Symbol:
ATP2A2
Name:
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
RGD ID:
12087520
Description:
ENCODES a protein that exhibits ATP binding (ortholog); calcium ion binding (ortholog); lutropin-choriogonadotropic hormone receptor binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); autophagosome membrane docking (ortholog); calcium ion transmembrane transport (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); acrokeratosis verruciformis (ortholog); Acute Experimental Pancreatitis (ortholog); FOUND IN apical ectoplasmic specialization (ortholog); calcium ion-transporting ATPase complex (ortholog); extrinsic component of cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH enalapril; metoprolol; ranolazine
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
calcium ATPase; calcium pump 2; calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; sarcoplasmic reticulum Ca2+-transport ATPase isoform; sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SERCA2A; SR Ca(2+)-ATPase 2
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):
Atp2a2 (ATPase, Ca++ transporting, cardiac muscle, slow twitch 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):
Atp2a2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Atp2a2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Atp2a2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Atp2a2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Latest Assembly:
CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 26 8,148,181 - 8,209,392 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 26 8,148,236 - 8,209,388 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 26 8,312,735 - 8,373,567 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 26 8,406,466 - 8,467,508 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 26 8,406,107 - 8,467,504 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 26 8,366,182 - 8,427,199 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 26 8,424,775 - 8,485,590 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 26 8,381,368 - 8,442,436 (+) NCBI UU_Cfam_GSD_1.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - SMPDB
Biological Process
autophagosome assembly (IBA,IEA,ISS) autophagosome membrane docking (IEA,ISS) calcium ion import into sarcoplasmic reticulum (IEA) calcium ion transmembrane transport (IBA,IEA,ISS) calcium ion transport (IEA,ISO) calcium ion transport from cytosol to endoplasmic reticulum (IEA) cardiac muscle hypertrophy in response to stress (IEA) cellular response to heat (ISO) cellular response to oxidative stress (IEA) endoplasmic reticulum calcium ion homeostasis (IEA) ER-nucleus signaling pathway (IEA) intracellular calcium ion homeostasis (IBA,IEA) mitochondrion-endoplasmic reticulum membrane tethering (IEA,ISS) monoatomic ion transport (IEA) negative regulation of heart contraction (IEA) neuron cellular homeostasis (IEA) organelle localization by membrane tethering (IEA,ISS) positive regulation of cardiac muscle cell apoptotic process (IEA) positive regulation of endoplasmic reticulum calcium ion concentration (IEA) regulation of calcium ion-dependent exocytosis of neurotransmitter (IEA) regulation of cardiac muscle cell action potential involved in regulation of contraction (ISO) regulation of cardiac muscle cell membrane potential (IEA) regulation of cardiac muscle contraction by calcium ion signaling (IBA) regulation of the force of heart contraction (IEA) relaxation of cardiac muscle (ISO) relaxation of skeletal muscle (ISO) response to endoplasmic reticulum stress (ISO) response to lipopolysaccharide (ISO) response to peptide hormone (ISO) sarcoplasmic reticulum calcium ion transport (IEA,ISO) T-tubule organization (IEA) transition between fast and slow fiber (IEA)
ATP2A2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 26 8,148,181 - 8,209,392 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 26 8,148,236 - 8,209,388 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 26 8,312,735 - 8,373,567 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 26 8,406,466 - 8,467,508 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 26 8,406,107 - 8,467,504 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 26 8,366,182 - 8,427,199 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 26 8,424,775 - 8,485,590 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 26 8,381,368 - 8,442,436 (+) NCBI UU_Cfam_GSD_1.0
ATP2A2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 12 110,280,616 - 110,351,093 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 12 110,280,756 - 110,351,093 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 12 110,718,421 - 110,788,898 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 12 109,203,815 - 109,273,278 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 12 109,182,151 - 109,251,615 NCBI Celera 12 110,344,773 - 110,414,642 (+) NCBI Celera Cytogenetic Map 12 q24.11 NCBI HuRef 12 107,737,670 - 107,807,502 (+) NCBI HuRef CHM1_1 12 110,686,837 - 110,756,707 (+) NCBI CHM1_1 T2T-CHM13v2.0 12 110,258,258 - 110,328,744 (+) NCBI T2T-CHM13v2.0
Atp2a2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 5 122,591,576 - 122,640,288 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 5 122,591,576 - 122,640,288 (-) Ensembl GRCm39 Ensembl GRCm38 5 122,453,513 - 122,502,225 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 5 122,453,513 - 122,502,225 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 5 122,903,522 - 122,952,234 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 5 122,714,131 - 122,762,512 (-) NCBI MGSCv36 mm8 Celera 5 119,532,083 - 119,580,718 (-) NCBI Celera Cytogenetic Map 5 F NCBI cM Map 5 62.38 NCBI
Atp2a2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 39,733,519 - 39,782,942 (+) NCBI GRCr8 mRatBN7.2 12 34,072,710 - 34,122,142 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 34,072,683 - 34,122,101 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 12 35,245,140 - 35,294,551 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 12 35,856,569 - 35,905,979 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 12 34,908,881 - 34,958,289 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 12 39,553,903 - 39,603,326 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 39,553,903 - 39,603,326 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 12 41,434,651 - 41,482,924 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 12 35,266,600 - 35,316,237 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 12 35,129,987 - 35,179,584 (+) NCBI Celera 12 35,744,606 - 35,793,364 (+) NCBI Celera Cytogenetic Map 12 q16 NCBI
Atp2a2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955482 7,233,336 - 7,295,754 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955482 7,233,336 - 7,295,754 (+) NCBI ChiLan1.0 ChiLan1.0
ATP2A2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 10 118,347,938 - 118,415,869 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 12 118,344,305 - 118,412,270 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 12 107,857,009 - 107,924,938 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 12 111,249,039 - 111,316,532 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 12 111,246,508 - 111,311,923 (+) Ensembl panpan1.1 panPan2
Atp2a2 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405118 156,121,831 - 156,178,459 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936558 3,300,941 - 3,357,941 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936558 3,300,941 - 3,357,595 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
ATP2A2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 14 31,674,757 - 31,744,969 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 14 31,674,659 - 31,744,981 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 14 33,446,619 - 33,491,489 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Sscrofa10.2 14 33,642,897 - 33,670,781 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
ATP2A2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 11 105,522,175 - 105,590,291 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 11 105,522,157 - 105,590,958 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666037 139,532,362 - 139,600,791 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Atp2a2
.
