Arfgef1 (ADP ribosylation factor guanine nucleotide exchange factor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Arfgef1 (ADP ribosylation factor guanine nucleotide exchange factor 1) Mus musculus
Analyze
Symbol: Arfgef1
Name: ADP ribosylation factor guanine nucleotide exchange factor 1
RGD ID: 1615720
MGI Page MGI
Description: Predicted to enable guanyl-nucleotide exchange factor activity; myosin binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including negative regulation of GTPase activity; negative regulation of actin filament polymerization; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to act upstream of with a positive effect on protein glycosylation. Predicted to be located in several cellular components, including Golgi apparatus; nuclear lumen; and perinuclear region of cytoplasm. Predicted to be part of small nuclear ribonucleoprotein complex. Is expressed in brain. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor guanine nucleotide-exchange factor 1; ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited); ARFG; ARFGEP1; BIG; BIG1; brefeldin A-inhibited GEP 1; brefeldin A-inhibited guanine nucleotide-exchange protein 1; D130059B05Rik; D730028O18Rik; P20; P200
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39110,207,732 - 10,303,306 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl110,207,796 - 10,302,895 (-)EnsemblGRCm39 Ensembl
GRCm38110,137,507 - 10,232,670 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl110,137,571 - 10,232,670 (-)EnsemblGRCm38mm10GRCm38
MGSCv37110,127,588 - 10,222,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36110,122,721 - 10,218,159 (-)NCBIMGSCv36mm8
Celera110,111,100 - 10,206,279 (-)NCBICelera
Cytogenetic Map1A2NCBI
cM Map12.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:16141072   PMID:16141073   PMID:18579678   PMID:18799693  
PMID:21873635   PMID:23386609   PMID:24948604   PMID:27568566   PMID:28414797   PMID:29740613   PMID:30674481   PMID:31678406   PMID:32325033   PMID:34153089   PMID:38355793  


Genomics

Comparative Map Data
Arfgef1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39110,207,732 - 10,303,306 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl110,207,796 - 10,302,895 (-)EnsemblGRCm39 Ensembl
GRCm38110,137,507 - 10,232,670 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl110,137,571 - 10,232,670 (-)EnsemblGRCm38mm10GRCm38
MGSCv37110,127,588 - 10,222,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36110,122,721 - 10,218,159 (-)NCBIMGSCv36mm8
Celera110,111,100 - 10,206,279 (-)NCBICelera
Cytogenetic Map1A2NCBI
cM Map12.36NCBI
ARFGEF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38867,173,511 - 67,343,781 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl867,173,511 - 67,343,781 (-)EnsemblGRCh38hg38GRCh38
GRCh37868,085,746 - 68,256,016 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36868,272,451 - 68,418,466 (-)NCBINCBI36Build 36hg18NCBI36
Build 34868,272,450 - 68,418,466NCBI
Celera864,103,297 - 64,249,319 (-)NCBICelera
Cytogenetic Map8q13.2NCBI
HuRef863,601,813 - 63,748,371 (-)NCBIHuRef
CHM1_1868,165,896 - 68,311,968 (-)NCBICHM1_1
T2T-CHM13v2.0867,599,967 - 67,770,273 (-)NCBIT2T-CHM13v2.0
Arfgef1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8513,764,507 - 13,859,237 (+)NCBIGRCr8
mRatBN7.258,982,061 - 9,076,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl58,981,540 - 9,076,326 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx511,137,964 - 11,230,261 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0512,761,387 - 12,855,480 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0512,472,621 - 12,564,922 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.058,666,046 - 8,760,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl58,666,200 - 8,760,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0513,474,381 - 13,568,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.458,498,644 - 8,592,918 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera58,494,495 - 8,587,878 (+)NCBICelera
Cytogenetic Map5q11NCBI
Arfgef1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544411,986,595 - 12,110,172 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544411,986,595 - 12,110,172 (+)NCBIChiLan1.0ChiLan1.0
ARFGEF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2782,934,778 - 83,078,661 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1858,577,096 - 58,720,869 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0863,740,512 - 63,884,189 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1865,402,117 - 65,546,014 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl865,403,386 - 65,545,789 (-)Ensemblpanpan1.1panPan2
