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Gene: Kat6a (lysine acetyltransferase 6A) Rattus norvegicus

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Symbol:

Kat6a

Name:

lysine acetyltransferase 6A

RGD ID:

1304892

Description:

Predicted to enable several functions, including histone acetyltransferase activity; transcription coactivator activity; and zinc ion binding activity. Involved in positive regulation of gene expression. Predicted to be located in cytosol and nuclear lumen. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in Arboleda-Tham syndrome and acute myeloid leukemia. Orthologous to human KAT6A (lysine acetyltransferase 6A); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

histone acetyltransferase KAT6A; histone acetyltransferase MYST3; K(lysine) acetyltransferase 6A; LOC306571; monocytic leukemia zinc finger homolog; monocytic leukemia zinc finger protein; Moz; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; MYST protein 3; MYST-3; Myst3; Runxbp2; Znf220

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KAT6A (lysine acetyltransferase 6A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Kat6a (K(lysine) acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kat6a (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KAT6A (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KAT6A (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kat6a (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KAT6A (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KAT6A (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kat6a (lysine acetyltransferase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZMAT5 (zinc finger matrin-type 5)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	KAT6A (lysine acetyltransferase 6A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Kat6a (K(lysine) acetyltransferase 6A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	kat6a (K(lysine) acetyltransferase 6A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	enok	Alliance	DIOPT (Hieranoid\|InParanoid\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SAS3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	75,787,411 - 75,868,584 (-)	NCBI		GRCr8
mRatBN7.2	16	69,084,914 - 69,165,923 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	69,084,914 - 69,163,606 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	74,358,565 - 74,437,271 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	77,790,634 - 77,869,724 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	73,039,779 - 73,118,865 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	73,942,669 - 74,020,750 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	73,943,455 - 74,023,005 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	73,575,194 - 73,655,378 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	73,553,868 - 73,634,794 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	73,556,791 - 73,632,511 (-)	NCBI
Celera	16	66,978,642 - 67,057,326 (-)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

RGD Manual Disease Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	acute myeloid leukemia		ISO	RGD:1312590	9590334	human gene in a mouse model;DNA:translocation:exon	RGD
Kat6a	Rat	Breast Neoplasms	severity	ISO	RGD:1312590	9590335	mRNA:increased expression:breast (human)	RGD
Kat6a	Rat	DiGeorge syndrome		ISO	RGD:1312591	9590333		RGD
Kat6a	Rat	Experimental Liver Neoplasms		IEP		2312274	protein:increased expression:liver (rat)	RGD

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	Arboleda-Tham syndrome		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome \| ClinVar Annotator: more ...	ClinVar	PMID:17374998\|PMID:23431171\|PMID:25728775\|PMID:25728777\|PMID:25741868\|PMID:26938784\|PMID:27133397\|PMID:28492532\|PMID:30245513\|PMID:31292255\|PMID:32041641\|PMID:33004838\|PMID:33318932\|PMID:34748993\|PMID:35892268\|PMID:35904121\|PMID:38177409
Kat6a	Rat	autism spectrum disorder		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Autism spectrum disorder	ClinVar	PMID:25741868\|PMID:28492532\|PMID:30504930
Kat6a	Rat	Craniosynostosis Syndrome, Autosomal Recessive		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Craniosynostosis syndrome	ClinVar	PMID:25741868\|PMID:30245513\|PMID:31292255
Kat6a	Rat	Developmental Disabilities		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Global developmental delay	ClinVar	PMID:25741868
Kat6a	Rat	genetic disease		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:17374998\|PMID:25728775\|PMID:25728777\|PMID:25741868\|PMID:27133397\|PMID:28135719\|PMID:28492532\|PMID:28518168\|PMID:30245513\|PMID:32041641\|PMID:32461654\|PMID:33004838\|PMID:35892268\|PMID:38177409
Kat6a	Rat	IMMUNODEFICIENCY 15		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Immunodeficiency 15	ClinVar	PMID:28492532
Kat6a	Rat	immunodeficiency 15B		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: IMMUNODEFICIENCY 15B	ClinVar	PMID:28492532
Kat6a	Rat	intellectual disability		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Intellectual disability \| ClinVar Annotator: match by term: intellectual disabilities	ClinVar	PMID:25741868\|PMID:28492532\|PMID:30245513\|PMID:34748993
Kat6a	Rat	Neurodevelopmental Disorders		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Neurodevelopmental abnormality \| ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868
Kat6a	Rat	syndromic intellectual disability		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Syndromic intellectual disability	ClinVar	PMID:25728777
Kat6a	Rat	torsion dystonia 6		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Torsion dystonia 6	ClinVar	PMID:28492532
Kat6a	Rat	Vein of Galen Aneurysm		ISO	RGD:1312590	8554872	ClinVar Annotator: match by term: Galen vein aneurysm	ClinVar	PMID:30578106

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	adenoid cystic carcinoma		ISO	RGD:1312590	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:23685749
Kat6a	Rat	medulloblastoma		ISO	RGD:1312590	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19270706
Kat6a	Rat	Prostatic Neoplasms		ISO	RGD:1312590	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:29662167

Imported Disease Annotations - MGI

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	DiGeorge syndrome		ISS	RGD:1312591	13592920	OMIM:188400	MouseDO

Imported Disease Annotations - OMIM

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	Arboleda-Tham syndrome		ISO	RGD:1312590	7240710		OMIM

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of KAT6A mRNA	CTD	PMID:20068009\|PMID:32145629
Kat6a	Rat	2,2',4,4'-Tetrabromodiphenyl ether	increases expression	EXP		6480464	2,2',4,4'-tetrabromodiphenyl ether results in increased expression of KAT6A mRNA	CTD	PMID:27291303
Kat6a	Rat	2,2',5,5'-tetrachlorobiphenyl	decreases expression	EXP		6480464	2,5,2',5'-tetrachlorobiphenyl results in decreased expression of KAT6A mRNA	CTD	PMID:23829299
Kat6a	Rat	2,3',4,4',5-Pentachlorobiphenyl	increases expression	ISO	RGD:1312591	6480464	2,3',4,4',5-pentachlorobiphenyl results in increased expression of KAT6A mRNA	CTD	PMID:31388691
Kat6a	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of KAT6A mRNA	CTD	PMID:32109520\|PMID:34747641
Kat6a	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of KAT6A mRNA	CTD	PMID:33387578
Kat6a	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2,6-dinitrotoluene affects the expression of KAT6A mRNA	CTD	PMID:21346803
Kat6a	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1312591	6480464	bisphenol S results in decreased expression of KAT6A mRNA	CTD	PMID:39298647
Kat6a	Rat	acrolein	multiple interactions	ISO	RGD:1312590	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ...	CTD	PMID:32699268
Kat6a	Rat	aflatoxin B1	increases methylation	ISO	RGD:1312590	6480464	Aflatoxin B1 results in increased methylation of KAT6A gene	CTD	PMID:27153756
Kat6a	Rat	alpha-pinene	multiple interactions	ISO	RGD:1312590	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ...	CTD	PMID:32699268
Kat6a	Rat	arsenite(3-)	multiple interactions	ISO	RGD:1312590	6480464	arsenite inhibits the reaction [G3BP1 protein binds to KAT6A mRNA]	CTD	PMID:32406909
Kat6a	Rat	benzene	increases expression	ISO	RGD:1312590	6480464	Benzene results in increased expression of KAT6A mRNA	CTD	PMID:19162166
Kat6a	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	RGD:1312590	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of KAT6A mRNA	CTD	PMID:19150397
Kat6a	Rat	benzo[a]pyrene diol epoxide I	increases expression	ISO	RGD:1312590	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of KAT6A mRNA	CTD	PMID:26238291
Kat6a	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1312591	6480464	Diethylhexyl Phthalate results in decreased expression of KAT6A mRNA	CTD	PMID:33754040
Kat6a	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of KAT6A mRNA	CTD	PMID:25181051
Kat6a	Rat	bisphenol A	increases expression	ISO	RGD:1312590	6480464	bisphenol A results in increased expression of KAT6A mRNA	CTD	PMID:36232920
Kat6a	Rat	bisphenol A	decreases methylation	ISO	RGD:1312590	6480464	bisphenol A results in decreased methylation of KAT6A gene	CTD	PMID:31601247
Kat6a	Rat	bisphenol A	multiple interactions	ISO	RGD:1312590	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of KAT6A gene	CTD	PMID:31601247
Kat6a	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of KAT6A mRNA	CTD	PMID:32145629
Kat6a	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of KAT6A mRNA	CTD	PMID:30816183\|PMID:32528016\|PMID:34947998\|PMID:36803626
Kat6a	Rat	bisphenol F	increases expression	ISO	RGD:1312591	6480464	bisphenol F results in increased expression of KAT6A mRNA	CTD	PMID:38685157
Kat6a	Rat	caffeine	increases phosphorylation	ISO	RGD:1312590	6480464	Caffeine results in increased phosphorylation of KAT6A protein	CTD	PMID:35688186
Kat6a	Rat	carbon nanotube	decreases expression	ISO	RGD:1312591	6480464	Nanotubes, Carbon results in decreased expression of KAT6A mRNA	CTD	PMID:25554681
Kat6a	Rat	chloroprene	increases expression	EXP		6480464	Chloroprene results in increased expression of KAT6A mRNA	CTD	PMID:23125180
Kat6a	Rat	chlorpyrifos	decreases expression	ISO	RGD:1312591	6480464	Chlorpyrifos results in decreased expression of KAT6A mRNA	CTD	PMID:37019170
Kat6a	Rat	cisplatin	increases phosphorylation	ISO	RGD:1312591	6480464	Cisplatin results in increased phosphorylation of KAT6A protein	CTD	PMID:22006019
Kat6a	Rat	cisplatin	decreases expression	ISO	RGD:1312590	6480464	Cisplatin results in decreased expression of KAT6A mRNA	CTD	PMID:27594783
Kat6a	Rat	copper(II) sulfate	increases expression	ISO	RGD:1312590	6480464	Copper Sulfate results in increased expression of KAT6A mRNA	CTD	PMID:19549813
Kat6a	Rat	coumarin	increases phosphorylation	ISO	RGD:1312590	6480464	coumarin results in increased phosphorylation of KAT6A protein	CTD	PMID:35688186
Kat6a	Rat	coumestrol	decreases expression	ISO	RGD:1312590	6480464	Coumestrol results in decreased expression of KAT6A mRNA	CTD	PMID:19167446
Kat6a	Rat	crocidolite asbestos	decreases expression	ISO	RGD:1312590	6480464	Asbestos, Crocidolite results in decreased expression of KAT6A mRNA	CTD	PMID:29523930
Kat6a	Rat	decabromodiphenyl ether	increases expression	EXP		6480464	decabromobiphenyl ether results in increased expression of KAT6A mRNA	CTD	PMID:23640034
Kat6a	Rat	decabromodiphenyl ether	decreases expression	EXP		6480464	decabromobiphenyl ether results in decreased expression of KAT6A mRNA	CTD	PMID:23640034
Kat6a	Rat	deguelin	increases expression	ISO	RGD:1312590	6480464	deguelin results in increased expression of KAT6A mRNA	CTD	PMID:33512557
Kat6a	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1312590	6480464	di-n-butylphosphoric acid affects the expression of KAT6A mRNA	CTD	PMID:37042841
Kat6a	Rat	dibutyl phthalate	decreases expression	EXP		6480464	Dibutyl Phthalate results in decreased expression of KAT6A mRNA	CTD	PMID:21266533
Kat6a	Rat	dicrotophos	increases expression	ISO	RGD:1312590	6480464	dicrotophos results in increased expression of KAT6A mRNA	CTD	PMID:28302478
Kat6a	Rat	diuron	decreases expression	EXP		6480464	Diuron results in decreased expression of KAT6A mRNA	CTD	PMID:25152437
Kat6a	Rat	dorsomorphin	multiple interactions	ISO	RGD:1312590	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kat6a	Rat	enzyme inhibitor	multiple interactions	ISO	RGD:1312590	6480464	[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ...	CTD	PMID:23301498
Kat6a	Rat	ethanol	increases expression	ISO	RGD:1312591	6480464	Ethanol results in increased expression of KAT6A mRNA	CTD	PMID:30319688
Kat6a	Rat	folpet	increases expression	ISO	RGD:1312591	6480464	folpet results in increased expression of KAT6A mRNA	CTD	PMID:31558096
Kat6a	Rat	formaldehyde	decreases expression	ISO	RGD:1312590	6480464	Formaldehyde results in decreased expression of KAT6A mRNA	CTD	PMID:20655997
Kat6a	Rat	FR900359	affects phosphorylation	ISO	RGD:1312590	6480464	FR900359 affects the phosphorylation of KAT6A protein	CTD	PMID:37730182
Kat6a	Rat	fulvestrant	multiple interactions	ISO	RGD:1312590	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of KAT6A gene	CTD	PMID:31601247
Kat6a	Rat	fulvestrant	decreases methylation	ISO	RGD:1312590	6480464	Fulvestrant results in decreased methylation of KAT6A gene	CTD	PMID:31601247
Kat6a	Rat	gallic acid	decreases expression	ISO	RGD:1312590	6480464	Gallic Acid results in decreased expression of KAT6A mRNA	CTD	PMID:34408198
Kat6a	Rat	geldanamycin	increases expression	ISO	RGD:1312590	6480464	geldanamycin results in increased expression of KAT6A mRNA	CTD	PMID:26705709
Kat6a	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of KAT6A mRNA	CTD	PMID:22061828
Kat6a	Rat	lead diacetate	increases expression	ISO	RGD:1312591	6480464	lead acetate results in increased expression of KAT6A mRNA	CTD	PMID:20542052
Kat6a	Rat	linsidomine	increases oxidation	EXP		6480464	linsidomine results in increased oxidation of KAT6A protein	CTD	PMID:28086193
Kat6a	Rat	mercury dibromide	decreases expression	ISO	RGD:1312590	6480464	mercuric bromide results in decreased expression of KAT6A mRNA	CTD	PMID:26272509
Kat6a	Rat	mercury dibromide	multiple interactions	ISO	RGD:1312590	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kat6a	Rat	mercury dichloride	decreases expression	ISO	RGD:1312590	6480464	Mercuric Chloride results in decreased expression of KAT6A mRNA	CTD	PMID:27188386
Kat6a	Rat	methamphetamine	increases expression	ISO	RGD:1312591	6480464	Methamphetamine results in increased expression of KAT6A mRNA	CTD	PMID:26307267
Kat6a	Rat	methapyrilene	decreases expression	EXP		6480464	Methapyrilene results in decreased expression of KAT6A mRNA	CTD	PMID:30467583
Kat6a	Rat	methidathion	decreases expression	ISO	RGD:1312591	6480464	methidathion results in decreased expression of KAT6A mRNA	CTD	PMID:34813904
Kat6a	Rat	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	decreases expression	ISO	RGD:1312590	6480464	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KAT6A mRNA	CTD	PMID:12756304
Kat6a	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of KAT6A mRNA	CTD	PMID:25729387
Kat6a	Rat	ozone	multiple interactions	ISO	RGD:1312590	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ...	CTD	PMID:32699268
Kat6a	Rat	p-chloromercuribenzoic acid	decreases expression	ISO	RGD:1312590	6480464	p-Chloromercuribenzoic Acid results in decreased expression of KAT6A mRNA	CTD	PMID:26272509
Kat6a	Rat	p-chloromercuribenzoic acid	multiple interactions	ISO	RGD:1312590	6480464	[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kat6a	Rat	panobinostat	multiple interactions	ISO	RGD:1312590	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ...	CTD	PMID:27188386
Kat6a	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	RGD:1312591	6480464	[perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of KAT6A mRNA	CTD	PMID:36331819
Kat6a	Rat	phenylmercury acetate	decreases expression	ISO	RGD:1312590	6480464	Phenylmercuric Acetate results in decreased expression of KAT6A mRNA	CTD	PMID:26272509
Kat6a	Rat	phenylmercury acetate	multiple interactions	ISO	RGD:1312590	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kat6a	Rat	SB 431542	multiple interactions	ISO	RGD:1312590	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Kat6a	Rat	sodium arsenite	increases expression	ISO	RGD:1312591	6480464	sodium arsenite results in increased expression of KAT6A mRNA	CTD	PMID:36209798
Kat6a	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of KAT6A mRNA	CTD	PMID:19281266
Kat6a	Rat	thimerosal	decreases expression	ISO	RGD:1312590	6480464	Thimerosal results in decreased expression of KAT6A mRNA	CTD	PMID:27188386
Kat6a	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of KAT6A mRNA	CTD	PMID:34492290
Kat6a	Rat	titanium dioxide	increases methylation	ISO	RGD:1312591	6480464	titanium dioxide results in increased methylation of KAT6A promoter	CTD	PMID:35295148
Kat6a	Rat	topotecan	decreases expression	EXP		6480464	Topotecan results in decreased expression of KAT6A mRNA	CTD	PMID:25729387
Kat6a	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of KAT6A mRNA	CTD	PMID:25729387
Kat6a	Rat	trichostatin A	decreases expression	ISO	RGD:1312590	6480464	trichostatin A results in decreased expression of KAT6A mRNA	CTD	PMID:24935251
Kat6a	Rat	troglitazone	decreases expression	ISO	RGD:1312591	6480464	troglitazone results in decreased expression of KAT6A mRNA	CTD	PMID:28973697
Kat6a	Rat	tungsten	decreases expression	ISO	RGD:1312591	6480464	Tungsten results in decreased expression of KAT6A mRNA	CTD	PMID:30912803
Kat6a	Rat	valproic acid	decreases methylation	ISO	RGD:1312590	6480464	Valproic Acid results in decreased methylation of KAT6A gene	CTD	PMID:29154799
Kat6a	Rat	valproic acid	decreases expression	ISO	RGD:1312590	6480464	Valproic Acid results in decreased expression of KAT6A mRNA	CTD	PMID:23179753\|PMID:24935251\|PMID:28001369
Kat6a	Rat	valproic acid	affects splicing	EXP		6480464	Valproic Acid affects the splicing of KAT6A mRNA	CTD	PMID:29427782

