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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:glycerophospholipid metabolic pathway
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Accession:PW:0000354 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of glycerophospholipids, also known as phospholipids. They are key components of membranes and some are also involved in signaling.
Synonyms:related_synonym: glycerophospholipid metabolic process;   phospholipid metabolic pathway


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glycerophospholipid metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) ISO SMPDB SMP:00025 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184 		JBrowse link
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 ISO SMPDB SMP:00025 NCBI chr 6:31,815,586...31,823,526
Ensembl chr 6:32,695,475...32,704,432 		JBrowse link
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase ISO SMPDB SMP:00025 Ensembl chr16:30,227,772...30,233,145 JBrowse link
G CDS1 CDP-diacylglycerol synthase 1 ISO SMPDB SMP:00025 NCBI chr 4:39,530,229...39,598,543
Ensembl chr 4:45,379,856...45,448,170 		JBrowse link
G CHAT choline O-acetyltransferase ISO SMPDB SMP:00025 NCBI chr10:44,574,925...44,629,618 JBrowse link
G CHKA choline kinase alpha ISO SMPDB SMP:00025 NCBI chr11:63,134,776...63,202,516
Ensembl chr11:66,444,406...66,510,221 		JBrowse link
G CHPT1 choline phosphotransferase 1 ISO SMPDB SMP:00025 NCBI chr12:99,278,842...99,311,790
Ensembl chr12:102,692,554...102,711,745 		JBrowse link
G CRLS1 cardiolipin synthase 1 ISO SMPDB SMP:00025 NCBI chr20:6,003,915...6,037,853
Ensembl chr20:5,786,880...5,820,285 		JBrowse link
G DGKA diacylglycerol kinase alpha ISO SMPDB SMP:00025 NCBI chr12:32,958,287...32,981,164
Ensembl chr12:33,207,947...33,701,912 		JBrowse link
G GDE1 glycerophosphodiester phosphodiesterase 1 ISO SMPDB SMP:00025 NCBI chr16:18,789,681...18,809,783
Ensembl chr16:19,602,611...19,623,041 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial ISO SMPDB SMP:00025 NCBI chr10:108,747,370...108,781,270
Ensembl chr10:112,186,744...112,246,549 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 ISO SMPDB SMP:00025 NCBI chr12:38,644,466...38,651,924
Ensembl chr12:39,541,550...39,549,040 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 ISO SMPDB SMP:00025 NCBI chr2B:43,694,744...43,845,764
Ensembl chr2B:160,938,514...161,117,320 		JBrowse link
G LYPLA1 lysophospholipase 1 ISO SMPDB SMP:00025 NCBI chr 8:50,474,238...50,529,167
Ensembl chr 8:47,850,592...47,905,367 		JBrowse link
G PCYT1A phosphate cytidylyltransferase 1A, choline ISO SMPDB SMP:00025 NCBI chr 3:193,574,603...193,633,601
Ensembl chr 3:203,517,951...203,576,854 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO SMPDB SMP:00025 NCBI chr17:33,703,800...33,790,470
Ensembl chr17:38,651,024...38,737,202 		JBrowse link
G PGS1 phosphatidylglycerophosphate synthase 1 ISO SMPDB SMP:00025 NCBI chr17:72,455,008...72,501,058
Ensembl chr17:78,003,519...78,049,331 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 ISO SMPDB SMP:00025 NCBI chr17:8,373,032...8,381,410
Ensembl chr17:8,357,513...8,364,416 		JBrowse link
G PISD phosphatidylserine decarboxylase ISO SMPDB SMP:00025 NCBI chr22:12,638,418...12,682,733
Ensembl chr22:30,495,546...30,539,389 		JBrowse link
G PLA2G15 phospholipase A2 group XV ISO SMPDB SMP:00025 NCBI chr16:48,612,240...48,635,721
Ensembl chr16:68,006,105...68,030,812 		JBrowse link
G PLA2G2D phospholipase A2 group IID ISO SMPDB SMP:00025 NCBI chr 1:19,066,890...19,074,711
Ensembl chr 1:20,110,323...20,117,618 		JBrowse link
