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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304892
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kat6a
Name: lysine acetyltransferase 6A
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kat6aaffects splicingEXP 6480464CTDValproic Acid affects the splicing of KAT6A mRNAPMID:29427782
Kat6adecreases expressionISOKAT6A (Homo sapiens)6480464CTDValproic Acid results in decreased expression of KAT6A mRNAPMID:23179753 PMID:24935251 PMID:28001369
Kat6adecreases methylationISOKAT6A (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of KAT6A genePMID:29154799
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