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Gene: Fez1 (fasciculation and elongation protein zeta 1) Rattus norvegicus
Symbol: Fez1
Name: fasciculation and elongation protein zeta 1
RGD ID: 619708
Description: Exhibits protein N-terminus binding activity and protein kinase C binding activity. Involved in several processes, including mitochondrion morphogenesis; nervous system development; and positive regulation of anterograde axonal transport of mitochondrion. Localizes to several cellular components, including dendrite; growth cone; and neuronal cell body. Colocalizes with mitochondrion. Biomarker of Parkinson's disease. Orthologous to human FEZ1 (fasciculation and elongation protein zeta 1); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; ammonium chloride.
Type: protein-coding
Also known as: fasciculation and elongation protein zeta 1 (zygin I); fasciculation and elongation protein zeta-1; MGC105385; protein kinase C-binding protein Zeta1; zygin I; zygin-1
Homo sapiens (human) : FEZ1 (fasciculation and elongation protein zeta 1)  HGNC  Alliance
Mus musculus (house mouse) : Fez1 (fasciculation and elongation protein zeta 1 (zygin I))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fez1 (fasciculation and elongation protein zeta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FEZ1 (fasciculation and elongation protein zeta 1)
Canis lupus familiaris (dog) : FEZ1 (fasciculation and elongation protein zeta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fez1 (fasciculation and elongation protein zeta 1)
Sus scrofa (pig) : FEZ1 (fasciculation and elongation protein zeta 1)
Chlorocebus sabaeus (African green monkey) : FEZ1 (fasciculation and elongation protein zeta 1)
Heterocephalus glaber (naked mole-rat) : Fez1 (fasciculation and elongation protein zeta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0839,305,128 - 39,350,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,305,128 - 39,350,270 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,307,579 - 39,353,313 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,078,328 - 38,123,983 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1838,087,093 - 38,132,749 (+)NCBI
Celera837,851,976 - 37,897,230 (-)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fez1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619708
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.