ARFGEF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12916,712,872 - 16,852,478 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2916,708,820 - 16,852,844 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2917,028,251 - 17,168,331 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02916,793,854 - 16,933,903 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2916,793,352 - 16,934,175 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12916,825,243 - 16,966,723 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02916,925,119 - 17,065,181 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02917,182,796 - 17,322,945 (-)NCBIUU_Cfam_GSD_1.0
Arfgef1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530367,870,517 - 67,978,189 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364966,807,403 - 6,914,987 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364966,807,388 - 6,914,960 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARFGEF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl467,465,529 - 67,613,611 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1467,465,517 - 67,613,611 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2473,526,804 - 73,674,463 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARFGEF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1863,058,504 - 63,204,238 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl863,057,200 - 63,204,292 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603978,298,523 - 78,446,510 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arfgef1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474424,011,136 - 24,143,202 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474424,010,609 - 24,144,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:581
Count of miRNA genes:393
Interacting mature miRNAs:464
Transcripts:ENSMUST00000088615, ENSMUST00000128834, ENSMUST00000131556, ENSMUST00000142497, ENSMUST00000156563
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301011Cplaq4_mcircadian period of locomotor activity 4 (mouse)Not determined1967344243673601Mouse
1301275Sle10_msystematic lupus erythematosus susceptibility 10 (mouse)Not determined1288219436882352Mouse
15092046Wngrme1_mweek nine growth rate, maternal effect 1 (mouse)1328014237782236Mouse
1301370Adip1_madiposity 1 (mouse)Not determined1288219436882352Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
15092044Wtgrme1_mweek ten growth rate, maternal effect 1 (mouse)1328014237782236Mouse
1301471Obq2_mobesity QTL 2 (mouse)Not determined1394162037941887Mouse
1301891Alcp25_malcohol preference locus 25 (mouse)Not determined1125203185Mouse
1300834Cia20_mcollagen induced arthritis 20 (mouse)Not determined1125203185Mouse
15092055Lgrme1_mlate growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092050Wsegrme1_mweek seven growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092051Wegrme1_mweek eight growth rate, maternal effect 1 (mouse)1328014237782236Mouse
15092048Wsigrme1_mweek six growth rate, maternal effect 1 (mouse)1328014237782236Mouse
1301482Morph1_mmorphine antinociception 1 (mouse)Not determined1130367747Mouse
10043970Obq23_mobesity QTL 23 (mouse)Not determined1501266539012665Mouse
10412226Alpq4_malcohol preference QTL 4 (mouse)Not determined1122976684Mouse

Markers in Region
03.MMHAP85FLA3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38110,228,173 - 10,228,343UniSTSGRCm38
MGSCv37110,218,254 - 10,218,424UniSTSGRCm37
Celera110,201,782 - 10,201,952UniSTS
Cytogenetic Map1A2UniSTS
Whitehead_YAC1 UniSTS
D5Mit392.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A3UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map6F1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic MapXF5UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic MapXF3UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map13A3.1UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map2E1UniSTS
cM Map528.0UniSTS
Whitehead Genetic518.6UniSTS
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000088615   ⟹   ENSMUSP00000085986
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,207,796 - 10,302,895 (-)Ensembl
GRCm38.p6 Ensembl110,137,571 - 10,232,670 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,230,982 - 10,231,531 (-)Ensembl
GRCm38.p6 Ensembl110,160,757 - 10,161,306 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131556   ⟹   ENSMUSP00000118805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,243,300 - 10,302,895 (-)Ensembl
GRCm38.p6 Ensembl110,173,075 - 10,232,670 (-)Ensembl
