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Gene: Kmt5c (lysine methyltransferase 5C) Rattus norvegicus
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Symbol: Kmt5c
Name: lysine methyltransferase 5C
Description: Predicted to have several functions, including S-adenosyl-L-methionine binding activity; histone binding activity; and histone methyltransferase activity (H4-K20 specific). Predicted to be involved in DNA repair; histone H4-K20 trimethylation; and positive regulation of DNA metabolic process. Predicted to localize to nuclear lumen and pericentric heterochromatin. Biomarker of liver benign neoplasm. Orthologous to human KMT5C (lysine methyltransferase 5C); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: [histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; LOC308345; lysine (K)-specific methyltransferase 5C; lysine-specific methyltransferase 5C; su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); suv4-20h2; Suv420h2
Orthologs:
Homo sapiens (human) : KMT5C (lysine methyltransferase 5C)  HGNC  Alliance
Mus musculus (house mouse) : Kmt5c (lysine methyltransferase 5C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt5c (lysine methyltransferase 5C)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT5C (lysine methyltransferase 5C)
Canis lupus familiaris (dog) : KMT5C (lysine methyltransferase 5C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt5c (lysine methyltransferase 5C)
Sus scrofa (pig) : KMT5C (lysine methyltransferase 5C)
Chlorocebus sabaeus (African green monkey) : KMT5C (lysine methyltransferase 5C)
Heterocephalus glaber (naked mole-rat) : Kmt5c (lysine methyltransferase 5C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0172,666,662 - 72,674,271 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,666,665 - 72,674,271 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,861,337 - 75,868,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,815,981 - 67,823,611 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1167,894,088 - 67,899,997 (-)NCBI
Celera168,017,407 - 68,024,973 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kmt5c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305226
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.