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	aorta morphogenesis	acts_upstream_of_or_within	ISO	RGD:1312591	1624291	MGI:4418468\|MGI:98493 PMID:22921202	RGD	PMID:22921202
Kat6a	Rat	cellular senescence	involved_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	cellular senescence	involved_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	cellular senescence	involved_in	ISO	RGD:1312590	1624291	PMID:23431171	RGD	PMID:23431171
Kat6a	Rat	chromatin organization	involved_in	IEA	UniProtKB-KW:KW-0156	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kat6a	Rat	embryonic hemopoiesis	acts_upstream_of_or_within	ISO	RGD:1312591	1624291	PMID:16702405	RGD	PMID:16702405
Kat6a	Rat	face morphogenesis	acts_upstream_of_or_within	ISO	RGD:1312591	1624291	MGI:4418468\|MGI:98493 PMID:22921202	RGD	PMID:22921202
Kat6a	Rat	heart morphogenesis	acts_upstream_of_or_within	ISO	RGD:1312591	1624291	MGI:4418468\|MGI:98493 PMID:22921202	RGD	PMID:22921202
Kat6a	Rat	myeloid cell differentiation	involved_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	myeloid cell differentiation	involved_in	ISO	RGD:1312590	1624291	PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	myeloid cell differentiation	involved_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	negative regulation of DNA-binding transcription factor activity	acts_upstream_of_or_within	ISO	RGD:1312591	1624291	MGI:4418468 PMID:22921202	RGD	PMID:22921202
Kat6a	Rat	negative regulation of DNA-templated transcription	involved_in	IEA	UniRule:UR001806739	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Kat6a	Rat	negative regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	negative regulation of DNA-templated transcription	involved_in	ISO	RGD:1312590	1624291	PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	negative regulation of DNA-templated transcription	involved_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	nucleosome assembly	involved_in	IEA	InterPro:IPR005818	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kat6a	Rat	positive regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	positive regulation of DNA-templated transcription	involved_in	ISO	RGD:1312590	1624291	PMID:11742995, PMID:11965546, PMID:18794358	RGD	PMID:11742995\|PMID:11965546\|PMID:18794358
Kat6a	Rat	positive regulation of DNA-templated transcription	involved_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	positive regulation of gene expression		IDA		2312274	Gstp1	RGD
Kat6a	Rat	protein acetylation	involved_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	protein acetylation	involved_in	ISO	RGD:1312590	1624291	PMID:23431171	RGD	PMID:23431171
Kat6a	Rat	regulation of DNA-templated transcription	involved_in	ISO	RGD:1312590	1624291	PMID:18794358	RGD	PMID:18794358
Kat6a	Rat	regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR002717	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kat6a	Rat	regulation of transcription by RNA polymerase II	involved_in	IBA	CGD:CAL0000179231\|FB:FBgn0028387\|FB:FBgn0034975\|MGI:2182799\|PANTHER:PTN004172926\|RGD:1566399\|SGD:S000005770	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	somatic stem cell population maintenance	acts_upstream_of_or_within	ISO	RGD:1312591	1624291	MGI:3626344 PMID:16651658, PMID:16702405	RGD	PMID:16651658\|PMID:16702405

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	chromatin	is_active_in	IBA	CGD:CAL0000179231\|FB:FBgn0034975\|MGI:1919307\|MGI:2182799\|PANTHER:PTN004172926\|PomBase:SPAC637.12c\|SGD:S000000148\|SGD:S000005770\|TAIR:locus:2144776\|TAIR:locus:2174764\|UniProtKB:O95251\|UniProtKB:Q8WYB5\|UniProtKB:Q92794\|ZFIN:ZDB-GENE-021022-3	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	cytosol	located_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	cytosol	located_in	ISO	RGD:1312590	1624291		RGD	GO_REF:0000052
Kat6a	Rat	MOZ/MORF histone acetyltransferase complex	part_of	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	MOZ/MORF histone acetyltransferase complex	part_of	IBA	FB:FBgn0034975\|PANTHER:PTN000065047\|UniProtKB:Q8WYB5\|UniProtKB:Q92794	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	MOZ/MORF histone acetyltransferase complex	part_of	ISO	RGD:1312590	1624291	PMID:16387653, PMID:18794358	RGD	PMID:16387653\|PMID:18794358
Kat6a	Rat	MOZ/MORF histone acetyltransferase complex	part_of	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	nuclear speck	located_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	nuclear speck	located_in	ISO	RGD:1312590	1624291		RGD	GO_REF:0000052
Kat6a	Rat	nucleolus	located_in	ISO	RGD:1312590	1624291		RGD	GO_REF:0000052
Kat6a	Rat	nucleolus	located_in	IEA	UniProtKB-SubCell:SL-0188	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kat6a	Rat	nucleolus	located_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	nucleoplasm	located_in	IEA	UniProtKB-SubCell:SL-0190	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kat6a	Rat	nucleosome	part_of	IEA	InterPro:IPR005818	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kat6a	Rat	nucleus	located_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kat6a	Rat	nucleus	is_active_in	IBA	FB:FBgn0028387\|MGI:1919307\|MGI:2182799\|MGI:2442415\|PANTHER:PTN004172926\|PomBase:SPAC637.12c\|TAIR:locus:2144776\|TAIR:locus:2144841\|TAIR:locus:2169779\|TAIR:locus:2174764\|UniProtKB:D6XIY7\|UniProtKB:O95251\|UniProtKB:Q6ZJM9\|UniProtKB:Q8III2\|UniProtKB:Q8WUB8\|UniProtKB:Q8WYB5\|UniProtKB:Q92794	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kat6a	Rat	nucleus	located_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	nucleus	located_in	IEA	UniRule:UR001806739	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Kat6a	Rat	nucleus	located_in	ISO	RGD:1312591	1624291	PMID:10716735	RGD	PMID:10716735
Kat6a	Rat	nucleus	located_in	ISO	RGD:1312590	1624291	PMID:11742995, PMID:18794358	RGD	PMID:11742995\|PMID:18794358
Kat6a	Rat	PML body	located_in	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	PML body	located_in	IEA	UniProtKB-SubCell:SL-0465	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kat6a	Rat	PML body	located_in	ISO	RGD:1312590	1624291	PMID:23431171	RGD	PMID:23431171
Kat6a	Rat	PML body	located_in	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	acyltransferase activity	enables	IEA	UniProtKB-KW:KW-0012	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kat6a	Rat	chromatin binding	enables	IBA	MGI:2442415\|PANTHER:PTN004172926	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	chromatin binding	enables	ISO	RGD:1312591	1624291	MGI:1922816 PMID:22921202	RGD	PMID:22921202
Kat6a	Rat	DNA binding	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	DNA binding	enables	IEA	InterPro:IPR005818\|InterPro:IPR048589	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kat6a	Rat	DNA binding	enables	ISO	RGD:1312590	1624291	PMID:17925393	RGD	PMID:17925393
Kat6a	Rat	DNA binding	enables	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	DNA-binding transcription factor binding	enables	ISO	RGD:1312590	1624291	UniProtKB:Q01196-1 PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	DNA-binding transcription factor binding	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	histone acetyltransferase activity	enables	ISO	RGD:1312590	1624291	PMID:17925393	RGD	PMID:17925393
Kat6a	Rat	histone acetyltransferase activity	enables	IEA	InterPro:IPR002717	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kat6a	Rat	histone acetyltransferase activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	histone acetyltransferase activity	enables	IEA	EC:2.3.1.48	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Kat6a	Rat	histone H3 acetyltransferase activity	enables	IBA	FB:FBgn0034975\|MGI:2442415\|PANTHER:PTN000834868\|UniProtKB:Q8WYB5\|UniProtKB:Q92794	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	histone H3K14 acetyltransferase activity	enables	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	histone H3K14 acetyltransferase activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	histone H3K14 acetyltransferase activity	enables	ISO	RGD:1312590	1624291	PMID:11742995, PMID:16387653	RGD	PMID:11742995\|PMID:16387653
Kat6a	Rat	histone H3K9 acetyltransferase activity	enables	ISO	RGD:1312591	1624291	MGI:4418468 PMID:22921202	RGD	PMID:22921202
Kat6a	Rat	histone H4K12 acetyltransferase activity	enables	ISO	RGD:1312590	1624291	PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	histone H4K12 acetyltransferase activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	histone H4K16 acetyltransferase activity	enables	ISO	RGD:1312590	1624291	PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	histone H4K16 acetyltransferase activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	histone H4K5 acetyltransferase activity	enables	ISO	RGD:1312590	1624291	PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	histone H4K5 acetyltransferase activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	histone H4K5 acetyltransferase activity	enables	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	histone H4K8 acetyltransferase activity	enables	ISO	RGD:1312590	1624291	PMID:11742995	RGD	PMID:11742995
Kat6a	Rat	histone H4K8 acetyltransferase activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kat6a	Rat	protein binding	enables	ISO	RGD:1312590	1624291	UniProtKB:P04637\|UniProtKB:P29590-4\|UniProtKB:P61964\|UniProtKB:Q03164-PRO_0000390950\|UniProtKB:Q13950 PMID:11965546, PMID:20581860, PMID:23431171	RGD	PMID:11965546\|PMID:20581860\|PMID:23431171
Kat6a	Rat	protein binding		IPI	RGD:628633	2312274		RGD
Kat6a	Rat	protein binding	enables	ISO	RGD:1312591	1624291	PR:P17433 PMID:16702405	RGD	PMID:16702405
Kat6a	Rat	protein-lysine-acetyltransferase activity	enables	IEA	RHEA:45948	1600115	GO_REF:0000116	RHEA	GO_REF:0000116
Kat6a	Rat	transcription coactivator activity	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	transcription coactivator activity	enables	ISO	RGD:1312590	1624291	PMID:11742995, PMID:11965546	RGD	PMID:11742995\|PMID:11965546
Kat6a	Rat	transcription coregulator activity	enables	IBA	FB:FBgn0028387\|PANTHER:PTN004172926\|SGD:S000005770\|UniProtKB:Q8WYB5\|UniProtKB:Q92794	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kat6a	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kat6a	Rat	zinc ion binding	enables	ISS	UniProtKB:Q92794	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kat6a	Rat	zinc ion binding	enables	ISO	RGD:1312590	1624291	PMID:17925393	RGD	PMID:17925393
Kat6a	Rat	zinc ion binding	enables	IEA	UniProtKB:Q92794\|ensembl:ENSP00000265713	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kat6a	Rat	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Pathway Annotations Click to see Annotation Detail View

