SULT1A1 (sulfotransferase family 1A member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: SULT1A1 (sulfotransferase family 1A member 1) Homo sapiens
Analyze
Symbol: SULT1A1
Name: sulfotransferase family 1A member 1
RGD ID: 735435
HGNC Page HGNC
Description: Enables 3'-phosphoadenosine 5'-phosphosulfate binding activity and sulfotransferase activity. Involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; estrogen metabolic process; and ethanol catabolic process. Acts upstream of or within sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AC020765.6; aryl sulfotransferase 1; HAST1/HAST2; MGC131921; MGC5163; novel protein; P-PST; P-PST 1; phenol sulfotransferase 1; phenol-preferring phenol sulfotransferase1; phenol-sulfating phenol sulfotransferase 1; PST; ST1A1; ST1A3; STP; STP1; sulfotransferase 1A1; sulfotransferase family 1a, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; ts-PST; TSPST1
RGD Orthologs
Rat
Dog
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,605,258 - 28,623,375 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1628,603,944 - 28,623,625 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,616,579 - 28,634,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,524,414 - 28,542,367 (-)NCBINCBI36hg18NCBI36
Build 341628,524,418 - 28,542,367NCBI
Celera1627,573,787 - 27,591,759 (+)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1626,642,169 - 26,659,808 (-)NCBIHuRef
CHM1_11629,629,153 - 29,647,182 (-)NCBICHM1_1
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-schisandrin B  (ISO)
(S)-naringenin  (EXP,ISO)
(S)-ropivacaine  (EXP)
1,2-dimethylhydrazine  (ISO)
1-Hydroxypyrene  (EXP)
1-Methylpyrene  (EXP)
1-naphthol  (EXP)
11-deoxycorticosterone  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',4,5-tetrachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,5-dihydroxybenzoic acid  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-Amino-3-methyl-9H-pyrido[2,3-b]indole  (EXP)
2-amino-4,6-dinitrotoluene  (ISO)
2-Amino-9H-pyrido[2,3-b]indole  (EXP)
2-hydroxy-17beta-estradiol  (EXP)
2-methoxy-17beta-estradiol  (EXP)
2-methylcholine  (EXP)
2-naphthylamine  (EXP)
3'-phospho-5'-adenylyl sulfate  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5'-triiodo-L-thyronine  (EXP)
3,3',5'-triiodothyronine  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3,3'-diiodothyronine  (EXP)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-Hydroxybenzo[a]pyrene  (EXP)
3-methylcholanthrene  (EXP,ISO)
3-Nitrobenzanthrone  (EXP)
4-chlorobiphenyl  (EXP)
4-Hydroxy-N-desmethyltamoxifen  (EXP)
4-hydroxybenzoic acid  (EXP)
4-methylumbelliferone  (EXP,ISO)
4-nitrophenol  (EXP,ISO)
4-nonylphenol  (EXP)
4-octylphenol  (EXP)
5-hydroxyindole  (EXP,ISO)
5-hydroxymethylfurfural  (EXP,ISO)
5-Hydroxytryptophol  (EXP,ISO)
6-hydroxymelatonin  (EXP,ISO)
7,12-dimethyltetraphene  (ISO)
acetonitrile  (EXP)
actinomycin D  (EXP)
adenosine 3',5'-bismonophosphate  (ISO)
afimoxifene  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP)
Aloe emodin  (EXP)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
apigenin  (EXP)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (EXP)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene-7,8-dione  (EXP)
benzo[e]pyrene  (EXP)
benzyl alcohol  (EXP)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
biochanin A  (ISO)
biphenyl-4-amine  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butyric acid  (EXP)
cafestol  (EXP)
caffeine  (ISO)
carbamazepine  (ISO)
carbonyl sulfide  (ISO)
catechol  (EXP)
chrysin  (EXP)
chrysophanol  (EXP)
cis-caffeic acid  (EXP)
cisplatin  (EXP)
clofibrate  (ISO)
clotrimazole  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
crocidolite asbestos  (EXP)
cycloheximide  (EXP)
cyclosporin A  (EXP)
cylindrospermopsin  (EXP)
daidzein  (EXP)
decabromodiphenyl ether  (EXP)
deguelin  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (EXP)
diethyl maleate  (ISO)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (EXP)
dioxygen  (EXP)
diuron  (ISO)
dopamine  (EXP,ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
emodin  (EXP)
endosulfan  (ISO)
entinostat  (EXP)
estrone  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (EXP)
felbamate  (ISO)
fenbuconazole  (EXP)
ferulic acid  (ISO)
fipronil  (EXP,ISO)
flavonoids  (EXP)
folic acid  (EXP)
formaldehyde  (EXP)
furan  (ISO)
furfuryl alcohol  (EXP,ISO)
gabapentin  (ISO)
gallic acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
gentamycin  (ISO)
Glu-P-1  (EXP)
Glu-P-2  (EXP)
glutathione disulfide  (ISO)
heptachlor  (ISO)
hexachlorobenzene  (ISO)
hydrogen peroxide  (EXP)
indometacin  (ISO)
iodide salt  (ISO)
kahweol  (EXP)
ketamine  (ISO)
kojic acid  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
lidocaine  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
m-xylene  (ISO)
meclofenamic acid  (EXP)
mefenamic acid  (EXP,ISO)
mercury dibromide  (EXP)
methamphetamine  (ISO)
methanol  (EXP)
methapyrilene  (EXP,ISO)
methotrexate  (EXP)
methyl methanesulfonate  (EXP)
mifepristone  (ISO)
minoxidil  (EXP,ISO)
N,N-diethyl-m-toluamide  (EXP)
N,N-dimethylformamide  (EXP)
N-Desmethyltamoxifen  (EXP)
N-hydroxy-4-aminobiphenyl  (EXP)
N-hydroxy-PhIP  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
naphthalene  (ISO)
neoglucobrassicin  (EXP)
nevirapine  (ISO)
nickel dichloride  (ISO)
nimesulide  (EXP)
nitrofen  (EXP,ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
oxybenzone  (ISO)
oxycodone  (ISO)
p-chloromercuribenzoic acid  (EXP)
p-cresol  (ISO)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
pentachlorophenol  (EXP)
perfluorodecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenols  (ISO)
phentolamine  (EXP,ISO)
phenylmercury acetate  (EXP)
phenytoin  (ISO)
PhIP  (EXP,ISO)
physcion  (EXP)
picoxystrobin  (EXP)
pinocembrin  (EXP,ISO)
pirinixic acid  (ISO)
piroxicam  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (EXP)
resveratrol  (EXP)
Rhein  (EXP)
rotenone  (EXP,ISO)
salicylamide  (EXP,ISO)
SB 203580  (EXP)
SB 431542  (EXP)
scopolamine  (ISO)
serotonin  (EXP,ISO)
sevoflurane  (ISO)
sodium arsenite  (EXP)
sodium chloride  (EXP)
sodium dichromate  (ISO)
sunitinib  (EXP)
tamoxifen  (EXP)
tauroursodeoxycholic acid  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thyroxine  (EXP)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trans-caffeic acid  (EXP)
triamcinolone acetonide  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (EXP,ISO)
umbelliferone  (EXP,ISO)
ursodeoxycholic acid  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (EXP)
vinclozolin  (ISO)
xanthohumol  (EXP)
zaragozic acid A  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer. Bamber DE, etal., Pharmacogenetics. 2001 Nov;11(8):679-85.