G PLD2 phospholipase D2 ISO SMPDB SMP:00025 NCBI chr17:4,853,919...4,870,254
Ensembl chr17:4,843,217...4,858,425 		JBrowse link
G PLPP1 phospholipid phosphatase 1 ISO SMPDB SMP:00025 NCBI chr 5:58,495,348...58,605,309
Ensembl chr 5:60,160,274...60,227,806 		JBrowse link
G PTDSS1 phosphatidylserine synthase 1 ISO SMPDB SMP:00025 NCBI chr 8:92,886,918...92,959,611
Ensembl chr 8:95,084,103...95,156,104 		JBrowse link
G PTDSS2 phosphatidylserine synthase 2 ISO SMPDB SMP:00025 NCBI chr11:448,061...492,470
Ensembl chr11:486,021...526,469 		JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 ISO SMPDB SMP:00025 NCBI chr11:47,515,304...47,521,529
Ensembl chr11:48,064,931...48,073,474 		JBrowse link
cardiolipin biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRLS1 cardiolipin synthase 1 ISO RGD PMID:24769127 RGD:10400850 NCBI chr20:6,003,915...6,037,853
Ensembl chr20:5,786,880...5,820,285 		JBrowse link
G PGS1 phosphatidylglycerophosphate synthase 1 ISO RGD PMID:24769127 RGD:10400850 NCBI chr17:72,455,008...72,501,058
Ensembl chr17:78,003,519...78,049,331 		JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 ISO RGD PMID:24769127 RGD:10400850 NCBI chr11:47,515,304...47,521,529
Ensembl chr11:48,064,931...48,073,474 		JBrowse link
G TAMM41 TAM41 mitochondrial translocator assembly and maintenance homolog ISO RGD PMID:24769127 RGD:10400850 NCBI chr 3:11,655,271...11,780,497
Ensembl chr 3:12,068,067...12,124,535 		JBrowse link
cardiolipin metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100986481 cytochrome c ISO RGD PMID:24769127 RGD:10400850 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549 		JBrowse link
G LOC100991599 creatine kinase U-type, mitochondrial ISO RGD PMID:24769127 RGD:10400850 NCBI chr15:22,654,349...22,660,890 JBrowse link
G NME4 NME/NM23 nucleoside diphosphate kinase 4 ISO RGD PMID:24769127 RGD:10400850 Ensembl chr16:389,068...393,976 JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:24769127 RGD:10400850 NCBI chr  X:143,853,054...143,863,491
Ensembl chr  X:153,725,294...153,734,046 		JBrowse link
phosphoinositide metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 ISO SMPDB SMP:00463 NCBI chr11:46,355,026...46,556,091
Ensembl chr11:46,905,454...47,103,205 		JBrowse link
G BECN1 beclin 1 ISO SMPDB SMP:00463 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase ISO SMPDB SMP:00463 Ensembl chr16:30,227,772...30,233,145 JBrowse link
G EGFR epidermal growth factor receptor ISO SMPDB SMP:00463 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO SMPDB SMP:00463 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G FIG4 FIG4 phosphoinositide 5-phosphatase ISO SMPDB SMP:00463 NCBI chr 6:107,495,637...107,631,201
Ensembl chr 6:111,539,937...111,673,894 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO SMPDB SMP:00463 NCBI chr 4:134,405,934...135,213,851
Ensembl chr 4:145,706,307...146,141,029 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D ISO SMPDB SMP:00463 NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190 		JBrowse link
G INPP5E inositol polyphosphate-5-phosphatase E ISO SMPDB SMP:00463 NCBI chr 9:107,502,838...107,516,325
Ensembl chr 9:136,483,144...136,492,731 		JBrowse link
G PI4KA phosphatidylinositol 4-kinase alpha ISO SMPDB SMP:00463 NCBI chr22:2,931,523...3,082,475 JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha ISO SMPDB SMP:00463 NCBI chr11:17,143,024...17,263,920
Ensembl chr11:16,828,966...16,949,856 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 ISO SMPDB SMP:00463 NCBI chr18:35,203,896...35,336,512