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kat6a	Rat	histone modification pathway		ISO	RGD:1312590	9104959		RGD

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

adenoid cystic carcinoma (ISO)

Arboleda-Tham syndrome (ISO)

autism spectrum disorder (ISO)

Breast Neoplasms (ISO)

Craniosynostosis Syndrome, Autosomal Recessive (ISO)

Developmental Disabilities (ISO)

DiGeorge syndrome (ISO,ISS)

Experimental Liver Neoplasms (IEP)

genetic disease (ISO)

IMMUNODEFICIENCY 15 (ISO)

immunodeficiency 15B (ISO)

intellectual disability (ISO)

medulloblastoma (ISO)

Neurodevelopmental Disorders (ISO)

Prostatic Neoplasms (ISO)

syndromic intellectual disability (ISO)

torsion dystonia 6 (ISO)

Vein of Galen Aneurysm (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

arsenite(3-) (ISO)

benzene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chloroprene (EXP)

chlorpyrifos (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

decabromodiphenyl ether (EXP)

deguelin (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

diuron (EXP)

dorsomorphin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

folpet (ISO)

formaldehyde (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gallic acid (ISO)

geldanamycin (ISO)

gentamycin (EXP)

lead diacetate (ISO)

linsidomine (EXP)

mercury dibromide (ISO)

mercury dichloride (ISO)

methamphetamine (ISO)

methapyrilene (EXP)

methidathion (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

oxaliplatin (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

troglitazone (ISO)

tungsten (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aorta morphogenesis (ISO)

cellular senescence (IEA,ISO,ISS)

chromatin organization (IEA)

embryonic hemopoiesis (ISO)

face morphogenesis (ISO)

heart morphogenesis (ISO)

myeloid cell differentiation (IEA,ISO,ISS)

negative regulation of DNA-binding transcription factor activity (ISO)

negative regulation of DNA-templated transcription (IEA,ISO,ISS)

nucleosome assembly (IEA)

positive regulation of DNA-templated transcription (IEA,ISO,ISS)

positive regulation of gene expression (IDA)

protein acetylation (ISO,ISS)

regulation of DNA-templated transcription (IEA,ISO)

regulation of transcription by RNA polymerase II (IBA)

somatic stem cell population maintenance (ISO)

Cellular Component

chromatin (IBA)

cytosol (IEA,ISO)

MOZ/MORF histone acetyltransferase complex (IBA,IEA,ISO,ISS)

nuclear speck (IEA,ISO)

nucleolus (IEA,ISO)

nucleoplasm (IEA)

nucleosome (IEA)

nucleus (IBA,IEA,ISO,ISS)

PML body (IEA,ISO,ISS)

Molecular Function

acyltransferase activity (IEA)

chromatin binding (IBA,ISO)

DNA binding (IEA,ISO,ISS)

DNA-binding transcription factor binding (IEA,ISO)

histone acetyltransferase activity (IEA,ISO)

histone H3 acetyltransferase activity (IBA)

histone H3K14 acetyltransferase activity (IEA,ISO,ISS)

histone H3K9 acetyltransferase activity (ISO)

histone H4K12 acetyltransferase activity (IEA,ISO)

histone H4K16 acetyltransferase activity (IEA,ISO)

histone H4K5 acetyltransferase activity (IEA,ISO,ISS)

histone H4K8 acetyltransferase activity (IEA,ISO)

metal ion binding (IEA)

protein binding (IPI,ISO)

protein-lysine-acetyltransferase activity (IEA)

transcription coactivator activity (IEA,ISO)

transcription coregulator activity (IBA)

transferase activity (IEA)

zinc ion binding (IEA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13).	Chinen Y, etal., Genes Chromosomes Cancer. 2014 Apr;53(4):299-308. doi: 10.1002/gcc.22140. Epub 2014 Jan 21.
2.	MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.	Deguchi K, etal., Cancer Cell. 2003 Mar;3(3):259-71.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Histone acetyltransferase MOZ acts as a co-activator of Nrf2-MafK and induces tumour marker gene expression during hepatocarcinogenesis.	Ohta K, etal., Biochem J. 2007 Mar 15;402(3):559-66.
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	Physical and functional HAT/HDAC interplay regulates protein acetylation balance.	Peserico A and Simone C, J Biomed Biotechnol. 2011;2011:371832. doi: 10.1155/2011/371832. Epub 2010 Dec 5.
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.	Turner-Ivey B, etal., Neoplasia. 2014 Aug;16(8):644-55. doi: 10.1016/j.neo.2014.07.007.
13.	MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.	Voss AK, etal., Dev Cell. 2012 Sep 11;23(3):652-63. doi: 10.1016/j.devcel.2012.07.010. Epub 2012 Aug 23.

