Kmt5c (lysine methyltransferase 5C) - Rat Genome Database

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Gene: Kmt5c (lysine methyltransferase 5C) Ictidomys tridecemlineatus
Analyze
Symbol: Kmt5c
Name: lysine methyltransferase 5C
RGD ID: 12725622
Description: ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone H4K20 methyltransferase activity (inferred); INVOLVED IN chromatin remodeling (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); genetic disease (ortholog); liver benign neoplasm (ortholog); FOUND IN condensed chromosome, centromeric region (inferred); heterochromatin (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,956,266 - 1,963,342 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886595,782 - 604,286 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936886596,949 - 602,959 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kmt5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,956,266 - 1,963,342 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886595,782 - 604,286 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936886596,949 - 602,959 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KMT5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,339,876 - 55,348,121 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,339,853 - 55,348,121 (+)EnsemblGRCh38hg38GRCh38
GRCh371955,851,244 - 55,859,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,543,076 - 60,551,301 (+)NCBINCBI36Build 36hg18NCBI36
Build 341960,543,075 - 60,551,300NCBI
Celera1952,892,173 - 52,900,453 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,173,507 - 52,181,789 (+)NCBIHuRef
CHM1_11955,845,041 - 55,853,309 (+)NCBICHM1_1
T2T-CHM13v2.01958,435,095 - 58,443,627 (+)NCBIT2T-CHM13v2.0
Kmt5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,743,091 - 4,750,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,743,114 - 4,750,513 (+)EnsemblGRCm39 Ensembl
GRCm3874,740,092 - 4,747,514 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,740,115 - 4,747,514 (+)EnsemblGRCm38mm10GRCm38
MGSCv3774,691,729 - 4,699,116 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,343,275 - 4,350,574 (+)NCBIMGSCv36mm8
Celera74,470,199 - 4,477,587 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.74NCBI
Kmt5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,128,325 - 78,135,931 (-)NCBIGRCr8
mRatBN7.2169,099,531 - 69,107,145 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,099,539 - 69,107,145 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,444,576 - 74,452,182 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,008,879 - 83,016,485 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,157,538 - 76,165,177 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,666,662 - 72,674,271 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,666,665 - 72,674,271 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,861,337 - 75,868,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,815,981 - 67,823,611 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,894,088 - 67,899,997 (-)NCBI
Celera168,017,407 - 68,024,973 (+)NCBICelera
Cytogenetic Map1q12NCBI
Kmt5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567894,608 - 900,578 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955567895,334 - 901,240 (-)NCBIChiLan1.0ChiLan1.0
KMT5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,476,795 - 61,485,754 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,205,884 - 63,214,838 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,381,963 - 52,390,507 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,073,185 - 61,079,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,073,396 - 61,078,717 (+)Ensemblpanpan1.1panPan2
KMT5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,334,687 - 102,342,090 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,333,543 - 102,342,118 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,391,254 - 102,398,667 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01102,987,756 - 102,995,170 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,986,612 - 102,995,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,625,010 - 102,632,419 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,337,091 - 102,344,516 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,100,299 - 103,107,712 (-)NCBIUU_Cfam_GSD_1.0
KMT5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,517,098 - 59,524,550 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,517,058 - 59,524,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KMT5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,942,100 - 47,950,364 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,944,197 - 47,949,693 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045576,523 - 584,848 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kmt5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,945,193 - 1,951,247 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,945,194 - 1,951,016 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000679   ⟹   ENSSTOP00000000609
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936886595,782 - 604,286 (+)Ensembl
RefSeq Acc Id: XM_040279916   ⟹   XP_040135850
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244093491,956,266 - 1,962,302 (-)NCBI
RefSeq Acc Id: XM_040279917   ⟹   XP_040135851
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244093491,956,266 - 1,962,302 (-)NCBI
RefSeq Acc Id: XM_040279918   ⟹   XP_040135852
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244093491,956,266 - 1,962,302 (-)NCBI
RefSeq Acc Id: XM_040279919   ⟹   XP_040135853
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244093491,956,266 - 1,962,302 (-)NCBI
RefSeq Acc Id: XM_040279921   ⟹   XP_040135855
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244093491,956,266 - 1,962,302 (-)NCBI
RefSeq Acc Id: XM_040279922   ⟹   XP_040135856
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244093491,956,266 - 1,963,342 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_040135856   ⟸   XM_040279922
- UniProtKB: I3LX51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040135855   ⟸   XM_040279921
- UniProtKB: I3LX51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040135853   ⟸   XM_040279919
- UniProtKB: I3LX51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040135852   ⟸   XM_040279918
- UniProtKB: I3LX51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040135851   ⟸   XM_040279917
- UniProtKB: I3LX51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040135850   ⟸   XM_040279916
- UniProtKB: I3LX51 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000000609   ⟸   ENSSTOT00000000679
Protein Domains
SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000678 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000679.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1700 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
InterPro Hist-Lys_N-MTase_N UniProtKB/TrEMBL
  KMT5C_SET UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  Suv4-20/Set9 UniProtKB/TrEMBL
  Suv4-20_animal UniProtKB/TrEMBL
NCBI Gene Kmt5c ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE KMT5C UniProtKB/TrEMBL
  PTHR12977 UniProtKB/TrEMBL
Pfam SET UniProtKB/TrEMBL
PROSITE SAM_MT43_SUVAR420_2 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART SET UniProtKB/TrEMBL
Superfamily-SCOP SSF82199 UniProtKB/TrEMBL
UniProt I3LX51 ENTREZGENE, UniProtKB/TrEMBL