnor_6.0 Ensembl985,479,996 - 85,528,860 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088963   ⟹   ENSRNOP00000072691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,034,849 - 81,092,775 (-)Ensembl
Rnor_6.0 Ensembl985,475,841 - 85,528,869 (-)Ensembl
RefSeq Acc Id: NM_001393984   ⟹   NP_001380913
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,489,227 - 88,541,186 (-)NCBI
mRatBN7.2981,040,833 - 81,092,794 (-)NCBI
RefSeq Acc Id: NR_172063
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,489,227 - 88,541,186 (-)NCBI
mRatBN7.2981,040,833 - 81,092,794 (-)NCBI
RefSeq Acc Id: NR_172064
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,483,246 - 88,541,186 (-)NCBI
mRatBN7.2981,034,852 - 81,092,794 (-)NCBI
RefSeq Acc Id: XM_063266996   ⟹   XP_063123066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,469,596 - 88,541,215 (-)NCBI
RefSeq Acc Id: XM_063266997   ⟹   XP_063123067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,469,596 - 88,541,215 (-)NCBI
RefSeq Acc Id: XM_063266998   ⟹   XP_063123068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,459,613 - 88,541,215 (-)NCBI
RefSeq Acc Id: XR_010054584
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,459,613 - 88,541,215 (-)NCBI
RefSeq Acc Id: XR_010054585
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,469,596 - 88,541,215 (-)NCBI
RefSeq Acc Id: XR_357088
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8988,493,123 - 88,541,215 (-)NCBI
mRatBN7.2981,040,833 - 81,092,823 (-)NCBI
Rnor_6.0985,477,070 - 85,528,885 (-)NCBI
Rnor_5.0985,228,597 - 85,280,673 (-)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001380913 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123066 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123067 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123068 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85807 (Get FASTA)   NCBI Sequence Viewer  
  EDL75485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000062993.2
  ENSRNOP00000072691
  ENSRNOP00000072691.1
1 to 9 of 9 rows
Ensembl Acc Id: ENSRNOP00000062993   ⟸   ENSRNOT00000063834
Ensembl Acc Id: ENSRNOP00000072691   ⟸   ENSRNOT00000088963
RefSeq Acc Id: NP_001380913   ⟸   NM_001393984
- UniProtKB: A0A0G2K3L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123068   ⟸   XM_063266998
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K3L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123067   ⟸   XM_063266997
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K3L8 (UniProtKB/TrEMBL)
FYVE-type

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K3L8-F1-model_v2 AlphaFold A0A0G2K3L8 1-410 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696792
Promoter ID:EPDNEW_R7316
Type:initiation region
Name:Wdfy1_1
Description:WD repeat and FYVE domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0985,528,830 - 85,528,890EPDNEW


1 to 40 of 40 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-27010 BioCyc
Ensembl Genes ENSRNOG00000015080 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000063834.2 UniProtKB/TrEMBL
  ENSRNOT00000088963 ENTREZGENE
  ENSRNOT00000088963.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7112886 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  WDFY1/WDFY2 UniProtKB/TrEMBL
  WDFY1_FYVE UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
MGC_CLONE MGC:93914 IMAGE-MGC_LOAD
NCBI Gene 301549 ENTREZGENE
PANTHER PTHR46189 UniProtKB/TrEMBL
  WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Wdfy1 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015080 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A0G2K3L8 ENTREZGENE, UniProtKB/TrEMBL
  A6JW77_RAT UniProtKB/TrEMBL
  F7ENZ0_RAT UniProtKB/TrEMBL
  Q5U2Y7_RAT UniProtKB/TrEMBL
1 to 40 of 40 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Wdfy1  WD repeat and FYVE domain containing 1  LOC108351959  uncharacterized LOC108351959  Data merged from RGD:11424453 737654 PROVISIONAL
2016-08-02 LOC108351959  uncharacterized LOC108351959      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Wdfy1  WD repeat and FYVE domain containing 1  Wdfy1_predicted  WD repeat and FYVE domain containing 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Wdfy1_predicted  WD repeat and FYVE domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED