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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735435
Species: Homo sapiens
RGD Object: Gene
Symbol: SULT1A1
Name: sulfotransferase family 1A member 1
Acc ID: CHEBI:183848
Term: 1-Methylpyrene
Definition: null
Chemical ID: MESH:C053035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SULT1A1multiple interactionsEXP 6480464CTD1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]; [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene; [CYP1A2 protein co-treated with SULT1A1 protein] results in increased susceptibility to 1-methylpyrene; [SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene; Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]PMID:25243916 PMID:27913846 PMID:33035519
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