2. Sulfotransferase 1A1 polymorphism and gastric cancer risk: a pilot case-control study. Boccia S, etal., Cancer Lett. 2005 Nov 18;229(2):235-43. Epub 2005 Aug 30.
3. Genetic polymorphisms of SULT1A1 and SULT1E1 and the risk and survival of breast cancer. Choi JY, etal., Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1090-5.
4. Human thyroid phenol sulfotransferase enzymes 1A1 and 1A3: activities in normal and diseased thyroid glands, and inhibition by thyroid hormones and phytoestrogens. Ebmeier CC and Anderson RJ, J Clin Endocrinol Metab. 2004 Nov;89(11):5597-605.
5. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
6. Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia. Gulyaeva LF, etal., Adv Exp Med Biol. 2008;617:359-66.
7. CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility. Hirata H, etal., Cancer. 2008 May 1;112(9):1964-73.
8. Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. Hou MF, etal., Int J Mol Med. 2002 Nov;10(5):609-12.
9. [Study on the relationship between polymorphisms of genes (CYP17, CYP19 and SULT1A1) and susceptibility to breast cancer in Chinese women] Hu MB, etal., Zhonghua Liu Xing Bing Xue Za Zhi. 2006 Apr;27(4):351-5.
10. Sulfotransferase1A1 and risk of postmenopausal breast cancer. Jerevall PL, etal., Anticancer Res. 2005 May-Jun;25(3c):2515-7.
11. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
12. Further evidence for null association of phenol sulfotransferase SULT1A1 polymorphism with prostate cancer risk: a case-control study of familial prostate cancer in a Japanese population. Koike H, etal., Int Urol Nephrol. 2008 Mar 27.
13. Epigenetic silencing of the sulfotransferase 1A1 gene by hypermethylation in breast tissue. Kwon MS, etal., Oncol Rep. 2006 Jan;15(1):27-32.
14. Genetic variants of the sulfotransferase 1A1 and breast cancer risk. Langsenlehner U, etal., Breast Cancer Res Treat. 2004 Sep;87(1):19-22.
15. Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen. Lazarus P, etal., Ann N Y Acad Sci. 2009 Feb;1155:99-111.
16. A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking. Liang G, etal., Carcinogenesis. 2004 May;25(5):773-8. Epub 2003 Dec 19.
17. Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis. McGill MR and Jaeschke H, Pharm Res. 2013 Sep;30(9):2174-87. doi: 10.1007/s11095-013-1007-6. Epub 2013 Mar 6.
18. Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk. Mikhailova ON, etal., Pharmacogenomics J. 2006 May-Jun;6(3):189-93.
19. Association of SULT1A1 phenotype and genotype with prostate cancer risk in African-Americans and Caucasians. Nowell S, etal., Cancer Epidemiol Biomarkers Prev. 2004 Feb;13(2):270-6.
20. The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese. Peng CT, etal., Int J Mol Med. 2003 Jan;11(1):85-9.
21. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
22. Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk. Rebbeck TR, etal., J Natl Cancer Inst. 2006 Sep 20;98(18):1311-20.
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. [Association of polymorphisms in SULT1A1 and UGT1A1 Genes with breast cancer risk and phenotypes in Russian women]. Shatalova EG, etal., Mol Biol (Mosk). 2006 Mar-Apr;40(2):263-70.
26. Phenol sulphotransferase SULT1A1 polymorphism in prostate cancer: lack of association. Steiner M, etal., Arch Toxicol. 2000 Jul;74(4-5):222-5.
27. Human NAD(P)H:quinone oxidoreductase 1 (NQO1) and sulfotransferase 1A1 (SULT1A1) polymorphisms and urothelial cancer risk in Taiwan. Wang YH, etal., J Cancer Res Clin Oncol. 2008 Feb;134(2):203-9. Epub 2007 Jul 10.
28. A physiogenomic approach to study the regulation of blood pressure. Westhoff TH, etal., Physiol Genomics. 2005 Sep 21;23(1):46-53. Epub 2005 Jun 7.
29. Association of the SULT1A1 R213H polymorphism with colorectal cancer. Wong CF, etal., Clin Exp Pharmacol Physiol. 2002 Sep;29(9):754-8.
30. SULT1A1 polymorphism and esophageal cancer in males. Wu MT, etal., Int J Cancer. 2003 Jan 1;103(1):101-4.
31. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
32. Modifying effects of sulfotransferase 1A1 gene polymorphism on the association of breast cancer risk with body mass index or endogenous steroid hormones. Yang G, etal., Breast Cancer Res Treat. 2005 Nov;94(1):63-70.
33. Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study. Zheng L, etal., Cancer Lett. 2003 Dec 8;202(1):61-9.
Additional References at PubMed
PMID:7581483   PMID:7695643   PMID:7864863   PMID:8033246   PMID:8033270   PMID:8093002   PMID:8288252   PMID:8363592   PMID:8423770   PMID:8484775   PMID:8661000   PMID:8889548  
PMID:8912648   PMID:8924211   PMID:9014197   PMID:9034160   PMID:9345314   PMID:9566757   PMID:9855620   PMID:10720750   PMID:10737800   PMID:10762004   PMID:11154739   PMID:11156380  
PMID:11207031   PMID:11219777   PMID:11470991   PMID:11535246   PMID:11739018   PMID:11804685   PMID:12162852   PMID:12402313   PMID:12419790   PMID:12419832   PMID:12468438   PMID:12471039  
PMID:12477932   PMID:12725421   PMID:12761191   PMID:12814450   PMID:12867416   PMID:12867492   PMID:14520706   PMID:14618622   PMID:14642079   PMID:14648207   PMID:14871892   PMID:15090717  
PMID:15093672   PMID:15122594   PMID:15318931   PMID:15383623   PMID:15455371   PMID:15489334   PMID:15489335   PMID:15516026   PMID:15604994   PMID:15632378   PMID:15743503   PMID:15949571  
PMID:15952058   PMID:15970794   PMID:15987423   PMID:16006997   PMID:16103451   PMID:16133548   PMID:16141802   PMID:16221673   PMID:16232327   PMID:16272171   PMID:16280036   PMID:16284375  
PMID:16317586   PMID:16380991   PMID:16395669   PMID:16418064   PMID:16425401   PMID:16504378   PMID:16575574   PMID:16926176   PMID:16985032   PMID:17013894   PMID:17074589   PMID:17189289  
PMID:17244352   PMID:17274372   PMID:17293380   PMID:17372239   PMID:17372243   PMID:17425406   PMID:17479406   PMID:17603900   PMID:17605044   PMID:17912498   PMID:17947222   PMID:17996038  
PMID:18006944   PMID:18259693   PMID:18264785   PMID:18365755   PMID:18447907   PMID:18499698   PMID:18632753   PMID:18794456   PMID:18854828   PMID:18990750   PMID:19120511   PMID:19126640  
PMID:19237513   PMID:19307236   PMID:19322015   PMID:19339270   PMID:19343046   PMID:19350537   PMID:19424794   PMID:19484729   PMID:19548878   PMID:19575027   PMID:19706609   PMID:19776291  
PMID:19789190   PMID:19863350   PMID:19904771   PMID:19906068   PMID:19915574   PMID:19949855   PMID:19956635   PMID:20032816   PMID:20056724   PMID:20142249   PMID:20192879   PMID:20204402  
PMID:20214802   PMID:20309015   PMID:20417180   PMID:20437850   PMID:20505544   PMID:20505990   PMID:20528568   PMID:20529763   PMID:20565970   PMID:20620409   PMID:20628863   PMID:20634891  
PMID:20663177   PMID:20734064   PMID:20881232   PMID:20936502   PMID:21072184   PMID:21111704   PMID:21670965   PMID:21695180   PMID:21873635   PMID:21977969   PMID:22011087   PMID:22081606  
PMID:22524828   PMID:22678655   PMID:22708928   PMID:22939629   PMID:23080433   PMID:23128233   PMID:23157889   PMID:23207770   PMID:23358261   PMID:23711090   PMID:24010997   PMID:24039991  
PMID:24307569   PMID:24763827   PMID:24797263   PMID:25103078   PMID:25194687   PMID:25201988   PMID:25225888   PMID:25314023   PMID:25370010   PMID:25385181   PMID:25416956   PMID:25654087  
PMID:25771868   PMID:25819444   PMID:25910212   PMID:26022216   PMID:26067475   PMID:26169578   PMID:26186194   PMID:26340710   PMID:26344197   PMID:26455829   PMID:26906565   PMID:27207664  
PMID:27221864   PMID:27300114   PMID:27356022   PMID:28160022   PMID:28326452   PMID:28514442   PMID:28523759   PMID:28589969   PMID:28712289   PMID:28867356   PMID:28887105   PMID:29110586  
PMID:29233949   PMID:29790428   PMID:29908303   PMID:30120701   PMID:31091453   PMID:31515488   PMID:31671219   PMID:31835852   PMID:31871319   PMID:32152050   PMID:33049293   PMID:33297275  
PMID:33961781   PMID:34079125   PMID:34162941   PMID:34299191  


Genomics

Comparative Map Data
SULT1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,605,258 - 28,623,375 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1628,603,944 - 28,623,625 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,616,579 - 28,634,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,524,414 - 28,542,367 (-)NCBINCBI36hg18NCBI36
Build 341628,524,418 - 28,542,367NCBI
Celera1627,573,787 - 27,591,759 (+)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1626,642,169 - 26,659,808 (-)NCBIHuRef
CHM1_11629,629,153 - 29,647,182 (-)NCBICHM1_1
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sult1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21181,272,022 - 181,276,750 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1181,272,023 - 181,275,562 (-)Ensembl
Rnor_6.01198,100,586 - 198,104,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,100,586 - 198,104,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,079,585 - 205,083,105 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,829,205 - 185,832,725 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,979,085 - 185,982,606 (-)NCBI
Celera1178,929,499 - 178,933,019 (-)NCBICelera
Cytogenetic Map1q36NCBI
SULT1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,176,156 - 18,179,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,176,355 - 18,179,489 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,755,231 - 19,758,321 (+)NCBI
ROS_Cfam_1.0618,312,221 - 18,315,557 (+)NCBI
ROS_Cfam_1.0 Ensembl618,312,420 - 18,315,554 (+)Ensembl
UMICH_Zoey_3.1618,111,461 - 18,114,551 (+)NCBI
UNSW_CanFamBas_1.0618,026,685 - 18,029,775 (+)NCBI
UU_Cfam_GSD_1.0618,342,761 - 18,345,851 (+)NCBI
LOC101697399
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478213,079,596 - 13,094,149 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH70266  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371628,617,096 - 28,617,206UniSTSGRCh37
GRCh371628,603,303 - 28,603,413UniSTSGRCh37
Build 361628,510,804 - 28,510,914RGDNCBI36
Celera1627,591,466 - 27,591,576RGD
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map16p11.2UniSTS
HuRef1626,628,913 - 26,629,023UniSTS
HuRef1626,642,357 - 26,642,467UniSTS
GDB:574032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371628,619,661 - 28,620,185UniSTSGRCh37
GRCh371628,606,737 - 28,607,260UniSTSGRCh37
Build 361628,514,238 - 28,514,761RGDNCBI36
Celera1627,588,489 - 27,589,013RGD
Cytogenetic Map16p12.1UniSTS
HuRef1626,632,347 - 26,632,870UniSTS
HuRef1626,644,924 - 26,645,448UniSTS
GDB:625673  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371628,618,329 - 28,619,822UniSTSGRCh37
Build 361628,525,830 - 28,527,323RGDNCBI36
Cytogenetic Map16p12.1UniSTS
GDB:625839  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371628,619,655 - 28,621,274UniSTSGRCh37
GRCh371628,606,731 - 28,608,340UniSTSGRCh37
Build 361628,514,232 - 28,515,841RGDNCBI36
Celera1627,587,400 - 27,589,019RGD
Cytogenetic Map16p12.1UniSTS
HuRef1626,632,341 - 26,633,950UniSTS
HuRef1626,644,918 - 26,646,537UniSTS
GDB:625858  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371628,619,773 - 28,619,949UniSTSGRCh37
GRCh371628,606,849 - 28,607,021UniSTSGRCh37
Build 361628,514,350 - 28,514,522RGDNCBI36
Celera1627,588,725 - 27,588,901RGD
Cytogenetic Map16p12.1UniSTS
HuRef1626,632,459 - 26,632,631UniSTS
HuRef1626,645,036 - 26,645,212UniSTS
GDB:579633  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map16p12.1UniSTS
GDB:594646  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map16p11.2UniSTS
GDB:625988  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16p12.1UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR631hsa-miR-631Mirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI20881232

Predicted Target Of
Summary Value
Count of predictions:3613
Count of miRNA genes:793
Interacting mature miRNAs:931
Transcripts:ENST00000314752, ENST00000350842, ENST00000395607, ENST00000395609, ENST00000562058, ENST00000563493, ENST00000564818, ENST00000566189, ENST00000567512, ENST00000567998, ENST00000569554
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 934 1004 1619 464 1083 394 857 211 2863 161 778 1335 71 714 566
Low 1495 1966 98 155 458 65 3425 1961 811 251 653 240 100 1 490 2207 3 2
Below cutoff 8 17 8 5 279 6 67 20 58 7 25 35 2 15 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_028128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047434550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001751973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB062428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB209149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC020765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ007418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL558375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG482944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG990719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI459867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI460081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM927749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM984308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT007324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV023878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L10819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L15346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U26309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U37025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U52852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U54701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U71086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X84654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000314752   ⟹   ENSP00000321988
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,258 - 28,610,044 (-)Ensembl
RefSeq Acc Id: ENST00000350842   ⟹   ENSP00000329399
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,582 - 28,623,586 (-)Ensembl
RefSeq Acc Id: ENST00000395607   ⟹   ENSP00000378971
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,597 - 28,609,328 (-)Ensembl
RefSeq Acc Id: ENST00000395609   ⟹   ENSP00000378972
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,603,944 - 28,623,555 (-)Ensembl
RefSeq Acc Id: ENST00000562058   ⟹   ENSP00000456215
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,592 - 28,623,553 (-)Ensembl
RefSeq Acc Id: ENST00000563493   ⟹   ENSP00000457083
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,628 - 28,623,625 (-)Ensembl
RefSeq Acc Id: ENST00000564818   ⟹   ENSP00000454388
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,587 - 28,623,252 (-)Ensembl
RefSeq Acc Id: ENST00000566189   ⟹   ENSP00000456459
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,865 - 28,609,990 (-)Ensembl
RefSeq Acc Id: ENST00000567512   ⟹   ENSP00000455979
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,606,196 - 28,610,032 (-)Ensembl
RefSeq Acc Id: ENST00000567998
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,591 - 28,614,279 (-)Ensembl
RefSeq Acc Id: ENST00000569554   ⟹   ENSP00000457912
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1628,605,196 - 28,608,920 (-)Ensembl
RefSeq Acc Id: NM_001055   ⟹   NP_001046
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
GRCh371628,616,908 - 28,634,907 (-)NCBI
Build 361628,524,419 - 28,528,858 (-)NCBI Archive
HuRef1626,642,169 - 26,659,808 (-)NCBI
CHM1_11629,629,153 - 29,633,612 (-)NCBI
T2T-CHM13v2.01628,785,654 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001394421   ⟹   NP_001381350
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001394422   ⟹   NP_001381351
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001394423   ⟹   NP_001381352
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001394424   ⟹   NP_001381353
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001394425   ⟹   NP_001381354
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_177529   ⟹   NP_803565
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
GRCh371628,616,908 - 28,634,907 (-)NCBI
Build 361628,524,419 - 28,528,858 (-)NCBI Archive
HuRef1626,642,169 - 26,659,808 (-)NCBI
CHM1_11629,629,153 - 29,633,612 (-)NCBI
T2T-CHM13v2.01628,785,654 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_177530   ⟹   NP_803566
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
GRCh371628,616,908 - 28,634,907 (-)NCBI
Build 361628,524,414 - 28,528,150 (-)NCBI Archive
HuRef1626,642,169 - 26,659,808 (-)NCBI
CHM1_11629,629,153 - 29,632,896 (-)NCBI
T2T-CHM13v2.01628,785,654 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_177534   ⟹   NP_803878
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
GRCh371628,616,908 - 28,634,907 (-)NCBI
Build 361628,524,414 - 28,528,150 (-)NCBI Archive
HuRef1626,642,169 - 26,659,808 (-)NCBI
CHM1_11629,629,153 - 29,632,896 (-)NCBI
T2T-CHM13v2.01628,785,654 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: NM_177536   ⟹   NP_803880
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
GRCh371628,616,908 - 28,634,907 (-)NCBI
Build 361628,524,414 - 28,542,367 (-)NCBI Archive
HuRef1626,642,169 - 26,659,808 (-)NCBI
CHM1_11629,629,153 - 29,647,182 (-)NCBI
T2T-CHM13v2.01628,772,308 - 28,790,437 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017023604   ⟹   XP_016879093
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017023605   ⟹   XP_016879094
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017023608   ⟹   XP_016879097
