NPPA (natriuretic peptide A) - Rat Genome Database

Name: NPPA
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: NPPA (natriuretic peptide A) Canis lupus familiaris

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Symbol:

NPPA

Name:

natriuretic peptide A

RGD ID:

12252074

Description:

ENCODES a protein that exhibits hormone activity (ortholog); neuropeptide hormone activity (ortholog); neuropeptide receptor binding (ortholog); INVOLVED IN cardiac muscle hypertrophy in response to stress (ortholog); cell growth involved in cardiac muscle cell development (ortholog); cellular response to angiotensin (ortholog); PARTICIPATES IN atrial natriuretic peptide signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); adenocarcinoma (ortholog); FOUND IN brush border (ortholog); cytoplasm (ortholog); extracellular space (ortholog); INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; dexamethasone

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ANF; ANP; atrial natriuretic factor; atrial natriuretic factor prohormone; atrial natriuretic peptide; atrial natriuretic peptide prohormone; atriopeptigen; cardiodilatin; CDD; natriuretic peptide precursor A; natriuretic peptides A; preproANF; preproANP; preproCDD-ANF; prepronatriodilatin; proANF; proANP

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NPPA (natriuretic peptide A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nppa (natriuretic peptide type A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nppa (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nppa (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NPPA (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nppa (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NPPA (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NPPA (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nppa (natriuretic peptide A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NPPB (natriuretic peptide B)	HGNC	EggNOG, Inparanoid

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	84,406,317 - 84,408,115 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	84,396,073 - 84,408,385 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	80,939,561 - 80,941,359 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	85,071,241 - 85,073,039 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	85,060,271 - 85,073,309 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	81,819,847 - 81,821,645 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	82,819,771 - 82,821,568 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	83,882,545 - 83,884,343 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

Acute Lung Injury (ISO)

adenocarcinoma (ISO)

aortic valve insufficiency (ISO)

Atrial Dilation and Standstill (ISO)

atrial standstill 1 (ISO)

atrial standstill 2 (ISO)

brain ischemia (ISO)

Cardiac Arrhythmias (ISO)

Cardiomegaly (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

chromosome 1p36 deletion syndrome (ISO)

chronic kidney disease (ISO)

congestive heart failure (ISO)

Contrast-Induced Nephropathy (ISO)

coronary artery disease (ISO)

coronary stenosis (ISO)

Diabetic Cardiomyopathies (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

Diaphragmatic Hernia (ISO)

diastolic heart failure (ISO)

dilated cardiomyopathy (ISO)

Ehlers-Danlos syndrome kyphoscoliotic type 1 (ISO)

Experimental Diabetes Mellitus (ISO)

Familial Atrial Fibrillation 6 (ISO)

genetic disease (ISO)

glomerulonephritis (ISO)

heart disease (ISO)

Hypercapnia (ISO)

hypertension (ISO)

hypertrophic cardiomyopathy (ISO)

Hypotension (ISO)

Hypoxia (ISO)

intrinsic cardiomyopathy (ISO)

Kidney Reperfusion Injury (ISO)

Left Ventricular Hypertrophy (ISO)

liver cirrhosis (ISO)

Lung Neoplasms (ISO)

melanoma (ISO)

Metabolic Side Effects of Drugs and Substances (ISO)

myocardial infarction (ISO)

Myocardial Ischemia (ISO)

Neoplasm Metastasis (ISO)

nephrosis (ISO)

obesity (ISO)

Pain (ISO)

patent ductus arteriosus (ISO)

peritonitis (ISO)

Prostatic Neoplasms (ISO)

pulmonary hypertension (ISO)

renal hypertension (ISO)

Right Ventricular Hypertrophy (ISO)

Skin Neoplasms (ISO)

small cell carcinoma (ISO)

Stroke (ISO)

Transplant Rejection (ISO)

type 2 diabetes mellitus (ISO)

ureteral obstruction (ISO)

Urination Disorders (ISO)

vascular dementia (ISO)

Ventricular Remodeling (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R)-adrenaline (EXP)

