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Gene: LOC101954950 (aromatase) Ictidomys tridecemlineatus

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Symbol:

LOC101954950 (Ensembl: CYP19A1)

Name:

aromatase (Ensembl:cytochrome P450 family 19 subfamily A member 1)

RGD ID:

12553027

Description:

ENCODES a protein that exhibits aromatase activity (ortholog); oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (ortholog); INVOLVED IN adrenal gland development (ortholog); androgen metabolic process (ortholog); bile acid metabolic process (ortholog); PARTICIPATES IN aromatase inhibitor pathway; estradiol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Alzheimer's disease (ortholog); amenorrhea (ortholog); FOUND IN axon terminus (ortholog); dendritic spine (ortholog); neuronal cell body (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	95,258,165 - 95,328,751 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	13,107,603 - 13,136,910 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	13,107,603 - 13,136,910 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenocarcinoma (ISO)

Alzheimer's disease (ISO)

amenorrhea (ISO)

aromatase excess syndrome (ISO)

autism spectrum disorder (ISO)

autistic disorder (ISO)

bladder neck obstruction (ISO)

Bloom syndrome (ISO)

bone resorption disease (ISO)

breast cancer (ISO)

Breast Neoplasms (ISO)

chronic obstructive pulmonary disease (ISO)

colorectal cancer (ISO)

Congenital Adrenal Hyperplasia due to 21 Hydroxylase Deficiency (ISO)

Critical Illness (ISO)

Diabetic Nephropathies (ISO)

endometrial cancer (ISO)

endometriosis (ISO)

Esophageal Neoplasms (ISO)

esophagus adenocarcinoma (ISO)

Experimental Diabetes Mellitus (ISO)

Female Infertility (ISO)

Fibrosis (ISO)

genetic disease (ISO)

gestational diabetes (ISO)

hypertension (ISO)

hypogonadism (ISO)

hypopituitarism (ISO)

hypothyroidism (ISO)

Kidney Reperfusion Injury (ISO)

Knee Osteoarthritis (ISO)

Neoplasm Metastasis (ISO)

osteoporosis (ISO)

ovarian cancer (ISO)

ovarian disease (ISO)

paraplegia (ISO)

placental insufficiency (ISO)

polycystic ovary syndrome (ISO)

Postmenopausal Osteoporosis (ISO)

primary ovarian insufficiency (ISO)

prostate carcinoma in situ (ISO)

Prostatic Neoplasms (ISO)

prostatitis (ISO)

protein-energy malnutrition (ISO)

Recurrence (ISO)

Reperfusion Injury (ISO)

Sexual Infantilism (ISO)

Sjogren's syndrome (ISO)

steatotic liver disease (ISO)

Tissue Adhesions (ISO)

urethral obstruction (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adrenal gland development (ISO)

androgen catabolic process (IEA)

androgen metabolic process (IEA,ISO)

bile acid metabolic process (ISO)

biphenyl metabolic process (ISO)

bone development (ISO)

C21-steroid hormone metabolic process (ISO)

calcineurin-mediated signaling (ISO)

cellular response to fibroblast growth factor stimulus (ISO)

cellular response to follicle-stimulating hormone stimulus (ISO)

cellular response to glucose stimulus (ISO)

cellular response to gonadotropin stimulus (ISO)

cellular response to hydrostatic pressure (ISO)

estrogen biosynthetic process (ISO)

female genitalia development (IEA,ISO)

female gonad development (IEA,ISO)

granulocyte differentiation (ISO)

hippocampus development (ISO)

hypothalamus development (ISO)

luteinization (ISO)

male gonad development (ISO)

mammary gland development (IEA,ISO)

melatonin metabolic process (ISO)

negative regulation of bone resorption (ISO)

negative regulation of chronic inflammatory response (IEA,ISO)

negative regulation of macrophage chemotaxis (IEA,ISO)

phthalate metabolic process (ISO)

positive regulation of estradiol secretion (IEA)

prostate gland growth (IEA,ISO)

regulation of synapse structure or activity (ISO)

response to 2,3,7,8-tetrachlorodibenzodioxine (ISO)

response to cesium ion (ISO)

response to estradiol (IEA,ISO)

response to estrogen (ISO)

response to herbicide (ISO)

response to ionizing radiation (ISO)

response to metal ion (ISO)

response to testosterone (ISO)

response to xenobiotic stimulus (ISO)

testosterone biosynthetic process (IEA,ISO)

uterus development (IEA,ISO)

Cellular Component

axon terminus (ISO)

dendritic spine (ISO)

endoplasmic reticulum (IEA)

membrane (IEA)

neuronal cell body (ISO)

synaptic vesicle (ISO)

terminal bouton (ISO)

