Mdh1 (malate dehydrogenase 1) - Rat Genome Database

Mdh1 (malate dehydrogenase 1) - Rat Genome Database

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Gene: Mdh1 (malate dehydrogenase 1) Chinchilla lanigera

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Symbol:

Mdh1

Name:

malate dehydrogenase 1

RGD ID:

8992554

Description:

ENCODES a protein that exhibits L-malate dehydrogenase (NAD+) activity (ortholog); malate dehydrogenase activity (ortholog); NAD binding (ortholog); INVOLVED IN malate metabolic process (ortholog); malate-aspartate shuttle (ortholog); NAD+ metabolic process (ortholog); PARTICIPATES IN Leigh disease pathway; nicotinamide adenine dinucleotide metabolic pathway; primary hyperoxaluria type 2 pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); adult respiratory distress syndrome (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

Previously known as:

malate dehydrogenase 1, NAD (soluble); malate dehydrogenase, cytoplasmic

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MDH1 (malate dehydrogenase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Mdh1 (malate dehydrogenase 1, NAD (soluble))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Mdh1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MDH1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MDH1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mdh1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MDH1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MDH1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mdh1 (malate dehydrogenase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	20,706,058 - 20,723,493 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	20,707,765 - 20,723,493 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	Liver Injury	treatment	ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:24919044 and REF_RGD_ID:13703104

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	Bardet-Biedl syndrome		ISO	MDH1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Bardet-Biedl syndrome	ClinVar	PMID:28492532
Mdh1	Chinchilla	developmental and epileptic encephalopathy 88		ISO	MDH1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 88	ClinVar	PMID:31538237

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	Acute Liver Failure		ISO	MDH1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:35172013
Mdh1	Chinchilla	adult respiratory distress syndrome		ISO	MDH1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25070658
Mdh1	Chinchilla	Chemical and Drug Induced Liver Injury		ISO	MDH1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16099942
Mdh1	Chinchilla	Experimental Liver Cirrhosis		ISO	MDH1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25380136
Mdh1	Chinchilla	hypertension		ISO	MDH1 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22228705

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	developmental and epileptic encephalopathy 88		ISO	MDH1 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	malate metabolic process		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:12351438 more ...
Mdh1	Chinchilla	malate-aspartate shuttle	involved_in	ISO	MDH1 (Homo sapiens)	9068941	PMID:37647199	FlyBase	PMID:37647199
Mdh1	Chinchilla	malate-aspartate shuttle	involved_in	ISO	Mdh1 (Mus musculus)	9068941	PMID:32396938	MGI	PMID:32396938
Mdh1	Chinchilla	NAD+ metabolic process		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:17447164 and REF_RGD_ID:1624966
Mdh1	Chinchilla	NADH metabolic process		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:12351438 and REF_RGD_ID:2303499
Mdh1	Chinchilla	NADH metabolic process	involved_in	ISO	MDH1 (Homo sapiens)	9068941	PMID:34547241	ComplexPortal	PMID:34547241
Mdh1	Chinchilla	NADP+ metabolic process	involved_in	ISO	MDH1 (Homo sapiens)	9068941	PMID:34547241	ComplexPortal	PMID:34547241
Mdh1	Chinchilla	oxaloacetate metabolic process		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:17447164 and REF_RGD_ID:1624966

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	centrosome	located_in	ISO	MDH1 (Homo sapiens)	9068941		HPA	GO_REF:0000052
Mdh1	Chinchilla	cytoplasm	located_in	ISO	MDH1 (Homo sapiens)	9068941	PMID:34547241	ComplexPortal	PMID:34547241
Mdh1	Chinchilla	cytosol	located_in	ISO	MDH1 (Sus scrofa)	9068941	PMID:3312200	MGI	PMID:3312200
Mdh1	Chinchilla	cytosol	is_active_in	ISO	Mdh1 (Mus musculus)	9068941	PMID:5770240	MGI	PMID:5770240
Mdh1	Chinchilla	cytosol	located_in	ISO	MDH1 (Homo sapiens)	9068941		HPA	GO_REF:0000052

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	L-malate dehydrogenase (NAD+) activity	enables	ISO	MGI:1933639	9068941	PMID:7698769	MGI	PMID:7698769
Mdh1	Chinchilla	L-malate dehydrogenase (NAD+) activity	enables	ISO	MDH1 (Homo sapiens)	9068941	PMID:3052244	Reactome	PMID:3052244
Mdh1	Chinchilla	L-malate dehydrogenase (NAD+) activity		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:12351438 more ...
Mdh1	Chinchilla	L-malate dehydrogenase (NAD+) activity	enables	ISO	Mdh1 (Mus musculus)	9068941	PMID:5770240	MGI	PMID:5770240
Mdh1	Chinchilla	malate dehydrogenase activity		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:2820961 and REF_RGD_ID:724435
Mdh1	Chinchilla	NAD binding		ISO	Mdh1 (Rattus norvegicus)	9068941		RGD	PMID:17447164 and REF_RGD_ID:1624966
Mdh1	Chinchilla	NAD binding	enables	ISO	MDH1 (Sus scrofa)	9068941	PMID:10075524	UniProt	PMID:10075524
Mdh1	Chinchilla	protein binding	enables	ISO	UniProtKB:P54274	9068941	PMID:21044950	IntAct	PMID:21044950

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	nicotinamide adenine dinucleotide metabolic pathway		ISO	MDH1 (Homo sapiens)	9068941		RGD	PMID:16368075 more ...