Additional References at PubMed

PMID:10716735	PMID:11742995	PMID:11965546	PMID:15057822	PMID:16387653	PMID:16651658	PMID:16702405	PMID:17925393	PMID:18794358	PMID:23431171

Genomics

Comparative Map Data

Kat6a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	75,787,411 - 75,868,584 (-)	NCBI		GRCr8
mRatBN7.2	16	69,084,914 - 69,165,923 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	69,084,914 - 69,163,606 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	74,358,565 - 74,437,271 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	77,790,634 - 77,869,724 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	73,039,779 - 73,118,865 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	73,942,669 - 74,020,750 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	73,943,455 - 74,023,005 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	73,575,194 - 73,655,378 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	73,553,868 - 73,634,794 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	73,556,791 - 73,632,511 (-)	NCBI
Celera	16	66,978,642 - 67,057,326 (-)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

KAT6A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	41,929,479 - 42,051,987 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	41,929,479 - 42,051,994 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	41,786,997 - 41,909,505 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	41,906,154 - 42,028,662 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	41,907,425 - 42,028,635	NCBI
Celera	8	40,736,067 - 40,858,643 (-)	NCBI		Celera
Cytogenetic Map	8	p11.21	NCBI
HuRef	8	40,314,984 - 40,434,974 (-)	NCBI		HuRef
CHM1_1	8	41,835,431 - 41,957,801 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	42,203,787 - 42,326,296 (-)	NCBI		T2T-CHM13v2.0

Kat6a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	23,349,458 - 23,433,275 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	23,349,551 - 23,433,275 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	22,859,442 - 22,943,259 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	22,859,535 - 22,943,259 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	23,970,011 - 24,053,734 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	24,325,080 - 24,408,807 (+)	NCBI		MGSCv36	mm8
Celera	8	24,351,439 - 24,433,561 (+)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	11.42	NCBI

Kat6a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955536	900,198 - 1,015,520 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955536	900,198 - 1,015,520 (+)	NCBI	ChiLan1.0	ChiLan1.0

KAT6A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	60,382,028 - 60,506,436 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	36,099,345 - 36,222,083 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	41,173,833 - 41,296,547 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	38,622,419 - 38,742,273 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	38,625,156 - 38,741,538 (-)	Ensembl	panpan1.1		panPan2

KAT6A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	23,604,629 - 23,717,047 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	23,604,200 - 23,724,252 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	24,108,113 - 24,221,865 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	25,351,804 - 25,466,743 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	25,351,846 - 25,464,076 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	23,722,919 - 23,836,884 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	24,284,506 - 24,398,604 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	24,335,164 - 24,449,218 (+)	NCBI		UU_Cfam_GSD_1.0

Kat6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	46,646,353 - 46,748,108 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936785	603,478 - 701,791 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936785	602,754 - 704,504 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KAT6A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	17	11,002,818 - 11,109,974 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	12,485,672 - 12,536,507 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KAT6A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	39,912,120 - 40,035,776 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	39,911,776 - 39,962,735 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	1,751,940 - 1,875,909 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kat6a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	1,240,292 - 1,376,072 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624780	1,237,326 - 1,378,718 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Kat6a
392 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	13
Count of miRNA genes:	11
Interacting mature miRNAs:	12
Transcripts:	ENSRNOT00000037389
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat
1298527	Arunc2	Aerobic running capacity QTL 2	2.9		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	68532716	75029966	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	24325513	69325513	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat

Markers in Region

RH140730

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	69,086,371 - 69,086,598 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	73,944,127 - 73,944,353	NCBI	Rnor6.0
Rnor_5.0	16	73,576,652 - 73,576,878	UniSTS	Rnor5.0
RGSC_v3.4	16	73,555,326 - 73,555,552	UniSTS	RGSC3.4
Celera	16	66,980,100 - 66,980,326	UniSTS
RH 3.4 Map	16	662.91	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

Myst3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	69,163,043 - 69,163,292 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	74,020,188 - 74,020,436	NCBI	Rnor6.0
Rnor_5.0	16	73,652,713 - 73,652,961	UniSTS	Rnor5.0
RGSC_v3.4	16	73,631,997 - 73,632,245	UniSTS	RGSC3.4
Celera	16	67,056,764 - 67,057,012	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

Myst3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	69,086,168 - 69,086,324 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	73,943,924 - 73,944,079	NCBI	Rnor6.0
Rnor_5.0	16	73,576,449 - 73,576,604	UniSTS	Rnor5.0
RGSC_v3.4	16	73,555,123 - 73,555,278	UniSTS	RGSC3.4
Celera	16	66,979,897 - 66,980,052	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094587	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB195309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000037389 ⟹ ENSRNOP00000037279

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	69,086,831 - 69,163,606 (-)	Ensembl
Rnor_6.0 Ensembl	16	73,945,331 - 74,020,437 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078743 ⟹ ENSRNOP00000071789

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	69,084,914 - 69,163,606 (-)	Ensembl
Rnor_6.0 Ensembl	16	73,943,455 - 74,023,005 (-)	Ensembl

RefSeq Acc Id:

NM_001100570 ⟹ NP_001094040

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	75,787,411 - 75,866,099 (-)	NCBI
mRatBN7.2	16	69,084,914 - 69,163,606 (-)	NCBI
Rnor_6.0	16	73,942,669 - 74,020,750 (-)	NCBI
Rnor_5.0	16	73,575,194 - 73,655,378 (-)	NCBI
RGSC_v3.4	16	73,553,868 - 73,634,794 (-)	RGD
Celera	16	66,978,642 - 67,057,326 (-)	NCBI

Sequence:

show sequence

GCTTAAGATACTCATTTTCTGCTTGAAGCTGGGAATGAGATGTATGGAACCCAAGAGTGTGTGT
GGAGTAGACACCAAGGTGTGGTGCTAGTGAGGCATTTGAAGATACATCAGAAAAAGCAGCCGTT
TGGTTTCTGAGGTAAAAGTAGGTTGTAATTCTGTTTTGTGAACGGAGGGAAGACTCAGGCCAGA
AATCTTGTATGCTATGGTTAACTGGTTCCCACCCTCCGCGAGTCATGTTTTCCATGGTGTAAGA
CTTACTCAGCATCAGGATAAGGGATAGCGACTCTATGGATAGACAGAATCCTTCACCATGGTAA
AGCTCGCTAACCCGCTGTACACGCAGTGGATTTTGGAGGCCATCAAAAAAGTCAAGAAGCAGAA
ACAGCGACCTTCAGAAGAAAGAATATGCAATGCAGTGTCGTCCTCCCACGGCTTAGATCGGAAA
ACTGTCCTGGAGCAGTTGGAGCTGAGTGTTAAAGATGGCACGATCCTAAAAGTCTCAAACAAAG
GTCTCAACTCCTATAAAGATCCTGATAATCCTGGGCGAATAGCACTTCCTAAACCTCGAAACCA
TGGAAAGTTGGATAATAAACAAAGTGTGGATTGGAATAAATTACTCAAGCGGGCATTTGAGGGC
TTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGTATTGAACGCTTTTTGAAAAGCCAGAAGGATG
TGTCTGCTGCCTGTGGAGGCACTGCTGCCTCTGGGTTTCACCAGCAGCTGCGGTTGGCGATCAA
GCGTGCCGTTGGTCATGGCCGACTCCTTAAAGATGGACCTCTCTACCGGCTCAACACCAAGGCA
GCCAATGCTGAAGGGAAAGAGGGCTGCGAGTCGCTCTCGTGTTTACCTCCTGTGTCACTGCTTC
CACACGAGAAAGATAAGCCGGTTGCTGAACCAATCCCCATCTGTAGTTTCTGTCTTGGTACAAA
AGAACAAAACCGGGAAAAGAAGCCTGAGGACCTCATCTCCTGCGCAGACTGTGGCAATAGCGGT
CACCCATCCTGCTTAAAGTTCTCCCCAGAACTCACAGTGAGAGTGAGGGCCCTGCGGTGGCAGT
GCATCGAGTGCAAAACGTGCAGCTCCTGTCGCGATCAAGGCAAAAACGCAGATAACATGCTCTT
TTGTGATTCATGTGACCGAGGTTTTCACATGGAGTGTTGTGACCCACCCCTCACACGGATGCCA
AAAGGCATGTGGATATGTCAGATATGCCGACCCAGGAAAAAAGGACGGAAACTGCTACAAAAGA
AGGCAGCACAGATAAAACGGCGCTATGCTAATCCAATAGGACGTCCAAAAAACAGGTTAAAGAA
ACAAAGCACGGTATCAAAAGGTCCCTTTAGCAAAGTTCGAACTGGTCCTGGAAGGGGTCGGAAA
CGTAAAATCACTGTATCCAGCCAGTCTGCGTCATCCTCAGAAGAAGGCTATTTAGAGCGGATAG
ATGGCTTGGACTTCTGCAGAGATAGCAGTGCCCCCTTGAAGTTCAACAAGAAAACCAAAGGGCT
CATTGATGGCCTTACCAAATTCTTCACCCCTTCTCCTGATGGGCGGAAAGCCCGAGGGGAGGCG
GTAGACTACTCTGAGCTCAGAATCAGGAAAAAGGGCAACAGAAAATCAAGTACTTCACATTGGC
CCACAGACAATCAGGACGGCTGGGAAAGCAAACAGGAAAGTGAGGAGCGGCTTTTTGGGAGCCA
AGAAATCATGACGGAAAGAGATATGGAATTATTTCGTGATATCCAAGAACAAGCACTGCAGAAA
GTTGGAGTAACTGGGCCCCCTGATCCACAAGTCCGCTGTCCCTCCGTCATTGAGTTTGGGAAGT
ATGAAATCCACACCTGGTATTCCTCTCCATATCCTCAAGAATACTCAAGGCTGCCTAAATTGTA
TCTTTGTGAGTTCTGTCTAAAATATATGAAAAGTAGAACTATTCTCCAGCAGCACATGAAGAAA
TGTGGTTGGTTCCATCCTCCCGCCAATGAGATTTACCGAAAGAATAATATTTCTGTCTTTGAGG
TTGATGGGAATGTGAGTACCATTTATTGTCAAAATCTGTGTCTCTTGGCAAAGTTGTTTCTTGA
CCACAAAACACTCTATTATGACGTGGAGCCATTTCTCTTCTATGTTTTAACACAGAATGATGTC
AAGGGCTGCCACCTTGTTGGCTACTTTTCTAAAGAAAAGCACTGCCAACAGAAATACAATGTCT
CCTGTATAATGATTCTTCCCCAATACCAACGTAAGGGCTACGGCAGGTTTCTCATCGATTTCAG
TTATTTGTTATCAAAGCGTGAAGGCCAAGCAGGCTCTCCTGAGAAACCACTATCAGATCTAGGT
CGTCTTTCCTACATGGCTTATTGGAAAAGTGTAATCTTGGAGTGCCTTTATCACCAGAATGACA
AACAGATCAGCATTAAGAAGCTGAGTAAGCTGACTGGAGTCTGCCCGCAAGACATTACTTCCAC
ACTCCACCACCTACGGATGCTGGACTTCCGAAGTGACCAATTTGTGATTATCCGCCGGGAAAAA
CTTATCCAGGATCACATGGCGAAGCTCCAGCTGAATCTTCGACCTGTCGATGTAGATCCAGAAT
GCTTACGCTGGACTCCAGTCATAGTCTCCAACTCTGTCGTCTCAGAGGAGGAGGATGAGGAGGC
TGATGACGGAGAGAAAGAAGAGCCCCAAGGCCAAGAAAGAGAGTTAGAGACCAGGGAAAGGGTG
GGAAAGTCTGTGTCTCGGGAGAACAAAGATCAGGATTCTTCCTCTTTAATAGAAAGTGAAAAGA
AACCAGAAGTCAAGGAACTAGCCAGCTCTTCACGTCTGAGCAAACAGGCCCTTGTCCGGGACAG
TCTTCCTGCAAATAGCCAGCCACCTCGGAGGGGCCGCTGTGGGAGGAAGAACAGAAAGACACAG
GAACGTTTTGGTGATAAAGATTCTAAGATGCTTGTGGGTGAGACGTTATCCACTTCTCAGGAGC
AATATGGAGAATGCGAGGAGAAGTCAGCAGCCTCCCGAGAGCGTTACACTGAGGTGGGAGAGCA
GCCAGCAGCCCCTCAGGCACAAGCAGACGGGAACCCAGACATCCCCAAGGGCAGGTTCAGTGAG
AGCGCGGATTTGTGGCGAGGACAGCTGAAGAAAAGCCCTGAGACCCTGAAGTGCCGATTGCCAG
AAGGGAATGACAGACTTCCGTGCTGCTACACCGATGGTGACAGGGCTGTCTTTAGGGGCTTCAG
CGAAAGTAGTGAGGAAGAGGAGGAGCCAGAAAGTCCTCGGTCAAACTCGCCACCAGTGCTCACA
AAGCCCACGCTGAAAAGAAAGAAACCAATTCTTCACCGAAGAAGGAGAGTCCGCAAGCGGAAAC
ACCACAATAGCAGTGTCGTCACAGAAACGATCTCTGAGACCACTGAGGTGTTAGATGAGCCTTT
TGAAGACTCTGACTCTGAGAGACCAATGCCAAGACTGGAACCTACATTCGAGATTGAGGAGGAG
GAGGAGGAGGAGGATGAAAATGAGCTCTTCCCCAGAGGGTACTTTCATTGCTTGTCCTCACAGG
ACATCCTTAGGTGTCAGGCTTCCTCCAAGAGGACGGCGTCTAAAGATGAGGAGGAAGAAGAGGA
GGAGTCAGACGATGCAGATGACACTCCTGTCCTAAAGCCAGTATCTCTCTTGAGAAAATGTGAT
GTGAACAGTGCTTCACTTGAGCCAGATACCTCTACACCTATGAAAAAGAAAAAGGGATGGCCCA
AAGGCAAGAGCCGAAAACCTATCCACTGGAAGAAAAGGCCTGGGCGGAAACCAGGATTTAAATT
GAATCAGGACATCATAGCTGTTTCTACACAGGAATGCATAGTTGAGCCCATAGTCCCCATTAAA
CCAGGACGTAAACCCAGAACTCAAGAGAGTGAAGAACTTGTTGAGGTGAAGGAGGGCCTGGTGG
AAGAAAGGAAGGAGGAAATGCATACAGAAGCAGACGAAGAGGCCGAGGAGGAAGAGGATGCAGC
CAGCAGTGACATTAGAGCCATGTCCCCATTGGACAGCAGCAATAGCCCTGATGCAGACCCGAAA
GAACCTGAGGCAGAAGAGGAAGAGGAGAAGCCGTTGGACGATCCGAGGCAATCAGAGGAAGAGC
CTCAAGAGCTGGAAGAACAGGAGCAAGAGGAAGAGGACGAGGTGACTGCAGAGGCAAACCAGAA
TGAAGACCATGATGCTGACGATGAGGACGACGGCCACCTGGATTCACTGAAGACAAAAGAGCCA
GAGGGGCAGCCGGCTAGAGAAGACGGCACAGAGGAGCCCGGCACCCAGGAGTCTTTTTTAGATG
CAAGCATACAGGACAGCAGGGAGAACGCGAAGGATAAAGATGAAACTGAAGCGGATTCTGAAGA
GGAACAGCCTTCCCATGAGGCTTCTGTGGGATCAGAGACCATGCCAGGCTCTGAGGAGGACCAT
