Pld1 (phospholipase D1) - Rat Genome Database

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Pathways
Gene: Pld1 (phospholipase D1) Chinchilla lanigera
Analyze
Symbol: Pld1
Name: phospholipase D1
RGD ID: 8921146
Description: ENCODES a protein that exhibits D-type glycerophospholipase activity (ortholog); INVOLVED IN cellular response to nutrient (ortholog); defense response to Gram-positive bacterium (ortholog); phosphatidic acid biosynthetic process (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Breast Cancer, Familial (ortholog); Cardiomegaly (ortholog); FOUND IN apical plasma membrane (ortholog); cholinergic synapse (ortholog); endocytic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phospholipase D1, phosphatidylcholine-specific
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554201,696,751 - 1,892,741 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554201,697,716 - 1,892,741 (-)NCBIChiLan1.0ChiLan1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pld1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554201,696,751 - 1,892,741 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554201,697,716 - 1,892,741 (-)NCBIChiLan1.0ChiLan1.0
PLD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383171,600,404 - 171,810,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3171,599,049 - 171,810,950 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh373171,318,194 - 171,528,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363172,801,339 - 172,938,566 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343172,801,346 - 172,938,574NCBI
Celera3169,718,435 - 169,928,143 (-)NCBICelera
Cytogenetic Map3q26.31NCBI
HuRef3168,688,221 - 168,898,341 (-)NCBIHuRef
CHM1_13171,281,084 - 171,491,135 (-)NCBICHM1_1
T2T-CHM13v2.03174,384,521 - 174,594,617 (-)NCBIT2T-CHM13v2.0
Pld1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39327,992,636 - 28,187,388 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl327,992,788 - 28,188,692 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38327,938,459 - 28,133,362 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl327,938,695 - 28,133,362 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37327,837,602 - 28,032,284 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36328,215,231 - 28,324,307 (+)NCBIMGSCv36mm8
Celera327,897,052 - 28,088,894 (+)NCBICelera
Cytogenetic Map3A3NCBI
cM Map311.15NCBI
Pld1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82112,777,820 - 112,975,857 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2112,777,951 - 112,976,245 (+)EnsemblGRCr8
mRatBN7.22110,849,205 - 111,047,304 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2110,893,608 - 111,047,692 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2117,548,080 - 117,700,325 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02115,660,662 - 115,812,852 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02110,374,318 - 110,526,587 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2112,178,223 - 112,333,624 (+)NCBI
Lyon_Normotensive2112,237,121 - 112,392,529 (+)NCBI
Lyon_Hypertensive2112,101,890 - 112,257,307 (+)NCBI
F344_StmMcwi2111,908,768 - 112,064,085 (+)NCBI
Rnor_6.02113,651,967 - 113,849,403 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2113,652,348 - 113,849,403 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.02133,357,235 - 133,554,180 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42115,306,940 - 115,460,518 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2106,084,707 - 106,238,116 (+)NCBICelera
RGSC_v3.12115,251,901 - 115,405,480 (+)NCBI
Cytogenetic Map2q24NCBI
PLD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,481,152 - 169,693,135 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13169,482,578 - 169,696,377 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03168,606,342 - 168,816,383 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13176,790,736 - 176,999,974 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3176,790,753 - 176,961,033 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
PLD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13435,917,759 - 36,080,383 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3435,921,058 - 36,121,631 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3444,928,877 - 45,133,990 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03436,000,267 - 36,205,332 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3436,000,274 - 36,205,751 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13435,940,863 - 36,145,600 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03435,903,822 - 36,109,331 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03436,165,953 - 36,370,780 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pld1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap13116,354,011 - 116,559,195 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_024405602102,572,478 - 102,777,840 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936593930,637 - 1,046,821 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936593844,634 - 1,049,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13110,154,874 - 110,376,294 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.113110,152,268 - 110,376,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213119,138,285 - 119,362,303 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap11517,992,949 - 18,204,963 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366606326,423,171 - 26,629,555 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.11517,667,079 - 17,871,452 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1517,706,030 - 17,870,266 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Pld1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473049,665,432 - 49,885,242 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_00462473049,665,432 - 49,885,184 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl871,973,690 - 72,192,185 (+)Ensembl
Pld1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13126,531,701 - 126,733,956 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005382998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005382999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005383000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005383002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01020576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01020577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01020578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01020579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01020580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01020581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01020582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDI01326771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCLAT00000018288   ⟹   ENSCLAP00000018110
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554201,696,751 - 1,892,741 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000018289   ⟹   ENSCLAP00000018111
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554201,696,751 - 1,859,736 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000018290   ⟹   ENSCLAP00000018112
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554201,696,751 - 1,859,736 (-)Ensembl
RefSeq Acc Id: XM_005382998   ⟹   XP_005383055
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,892,741 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382999   ⟹   XP_005383056
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,859,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383000   ⟹   XP_005383057
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,865,066 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383002   ⟹   XP_005383059
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,892,741 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513558   ⟹   XP_013369012
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,871,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513559   ⟹   XP_013369013
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,892,741 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513560   ⟹   XP_013369014
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,887,676 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513561   ⟹   XP_013369015
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554201,697,716 - 1,871,430 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005383059   ⟸   XM_005383002
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YRK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383055   ⟸   XM_005382998
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VN51 (UniProtKB/TrEMBL),   A0A8C2VN91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383057   ⟸   XM_005383000
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VN51 (UniProtKB/TrEMBL),   A0A8C2VN91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383056   ⟸   XM_005382999
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VN51 (UniProtKB/TrEMBL),   A0A8C2VN91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369013   ⟸   XM_013513559
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VN51 (UniProtKB/TrEMBL),   A0A8C2VN91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369014   ⟸   XM_013513560
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VN51 (UniProtKB/TrEMBL),   A0A8C2VN91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369015   ⟸   XM_013513561
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YRK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369012   ⟸   XM_013513558
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VN51 (UniProtKB/TrEMBL),   A0A8C2VN91 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000018111   ⟸   ENSCLAT00000018289
Ensembl Acc Id: ENSCLAP00000018110   ⟸   ENSCLAT00000018288
Ensembl Acc Id: ENSCLAP00000018112   ⟸   ENSCLAT00000018290
Protein Domains
PLD phosphodiesterase   PX


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012419 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018288 ENTREZGENE
  ENSCLAT00000018288.1 UniProtKB/TrEMBL
  ENSCLAT00000018289 ENTREZGENE
  ENSCLAT00000018289.1 UniProtKB/TrEMBL
  ENSCLAT00000018290 ENTREZGENE
  ENSCLAT00000018290.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
  Endonuclease Chain A UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PLD-like_dom UniProtKB/TrEMBL
  PLipase_D/transphosphatidylase UniProtKB/TrEMBL
  PLipase_D_euk UniProtKB/TrEMBL
  PLipase_D_fam UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
NCBI Gene Pld1 ENTREZGENE
PANTHER PHOSPHOLIPASE D1 UniProtKB/TrEMBL
  PTHR18896 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  PLDc UniProtKB/TrEMBL
  PLDc_2 UniProtKB/TrEMBL
PIRSF Phospholipase_D_euk UniProtKB/TrEMBL
PROSITE PLD UniProtKB/TrEMBL
  PS50195 UniProtKB/TrEMBL
SMART PLDc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Phospholipase D/nuclease UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A8C2VN51 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VN91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YRK8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Pld1  phospholipase D1    phospholipase D1, phosphatidylcholine-specific  Symbol and/or name change 5135510 APPROVED