Imported Annotations - SMPDB

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Mdh1	Chinchilla	Leigh disease pathway		ISO	MDH1 (Homo sapiens)	9068941		SMPDB	SMP:00196
Mdh1	Chinchilla	primary hyperoxaluria type 2 pathway		ISO	MDH1 (Homo sapiens)	9068941		SMPDB	SMP:00558
Mdh1	Chinchilla	pyruvate decarboxylase deficiency pathway		ISO	MDH1 (Homo sapiens)	9068941		SMPDB	SMP:00212
Mdh1	Chinchilla	pyruvate dehydrogenase E1 deficiency pathway		ISO	MDH1 (Homo sapiens)	9068941		SMPDB	SMP:00334
Mdh1	Chinchilla	pyruvate kinase deficiency of red cells pathway		ISO	MDH1 (Homo sapiens)	9068941		SMPDB	SMP:00559
Mdh1	Chinchilla	pyruvate metabolic pathway		ISO	MDH1 (Homo sapiens)	9068941		SMPDB	SMP:00060

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

PMID:22301074	PMID:30032202

Mdh1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	20,706,058 - 20,723,493 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	20,707,765 - 20,723,493 (-)	NCBI	ChiLan1.0	ChiLan1.0

MDH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	63,588,963 - 63,607,197 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	63,588,609 - 63,607,197 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	63,816,097 - 63,834,331 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	63,669,626 - 63,687,832 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	63,727,772 - 63,745,979	NCBI
Celera	2	63,661,163 - 63,679,336 (+)	NCBI		Celera
Cytogenetic Map	2	p15	NCBI
HuRef	2	63,556,773 - 63,575,326 (+)	NCBI		HuRef
CHM1_1	2	63,745,880 - 63,764,431 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	63,596,617 - 63,614,818 (+)	NCBI		T2T-CHM13v2.0

Mdh1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	21,506,692 - 21,521,934 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	21,506,692 - 21,522,367 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	21,556,692 - 21,571,934 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	21,556,692 - 21,572,367 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	21,456,695 - 21,471,937 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	21,456,790 - 21,471,832 (-)	NCBI		MGSCv36	mm8
Celera	11	23,704,959 - 23,720,201 (-)	NCBI		Celera
Cytogenetic Map	11	A3.1	NCBI
cM Map	11	13.89	NCBI

Mdh1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	99,831,934 - 99,847,227 (-)	NCBI		GRCr8
mRatBN7.2	14	95,630,625 - 95,645,920 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	95,630,306 - 95,645,925 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	99,982,791 - 99,997,990 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	101,223,133 - 101,238,332 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	97,696,668 - 97,711,868 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	106,378,349 - 106,393,642 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	106,378,942 - 106,393,670 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	106,449,337 - 106,463,995 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	102,259,130 - 102,273,788 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	102,278,343 - 102,292,999 (-)	NCBI
Celera	14	94,639,971 - 94,655,156 (-)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

MDH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	62,789,858 - 62,808,152 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	62,793,808 - 62,812,102 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	63,658,933 - 63,677,257 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	64,785,132 - 64,803,631 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	64,785,132 - 64,803,631 (+)	Ensembl	panpan1.1		panPan2

MDH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	63,316,818 - 63,334,556 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	63,316,831 - 63,361,735 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	63,205,783 - 63,223,532 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	64,325,732 - 64,343,477 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	64,325,748 - 64,393,190 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	64,008,394 - 64,026,100 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	64,316,618 - 64,334,341 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	64,609,207 - 64,626,872 (+)	NCBI		UU_Cfam_GSD_1.0

Mdh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	19,984,379 - 20,000,470 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	8,570,472 - 8,587,686 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	8,570,472 - 8,586,914 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MDH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	78,244,999 - 78,268,600 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	78,247,229 - 78,263,085 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	82,274,663 - 82,280,460 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MDH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	43,406,502 - 43,425,525 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	43,406,499 - 43,425,095 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	68,435,625 - 68,454,293 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mdh1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624762	9,881,950 - 9,901,372 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624762	9,884,521 - 9,900,593 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005385722	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01024871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01083943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000011465 ⟹ ENSCLAP00000011328

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955424	20,706,058 - 20,723,493 (-)	Ensembl

RefSeq Acc Id:

XM_005385722 ⟹ XP_005385779

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955424	20,707,765 - 20,723,493 (-)	NCBI