Ensembl Acc Id: ENSMUST00000142497
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,217,630 - 10,224,755 (-)Ensembl
GRCm38.p6 Ensembl110,147,405 - 10,154,530 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156563
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,226,624 - 10,230,285 (-)Ensembl
GRCm38.p6 Ensembl110,156,399 - 10,160,060 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186720
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,279,386 - 10,284,438 (-)Ensembl
GRCm38.p6 Ensembl110,209,161 - 10,214,213 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186813
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,279,171 - 10,280,332 (-)Ensembl
GRCm38.p6 Ensembl110,208,946 - 10,210,107 (-)Ensembl
Ensembl Acc Id: ENSMUST00000187417
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl110,208,915 - 10,211,926 (-)Ensembl
GRCm38.p6 Ensembl110,138,690 - 10,141,701 (-)Ensembl
RefSeq Acc Id: NM_001102430   ⟹   NP_001095900
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39110,207,732 - 10,302,895 (-)NCBI
GRCm38110,137,507 - 10,232,670 (-)NCBI
MGSCv37110,127,588 - 10,222,751 (-)RGD
Celera110,111,100 - 10,206,279 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_004941387
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39110,207,795 - 10,303,306 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001095900 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH25221 (Get FASTA)   NCBI Sequence Viewer  
  BAC34685 (Get FASTA)   NCBI Sequence Viewer  
  EDL14306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000085986
  ENSMUSP00000085986.5
  ENSMUSP00000118805.2
GenBank Protein G3X9K3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001095900   ⟸   NM_001102430
- UniProtKB: Q8BKL2 (UniProtKB/Swiss-Prot),   G3X9K3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000085986   ⟸   ENSMUST00000088615
Ensembl Acc Id: ENSMUSP00000118805   ⟸   ENSMUST00000131556
Protein Domains
SEC7   Sec7/BIG1-like C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3X9K3-F1-model_v2 AlphaFold G3X9K3 1-1846 view protein structure

Promoters
RGD ID:6873182
Promoter ID:EPDNEW_M42
Type:single initiation site
Name:Arfgef1_1
Description:Mus musculus ADP-ribosylation factor guanine nucleotide-exchangefactor 1(brefeldin A-inhibited) , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38110,216,563 - 10,216,623EPDNEW
RGD ID:6817369
Promoter ID:MM_KWN:114
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:NM_001102430,   OTTMUST00000085576
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36110,222,376 - 10,223,217 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442988 AgrOrtholog
Ensembl Genes ENSMUSG00000067851 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000088615 ENTREZGENE
  ENSMUST00000088615.11 UniProtKB/Swiss-Prot
  ENSMUST00000131556.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1000.11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.220.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/Swiss-Prot
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DCB_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7/BIG1-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_C UniProtKB/Swiss-Prot
  Sec7_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:211673 UniProtKB/Swiss-Prot
MGD MGI:2442988 ENTREZGENE
NCBI Gene Arfgef1 ENTREZGENE
PANTHER BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GUANYL-NUCLEOTIDE EXCHANGE FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BIG2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DCB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1981 UniProtKB/Swiss-Prot
  Sec7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arfgef1 PhenoGen
PROSITE SEC7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Sec7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48425 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt BIG1_MOUSE UniProtKB/Swiss-Prot
  D3YYK9_MOUSE UniProtKB/TrEMBL
  G3X9K3 ENTREZGENE
  Q8BKL2 ENTREZGENE
  Q8R3I7_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q8BKL2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Arfgef1  ADP ribosylation factor guanine nucleotide exchange factor 1  D130059B05Rik  RIKEN cDNA D130059B05 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 D130059B05Rik  RIKEN cDNA D130059B05 gene  Arfgef1  ADP ribosylation factor guanine nucleotide exchange factor 1  Symbol and/or name change 5135510 APPROVED
2023-07-04 Arfgef1  ADP ribosylation factor guanine nucleotide exchange factor 1  Arfgef1  ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)  Symbol and/or name change 5135510 APPROVED