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017023610   ⟹   XP_016879099
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047434544   ⟹   XP_047290500
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,620,135 (-)NCBI
RefSeq Acc Id: XM_047434545   ⟹   XP_047290501
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
RefSeq Acc Id: XM_047434546   ⟹   XP_047290502
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
RefSeq Acc Id: XM_047434547   ⟹   XP_047290503
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
RefSeq Acc Id: XM_047434548   ⟹   XP_047290504
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,610,044 (-)NCBI
RefSeq Acc Id: XM_047434549   ⟹   XP_047290505
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,605,258 - 28,623,375 (-)NCBI
RefSeq Acc Id: XM_047434550   ⟹   XP_047290506
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,606,079 - 28,610,044 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001046 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381350 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381351 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381352 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381353 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381354 (Get FASTA)   NCBI Sequence Viewer  
  NP_803565 (Get FASTA)   NCBI Sequence Viewer  
  NP_803566 (Get FASTA)   NCBI Sequence Viewer  
  NP_803878 (Get FASTA)   NCBI Sequence Viewer  
  NP_803880 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879093 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879094 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879097 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879099 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290500 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290501 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290502 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290503 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290504 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290505 (Get FASTA)   NCBI Sequence Viewer  
  XP_047290506 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA02935 (Get FASTA)   NCBI Sequence Viewer  
  AAA18613 (Get FASTA)   NCBI Sequence Viewer  
  AAA35562 (Get FASTA)   NCBI Sequence Viewer  
  AAA60595 (Get FASTA)   NCBI Sequence Viewer  
  AAA67895 (Get FASTA)   NCBI Sequence Viewer  
  AAA99892 (Get FASTA)   NCBI Sequence Viewer  
  AAB09597 (Get FASTA)   NCBI Sequence Viewer  
  AAB09759 (Get FASTA)   NCBI Sequence Viewer  
  AAC50480 (Get FASTA)   NCBI Sequence Viewer  
  AAC51816 (Get FASTA)   NCBI Sequence Viewer  
  AAH00923 (Get FASTA)   NCBI Sequence Viewer  
  AAI10888 (Get FASTA)   NCBI Sequence Viewer  
  AAP35988 (Get FASTA)   NCBI Sequence Viewer  
  BAB93491 (Get FASTA)   NCBI Sequence Viewer  
  BAD92386 (Get FASTA)   NCBI Sequence Viewer  
  CAA07495 (Get FASTA)   NCBI Sequence Viewer  
  CAA55089 (Get FASTA)   NCBI Sequence Viewer  
  CAA59147 (Get FASTA)   NCBI Sequence Viewer  
  P50225 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_803880   ⟸   NM_177536
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: NP_803566   ⟸   NM_177530
- Peptide Label: isoform a
- UniProtKB: P50225 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_803878   ⟸   NM_177534
- Peptide Label: isoform a
- UniProtKB: P50225 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001046   ⟸   NM_001055
- Peptide Label: isoform a
- UniProtKB: P50225 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_803565   ⟸   NM_177529
- Peptide Label: isoform a
- UniProtKB: P50225 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016879094   ⟸   XM_017023605
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016879093   ⟸   XM_017023604
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016879097   ⟸   XM_017023608
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016879099   ⟸   XM_017023610
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000457912   ⟸   ENST00000569554
RefSeq Acc Id: ENSP00000329399   ⟸   ENST00000350842
RefSeq Acc Id: ENSP00000456215   ⟸   ENST00000562058
RefSeq Acc Id: ENSP00000457083   ⟸   ENST00000563493
RefSeq Acc Id: ENSP00000321988   ⟸   ENST00000314752
RefSeq Acc Id: ENSP00000454388   ⟸   ENST00000564818
RefSeq Acc Id: ENSP00000456459   ⟸   ENST00000566189
RefSeq Acc Id: ENSP00000378972   ⟸   ENST00000395609
RefSeq Acc Id: ENSP00000378971   ⟸   ENST00000395607
RefSeq Acc Id: ENSP00000455979   ⟸   ENST00000567512
RefSeq Acc Id: NP_001381353   ⟸   NM_001394424
- Peptide Label: isoform a
RefSeq Acc Id: NP_001381354   ⟸   NM_001394425
- Peptide Label: isoform a
RefSeq Acc Id: NP_001381350   ⟸   NM_001394421
- Peptide Label: isoform a
RefSeq Acc Id: NP_001381352   ⟸   NM_001394423
- Peptide Label: isoform a
RefSeq Acc Id: NP_001381351   ⟸   NM_001394422
- Peptide Label: isoform a
RefSeq Acc Id: XP_047290505   ⟸   XM_047434549
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047290503   ⟸   XM_047434547
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047290500   ⟸   XM_047434544
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047290502   ⟸   XM_047434546
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047290501   ⟸   XM_047434545
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047290504   ⟸   XM_047434548
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047290506   ⟸   XM_047434550
- Peptide Label: isoform X4
Protein Domains
Sulfotransfer_1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50225-F1-model_v2 AlphaFold P50225 1-295 view protein structure

Promoters
RGD ID:6793068
Promoter ID:HG_KWN:23402
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000395632,   UC002DQK.1,   UC002DQL.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361628,528,536 - 28,529,036 (-)MPROMDB
RGD ID:6793489
Promoter ID:HG_KWN:23403
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000254693,   UC002DQN.1,   UC002DQO.1,   UC002DQP.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361628,542,046 - 28,542,546 (-)MPROMDB
RGD ID:7231735
Promoter ID:EPDNEW_H21614
Type:initiation region
Name:SULT1A1_1
Description:sulfotransferase family 1A member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H21617  EPDNEW_H21618  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,610,004 - 28,610,064EPDNEW
RGD ID:7231743
Promoter ID:EPDNEW_H21617
Type:initiation region
Name:SULT1A1_3
Description:sulfotransferase family 1A member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H21614  EPDNEW_H21618  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,623,342 - 28,623,402EPDNEW