GAGGAGGACTCAAACACTAAGGAAGAATTAATTGAGCTAAAAGAGGAGGAAGAGATCCCACACA
GTGAACTGGATCTGGAAACTGTACAGGCAGTGCAGTCTTTGACTCAAGAAGAAAGCAGTGAGCA
TGAAGGAGCCTACCAGGACTGTGAGGAAACTCTTGCGGCTTGCCAGACTCTACAGAGTTACACC
CACACTGACGAGGACCCTCAGATGTCAATGGTTGAAGACTGCCATGCCTCAGAGCATAATAGCC
CAATATCCTCCATTCCGTCTCATCCTAGCCAGTCAGTCCGCTCCGTCAGCAGCCCCAGCATGCC
TGCCCTGGAGAGTGGCTACACACAGATCAGCCCAGAGCAAGGATCCCTGTCCGCACCCTCTATG
CAGAACATGGAGACCAGCCCCATGATGGATGTGCCTTCCGTATCAGACCACTCTCAGCAGGTGG
TAGACAGTGGCTTCAGTGACCTGGGCAGCATCGAGAGCACCACAGAGAACTATGAGAACCCAAG
CAGCTATGACTCTACCATGGGCAGCAGTATTTGTGGGAATAACTCCTCTCAGAGCAGCTGCTCC
TACGGTGGCCTGTCATCTTCAAGCAGCCTCACCCAGAACAGTTGTGTTGTCACTCAGCAAATGG
CAAGCATGGGCAACAGCTGTAGCATGCTGCAGCAAAACAGCGTCCAACCAGCTACCAACTGCAA
CATCAAGTCGCCTCAGACCTGTGTGGTGGAAAGGCCTCCCAGTAACCAGCAGCCGCCGCCACCA
CCACCACCCCCGCCGCCACCACAGCAGCCGCAGCCGCAGCCGCAGCAGCAGGCAGCCCCACAGC
CTCCCCCACCACAGCCGCAGCAGCAGCCGCCCCCTCCACCGCAGCAGCAGCCCCAGCCCCCACC
TCCACCCCAGCAGCAGCCCCCTCTGTCGCAGTGTAGCATGAACAACAGCTTCACTGCCGCGCCA
ATGATAATGGAGATACCAGAGTCCGGGGGTACTGGGAACATCAGCATCTACGAGAGGATTCCAG
GGGATTTTGGCGCTGGCAGCTACTCTCAACCGTCAGCCACCTTCAGTCTCGCCAAGTTGCAGCA
GCTGACTAACACCATTATGGACCCTCATGCCATGCCTTACAGTCATTCTCCGGCCGTGACTTCC
TATGCAACCAGTGTTTCTCTGTCTAATACGGGACTGGCTCAGCTAGCTCCATCTCATCCCTTAG
CCGGGACCCCTCAAGCACAAGCCACCATGACGCCACCCCCAAACTTGGCACCTACTACTATGAA
CCTCACGTCACCTCTGCTGCAGTGCAACATGTCTGCCACCAACATTGGGATCCCTCACACGCAG
AGGTTGCAGGGGCAGATGCCAGTCAAGGGGCACATTTCTATCCGTTCCAAGTCTGCACCTTTAC
CCTCTGCAACTGCACACCAACAGCAGCTCTATGGCCGCAGCCCCCCAGCAGTTGCCATGCAGGC
TGGCCCTCGTGCACTGGCCGTTCAGCGTGGCATGAACATGGGGGTTAACTTAATGCCCACTCCA
GCCTATAATGTCAATTCCATGAATATGAACACCTTGAATGCCATGAACAGCTATCGAATGACAC
AGCCCATGATGAACAGCAGTTACCATAGTAACCCTGCCTACATGAACCAGACAGCACAGTATCC
TATGCAGATGCAGATGGGAATGATGGGGAGCCAGGCCTATACCCAGCAGCCTATGCAGCCAAAC
CCTCATGGAAACATGATGTACACTGGCCCCTCCCATCACAGCTACATGAATGCTGCCGGCGTCC
CCAAGCAGTCACTTAATGGACCTTACATGAGAAGATGAGCGAGGTGAACTTGCAGTTAAAAGCT
TAAATATATATAAATAAAGGAACTTTTTATACTGACAAACCAGAGAAACAAATGGACCTTTTTT
CCAGTTAAAATATTACTGTAGACTTAGAGCAGTTTTTCTTTGGTTTATTATTATTATTATTACT
GTTTTTGTTTTGTTTTTAGAAAACCTGATCTCTTTTTGGGGGTTCGATTTTGTTTTCGGTTTTT
GTTTTCTTCACAATCTTGAACATTTTACAGTAGAACTCATCTAAAGATGGATTTGGGTAGGGGA
AACATGCACAAAATCTTTTCATAATTAAAAGGAGCCTTACTTTCTTTATATACCACATGGACAG
AATTGATGTAAACGTGAATTTATTTTTATTTTATGTATGTTTCCCCTCACTGTCTGCAGCTCCC
AGTTTTGTCATTTTTAAATGTTATATATACATCTCAAGAGTCAACCAGACCCTTTTCCTCCAAA
CCCTCCCTCCCTTCATTTCCCACTTCATTCCAGCAGGAGGCACTTAGGGGAACTGGGATGGGAA
CATGGAGAACAACCCAAGCTCCTTAAACTTAATGTTGTTGTTATTATTATTAATAAAGTGAAGC
AGGCAAAGCTTCTCCTTGTAAAATTCCCTCCCCTCCTCCCTACACACACACACACACACACACA
CACACACACACACACACACACACACACACACACACACACCCTCTGGAAACCTTTCCCCAAGAAT
GTTTCTAGGTAGACTTCATTAAAATTGTTTTTTCTTAATCAAGTGTAATATAATTCTTGTTTTT
TTTTTTTTTTAATCCCACTCAGCACTCAGAGACACAAAAATACTGTAAGTCTCACTTAACAGCA
GAATCTCAGAGGAAAGCTGTTTGCAATCCTCCTCCAGCCTTTGGAGGACACAGATGGTCAGCTA
ACAATCAGAAAGGGGACGACATGAACCTCTTGGTTTTTACCACCTGGTGAATCAGCCATAACAC
ACACACTCCACTCACCTCTTTAGTATGTACTTGGAAATGTGGACTAAGGGTCTTGTGCTTGCAC
CATTGACGCTGGTAACCTCAGAGCGAGCCCCTGTGATTTGCCTGTCGTATCTTACCCATAGTTT
CCATGAATGACTGTAGTACCAGCGACTTAGAAAACACCTGGTGCAGAAGGAGTCCCAAGGGAGA
CGATGGTGTGACTTCCGTAGCTGCATAAATGACGCATACCTCTCGTTGTCATGTTGTCTTGAGA
TCCTGAATTCATCCCCAAGAACCAGTGTGCACTAGCCCCTCTCCTGTGAGGATGAGCAAGGAGA
GACCCACCACCAGCATAGTAGGGCACAGCTGGCAGTAGGGCTTCAGGAGGCTCACATGTTGTCT
CACTAGTTTGCCCGTTCTCTTCCTACTTGCTCCAGGGATAGGTAAAAAGAAAAAAAAACTATAT
ATATAATTATAATTATATATATATTATATCTTCCATCATTAGAAGATGGAAACTATTATACCAC
TCGGTATGTGCAGTCAAATATCCAAAAGGAGGCCACAGTGCTTAAAAGACACCTGTAAGCATAG
AGCCTCTCCTCTATTTGTACATTTTATATAGATACATTTTTAAAGTACTAATTAGGCATTACAT
TTTTTCAAATGCACAGGTTTGTTGGGCTTTTTTATAGACCTTAATTGGCTTTCTCAATTAAGTG
TGTTAGATAGAAAAGCAGAACTTCACACTGTACTGCTATCAACTCTGAGCATGTGCAAGGCTGC
GTAGCACCCAGTTTCTCTGTATATACTGTTCCGGTTCCCCGTCATCTCTGTAGAATGTGCACCG
GCTGCCCTCTCCCACATCTTCAGCTATGTCATTGCTTCCTGGATGGGATGGGCAGGGATGGGAG
GGAGGGAAGGGAGGTCTGTGTGGGTGGAGGGTGGGTCAAGGCAGAAGGAGAAGCTGTTGAAATG
AGGGCCGTGAATTCACTTTCCGTTGGTTTGCAGTTGCGTTTGGGTTTCTTTGTTTCGTTATGTT
TTTAAATTCAGTCAGGCAGCTCCCTTTCCGCAGGCCTCTTTGTGACTGTAGAACTATTGTAGAA
AAAAAATACATTCTTTTCTATATTATAAAAGAAAATTATCCAACACGGTAATATTGGTACCTGT
CATTTTTTCACTTCTGTTTTAAAAAAAATGTTTTTTTAGCAAGATAACTTGGGTAATCTTCTAA
AAAAAAGAAATTTAAAACTCACTTGTTAGTGACTTTGATGCCTTTTAAAATAAGAGCTTTTTCA
TTTCATTCCATCTTTAAGATTTTTTATCTTTGTTGTAGAATATTAAAAACTATTTTAAGAAAGA
TAAAAATTCTCTTTAAAGAGATCTCTAGAGTGTGCGAATAGAGCTCCAGATGCCTCTAAAAGCC
GCATGTACAAACTAAGTCTATTCCTGTCTGTTTATATTTGCTTTTCCTGTTTTGTAACCTCTTT
GTACTTTGTTCCTGGTGACTTGTAAGCTGAGGGGAGGGGTGTCTAGACGCCTTTGTATTTCTCC
ATGTCATGCGCTCCTGGCCAGGTAGCCTCCCCTCCTCTCCTTGTATGTAATATCTTTTCCCCCT
TTCTAGCAAGTACTTTCAAAAGAACTCTGTACATTTTAACATAAAAAAATAAATTATGTTGAGC
CATTTTGGA

