CDC5L (cell division cycle 5 like) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CDC5L (cell division cycle 5 like) Sus scrofa
Analyze
Symbol: CDC5L
Name: cell division cycle 5 like
RGD ID: 14042809
Description: ENCODES a protein that exhibits leucine zipper domain binding (ortholog); protein kinase binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to fibroblast growth factor stimulus (ortholog); cellular response to interleukin-2 (ortholog); cellular response to nerve growth factor stimulus (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH CAKUT (ortholog); esophagus adenocarcinoma (ortholog); Lung Neoplasms (ortholog); FOUND IN nuclear speck (ortholog); perinuclear region of cytoplasm (ortholog); protein-DNA complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cell division cycle 5-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,384,556 - 39,431,248 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,384,397 - 39,427,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,306,065 - 45,349,669 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CDC5LPigesophagus adenocarcinoma disease_progressionISOCDC5L (Homo sapiens)9068941protein:increased expression:esophageal mucosa (human)RGDPMID:15725809 and REF_RGD_ID:10047052
CDC5LPigLung Neoplasms  ISOCdc5l (Mus musculus)9068941mRNA:increased expression:lung (mouse)RGDPMID:14647414 and REF_RGD_ID:10047051
CDC5LPigosteosarcoma  ISOCDC5L (Homo sapiens)9068941DNA:amplification:cds (human)RGDPMID:18567798 and REF_RGD_ID:10047050
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CDC5LPigCAKUT  ISOCDC5L (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital anomalies of kidney and urinary tractClinVarPMID:27657687


Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CDC5LPigcell division involved_inIEAUniProtKB-KW:KW-0132150520179 UniProtGO_REF:0000043
CDC5LPigcellular response to fibroblast growth factor stimulus  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:11694351 and REF_RGD_ID:10047049
CDC5LPigcellular response to interleukin-2  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:11694351 and REF_RGD_ID:10047049
CDC5LPigcellular response to nerve growth factor stimulus  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:20629186 and REF_RGD_ID:10045890
CDC5LPigcellular response to prolactin  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:9296381 and REF_RGD_ID:61637
CDC5LPigcellular response to wortmannin  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:20629186 and REF_RGD_ID:10045890
CDC5LPigDNA damage checkpoint signaling involved_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigmRNA processing involved_inIEAUniProtKB-KW:KW-0507150520179 UniProtGO_REF:0000043
CDC5LPigmRNA splicing, via spliceosome involved_inIBAPANTHER:PTN000067719 more ...150520179 GO_CentralGO_REF:0000033
CDC5LPigmRNA splicing, via spliceosome involved_inIEAInterPro:IPR047242150520179 InterProGO_REF:0000002
CDC5LPigmRNA splicing, via spliceosome involved_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigregulation of transcription by RNA polymerase II involved_inIBAPANTHER:PTN000836844 and UniProtKB:Q99459150520179 GO_CentralGO_REF:0000033
CDC5LPigRNA splicing involved_inIEAUniProtKB-KW:KW-0508150520179 UniProtGO_REF:0000043
1 to 14 of 14 rows

Cellular Component
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CDC5LPigcatalytic step 2 spliceosome part_ofIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigcytoplasm part_ofIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigDNA replication factor A complex located_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPignuclear speck  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:11884640 and REF_RGD_ID:619664
CDC5LPignuclear speck located_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPignucleoplasm located_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPignucleus located_inIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPignucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
CDC5LPigperinuclear region of cytoplasm  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:11694351 and REF_RGD_ID:10047049
CDC5LPigprotein-DNA complex  ISOCdc5l (Rattus norvegicus)9068941 RGDPMID:11694351 and REF_RGD_ID:10047049
CDC5LPigPrp19 complex part_ofIBAFB:FBgn0265574 more ...150520179 GO_CentralGO_REF:0000033
CDC5LPigPrp19 complex part_ofIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigPrp19 complex part_ofIEAInterPro:IPR047242150520179 InterProGO_REF:0000002
CDC5LPigspliceosomal complex part_ofIBAPANTHER:PTN000067719 more ...150520179 GO_CentralGO_REF:0000033
CDC5LPigspliceosomal complex part_ofIEAUniProtKB-KW:KW-0747150520179 UniProtGO_REF:0000043
CDC5LPigspliceosomal complex part_ofIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigU2-type catalytic step 2 spliceosome part_ofIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
1 to 17 of 17 rows