RGD ID:7231745
Promoter ID:EPDNEW_H21618
Type:initiation region
Name:SULT1A1_2
Description:sulfotransferase family 1A member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H21614  EPDNEW_H21617  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381628,623,572 - 28,623,632EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 16p12.2-11.2(chr16:21463739-29249579)x3 copy number gain See cases [RCV000051829] Chr16:21463739..29249579 [GRCh38]
Chr16:21475060..29260900 [GRCh37]
Chr16:21382561..29168401 [NCBI36]
Chr16:16p12.2-11.2
pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:21602183-29314373)x3 copy number gain See cases [RCV000051842] Chr16:21602183..29314373 [GRCh38]
Chr16:21613504..29325694 [GRCh37]
Chr16:21521005..29233195 [NCBI36]
Chr16:16p12.2-11.2
pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:23047969-30632245)x3 copy number gain See cases [RCV000052401] Chr16:23047969..30632245 [GRCh38]
Chr16:23059290..30643566 [GRCh37]
Chr16:22966791..30551067 [NCBI36]
Chr16:16p12.2-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28456967-30295107)x1 copy number loss See cases [RCV000052520] Chr16:28456967..30295107 [GRCh38]
Chr16:28468288..30306428 [GRCh37]
Chr16:28375789..30213929 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28293803-29531653)x3 copy number gain See cases [RCV000053118] Chr16:28293803..29531653 [GRCh38]
Chr16:28305124..29542974 [GRCh37]
Chr16:28212625..29450475 [NCBI36]
Chr16:16p12.1-11.2
uncertain significance
GRCh38/hg38 16p11.2(chr16:28589904-29030797)x3 copy number gain See cases [RCV000053119] Chr16:28589904..29030797 [GRCh38]
Chr16:28601225..29042118 [GRCh37]
Chr16:28508726..28949619 [NCBI36]
Chr16:16p11.2
uncertain significance
GRCh38/hg38 16p11.2(chr16:28592408-29025786)x3 copy number gain See cases [RCV000053120] Chr16:28592408..29025786 [GRCh38]
Chr16:28603729..29037107 [GRCh37]
Chr16:28511230..28944608 [NCBI36]
Chr16:16p11.2
uncertain significance
GRCh38/hg38 16p11.2(chr16:28599237-29025786)x3 copy number gain See cases [RCV000053121] Chr16:28599237..29025786 [GRCh38]
Chr16:28610558..29037107 [GRCh37]
Chr16:28518059..28944608 [NCBI36]
Chr16:16p11.2
uncertain significance
GRCh38/hg38 16p11.2(chr16:28531783-29025786)x1 copy number loss See cases [RCV000053490] Chr16:28531783..29025786 [GRCh38]
Chr16:28543104..29037107 [GRCh37]
Chr16:28450605..28944608 [NCBI36]
Chr16:16p11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28492482-30179247)x1 copy number loss See cases [RCV000054252] Chr16:28492482..30179247 [GRCh38]
Chr16:28503803..30190568 [GRCh37]
Chr16:28411304..30098069 [NCBI36]
Chr16:16p12.1-11.2
pathogenic|uncertain significance|conflicting data from submitters
GRCh38/hg38 16p11.2(chr16:28531783-30183432)x1 copy number loss See cases [RCV000054253] Chr16:28531783..30183432 [GRCh38]
Chr16:28543104..30194753 [GRCh37]
Chr16:28450605..30102254 [NCBI36]
Chr16:16p11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28366111-30183432)x3 copy number gain See cases [RCV000054346] Chr16:28366111..30183432 [GRCh38]
Chr16:28377432..30194753 [GRCh37]
Chr16:28284933..30102254 [NCBI36]
Chr16:16p12.1-11.2
pathogenic|uncertain significance
NM_177530.2(SULT1A1):c.-1009C>T single nucleotide variant Malignant melanoma [RCV000071073] Chr16:28610063 [GRCh38]
Chr16:28621384 [GRCh37]
Chr16:28528885 [NCBI36]
Chr16:16p11.2
not provided
GRCh38/hg38 16p13.3-11.2(chr16:4644892-29170820)x3 copy number gain See cases [RCV000133809] Chr16:4644892..29170820 [GRCh38]
Chr16:4694893..29182141 [GRCh37]
Chr16:4634894..29089642 [NCBI36]
Chr16:16p13.3-11.2
pathogenic
GRCh38/hg38 16p11.2(chr16:28584316-29019738)x3 copy number gain See cases [RCV000134985] Chr16:28584316..29019738 [GRCh38]
Chr16:28595637..29031059 [GRCh37]
Chr16:28503138..28938560 [NCBI36]
Chr16:16p11.2
likely pathogenic|conflicting data from submitters
GRCh38/hg38 16p12.1-11.2(chr16:28492482-29320029)x3 copy number gain See cases [RCV000135755] Chr16:28492482..29320029 [GRCh38]
Chr16:28503803..29331350 [GRCh37]
Chr16:28411304..29238851 [NCBI36]
Chr16:16p12.1-11.2
uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28492482-29170875)x1 copy number loss See cases [RCV000135759] Chr16:28492482..29170875 [GRCh38]
Chr16:28503803..29182196 [GRCh37]
Chr16:28411304..29089697 [NCBI36]
Chr16:16p12.1-11.2
likely pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28492482-30179247)x3 copy number gain See cases [RCV000135765] Chr16:28492482..30179247 [GRCh38]
Chr16:28503803..30190568 [GRCh37]
Chr16:28411304..30098069 [NCBI36]
Chr16:16p12.1-11.2
pathogenic|uncertain significance
GRCh38/hg38 16p12.2-11.2(chr16:22634385-29227323)x3 copy number gain See cases [RCV000135594] Chr16:22634385..29227323 [GRCh38]
Chr16:22645706..29238644 [GRCh37]
Chr16:22553207..29146145 [NCBI36]
Chr16:16p12.2-11.2
likely pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28487211-29202837)x3 copy number gain See cases [RCV000137571] Chr16:28487211..29202837 [GRCh38]
Chr16:28498532..29214158 [GRCh37]
Chr16:28406033..29121659 [NCBI36]
Chr16:16p12.1-11.2
uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28392832-30186020)x1 copy number loss See cases [RCV000137580] Chr16:28392832..30186020 [GRCh38]
Chr16:28404153..30197341 [GRCh37]
Chr16:28311654..30104842 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28327346-29342070)x1 copy number loss See cases [RCV000137848] Chr16:28327346..29342070 [GRCh38]
Chr16:28338667..29353391 [GRCh37]
Chr16:28246168..29260892 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-29342070)x1 copy number loss See cases [RCV000137949] Chr16:28392832..29342070 [GRCh38]
Chr16:28404153..29353391 [GRCh37]
Chr16:28311654..29260892 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392026-29170879)x3 copy number gain See cases [RCV000139217] Chr16:28392026..29170879 [GRCh38]
Chr16:28403347..29182200 [GRCh37]
Chr16:28310848..29089701 [NCBI36]
Chr16:16p12.1-11.2
uncertain significance
GRCh38/hg38 16p12.2-11.2(chr16:21350622-29202837)x3 copy number gain See cases [RCV000140235] Chr16:21350622..29202837 [GRCh38]
Chr16:21361943..29214158 [GRCh37]
Chr16:21269444..29121659 [NCBI36]
Chr16:16p12.2-11.2
likely pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-30320693)x1 copy number loss See cases [RCV000139916] Chr16:28392832..30320693 [GRCh38]
Chr16:28404153..30332014 [GRCh37]
Chr16:28311654..30239515 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:27311746-31193406)x3 copy number gain See cases [RCV000140341] Chr16:27311746..31193406 [GRCh38]