Molecular Function

aromatase activity (IEA,ISO)

heme binding (IEA)

iron ion binding (IEA)

metal ion binding (IEA)

monooxygenase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

aromatase inhibitor pathway (ISO)

estradiol biosynthetic pathway (ISO)

steroid hormone biosynthetic pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

LOC101954950
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	95,258,165 - 95,328,751 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	13,107,603 - 13,136,910 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	13,107,603 - 13,136,910 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYP19A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	51,208,057 - 51,338,596 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	51,208,057 - 51,338,601 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	51,500,254 - 51,630,793 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	49,288,961 - 49,418,086 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	15	28,393,650 - 28,524,194 (-)	NCBI		Celera
Cytogenetic Map	15	q21.2	NCBI
HuRef	15	28,330,314 - 28,460,872 (-)	NCBI		HuRef
CHM1_1	15	51,618,344 - 51,748,904 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	49,015,801 - 49,146,366 (-)	NCBI		T2T-CHM13v2.0

Cyp19a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	54,073,221 - 54,175,448 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	54,073,221 - 54,175,394 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	54,165,937 - 54,268,164 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	54,165,937 - 54,268,110 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	54,013,744 - 54,041,249 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	53,964,074 - 53,991,581 (-)	NCBI		MGSCv36	mm8
Celera	9	51,408,025 - 51,435,376 (-)	NCBI		Celera
Cytogenetic Map	9	A5.3	NCBI
cM Map	9	29.49	NCBI

Cyp19a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	63,449,148 - 63,476,534 (-)	NCBI		GRCr8
mRatBN7.2	8	54,552,978 - 54,580,375 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	54,553,165 - 54,580,758 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	60,087,103 - 60,114,553 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	58,366,113 - 58,393,560 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	56,230,358 - 56,257,810 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	58,744,849 - 58,772,408 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	58,744,849 - 58,772,408 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	57,321,085 - 57,348,481 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	8	57,671,013 - 57,691,109 (-)	NCBI
Celera	8	54,044,272 - 54,071,684 (-)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

LOC102023780
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	3,266,233 - 3,313,142 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	3,198,622 - 3,313,072 (+)	NCBI	ChiLan1.0	ChiLan1.0

CYP19A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	40,450,148 - 40,558,353 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	44,628,633 - 44,758,666 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	30,152,924 - 30,282,854 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	48,486,688 - 48,616,347 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	48,486,688 - 48,521,554 (-)	Ensembl	panpan1.1		panPan2

CYP19A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	16,954,020 - 17,056,728 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	16,957,215 - 16,988,353 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	16,883,348 - 16,914,898 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	17,098,681 - 17,221,672 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	17,101,433 - 17,133,428 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	17,024,100 - 17,055,822 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	17,141,587 - 17,173,348 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	17,248,285 - 17,280,035 (-)	NCBI		UU_Cfam_GSD_1.0

CYP19A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	120,367,667 - 120,695,899 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	120,652,172 - 120,695,899 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	133,903,926 - 133,936,093 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CYP19A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	32,074,260 - 32,164,926 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	32,132,425 - 32,164,277 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	109,028,218 - 109,061,355 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101702005
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	9,053,803 - 9,100,212 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	9,053,644 - 9,100,212 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005316566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000006005 ⟹ ENSSTOP00000005373

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936471	13,107,603 - 13,136,910 (-)	Ensembl

RefSeq Acc Id:

XM_005316566 ⟹ XP_005316623

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	95,258,165 - 95,288,847 (-)	NCBI
SpeTri2.0	NW_004936471	13,107,603 - 13,136,910 (-)	NCBI

Sequence:

show sequence

ATTGCTGTGTCTGAGGCTGATGAGAGCAAGATGGTTTTGGAAATGCTGAATCCAATGCACTATA
ATGTCACCAGCATAGTGCCAGAAGTCATACATGTTGGCACCATGCCGATTCTGCTGCTCATGGG
CCTTCTTCTCTTGATTTGGAATTATGAGAACACATCTTCAATACCAGGTCCTGGATACTGTATG
GGAATTGGGCCCCTCATTTCCCATGGTAGATTCCTGTGGATGGGGATTGGCAGTGCCTGCAACT
ACTACAACAAGATGTATGGAGAATTCATGAGAGTCTGGATAGGTGGAGAAGAAACACTCATTAT
CAGCAAGTCCTCAAGTATGTTCCATGTAATGAAGCACAGTCACTACATCTCTCGATTTGGCAGC
AAACTTGGGTTGCAGTGCATTGGTATGCATGAGAATGGCATCATATTTAACAATAATCCAGACG
TCTGGAGAGCAGTACGACCTTTTTTTATGAAAGCTTTGACAGGCCCTGGCCTTGTTCGAATGGT
GGCAGTTTGTGCTGAATCCATCATAAGGCACCTGGACAGACTGGAGGAGGTCACCAATATGTCG
GGCTACATTGACGTGTTGACCCTCATGCGGCGCATCATGCTGGACACCTCTAATATGCTTTTCT
TGGGGATTCCCTTGGACGAAAGTGCCATCGTGGATAAAATCCAGGGTTATTTTGATGCATGGCA
GGCTCTCCTTCTCAAGCCAAACATCTTCTTTAAGATTTCTTGGCTATACAAAAAATATGAAAAG
CCTGTCAAGGATTTGAAAGATGCCATAAATATTTTGGTAGAAGAAAAAAGGCAAAAGGTTTCCA
CAGCAGAGAAGCTAGAAGACTGTATGGATTTTGCCACTGAATTGATTTTTGCTGAGAAACGTGG
AGATCTGACAAGAGAGAATGTGAACCAGTGCATATTGGAAATGCTGATTGCAGCACCTGACACT
ATGTCTGTCACTGTGTACTTCATGCTGTTCCTCATTGCAAATCACCCTAAAGTTGAAGAGGCAA
TAATGAAGGAAATACAGACTGTTGTTGGTGAAAGAGAGATAAAGATTGACGATGTGCAAAAACT
AAAAGTGATGGAAAACTTCATTTACGAGAGCCTGCGGTACCAGCCCGTCGTGGACTTGGTGATG
CGCAAAGCCTTACAAGATGATGTGATTGACGGCTACCCCGTGAAAAAGGGAACTAACATTATTC
TGAATATTGGAAGAATGCATCGACTCGAGTTTTTCCCCAAGCCTAACGAATTTACTCTTGAAAA
TTTTGAGAAGAATGTTCCTTACAGGTATTTTCAGCCATTTGGCTTTGGGCCCCGCAGCTGTGCA
GGAAAGTACATTGCCATGGTGATGATGAAAGTTGTCCTGGTTACACTTCTGAGGCGATTCCATG
TGAAGACATTGCAAGGAAAGTGTGTTGAAAACATACAGAAGAGAAATGACTTGTCCTTGCACCC
AGATGAAACAAGTGATCTGCTAGAAATGATTTTTACCCCAAGAAATTCAGACAAGTGCATCAAA
CACTAAAGAAGGTTGTTCAGTGACTACTCTGGAACATTTCTCATCAGTAGCTCACAT

hide sequence

RefSeq Acc Id:

XM_040275481 ⟹ XP_040131415

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	95,259,540 - 95,328,751 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005316623	(Get FASTA)	NCBI Sequence Viewer
	XP_040131415	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000005373.2
GenBank Protein	KAG3261864	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005316623 ⟸ XM_005316566

- UniProtKB:

I3M742 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVLEMLNPMHYNVTSIVPEVIHVGTMPILLLMGLLLLIWNYENTSSIPGPGYCMGIGPLISHGR
FLWMGIGSACNYYNKMYGEFMRVWIGGEETLIISKSSSMFHVMKHSHYISRFGSKLGLQCIGMH
ENGIIFNNNPDVWRAVRPFFMKALTGPGLVRMVAVCAESIIRHLDRLEEVTNMSGYIDVLTLMR
RIMLDTSNMLFLGIPLDESAIVDKIQGYFDAWQALLLKPNIFFKISWLYKKYEKPVKDLKDAIN
ILVEEKRQKVSTAEKLEDCMDFATELIFAEKRGDLTRENVNQCILEMLIAAPDTMSVTVYFMLF
LIANHPKVEEAIMKEIQTVVGEREIKIDDVQKLKVMENFIYESLRYQPVVDLVMRKALQDDVID
GYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFEKNVPYRYFQPFGFGPRSCAGKYIAMVMMK
VVLVTLLRRFHVKTLQGKCVENIQKRNDLSLHPDETSDLLEMIFTPRNSDKCIKH

hide sequence

RefSeq Acc Id:	XP_040131415 ⟸ XM_040275481
- UniProtKB:	I3M742 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000005373 ⟸ ENSSTOT00000006005

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000006011	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000006005.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
	Cytochrome_P450_Monoox	UniProtKB/TrEMBL
NCBI Gene	LOC101954950	ENTREZGENE
PANTHER	AROMATASE	UniProtKB/TrEMBL
	CYTOCHROME P450 FAMILY 4	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450I	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	I3M742	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

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