(R)-noradrenaline (EXP)

dexamethasone (EXP)

enalapril (EXP)

propranolol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood vessel diameter maintenance (IEA)

cardiac muscle hypertrophy in response to stress (ISO)

cell growth involved in cardiac muscle cell development (ISO)

cellular response to angiotensin (ISO)

cellular response to hydrogen peroxide (ISO)

cellular response to mechanical stimulus (ISO)

cGMP biosynthetic process (IBA,ISO,ISS)

cGMP-mediated signaling (IBA,ISO)

female pregnancy (ISS)

negative regulation of blood pressure (ISO)

negative regulation of canonical Wnt signaling pathway (ISO)

negative regulation of cell growth (ISO)

negative regulation of collecting lymphatic vessel constriction (ISO)

negative regulation of epidermal growth factor receptor signaling pathway (ISO)

negative regulation of JUN kinase activity (ISO)

negative regulation of systemic arterial blood pressure (IBA,ISO)

neuropeptide signaling pathway (IBA)

positive regulation of cardiac muscle contraction (ISO)

positive regulation of cGMP-mediated signaling (ISO)

positive regulation of delayed rectifier potassium channel activity (ISO)

positive regulation of heart rate (ISO)

positive regulation of histamine secretion by mast cell (ISO)

positive regulation of potassium ion export across plasma membrane (ISO)

protein folding (ISO)

receptor guanylyl cyclase signaling pathway (IBA,ISO,ISS)

regulation of atrial cardiac muscle cell membrane repolarization (ISO)

regulation of blood pressure (ISS)

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ISO)

regulation of high voltage-gated calcium channel activity (ISO)

response to 3-methylcholanthrene (ISO)

response to hypoxia (ISO)

response to insulin (ISO)

signal transduction (IEA)

sodium ion export across plasma membrane (ISO)

synaptic signaling via neuropeptide (ISO)

system process (IEA)

vasodilation (IEA)

Cellular Component

brush border (ISO)

cell projection (IEA)

cytoplasm (IBA,ISO)

extracellular region (IEA)

extracellular space (IBA,ISO)

glycinergic synapse (ISO)

mast cell granule (ISO)

perikaryon (IEA)

perinuclear region of cytoplasm (ISO)

protein-containing complex (ISO)

Molecular Function

hormone activity (IBA,IEA,ISO)

hormone receptor binding (IBA)

neuropeptide hormone activity (ISO)

neuropeptide receptor binding (ISO)

protein binding (ISO)

signaling receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

atrial natriuretic peptide signaling pathway (ISO)

References

Additional References at PubMed

PMID:2934062	PMID:15838287	PMID:17338155	PMID:18681918	PMID:19585255	PMID:21835711	PMID:22301074	PMID:22578688	PMID:30032202

Genomics

Comparative Map Data

NPPA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	84,406,317 - 84,408,115 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	84,396,073 - 84,408,385 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	80,939,561 - 80,941,359 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	85,071,241 - 85,073,039 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	85,060,271 - 85,073,309 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	81,819,847 - 81,821,645 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	82,819,771 - 82,821,568 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	83,882,545 - 83,884,343 (+)	NCBI		UU_Cfam_GSD_1.0

NPPA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	11,845,709 - 11,847,783 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	11,845,709 - 11,848,345 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	11,905,766 - 11,907,840 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	11,828,363 - 11,830,422 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	11,840,041 - 11,842,101	NCBI
Celera	1	11,019,389 - 11,021,472 (-)	NCBI		Celera
Cytogenetic Map	1	p36.22	NCBI
HuRef	1	11,060,823 - 11,062,905 (-)	NCBI		HuRef
CHM1_1	1	11,893,660 - 11,895,736 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	11,389,795 - 11,391,868 (-)	NCBI		T2T-CHM13v2.0

Nppa
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	148,085,179 - 148,086,531 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	148,085,179 - 148,086,536 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	148,000,722 - 148,002,074 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	148,000,722 - 148,002,079 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	147,374,855 - 147,376,176 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	146,844,546 - 146,845,867 (+)	NCBI		MGSCv36	mm8
Celera	4	150,267,117 - 150,268,440 (+)	NCBI		Celera
Cytogenetic Map	4	E1	NCBI
cM Map	4	78.66	NCBI

Nppa
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	163,712,184 - 163,713,493 (+)	NCBI		GRCr8
mRatBN7.2	5	158,429,042 - 158,430,351 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	158,429,042 - 158,430,351 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	161,145,793 - 161,147,102 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	162,973,730 - 162,975,039 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	162,930,077 - 162,931,386 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	164,808,407 - 164,809,716 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	164,808,323 - 164,809,705 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	168,466,309 - 168,467,618 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	165,074,518 - 165,075,827 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	165,084,713 - 165,086,000 (+)	NCBI
Celera	5	156,710,885 - 156,712,194 (+)	NCBI		Celera
RH 3.4 Map	5	1106.6	RGD
Cytogenetic Map	5	q36	NCBI

