Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of WDFY1 mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of WDFY1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of WDFY1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of WDFY1 mRNA | CTD | PMID:30077407 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Polyphenols co-treated with Estradiol] results in increased expression of WDFY1 mRNA | CTD | PMID:30077407 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of WDFY1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of WDFY1 mRNA | CTD | PMID:34747641 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of WDFY1 protein | CTD | PMID:31675489 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of WDFY1 mRNA | CTD | PMID:20188158 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of WDFY1 mRNA | CTD | PMID:30071829 | 4,4'-diaminodiphenylmethane | affects expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of WDFY1 mRNA | CTD | PMID:18648102 | acrolein | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of WDFY1 mRNA | CTD | PMID:32845096 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of WDFY1 mRNA | CTD | PMID:35032568 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of WDFY1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | ISO | WDFY1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of WDFY1 exon and Aflatoxin B1 results in increased methylation of WDFY1 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | WDFY1 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of WDFY1 exon | CTD | PMID:30157460 | arsenite(3-) | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to WDFY1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases methylation | ISO | WDFY1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of WDFY1 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | WDFY1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of WDFY1 exon | CTD | PMID:30157460 | bisphenol A | increases expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of WDFY1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of WDFY1 protein | CTD | PMID:31675489 | bisphenol A | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of WDFY1 mRNA | CTD | PMID:29275510 | Bisphenol B | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of WDFY1 protein | CTD | PMID:34186270 | cadmium atom | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of WDFY1 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of WDFY1 mRNA | CTD | PMID:35301059 | caffeine | increases phosphorylation | ISO | WDFY1 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of WDFY1 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | chloroprene | increases expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | Chloroprene results in increased expression of WDFY1 mRNA | CTD | PMID:23125180 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of WDFY1 mRNA | CTD | PMID:20938992 | cyclosporin A | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of WDFY1 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of WDFY1 protein | CTD | PMID:31675489 | disodium selenite | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of WDFY1 mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of WDFY1 mRNA | CTD | PMID:29803840 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of WDFY1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of WDFY1 mRNA | CTD | PMID:23649840 | fipronil | increases expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of WDFY1 mRNA | CTD | PMID:34044035 | folic acid | multiple interactions | EXP | | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | formaldehyde | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of WDFY1 mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | WDFY1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of WDFY1 protein | CTD | PMID:37730182 | gentamycin | increases expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of WDFY1 mRNA | CTD | PMID:33387578 | irinotecan | affects expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | Irinotecan affects the expression of WDFY1 mRNA | CTD | PMID:20097248 | ivermectin | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of WDFY1 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of WDFY1 mRNA | CTD | PMID:20938992 | methapyrilene | increases methylation | ISO | WDFY1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of WDFY1 exon | CTD | PMID:30157460 | methyl methanesulfonate | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of WDFY1 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of WDFY1 mRNA | CTD | PMID:28001369 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of WDFY1 mRNA and IL10 gene mutant form promotes the reaction [Ozone results in increased expression of WDFY1 mRNA] | CTD | PMID:20826374 and PMID:34911549 | ozone | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of WDFY1 mRNA | CTD | PMID:32845096 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of WDFY1 mRNA | CTD | PMID:20826374 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of WDFY1 mRNA | CTD | PMID:17562736 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of WDFY1 mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of WDFY1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of WDFY1 mRNA | CTD | PMID:27188386 | poly(vinylpyrrolidone) | multiple interactions | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA | CTD | PMID:25194297 | protein kinase inhibitor | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of WDFY1 mRNA] | CTD | PMID:28003376 | quercetin | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of WDFY1 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of WDFY1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | multiple interactions | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA | CTD | PMID:25194297 | silver(0) | multiple interactions | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA | CTD | PMID:25194297 | sodium arsenite | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of WDFY1 mRNA | CTD | PMID:25879800 | sunitinib | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of WDFY1 mRNA | CTD | PMID:31533062 | trichostatin A | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of WDFY1 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of WDFY1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of WDFY1 mRNA | CTD | PMID:19101580 | valproic acid | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of WDFY1 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of WDFY1 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | WDFY1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of WDFY1 mRNA | CTD | PMID:25979313 | venlafaxine hydrochloride | increases expression | ISO | Wdfy1 (Rattus norvegicus) | 6480464 | Venlafaxine Hydrochloride results in increased expression of WDFY1 mRNA | CTD | PMID:25423262 | vorinostat | multiple interactions | ISO | WDFY1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of WDFY1 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | WDFY1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of WDFY1 mRNA | CTD | PMID:26272509 and PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:10349636 | PMID:10512203 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:11544199 | PMID:11700028 | PMID:12466851 | PMID:12477932 | PMID:12520002 | PMID:15782199 |
| PMID:15840001 | PMID:16141072 | PMID:16141073 | PMID:16465591 | PMID:17673451 | PMID:18799693 | PMID:18973680 | PMID:19228596 | PMID:21267068 | PMID:21873635 | PMID:23604909 | PMID:25736436 |
| PMID:28106071 | PMID:30097850 | PMID:31015298 | PMID:32398807 | PMID:33127972 | PMID:33378226 | PMID:34137816 | PMID:34161765 | PMID:35011620 | PMID:35121371 | PMID:36241655 | PMID:38355793 |
Genomics
Comparative Map Data
| Wdfy1 (Mus musculus - house mouse) |
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| WDFY1 (Homo sapiens - human) |
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| Wdfy1 (Rattus norvegicus - Norway rat) |
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| Wdfy1 (Chinchilla lanigera - long-tailed chinchilla) |
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| WDFY1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| WDFY1 (Canis lupus familiaris - dog) |
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| LOC101955400 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| WDFY1 (Sus scrofa - pig) |
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| WDFY1 (Chlorocebus sabaeus - green monkey) |
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| Wdfy1 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Wdfy1
2362 total Variants 
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