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ONTOLOGY REPORT - ANNOTATIONS


Term:glycerophospholipid metabolic pathway
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Accession:PW:0000354 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of glycerophospholipids, also known as phospholipids. They are key components of membranes and some are also involved in signaling.
Synonyms:related_synonym: KEGG:00564;   SMP:00025;   phospholipid metabolic pathway


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glycerophospholipid metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 7 92,915,065 92,922,079 RGD:9068941
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 JBrowse link 6 31,815,586 31,823,526 RGD:9068941
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase RGD:9068941
G CDS1 CDP-diacylglycerol synthase 1 JBrowse link 4 39,530,229 39,598,543 RGD:9068941
G CHAT choline O-acetyltransferase JBrowse link 10 44,574,925 44,629,618 RGD:9068941
G CHKA choline kinase alpha JBrowse link 11 63,134,776 63,202,516 RGD:9068941
G CHPT1 choline phosphotransferase 1 JBrowse link 12 99,278,842 99,311,790 RGD:9068941
G CRLS1 cardiolipin synthase 1 JBrowse link 20 6,003,915 6,037,853 RGD:9068941
G DGKA diacylglycerol kinase alpha JBrowse link 12 32,958,287 32,981,164 RGD:9068941
G GDE1 glycerophosphodiester phosphodiesterase 1 JBrowse link 16 18,789,681 18,809,783 RGD:9068941
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 10 108,747,370 108,781,270 RGD:9068941
G GPD1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 12 38,644,466 38,651,924 RGD:9068941
G GPD2 glycerol-3-phosphate dehydrogenase 2 JBrowse link 2B 43,694,744 43,845,764 RGD:9068941
G LYPLA1 lysophospholipase 1 JBrowse link 8 50,474,238 50,529,167 RGD:9068941
G PCYT1A phosphate cytidylyltransferase 1, choline, alpha JBrowse link 3 193,574,603 193,633,601 RGD:9068941
G PEMT phosphatidylethanolamine N-methyltransferase JBrowse link 17 33,703,800 33,790,470 RGD:9068941
G PGS1 phosphatidylglycerophosphate synthase 1 JBrowse link 17 72,455,008 72,501,058 RGD:9068941
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 JBrowse link 17 8,373,032 8,381,410 RGD:9068941
G PISD phosphatidylserine decarboxylase JBrowse link 22 12,638,418 12,682,733 RGD:9068941
G PLA2G15 phospholipase A2 group XV JBrowse link 16 48,612,240 48,635,721 RGD:9068941
G PLA2G2D phospholipase A2 group IID JBrowse link 1 19,066,890 19,074,711 RGD:9068941
G PLD2 phospholipase D2 JBrowse link 17 4,853,919 4,870,254 RGD:9068941
G PLPP1 phospholipid phosphatase 1 JBrowse link 5 58,495,348 58,605,309 RGD:9068941
G PTDSS1 phosphatidylserine synthase 1 JBrowse link 8 92,886,918 92,959,611 RGD:9068941
G PTDSS2 phosphatidylserine synthase 2 JBrowse link 11 448,061 492,470 RGD:9068941
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 JBrowse link 11 47,515,304 47,521,529 RGD:9068941
phosphoinositide metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMBRA1 autophagy and beclin 1 regulator 1 JBrowse link 11 46,355,026 46,556,091 RGD:9068941
G BECN1 beclin 1 JBrowse link 17 14,493,619 14,507,809 RGD:9068941
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 7 55,614,042 55,807,285 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 17,560,337 17,600,808 RGD:9068941
G FIG4 FIG4 phosphoinositide 5-phosphatase JBrowse link 6 107,495,637 107,631,201 RGD:9068941
G INPP4B inositol polyphosphate-4-phosphatase type II B JBrowse link 4 134,405,934 135,213,851 RGD:9068941
G INPP5D inositol polyphosphate-5-phosphatase D JBrowse link 2B 120,287,606 120,436,526 RGD:9068941
G INPP5E inositol polyphosphate-5-phosphatase E JBrowse link 9 107,502,838 107,516,325 RGD:9068941
G PI4KA phosphatidylinositol 4-kinase alpha JBrowse link 22 2,931,523 3,082,475 RGD:9068941
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha JBrowse link 11 17,143,024 17,263,920 RGD:9068941
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 JBrowse link 18 35,203,896 35,336,512 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 176,182,765 176,272,024 RGD:9068941
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 1 8,418,570 8,495,435 RGD:9068941
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 45,701,219 45,786,652 RGD:9068941
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 JBrowse link 3 127,743,873 127,834,512 RGD:9068941
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing JBrowse link 2B 95,505,376 95,597,792 RGD:9068941
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha JBrowse link 10 22,691,355 22,870,628 RGD:9068941
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha JBrowse link 1 126,547,793 126,598,618 RGD:9068941
G PLCB1 phospholipase C beta 1 JBrowse link 20 8,106,665 8,858,572 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 84,587,841 84,689,043 RGD:9068941
G SYNJ1 synaptojanin 1 JBrowse link 21 18,990,526 19,088,839 RGD:9068941
G VAC14 VAC14 component of PIKFYVE complex JBrowse link 16 54,216,303 54,330,073 RGD:9068941
plasmalogen biosynthetic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 JBrowse link 6 31,815,586 31,823,526 RGD:9068941
G AGPS alkylglycerone phosphate synthase JBrowse link 2B 64,671,136 64,823,956 RGD:9068941
G CEPT1 choline/ethanolamine phosphotransferase 1 JBrowse link 1 113,785,264 113,830,648 RGD:9068941
G GNPAT glyceronephosphate O-acyltransferase JBrowse link 1 206,794,245 206,830,840 RGD:9068941
G PLPP1 phospholipid phosphatase 1 JBrowse link 5 58,495,348 58,605,309 RGD:9068941
plasmalogen metabolic pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 JBrowse link 6 31,815,586 31,823,526 RGD:9068941
G AGPS alkylglycerone phosphate synthase JBrowse link 2B 64,671,136 64,823,956 RGD:9068941
G CEPT1 choline/ethanolamine phosphotransferase 1 JBrowse link 1 113,785,264 113,830,648 RGD:9068941
G GNPAT glyceronephosphate O-acyltransferase JBrowse link 1 206,794,245 206,830,840 RGD:9068941
G PLPP1 phospholipid phosphatase 1 JBrowse link 5 58,495,348 58,605,309 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 2314
    classic metabolic pathway 723
      lipid metabolic pathway 197
        glycerophospholipid metabolic pathway 51
          altered glycerophospholipid metabolic pathway + 0
          phosphatidylcholine metabolic pathway + 0
          phosphatidylglycerol metabolic process + 0
          phosphatidylinositol metabolic pathway + 23
          phosphatidylserine metabolic process 0
          plasmalogen metabolic pathway + 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.