Nppa
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	2,060,735 - 2,063,003 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	2,061,196 - 2,062,805 (+)	NCBI	ChiLan1.0	ChiLan1.0

NPPA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	216,375,951 - 216,382,131 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	215,021,064 - 215,023,807 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	10,608,025 - 10,610,287 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	11,825,072 - 11,827,452 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	11,825,072 - 11,827,373 (-)	Ensembl	panpan1.1		panPan2

Nppa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	34,846,575 - 34,848,291 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936474	671,362 - 673,610 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NPPA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	71,918,845 - 71,921,405 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	71,919,557 - 71,921,345 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	65,829,057 - 65,830,990 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NPPA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	119,942,412 - 119,946,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	119,944,532 - 119,945,917 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	23,811,217 - 23,814,235 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nppa
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	1,147,974 - 1,148,927 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	1,147,654 - 1,149,722 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NPPA
36 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001313851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000026188 ⟹ ENSCAFP00000024316

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	84,396,073 - 84,408,385 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000026190 ⟹ ENSCAFP00000024318

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	84,406,317 - 84,408,115 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000082103 ⟹ ENSCAFP00000053231

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	84,406,317 - 84,407,306 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003487 ⟹ ENSCAFP00845002767

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	85,060,271 - 85,073,309 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003490 ⟹ ENSCAFP00845002768

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	85,060,271 - 85,062,005 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003501 ⟹ ENSCAFP00845002777

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	85,071,241 - 85,073,039 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003507 ⟹ ENSCAFP00845002782

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	85,071,241 - 85,072,230 (+)	Ensembl

RefSeq Acc Id:

NM_001313851 ⟹ NP_001300780

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	84,406,317 - 84,408,115 (+)	NCBI
Dog10K_Boxer_Tasha	2	80,939,561 - 80,941,359 (+)	NCBI
ROS_Cfam_1.0	2	85,071,241 - 85,073,039 (+)	NCBI
UMICH_Zoey_3.1	2	81,819,847 - 81,821,645 (+)	NCBI
UNSW_CanFamBas_1.0	2	82,819,771 - 82,821,568 (+)	NCBI
UU_Cfam_GSD_1.0	2	83,882,545 - 83,884,343 (+)	NCBI

Sequence:

show sequence

CTGCAAGTGACAGAATGGGGAGGGTTCCGTCCCTCTTGTGCTCTTGGAGAGCCGGGGGGCTATA
AAAAGAGGAGGCGCAGGGCAGCTGGGAGACAGAGGCAGACGGAGGCTGAGAGAGGGAGGCGAGA
GGACAGGGGAGCAGCAAGCACCGGGCCACTCCTCGAGCGACGCCAGCATGGGCTCCCCCATCGC
CGCAAGCTTCCTCCTCTTCTTGGCAGTTCAGCTCCTGGGGCAGACGGGCGCTAACCCCGTGTAC
GGCTCTGTGTCCAATGCAGACCTGCTGGATTTCAAGAACTTGCTGGACCGCTTGGAGGACAAGA
TGCCTTTAGAAGATGAAGCCGAGTCTCCCCAAGCCCTGAGTGAGCAGAATGCGGAAGCTGGGGC
AGCTCTCAGCCCCCTGCCTGAGGTGCCTCCCTGGACGGGGGAGGTCAGCCCAGCCCAGAGAGAT
GGGGGTGCCCTTGGGCGCAGCCCCTGGGACTCCTCCGATAGATCTGCCCTCCTGAAGAGCAAGC
TGAGAGCCCTGCTTGCTGCCCCTCGGAGCCTGCGGAGGTCCAGCTGCTTCGGAGGCAGGATGGA
TAGGATTGGAGCCCAGAGCGGACTGGGCTGCAACAGCTTCCGGTACTGAAGATAATGGCCAGGG
AGGAAAAGGAGGCCCTGGCCCGGGGGCAGACTCTGAGAGACCCTCGTCCCTTGGGGTCTCTCAC
TCAACTTTGTCCCAGCTCATTGCCATCAAGTTGAGCCGTGACGAGCACCGAGACCGTATTCAAG
CTGCAGCCTCTTGGCGATGTTTCTCACGTTCTATGCTAAACGTAGATAACTTGGCTGAATTGTG
GCTTTCCCACCCCTCCCACCCCACGCGTTAACAGTTTAGCATAGACACTCACCTGTTACTGAAA
GGGGTTTGAAAACCAATAAACTTCAGCACCACGGACAGCAGCCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001300780	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000024316.4
	ENSCAFP00000024318.3
	ENSCAFP00000053231.1
	ENSCAFP00030027196.1
	ENSCAFP00040009498.1
	ENSCAFP00040009516.1
	ENSCAFP00040009532.1
	ENSCAFP00805003864
	ENSCAFP00845002767.1
	ENSCAFP00845002777
	ENSCAFP00845002777.1
	ENSCAFP00845002782.1
GenBank Protein	P07499	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001300780 ⟸ NM_001313851
- Peptide Label:	precursor
- UniProtKB:	P07499 (UniProtKB/Swiss-Prot), A0A8C0NNC8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSPIAASFLLFLAVQLLGQTGANPVYGSVSNADLLDFKNLLDRLEDKMPLEDEAESPQALSEQ NAEAGAALSPLPEVPPWTGEVSPAQRDGGALGRSPWDSSDRSALLKSKLRALLAAPRSLRRSSC FGGRMDRIGAQSGLGCNSFRY hide sequence