Molecular Function
1 to 20 of 31 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CDC5LPigDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAPANTHER:PTN000836844 and UniProtKB:Q99459150520179 GO_CentralGO_REF:0000033
CDC5LPigidentical protein binding enablesIEAUniProtKB:Q99459 and ensembl:ENSP00000360532150520179 EnsemblGO_REF:0000107
CDC5LPigleucine zipper domain binding  ISODapk3 (Rattus norvegicus)9068941 RGDPMID:11884640 and REF_RGD_ID:619664
CDC5LPigprotein binding enablesISOUniProtKB:Q9UNY49068941 PMID:12927788IntActPMID:12927788
CDC5LPigprotein binding enablesISOUniProtKB:P079109068941 PMID:39251607IntActPMID:39251607
CDC5LPigprotein binding enablesISOUniProtKB:Q08379 and UniProtKB:Q0D2H99068941 PMID:25416956IntActPMID:25416956
CDC5LPigprotein binding enablesISOUniProtKB:Q13535 and UniProtKB:Q9UMS49068941 PMID:19633697IntActPMID:19633697
CDC5LPigprotein binding enablesISOUniProtKB:O75934 and UniProtKB:P079109068941 PMID:30021884IntActPMID:30021884
CDC5LPigprotein binding enablesISOUniProtKB:P621369068941 PMID:22940584IntActPMID:22940584
CDC5LPigprotein binding enablesISOUniProtKB:O60341 more ...9068941 PMID:17043677 and PMID:31413325IntActPMID:17043677 and PMID:31413325
CDC5LPigprotein binding enablesISOUniProtKB:O43660 more ...9068941 PMID:20176811UniProtPMID:20176811
CDC5LPigprotein binding enablesISOUniProtKB:Q9UMS49068941 PMID:28514442IntActPMID:28514442
CDC5LPigprotein binding enablesISOUniProtKB:O759349068941 PMID:22365833IntActPMID:22365833
CDC5LPigprotein binding enablesISOUniProtKB:O43660 more ...9068941 PMID:20467437IntActPMID:20467437
CDC5LPigprotein binding enablesISOUniProtKB:Q8WYA69068941 PMID:18722174 and PMID:24269683IntActPMID:18722174 and PMID:24269683
CDC5LPigprotein binding enablesISOUniProtKB:O95751 more ...9068941 PMID:32296183IntActPMID:32296183
CDC5LPigprotein binding enablesISOUniProtKB:O43660 more ...9068941 PMID:20176811IntActPMID:20176811
CDC5LPigprotein binding enablesISOUniProtKB:Q134169068941 PMID:15232106IntActPMID:15232106
CDC5LPigprotein binding enablesISOUniProtKB:Q154289068941 PMID:17332742IntActPMID:17332742
1 to 20 of 31 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CDC5LPigspliceosome pathway   ISOCDC5L (Homo sapiens)9068941 RGDPMID:23742842 and REF_RGD_ID:9686094
PMID:14681463   PMID:30032202  



CDC5L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,384,556 - 39,431,248 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,384,397 - 39,427,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,306,065 - 45,349,669 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC5L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,387,706 - 44,450,425 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,387,706 - 44,450,425 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,355,443 - 44,418,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,463,280 - 44,522,758 (+)NCBINCBI36Build 36hg18NCBI36
Build 34644,463,279 - 44,522,757NCBI
Celera645,908,480 - 45,967,835 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef644,077,869 - 44,140,670 (+)NCBIHuRef
CHM1_1644,358,890 - 44,421,686 (+)NCBICHM1_1
T2T-CHM13v2.0644,222,452 - 44,285,059 (+)NCBIT2T-CHM13v2.0
Cdc5l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,702,809 - 45,744,633 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,702,810 - 45,744,663 (-)EnsemblGRCm39 Ensembl
GRCm381745,391,887 - 45,433,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,391,884 - 45,433,737 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,528,836 - 45,570,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361744,855,468 - 44,897,288 (-)NCBIMGSCv36mm8
Celera1748,822,530 - 48,866,019 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.36NCBI
Cdc5l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8923,062,397 - 23,100,901 (+)NCBIGRCr8
mRatBN7.2915,564,949 - 15,603,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,564,767 - 15,603,450 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,151,506 - 24,189,633 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,214,190 - 29,252,317 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,514,951 - 27,553,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,949,764 - 17,988,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,949,764 - 17,988,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,838,171 - 16,876,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,165,631 - 11,204,135 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,162,952 - 11,201,455 (+)NCBI
Celera913,308,462 - 13,346,957 (+)NCBICelera
Cytogenetic Map9q12NCBI
Cdc5l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,990,613 - 10,032,034 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,990,613 - 10,032,034 (+)NCBIChiLan1.0ChiLan1.0
CDC5L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,891,113 - 58,955,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,761,126 - 54,821,533 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,983,840 - 44,043,029 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,265,845 - 45,326,392 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,265,845 - 45,326,383 (+)Ensemblpanpan1.1panPan2
CDC5L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,779,936 - 12,822,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,780,010 - 12,822,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,807,973 - 12,851,031 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,266,108 - 13,309,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,266,132 - 13,309,158 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,791,651 - 12,835,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,879,429 - 12,922,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,973,455 - 13,016,504 (+)NCBIUU_Cfam_GSD_1.0
Cdc5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,262,000 - 48,311,662 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,648,678 - 15,698,106 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,647,470 - 15,698,095 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC5L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,727,185 - 27,785,233 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,722,819 - 27,785,268 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,437,105 - 44,495,930 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc5l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,477,193 - 15,517,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,477,188 - 15,517,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in CDC5L
916 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3