Ensembl chr18:38,754,789...38,882,037 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO SMPDB SMP:00463 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO SMPDB SMP:00463 NCBI chr 1:8,418,570...8,495,435
Ensembl chr 1:9,686,208...9,724,633 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO SMPDB SMP:00463 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960 		JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 ISO SMPDB SMP:00463 NCBI chr 3:127,743,873...127,834,512
Ensembl chr 3:135,089,584...135,157,193 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing ISO SMPDB SMP:00463 NCBI chr2B:95,505,376...95,597,792
Ensembl chr2B:213,628,997...213,721,299 		JBrowse link
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO SMPDB SMP:00463 NCBI chr10:22,691,355...22,870,628 JBrowse link
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha ISO SMPDB SMP:00463 NCBI chr 1:126,547,793...126,598,618
Ensembl chr 1:130,195,974...130,246,198 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO SMPDB SMP:00463 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G PTEN phosphatase and tensin homolog ISO SMPDB SMP:00463 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G SYNJ1 synaptojanin 1 ISO SMPDB SMP:00463 NCBI chr21:18,990,526...19,088,839
Ensembl chr21:32,368,949...32,466,994 		JBrowse link
G VAC14 VAC14 component of PIKFYVE complex ISO SMPDB SMP:00463 NCBI chr16:54,216,303...54,330,073
Ensembl chr16:70,520,440...70,634,143 		JBrowse link
plasmalogen biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 ISO SMPDB SMP:00479 NCBI chr 6:31,815,586...31,823,526
Ensembl chr 6:32,695,475...32,704,432 		JBrowse link
G AGPS alkylglycerone phosphate synthase ISO SMPDB SMP:00479 NCBI chr2B:64,671,136...64,823,956
Ensembl chr2B:182,375,149...182,520,557 		JBrowse link
G CEPT1 choline/ethanolamine phosphotransferase 1 ISO SMPDB SMP:00479 NCBI chr 1:113,785,264...113,830,648
Ensembl chr 1:126,514,879...126,561,850 		JBrowse link
G GNPAT glyceronephosphate O-acyltransferase ISO SMPDB SMP:00479 NCBI chr 1:206,794,245...206,830,840
Ensembl chr 1:211,819,259...211,855,885 		JBrowse link
G PLPP1 phospholipid phosphatase 1 ISO SMPDB SMP:00479 NCBI chr 5:58,495,348...58,605,309
Ensembl chr 5:60,160,274...60,227,806 		JBrowse link
plasmalogen metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 ISO SMPDB SMP:00479 NCBI chr 6:31,815,586...31,823,526
Ensembl chr 6:32,695,475...32,704,432 		JBrowse link
G AGPS alkylglycerone phosphate synthase ISO SMPDB SMP:00479 NCBI chr2B:64,671,136...64,823,956
Ensembl chr2B:182,375,149...182,520,557 		JBrowse link
G CEPT1 choline/ethanolamine phosphotransferase 1 ISO SMPDB SMP:00479 NCBI chr 1:113,785,264...113,830,648
Ensembl chr 1:126,514,879...126,561,850 		JBrowse link
G GNPAT glyceronephosphate O-acyltransferase ISO SMPDB SMP:00479 NCBI chr 1:206,794,245...206,830,840
Ensembl chr 1:211,819,259...211,855,885 		JBrowse link
G PLPP1 phospholipid phosphatase 1 ISO SMPDB SMP:00479 NCBI chr 5:58,495,348...58,605,309
Ensembl chr 5:60,160,274...60,227,806 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4063
    classic metabolic pathway 1016
      lipid metabolic pathway 260
        glycerophospholipid metabolic pathway 56
          altered glycerophospholipid metabolic pathway + 0
          glycerophospholipid degradation pathway 0
          phosphatidylcholine metabolic pathway + 0
          phosphatidylglycerol metabolic pathway + 8
          phosphatidylinositol metabolic pathway + 23
          phosphatidylserine metabolic pathway 0
          plasmalogen metabolic pathway + 5
paths to the root