Chr16:27323067..31204727 [GRCh37]
Chr16:27230568..31112228 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-29320029)x1 copy number loss See cases [RCV000139466] Chr16:28392832..29320029 [GRCh38]
Chr16:28404153..29331350 [GRCh37]
Chr16:28311654..29238851 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:23752047-31943755)x3 copy number gain See cases [RCV000141141] Chr16:23752047..31943755 [GRCh38]
Chr16:23763368..31955076 [GRCh37]
Chr16:23670869..31862577 [NCBI36]
Chr16:16p12.2-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-29170875)x1 copy number loss See cases [RCV000140694] Chr16:28392832..29170875 [GRCh38]
Chr16:28404153..29182196 [GRCh37]
Chr16:28311654..29089697 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28320366-29415078)x3 copy number gain See cases [RCV000141716] Chr16:28320366..29415078 [GRCh38]
Chr16:28331687..29426399 [GRCh37]
Chr16:28239188..29333900 [NCBI36]
Chr16:16p12.1-11.2
uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28492482-29170875)x3 copy number gain See cases [RCV000142569] Chr16:28492482..29170875 [GRCh38]
Chr16:28503803..29182196 [GRCh37]
Chr16:28411304..29089697 [NCBI36]
Chr16:16p12.1-11.2
uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28492482-30179247)x1 copy number loss See cases [RCV000148148] Chr16:28492482..30179247 [GRCh38]
Chr16:28503803..30190568 [GRCh37]
Chr16:28411304..30098069 [NCBI36]
Chr16:16p12.1-11.2
pathogenic
GRCh38/hg38 16p11.2(chr16:28589904-29030797)x3 copy number gain See cases [RCV000148153] Chr16:28589904..29030797 [GRCh38]
Chr16:28601225..29042118 [GRCh37]
Chr16:28508726..28949619 [NCBI36]
Chr16:16p11.2
uncertain significance
NC_000016.10:g.28592568_28609431dup duplication Preeclampsia [RCV000161787] Chr16:28592568..28609431 [GRCh38]
Chr16:28603889..28620752 [GRCh37]
Chr16:16p11.2
not provided
GRCh37/hg19 16p11.2(chr16:28484556-29043450)x1 copy number loss See cases [RCV000258804] Chr16:28484556..29043450 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28631584-29095327)x3 copy number gain See cases [RCV000449070] Chr16:28631584..29095327 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p12.3-11.2(chr16:19590412-29814175)x3 copy number gain Ductal breast carcinoma [RCV000207226] Chr16:19590412..29814175 [GRCh37]
Chr16:16p12.3-11.2
uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:1279324-31926800)x3 copy number gain Ductal breast carcinoma [RCV000207053] Chr16:1279324..31926800 [GRCh37]
Chr16:16p13.3-11.2
uncertain significance
GRCh37/hg19 16p11.2(chr16:28486693-29043960)x1 copy number loss See cases [RCV000240493] Chr16:28486693..29043960 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p12.3-11.2(chr16:19424115-30142220)x3 copy number gain See cases [RCV000449403] Chr16:19424115..30142220 [GRCh37]
Chr16:16p12.3-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28486693-30197290)x1 copy number loss See cases [RCV000447001] Chr16:28486693..30197290 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28486693-29048572)x1 copy number loss See cases [RCV000447021] Chr16:28486693..29048572 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3 copy number gain See cases [RCV000446684] Chr16:69193..90274381 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
NC_000016.10:g.(?_28370872)_(29324276_?)del deletion Schizophrenia [RCV000416901] Chr16:28370872..29324276 [GRCh38]
Chr16:28382193..29335597 [GRCh37]
Chr16:28289694..29243098 [NCBI36]
Chr16:16p12.1-11.2
likely pathogenic
GRCh37/hg19 16p11.2(chr16:28384463-29343462)x1 copy number loss See cases [RCV000510329] Chr16:28384463..29343462 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3 copy number gain See cases [RCV000511622] Chr16:9273328..89548493 [GRCh37]
Chr16:16p13.2-q24.3
uncertain significance
GRCh37/hg19 16p11.2(chr16:28441538-30178406)x1 copy number loss See cases [RCV000511533] Chr16:28441538..30178406 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:22718350-28858721)x4 copy number gain See cases [RCV000511587] Chr16:22718350..28858721 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28371467-29426399)x4 copy number gain See cases [RCV000511109] Chr16:28371467..29426399 [GRCh37]
Chr16:16p11.2
uncertain significance
GRCh37/hg19 16p11.2(chr16:28466730-29427247)x1 copy number loss See cases [RCV000510933] Chr16:28466730..29427247 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21596299-30399167)x1 copy number loss See cases [RCV000511271] Chr16:21596299..30399167 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
maternal UPD(16p) complex Hemimegalencephaly [RCV000494707] Chr16:1280042..33710558 [GRCh37]
Chr16:16p13.3-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28529940-28906458) copy number loss Distal 16p11.2 microdeletion syndrome [RCV000767608] Chr16:28529940..28906458 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062) copy number gain See cases [RCV000511296] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3 copy number gain See cases [RCV000512138] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p12.3-11.2(chr16:18238275-30177240)x3 copy number gain See cases [RCV000512428] Chr16:18238275..30177240 [GRCh37]
Chr16:16p12.3-11.2
pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21379628-29351826)x3 copy number gain See cases [RCV000512478] Chr16:21379628..29351826 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21379628-29379768)x1 copy number loss not provided [RCV000683786] Chr16:21379628..29379768 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28389576-29438326)x1 copy number loss not provided [RCV000683798] Chr16:28389576..29438326 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3 copy number gain not provided [RCV000738917] Chr16:88165..90163275 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3 copy number gain not provided [RCV000738918] Chr16:88165..90274695 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3 copy number gain not provided [RCV000738915] Chr16:61451..90294632 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p11.2(chr16:28603889-28620752)x1 copy number loss not provided [RCV000739107] Chr16:28603889..28620752 [GRCh37]
Chr16:16p11.2
benign
GRCh37/hg19 16p11.2(chr16:28607196-28762709)x1 copy number loss not provided [RCV000739108] Chr16:28607196..28762709 [GRCh37]
Chr16:16p11.2
benign
GRCh37/hg19 16p11.2(chr16:28608487-28652357)x1 copy number loss not provided [RCV000739109] Chr16:28608487..28652357 [GRCh37]
Chr16:16p11.2
benign
GRCh37/hg19 16p11.2(chr16:28613508-28719434)x1 copy number loss not provided [RCV000739110] Chr16:28613508..28719434 [GRCh37]