Sequence:

show sequence

GACTAGCCTTTTCTGACTGTCACAGCGCGCCCTCCTCGACTCGGTTCCGAGCTAGAGGTGACCTGACTTTTCGAGGCTCGCTTTGCAGGTGCAGAAATTGTCCGCGCAGTTCCCAGGCATGTCTGAGC
CAATCAGAGTCCTTGTGACTGGAGCAGCTGGTCAAATTGCATATTCACTGTTGTACAGCATTGGAAATGGGTCTGTCTTTGGTAAAGACCAGCCTATCACTCTTGTGCTATTAGATATCACTCCCATG
ATGGGTGTACTGGACGGGGTCCTCATGGAACTGCAGGACTGTGCCCTTCCCCTCCTGAAAGATGTTATTGCGACAGATAAAGAAGAAGTTGCCTTCAAAGACCTGGATGTGGCTGTTCTCGTGGGCTC
CATGCCGAGAAGGGAAGGCATGGAGAGGAAAGATTTACTGAAAGCAAATGTAAAAATCTTCAAAAGCCAGGGTGCAGCCTTGGATAAATATGCCAAAAAGTCAGTTAAGGTCATCGTTGTGGGAAATC
CAGCGAATACCAACTGCCTGACTGCCTCTAAGTCAGCTCCATCCATCCCGAAGGAGAATTTCAGTTGCCTGACTCGTTTGGACCACAACAGAGCTAAATCTCAAATTGCTCTTAAACTTGGAGTAACT
GCTGATGATGTAAAGAATGTCATCATCTGGGGAAACCATTCCTCAACTCAATATCCAGATGTCAACCATGCCAAGGTGAAATTGCATGGGAAGGAAGTTGGTGTTTATGAAGCTCTGAAAGATGACAG
TTGGCTCAAGGGAGACTTCATCACGATCGTGCAGCAGCGTGGTGCGGCTGTCATCAAAGCTCGGAAACTATCCAGTGCGATGTCTGCTGCAAAAGCCATTGGAGACCACATCAGAAACATCTGGTTTG
GAACCCCAGAGGGAGAGTTCGTGTCCATGGGCGTCTTTTCTGATGGCAACTCCTATGGTATTCCTGATGATCTACTCTATTCATTCCCTGTTGTAATCCAGAATAAGACCTGGAAGTTTGTTGAAGGT
CTCCCTATTAATGATTTCTCACGTGAGAAGATGGATCTTACTGCAAAGGAACTGGCAGAAGAAAAAGAAACTGCTTTTGAATTTCTTTCCTCAGCATGACTAGGCAGTCATTTTGATGTTATTAAATG
CCCCAAAGCTGAAGAATCTAAATGTCGTCTTTGACTCTAGTACCAAATGATGCTATACGTAAAATTACTTGTGAAAAGCAACACATTTTGAAGATTGTGTGCTGCTTGGTACACACTTGTGAGTAAAA
ATCTATCATCATGCTGTTAGTGCTGTATTCTAAATAAAATATATTCAAGTGAATGTGA

hide sequence


Protein RefSeqs	XP_005385779	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000011328
	ENSCLAP00000011328.1

RefSeq Acc Id:

XP_005385779 ⟸ XM_005385722

- UniProtKB:

A0A8C2YNC5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPITLVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEEVAFKDLDVAVLVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIV
VGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVIIWGNHSSTQYPDVNHAKVKLHGKEVGVYEALKDDSWLKGDFITIVQQRGAAVIKARKLSSAMSAAKAIGDHIRN
IWFGTPEGEFVSMGVFSDGNSYGIPDDLLYSFPVVIQNKTWKFVEGLPINDFSREKMDLTAKELAEEKETAFEFLSSA

hide sequence

Ensembl Acc Id:

ENSCLAP00000011328 ⟸ ENSCLAT00000011465

Protein Domains

Lactate/malate dehydrogenase C-terminal Lactate/malate dehydrogenase N-terminal

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000007815	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000011465	ENTREZGENE
	ENSCLAT00000011465.1	UniProtKB/TrEMBL
Gene3D-CATH	3.90.110.10	UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	L-lactate/malate_DH	UniProtKB/TrEMBL
	Lactate/malate_DH_C	UniProtKB/TrEMBL
	Lactate/malate_DH_N	UniProtKB/TrEMBL
	Lactate_DH/Glyco_Ohase_4_C	UniProtKB/TrEMBL
	Malate_DH_AS	UniProtKB/TrEMBL
	Malate_DH_NAD-dep_euk	UniProtKB/TrEMBL
	Malate_DH_type2	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Mdh1	ENTREZGENE
PANTHER	PTHR23382	UniProtKB/TrEMBL
Pfam	Ldh_1_C	UniProtKB/TrEMBL
	Ldh_1_N	UniProtKB/TrEMBL
PIRSF	Lac_mal_DH	UniProtKB/TrEMBL
PROSITE	MDH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51735	UniProtKB/TrEMBL
	SSF56327	UniProtKB/TrEMBL
UniProt	A0A8C2YNC5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Mdh1	malate dehydrogenase 1		malate dehydrogenase 1, NAD (soluble)	Symbol and/or name change	5135510	APPROVED