Ensembl Acc Id:

ENSCAFP00000053231 ⟸ ENSCAFT00000082103

Ensembl Acc Id:

ENSCAFP00000024316 ⟸ ENSCAFT00000026188

Ensembl Acc Id:

ENSCAFP00000024318 ⟸ ENSCAFT00000026190

Ensembl Acc Id:

ENSCAFP00845002782 ⟸ ENSCAFT00845003507

Ensembl Acc Id:

ENSCAFP00845002777 ⟸ ENSCAFT00845003501

Ensembl Acc Id:

ENSCAFP00845002768 ⟸ ENSCAFT00845003490

Ensembl Acc Id:

ENSCAFP00845002767 ⟸ ENSCAFT00845003487

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000016539	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSCAFG00030016767	UniProtKB/TrEMBL
	ENSCAFG00040005849	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSCAFG00805002757	UniProtKB/Swiss-Prot
	ENSCAFG00845001994	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000026188.5	UniProtKB/TrEMBL
	ENSCAFT00000026190.5	UniProtKB/Swiss-Prot
	ENSCAFT00000082103.2	UniProtKB/TrEMBL
	ENSCAFT00030031168.1	UniProtKB/TrEMBL
	ENSCAFT00040010954.1	UniProtKB/TrEMBL
	ENSCAFT00040010974.1	UniProtKB/Swiss-Prot
	ENSCAFT00040010994.1	UniProtKB/TrEMBL
	ENSCAFT00805005044	UniProtKB/Swiss-Prot
	ENSCAFT00845003487.1	UniProtKB/TrEMBL
	ENSCAFT00845003501	ENTREZGENE
	ENSCAFT00845003501.1	UniProtKB/Swiss-Prot
	ENSCAFT00845003507.1	UniProtKB/TrEMBL
InterPro	Natr_peptide	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Natr_peptide_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Natriuretic_peptide	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Natriuretic_peptide_atrial	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Natriuretic_peptide_brain	UniProtKB/TrEMBL
KEGG Report	cfa:608289	UniProtKB/Swiss-Prot
NCBI Gene	NPPA	ENTREZGENE
PANTHER	ATRIAL NATRIURETIC FACTOR PRECURSOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NATRIURETIC PEPTIDES A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NATRIURETIC PEPTIDES B	UniProtKB/TrEMBL
Pfam	ANP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	ANATPEPTIDE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BNATPEPTIDE	UniProtKB/TrEMBL
	NATPEPTIDES	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	NATRIURETIC_PEPTIDE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	NAT_PEP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0NNC8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Q7W5_CANLF	UniProtKB/TrEMBL
	A0A8C0QEJ9_CANLF	UniProtKB/TrEMBL
	A0A8I3MJH6_CANLF	UniProtKB/TrEMBL
	A0A8I3MJW9_CANLF	UniProtKB/TrEMBL
	A0A8P0NI44_CANLF	UniProtKB/TrEMBL
	A0A8P0P2U9_CANLF	UniProtKB/TrEMBL
	ANF_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:43925	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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