Chr16:16p11.2
benign
GRCh37/hg19 16p11.2(chr16:28613965-28630153)x3 copy number gain not provided [RCV000739111] Chr16:28613965..28630153 [GRCh37]
Chr16:16p11.2
benign
NC_000016.10:g.(?_28351819)_(29325073_?)del deletion Schizophrenia [RCV000754181] Chr16:28351819..29325073 [GRCh38]
Chr16:16p12.1-11.2
pathogenic
NC_000016.9:g.21530207_29332245del deletion not provided [RCV001030428] Chr16:21530207..29332245 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
NM_001055.4(SULT1A1):c.214C>T (p.Arg72Ter) single nucleotide variant not provided [RCV000784922] Chr16:28608538 [GRCh38]
Chr16:28619859 [GRCh37]
Chr16:16p11.2
uncertain significance
GRCh37/hg19 16p12.2-11.2(chr16:21312200-29646379)x3 copy number gain not provided [RCV001249228] Chr16:21312200..29646379 [GRCh37]
Chr16:16p12.2-11.2
not provided
GRCh37/hg19 16p11.2(chr16:28466730-30178406)x1 copy number loss not provided [RCV001006789] Chr16:28466730..30178406 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28466730-30177916)x1 copy number loss not provided [RCV000848428] Chr16:28466730..30177916 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28466730-30191848)x1 copy number loss not provided [RCV000846340] Chr16:28466730..30191848 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28371467-29416001)x3 copy number gain not provided [RCV000846620] Chr16:28371467..29416001 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21576802-29351826)x3 copy number gain not provided [RCV001006786] Chr16:21576802..29351826 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28545586-29351826)x3 copy number gain not provided [RCV001006790] Chr16:28545586..29351826 [GRCh37]
Chr16:16p11.2
uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:5805001-34230001) copy number gain Microcephaly [RCV001252948] Chr16:5805001..34230001 [GRCh37]
Chr16:16p13.3-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28336673-29358712)x1 copy number loss not provided [RCV001258615] Chr16:28336673..29358712 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p13.3-11.2(chr16:2959279-30190593)x3 copy number gain See cases [RCV001263169] Chr16:2959279..30190593 [GRCh37]
Chr16:16p13.3-11.2
pathogenic|likely pathogenic
GRCh37/hg19 16p11.2(chr16:28488319-30178406)x1 copy number loss not provided [RCV001258616] Chr16:28488319..30178406 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28384463-29343462)x3 copy number gain not provided [RCV001258621] Chr16:28384463..29343462 [GRCh37]
Chr16:16p11.2
uncertain significance
GRCh37/hg19 16p11.2(chr16:28483631-29332591)x3 copy number gain not provided [RCV001270661] Chr16:28483631..29332591 [GRCh37]
Chr16:16p11.2
uncertain significance
GRCh37/hg19 16p11.2(chr16:28615644-29042118) copy number gain Atrioventricular septal defect [RCV001291965] Chr16:28615644..29042118 [GRCh37]
Chr16:16p11.2
pathogenic
NC_000016.9:g.(?_28488827)_(28950294_?)del deletion Neuronal ceroid lipofuscinosis [RCV001387099] Chr16:28488827..28950294 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21594997-29625302)x1 copy number loss not provided [RCV001795549] Chr16:21594997..29625302 [GRCh37]
Chr16:16p12.2-11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28353878-29478115)x3 copy number gain Distal 16p11.2 microdeletion syndrome [RCV001801190] Chr16:28353878..29478115 [GRCh37]
Chr16:16p11.2
likely pathogenic
GRCh37/hg19 16p11.2(chr16:28485883-29416001)x1 copy number loss not provided [RCV001829191] Chr16:28485883..29416001 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28485883-29589674)x1 copy number loss not provided [RCV001834285] Chr16:28485883..29589674 [GRCh37]
Chr16:16p11.2
pathogenic
GRCh37/hg19 16p11.2(chr16:28384465-29351826)x3 copy number gain not provided [RCV001827743] Chr16:28384465..29351826 [GRCh37]
Chr16:16p11.2
uncertain significance
Single allele deletion Distal 16p11.2 microdeletion syndrome [RCV002227715] Chr16:28814284..29032129 [GRCh38]
Chr16:16p11.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11453 AgrOrtholog
COSMIC SULT1A1 COSMIC
Ensembl Genes ENSG00000196502 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000288656 UniProtKB/TrEMBL
Ensembl Protein ENSP00000321988 ENTREZGENE
  ENSP00000321988.7 UniProtKB/Swiss-Prot
  ENSP00000329399 ENTREZGENE
  ENSP00000329399.4 UniProtKB/Swiss-Prot
  ENSP00000378971.2 UniProtKB/TrEMBL
  ENSP00000454388.1 UniProtKB/TrEMBL
  ENSP00000455979.1 UniProtKB/TrEMBL
  ENSP00000456215.1 UniProtKB/TrEMBL
  ENSP00000456459 ENTREZGENE
  ENSP00000456459.1 UniProtKB/TrEMBL
  ENSP00000457083.1 UniProtKB/TrEMBL
  ENSP00000457912 ENTREZGENE
  ENSP00000457912.1 UniProtKB/Swiss-Prot
  ENSP00000502863.1 UniProtKB/TrEMBL
  ENSP00000503077.1 UniProtKB/TrEMBL
Ensembl Transcript ENST00000314752 ENTREZGENE
  ENST00000314752.12 UniProtKB/Swiss-Prot
  ENST00000350842 ENTREZGENE
  ENST00000350842.8 UniProtKB/Swiss-Prot
  ENST00000395607.6 UniProtKB/TrEMBL
  ENST00000562058.5 UniProtKB/TrEMBL
  ENST00000563493.1 UniProtKB/TrEMBL
  ENST00000564818.5 UniProtKB/TrEMBL
  ENST00000566189 ENTREZGENE
  ENST00000566189.5 UniProtKB/TrEMBL
  ENST00000567512.1 UniProtKB/TrEMBL
  ENST00000569554 ENTREZGENE
  ENST00000569554.5 UniProtKB/Swiss-Prot
  ENST00000677940.1 UniProtKB/TrEMBL
  ENST00000679262.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000196502 GTEx
  ENSG00000288656 GTEx
HGNC ID HGNC:11453 ENTREZGENE
Human Proteome Map SULT1A1 Human Proteome Map
InterPro Mpv17_PMP22 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6817 UniProtKB/Swiss-Prot
NCBI Gene 6817 ENTREZGENE
OMIM 171150 OMIM
PANTHER PTHR11266 UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA343 PharmGKB, RGD
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7I2V2T5_HUMAN UniProtKB/TrEMBL
  A0A7I2YQ64_HUMAN UniProtKB/TrEMBL
  H3BMH9_HUMAN UniProtKB/TrEMBL
  H3BQX5_HUMAN UniProtKB/TrEMBL
  H3BRY5_HUMAN UniProtKB/TrEMBL
  H3BT96_HUMAN UniProtKB/TrEMBL
  P50225 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q2NL71 UniProtKB/Swiss-Prot
  Q86U58 UniProtKB/Swiss-Prot
  Q92818 UniProtKB/Swiss-Prot
  Q9BVU6 UniProtKB/Swiss-Prot
  Q9UGG7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-07 SULT1A1  sulfotransferase family 1A member 1  AC020765.6  novel protein  Data Merged 737654 PROVISIONAL
2021-02-23 AC020765.6  novel protein  AC020765.6  Sulfotransferase 1A1  Symbol and/or name change 19259462 PROVISIONAL
2015-11-10 SULT1A1  sulfotransferase family 1A member 1    sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1  Symbol and/or name change 5135510 APPROVED