hide sequence

RefSeq Acc Id:

XM_039094586 ⟹ XP_038950514

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	75,787,411 - 75,868,584 (-)	NCBI
mRatBN7.2	16	69,084,914 - 69,165,923 (-)	NCBI

RefSeq Acc Id:

XM_039094587 ⟹ XP_038950515

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	75,787,411 - 75,868,411 (-)	NCBI
mRatBN7.2	16	69,084,921 - 69,165,902 (-)	NCBI

RefSeq Acc Id:

XM_063275455 ⟹ XP_063131525

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	75,787,411 - 75,816,464 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001094040	(Get FASTA)	NCBI Sequence Viewer
	XP_038950514	(Get FASTA)	NCBI Sequence Viewer
	XP_038950515	(Get FASTA)	NCBI Sequence Viewer
	XP_063131525	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAD72833	(Get FASTA)	NCBI Sequence Viewer
	EDM09023	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071789
	ENSRNOP00000071789.2
GenBank Protein	Q5TKR9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001094040 ⟸ NM_001100570

- UniProtKB:

Q5TKR9 (UniProtKB/Swiss-Prot), A6IW49 (UniProtKB/TrEMBL), A0A0G2K1C6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVKLANPLYTQWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVS
NKGLNSYKDPDNPGRIALPKPRNHGKLDNKQSVDWNKLLKRAFEGLAESGGSTLKSIERFLKSQ
KDVSAACGGTAASGFHQQLRLAIKRAVGHGRLLKDGPLYRLNTKAANAEGKEGCESLSCLPPVS
LLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEDLISCADCGNSGHPSCLKFSPELTVRVRALR
WQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKGRKLL
QKKAAQIKRRYANPIGRPKNRLKKQSTVSKGPFSKVRTGPGRGRKRKITVSSQSASSSEEGYLE
RIDGLDFCRDSSAPLKFNKKTKGLIDGLTKFFTPSPDGRKARGEAVDYSELRIRKKGNRKSSTS
HWPTDNQDGWESKQESEERLFGSQEIMTERDMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEF
GKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISV
FEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKY
NVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQ
NDKQISIKKLSKLTGVCPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVD
PECLRWTPVIVSNSVVSEEEDEEADDGEKEEPQGQERELETRERVGKSVSRENKDQDSSSLIES
EKKPEVKELASSSRLSKQALVRDSLPANSQPPRRGRCGRKNRKTQERFGDKDSKMLVGETLSTS
QEQYGECEEKSAASRERYTEVGEQPAAPQAQADGNPDIPKGRFSESADLWRGQLKKSPETLKCR
LPEGNDRLPCCYTDGDRAVFRGFSESSEEEEEPESPRSNSPPVLTKPTLKRKKPILHRRRRVRK
RKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIEEEEEEEDENELFPRGYFHCLS
SQDILRCQASSKRTASKDEEEEEEESDDADDTPVLKPVSLLRKCDVNSASLEPDTSTPMKKKKG
WPKGKSRKPIHWKKRPGRKPGFKLNQDIIAVSTQECIVEPIVPIKPGRKPRTQESEELVEVKEG
LVEERKEEMHTEADEEAEEEEDAASSDIRAMSPLDSSNSPDADPKEPEAEEEEEKPLDDPRQSE
EEPQELEEQEQEEEDEVTAEANQNEDHDADDEDDGHLDSLKTKEPEGQPAREDGTEEPGTQESF
LDASIQDSRENAKDKDETEADSEEEQPSHEASVGSETMPGSEEDHEEDSNTKEELIELKEEEEI
PHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTHTDEDPQMSMVEDCHASEH
NSPISSIPSHPSQSVRSVSSPSMPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQ
QVVDSGFSDLGSIESTTENYENPSSYDSTMGSSICGNNSSQSSCSYGGLSSSSSLTQNSCVVTQ
QMASMGNSCSMLQQNSVQPATNCNIKSPQTCVVERPPSNQQPPPPPPPPPPPQQPQPQPQQQAA
PQPPPPQPQQQPPPPPQQQPQPPPPPQQQPPLSQCSMNNSFTAAPMIMEIPESGGTGNISIYER
IPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSH
PLAGTPQAQATMTPPPNLAPTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSA
PLPSATAHQQQLYGRSPPAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYR
MTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAA
GVPKQSLNGPYMRR

hide sequence

Ensembl Acc Id:

ENSRNOP00000037279 ⟸ ENSRNOT00000037389

Ensembl Acc Id:

ENSRNOP00000071789 ⟸ ENSRNOT00000078743

RefSeq Acc Id:	XP_038950514 ⟸ XM_039094586
- Peptide Label:	isoform X1
- UniProtKB:	Q5TKR9 (UniProtKB/Swiss-Prot), A6IW49 (UniProtKB/TrEMBL), A0A0G2K1C6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038950515 ⟸ XM_039094587
- Peptide Label:	isoform X1
- UniProtKB:	Q5TKR9 (UniProtKB/Swiss-Prot), A6IW49 (UniProtKB/TrEMBL), A0A0G2K1C6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063131525 ⟸ XM_063275455
- Peptide Label:	isoform X2

Protein Domains

H15 MYST-type HAT PHD-type SAMD1-like winged helix (WH)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5TKR9-F1-model_v2	AlphaFold	Q5TKR9	1-1998	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700190

Promoter ID:

EPDNEW_R10706

Type:

multiple initiation site

Name:

Kat6a_1

Description:

lysine acetyltransferase 6A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	74,022,985 - 74,023,045	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304892	AgrOrtholog
BioCyc Gene	G2FUF-10893	BioCyc
Ensembl Genes	ENSRNOG00000025174	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000078743	ENTREZGENE
	ENSRNOT00000078743.2	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
	3.30.40.10	UniProtKB/Swiss-Prot
	3.40.630.30	UniProtKB/Swiss-Prot
	N-acetyl transferase-like	UniProtKB/Swiss-Prot
InterPro	Acyl_CoA_acyltransferase	UniProtKB/Swiss-Prot
	HAT_MYST-type	UniProtKB/Swiss-Prot
	Histone_H1/H5_H15	UniProtKB/Swiss-Prot
	MYST_HAT	UniProtKB/Swiss-Prot
	SAMD1-like_WH	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
	Zf-MYST	UniProtKB/Swiss-Prot
	Znf_FYVE_PHD	UniProtKB/Swiss-Prot
	Znf_PHD	UniProtKB/Swiss-Prot
	Znf_PHD-finger	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot
KEGG Report	rno:306571	UniProtKB/Swiss-Prot
NCBI Gene	306571	ENTREZGENE
PANTHER	HISTONE ACETYLTRANSFERASE	UniProtKB/Swiss-Prot
	PTHR10615:SF26	UniProtKB/Swiss-Prot
Pfam	MOZ_SAS	UniProtKB/Swiss-Prot
	PHD	UniProtKB/Swiss-Prot
	SAMD1_WH	UniProtKB/Swiss-Prot
	zf-MYST	UniProtKB/Swiss-Prot
PhenoGen	Kat6a	PhenoGen
PROSITE	H15	UniProtKB/Swiss-Prot
	MYST_HAT	UniProtKB/Swiss-Prot
	SAMD1_WH	UniProtKB/Swiss-Prot
	ZF_PHD_1	UniProtKB/Swiss-Prot
	ZF_PHD_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000025174	RatGTEx
SMART	H15	UniProtKB/Swiss-Prot
	PHD	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
	SSF55729	UniProtKB/Swiss-Prot
	SSF57903	UniProtKB/Swiss-Prot
UniProt	A0A0A0MY12_RAT	UniProtKB/TrEMBL
	A0A0G2K1C6	ENTREZGENE, UniProtKB/TrEMBL
	A6IW49	ENTREZGENE, UniProtKB/TrEMBL
	KAT6A_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Kat6a	lysine acetyltransferase 6A	Kat6a	K(lysine) acetyltransferase 6A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-02	Kat6a	K(lysine) acetyltransferase 6A	Myst3	MYST histone acetyltransferase (monocytic leukemia) 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Myst3	MYST histone acetyltransferase (monocytic leukemia) 3	Myst3_predicted	MYST histone acetyltransferase (monocytic leukemia) 3 (predicted)	Symbol and Name updated	1559027	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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