CDC5L (cell division cycle 5 like) - Rat Genome Database

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Gene: CDC5L (cell division cycle 5 like) Canis lupus familiaris
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Symbol: CDC5L
Name: cell division cycle 5 like
RGD ID: 12296558
Description: ENCODES a protein that exhibits leucine zipper domain binding (ortholog); protein kinase binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to fibroblast growth factor stimulus (ortholog); cellular response to interleukin-2 (ortholog); cellular response to nerve growth factor stimulus (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH CAKUT (ortholog); esophagus adenocarcinoma (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); DNA replication factor A complex (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CDC5 cell division cycle 5-like; cell division cycle 5-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,779,936 - 12,822,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,780,010 - 12,822,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,807,973 - 12,851,031 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,266,108 - 13,309,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,266,132 - 13,309,158 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,791,651 - 12,835,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,879,429 - 12,922,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,973,455 - 13,016,504 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CDC5L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,779,936 - 12,822,978 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,780,010 - 12,822,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,807,973 - 12,851,031 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,266,108 - 13,309,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,266,132 - 13,309,158 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,791,651 - 12,835,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,879,429 - 12,922,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,973,455 - 13,016,504 (+)NCBIUU_Cfam_GSD_1.0
CDC5L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,387,706 - 44,450,425 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,387,706 - 44,450,425 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,355,443 - 44,418,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,463,280 - 44,522,758 (+)NCBINCBI36Build 36hg18NCBI36
Build 34644,463,279 - 44,522,757NCBI
Celera645,908,480 - 45,967,835 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef644,077,869 - 44,140,670 (+)NCBIHuRef
CHM1_1644,358,890 - 44,421,686 (+)NCBICHM1_1
T2T-CHM13v2.0644,222,452 - 44,285,059 (+)NCBIT2T-CHM13v2.0
Cdc5l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,702,809 - 45,744,633 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,702,810 - 45,744,663 (-)EnsemblGRCm39 Ensembl
GRCm381745,391,887 - 45,433,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,391,884 - 45,433,737 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,528,836 - 45,570,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361744,855,468 - 44,897,288 (-)NCBIMGSCv36mm8
Celera1748,822,530 - 48,866,019 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.36NCBI
Cdc5l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8923,062,397 - 23,100,901 (+)NCBIGRCr8
mRatBN7.2915,564,949 - 15,603,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,564,767 - 15,603,450 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,151,506 - 24,189,633 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,214,190 - 29,252,317 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,514,951 - 27,553,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,949,764 - 17,988,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,949,764 - 17,988,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,838,171 - 16,876,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,165,631 - 11,204,135 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,162,952 - 11,201,455 (+)NCBI
Celera913,308,462 - 13,346,957 (+)NCBICelera
Cytogenetic Map9q12NCBI
Cdc5l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,990,613 - 10,032,034 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,990,613 - 10,032,034 (+)NCBIChiLan1.0ChiLan1.0
CDC5L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,891,113 - 58,955,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,761,126 - 54,821,533 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,983,840 - 44,043,029 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,265,845 - 45,326,392 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,265,845 - 45,326,383 (+)Ensemblpanpan1.1panPan2
Cdc5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,262,000 - 48,311,662 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,648,678 - 15,698,106 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,647,470 - 15,698,095 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC5L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,384,556 - 39,431,248 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,384,397 - 39,427,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,306,065 - 45,349,669 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC5L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,727,185 - 27,785,233 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,722,819 - 27,785,268 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,437,105 - 44,495,930 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc5l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,477,193 - 15,517,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,477,188 - 15,517,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDC5L
509 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 13 1 6 12 8 10 4
Low 2 5 9 6 5 6 6 2
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000003163   ⟹   ENSCAFP00000002938
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1212,780,010 - 12,822,801 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845021320   ⟹   ENSCAFP00845016768
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1213,266,132 - 13,309,158 (+)Ensembl
RefSeq Acc Id: XM_038491950   ⟹   XP_038347878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11212,791,651 - 12,835,010 (+)NCBI
RefSeq Acc Id: XM_038554212   ⟹   XP_038410140
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01212,973,455 - 13,016,504 (+)NCBI
RefSeq Acc Id: XM_038618079   ⟹   XP_038474007
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01212,879,429 - 12,922,495 (+)NCBI
RefSeq Acc Id: XM_038683676   ⟹   XP_038539604
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01213,266,108 - 13,309,161 (+)NCBI
RefSeq Acc Id: XM_532156   ⟹   XP_532156
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11212,779,936 - 12,822,978 (+)NCBI
Dog10K_Boxer_Tasha1212,807,973 - 12,851,031 (+)NCBI
Sequence:
RefSeq Acc Id: XP_532156   ⟸   XM_532156
- UniProtKB: A0A8C0YW82 (UniProtKB/TrEMBL),   A0A8C0KHH7 (UniProtKB/TrEMBL),   A0A8I3NKY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000002938   ⟸   ENSCAFT00000003163
RefSeq Acc Id: XP_038347878   ⟸   XM_038491950
RefSeq Acc Id: XP_038474007   ⟸   XM_038618079
RefSeq Acc Id: XP_038539604   ⟸   XM_038683676
- UniProtKB: A0A8C0YW82 (UniProtKB/TrEMBL),   A0A8C0KHH7 (UniProtKB/TrEMBL),   A0A8I3NKY0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410140   ⟸   XM_038554212
- UniProtKB: A0A8C0KHH7 (UniProtKB/TrEMBL),   A0A8C0YW82 (UniProtKB/TrEMBL),   A0A8I3NKY0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845016768   ⟸   ENSCAFT00845021320
Protein Domains
HTH myb-type   Myb-like

Promoters
RGD ID:13685447
Promoter ID:EPDNEW_C3516
Type:multiple initiation site
Name:CDC5L_1
Description:cell division cycle 5 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11212,779,957 - 12,780,017EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001996 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030007920 UniProtKB/TrEMBL
  ENSCAFG00040011753 UniProtKB/TrEMBL
  ENSCAFG00845011982 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003163.5 UniProtKB/TrEMBL
  ENSCAFT00030014561.1 UniProtKB/TrEMBL
  ENSCAFT00040021676.1 UniProtKB/TrEMBL
  ENSCAFT00845021320 ENTREZGENE
  ENSCAFT00845021320.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro CDC5L/Cef1 UniProtKB/TrEMBL
  Cdc5p/Cef1_C UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Myb_dom UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SANT_CDC5L_II UniProtKB/TrEMBL
KEGG Report cfa:474921 UniProtKB/TrEMBL
NCBI Gene CDC5L ENTREZGENE
PANTHER CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/TrEMBL
  CELL DIVISION CYCLE 5-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Myb_Cef UniProtKB/TrEMBL
  Myb_DNA-bind_6 UniProtKB/TrEMBL
PROSITE HTH_MYB UniProtKB/TrEMBL
  MYB_LIKE UniProtKB/TrEMBL
SMART SANT UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C0KHH7 ENTREZGENE
  A0A8C0YW82 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NKY0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39008 ENTREZGENE