Ensembl Acc Id: ENSSSCT00000001908   ⟹   ENSSSCP00000001861
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,384,556 - 39,431,248 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000097365   ⟹   ENSSSCP00000080432
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,387,243 - 39,431,248 (+)Ensembl
RefSeq Acc Id: XM_001929597   ⟹   XP_001929632
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1739,384,397 - 39,427,729 (+)NCBI
Sequence:
RefSeq Acc Id: XP_001929632   ⟸   XM_001929597
- UniProtKB: F1RQS5 (UniProtKB/TrEMBL),   A0A4X1V455 (UniProtKB/TrEMBL),   A0A8D0KGE9 (UniProtKB/TrEMBL),   A0A8W4FLS6 (UniProtKB/TrEMBL),   A0A8D0USH3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000001861   ⟸   ENSSSCT00000001908
Ensembl Acc Id: ENSSSCP00000080432   ⟸   ENSSSCT00000097365
HTH myb-type   Myb-like



1 to 40 of 52 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000001708 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015027281 UniProtKB/TrEMBL
  ENSSSCG00025044697 UniProtKB/TrEMBL
  ENSSSCG00030066772 UniProtKB/TrEMBL
  ENSSSCG00035078764 UniProtKB/TrEMBL
  ENSSSCG00040064466 UniProtKB/TrEMBL
  ENSSSCG00045020282 UniProtKB/TrEMBL
  ENSSSCG00050003999 UniProtKB/TrEMBL
  ENSSSCG00055015957 UniProtKB/TrEMBL
  ENSSSCG00060020538 UniProtKB/TrEMBL
  ENSSSCG00065067867 UniProtKB/TrEMBL
  ENSSSCG00070021750 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001908 ENTREZGENE
  ENSSSCT00000001908.4 UniProtKB/TrEMBL
  ENSSSCT00000097365.1 UniProtKB/TrEMBL
  ENSSSCT00015036453.1 UniProtKB/TrEMBL
  ENSSSCT00025060925.1 UniProtKB/TrEMBL
  ENSSSCT00030093390.1 UniProtKB/TrEMBL
  ENSSSCT00035107597.1 UniProtKB/TrEMBL
  ENSSSCT00040088275.1 UniProtKB/TrEMBL
  ENSSSCT00045034780.1 UniProtKB/TrEMBL
  ENSSSCT00045034913.1 UniProtKB/TrEMBL
  ENSSSCT00050005474.1 UniProtKB/TrEMBL
  ENSSSCT00055031588.1 UniProtKB/TrEMBL
  ENSSSCT00055031682.1 UniProtKB/TrEMBL
  ENSSSCT00060027849.1 UniProtKB/TrEMBL
  ENSSSCT00065093230.1 UniProtKB/TrEMBL
  ENSSSCT00070043218.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro CDC5L/Cef1 UniProtKB/TrEMBL
  Cdc5p/Cef1 UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Myb_dom UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SANT_CDC5L_II UniProtKB/TrEMBL
KEGG Report ssc:100153900 UniProtKB/TrEMBL
NCBI Gene CDC5L ENTREZGENE
PANTHER CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/TrEMBL
  CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Myb_Cef UniProtKB/TrEMBL
1 to 40 of 52 rows