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
6
5
5
23
22
16
6
6
6
6
33
22
12
14
10
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSCAFT00000027396 ⟹ ENSCAFP00000025477
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,566 - 8,209,388 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000061158 ⟹ ENSCAFP00000065195
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,236 - 8,205,995 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000061176 ⟹ ENSCAFP00000060744
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,236 - 8,205,033 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000062670 ⟹ ENSCAFP00000049691
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,236 - 8,205,033 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000065981 ⟹ ENSCAFP00000050835
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,236 - 8,207,683 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000072784 ⟹ ENSCAFP00000046584
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,236 - 8,205,851 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000074967 ⟹ ENSCAFP00000065186
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,236 - 8,205,033 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000081049 ⟹ ENSCAFP00000059945
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,653 - 8,209,388 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000081324 ⟹ ENSCAFP00000046784
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 26 8,148,566 - 8,209,388 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00845048728 ⟹ ENSCAFP00845038231
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl 26 8,406,107 - 8,463,938 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00845048846 ⟹ ENSCAFP00845038321
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl 26 8,406,108 - 8,467,504 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00845048913 ⟹ ENSCAFP00845038370
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl 26 8,406,108 - 8,464,108 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00845048985 ⟹ ENSCAFP00845038427
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl 26 8,406,108 - 8,463,964 (+) Ensembl
RefSeq Acc Id:
NM_001003214 ⟹ NP_001003214
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 26 8,148,566 - 8,209,392 (+) NCBI Dog10K_Boxer_Tasha 26 8,312,735 - 8,373,567 (+) NCBI ROS_Cfam_1.0 26 8,406,466 - 8,467,508 (+) NCBI UMICH_Zoey_3.1 26 8,366,182 - 8,427,199 (+) NCBI UNSW_CanFamBas_1.0 26 8,424,775 - 8,485,590 (+) NCBI UU_Cfam_GSD_1.0 26 8,381,368 - 8,442,436 (+) NCBI
Sequence:
GAATTCCGTCTGGGGGAGGGGGCGCGGGGTGATTCAGCGCCCGGCGAGGCGGAAGCGGCCGCAGGAGGAGGAGGAGGAGGAGGAGGGGGAGAGGCCTGTCCGCGCCTGGGCGCCCGGGGTGGCACGAG
hide sequence
RefSeq Acc Id:
XR_005302127
Type:
NON-CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 26 8,406,525 - 8,467,508 (+) NCBI
RefSeq Acc Id:
NP_001003214 ⟸ NM_001003214
- UniProtKB:
O46674 (UniProtKB/Swiss-Prot), B6CAN1 (UniProtKB/TrEMBL), A0A8C0KWJ6 (UniProtKB/TrEMBL), A0A8C0T8C6 (UniProtKB/TrEMBL)
- Sequence:
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK
hide sequence
Ensembl Acc Id:
ENSCAFP00000065186 ⟸ ENSCAFT00000074967
Ensembl Acc Id:
ENSCAFP00000025477 ⟸ ENSCAFT00000027396
Ensembl Acc Id:
ENSCAFP00000049691 ⟸ ENSCAFT00000062670
Ensembl Acc Id:
ENSCAFP00000046584 ⟸ ENSCAFT00000072784
Ensembl Acc Id:
ENSCAFP00000050835 ⟸ ENSCAFT00000065981
Ensembl Acc Id:
ENSCAFP00000065195 ⟸ ENSCAFT00000061158
Ensembl Acc Id:
ENSCAFP00000060744 ⟸ ENSCAFT00000061176
Ensembl Acc Id:
ENSCAFP00000046784 ⟸ ENSCAFT00000081324
Ensembl Acc Id:
ENSCAFP00000059945 ⟸ ENSCAFT00000081049
Ensembl Acc Id:
ENSCAFP00845038370 ⟸ ENSCAFT00845048913
Ensembl Acc Id:
ENSCAFP00845038427 ⟸ ENSCAFT00845048985
Ensembl Acc Id:
ENSCAFP00845038321 ⟸ ENSCAFT00845048846
Ensembl Acc Id:
ENSCAFP00845038231 ⟸ ENSCAFT00845048728
RGD ID: 13687892 Promoter ID: EPDNEW_C5962 Type: initiation region Name: ATP2A2_1 Description: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Dog Assembly Chr Position (strand) Source CanFam3.1 26 8,148,656 - 8,148,716 EPDNEW
