PCYT1A (phosphate cytidylyltransferase 1A, choline) - Rat Genome Database

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Gene: PCYT1A (phosphate cytidylyltransferase 1A, choline) Pan paniscus
Analyze
Symbol: PCYT1A
Name: phosphate cytidylyltransferase 1A, choline
RGD ID: 11858564
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); choline-phosphate cytidylyltransferase activity (ortholog); lipid binding (ortholog); INVOLVED IN phosphatidylcholine biosynthetic process (ortholog); PARTICIPATES IN glycerophospholipid metabolic pathway; lamivudine pharmacokinetics pathway; ASSOCIATED WITH autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); chromosome 3q29 microdeletion syndrome (ortholog); FOUND IN nuclear envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: choline-phosphate cytidylyltransferase A; phosphate cytidylyltransferase 1, choline, alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22194,098,897 - 194,161,227 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13194,103,614 - 194,166,603 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,574,603 - 193,633,601 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,522,292 - 203,576,851 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,517,951 - 203,576,854 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PCYT1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22194,098,897 - 194,161,227 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13194,103,614 - 194,166,603 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,574,603 - 193,633,601 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,522,292 - 203,576,851 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,517,951 - 203,576,854 (-)Ensemblpanpan1.1panPan2
PCYT1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383196,234,368 - 196,287,726 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3196,214,222 - 196,287,957 (-)EnsemblGRCh38hg38GRCh38
GRCh373195,961,239 - 196,014,597 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,449,650 - 197,498,981 (-)NCBINCBI36Build 36hg18NCBI36
Build 343197,453,567 - 197,502,894NCBI
Celera3194,546,889 - 194,595,863 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3193,264,968 - 193,311,721 (-)NCBIHuRef
CHM1_13195,936,083 - 195,985,409 (-)NCBICHM1_1
T2T-CHM13v2.03198,953,844 - 199,007,214 (-)NCBIT2T-CHM13v2.0
Pcyt1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,249,739 - 32,293,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,249,739 - 32,293,888 (+)EnsemblGRCm39 Ensembl
GRCm381632,430,921 - 32,475,065 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,430,921 - 32,475,070 (+)EnsemblGRCm38mm10GRCm38
MGSCv371632,431,007 - 32,475,151 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361632,350,743 - 32,391,762 (+)NCBIMGSCv36mm8
Celera1632,915,098 - 32,958,968 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1622.69NCBI
Pcyt1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,818,914 - 81,862,623 (-)NCBIGRCr8
mRatBN7.21168,313,860 - 68,357,828 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,313,882 - 68,357,357 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1177,154,021 - 77,194,395 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,818,577 - 69,859,107 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,843,143 - 68,883,509 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,547,865 - 71,592,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,548,222 - 71,591,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,632,576 - 74,676,227 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,133,325 - 70,173,686 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11170,190,913 - 70,212,531 (-)NCBI
Celera1167,749,599 - 67,789,957 (-)NCBICelera
Cytogenetic Map11q22NCBI
Pcyt1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,464,857 - 12,500,574 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542012,464,857 - 12,513,017 (-)NCBIChiLan1.0ChiLan1.0
PCYT1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13329,363,282 - 29,414,635 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3329,358,452 - 29,430,424 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3329,387,581 - 29,438,871 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03329,596,717 - 29,648,017 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3329,591,886 - 29,667,214 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13329,386,580 - 29,435,254 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03329,437,747 - 29,489,070 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03330,060,502 - 30,111,773 (-)NCBIUU_Cfam_GSD_1.0
Pcyt1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602124,946,958 - 125,000,520 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936784884,751 - 938,282 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936784884,751 - 938,901 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCYT1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13133,818,761 - 133,850,996 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113133,794,337 - 133,851,004 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213143,232,171 - 143,288,868 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PCYT1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11590,905,691 - 90,944,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604164,720,023 - 64,792,685 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pcyt1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,418,013 - 61,466,016 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473061,417,030 - 61,466,028 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000043571   ⟹   ENSPPAP00000020775
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3203,517,951 - 203,559,625 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000043574   ⟹   ENSPPAP00000020778
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3203,522,292 - 203,576,854 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000043582   ⟹   ENSPPAP00000020786
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3203,535,286 - 203,559,625 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000043586   ⟹   ENSPPAP00000020790
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3203,546,876 - 203,559,625 (-)Ensembl
RefSeq Acc Id: XM_003806420   ⟹   XP_003806468
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22194,098,897 - 194,161,223 (-)NCBI
NHGRI_mPanPan13194,103,614 - 194,166,603 (-)NCBI
Mhudiblu_PPA_v03193,574,603 - 193,633,600 (-)NCBI
PanPan1.13203,522,292 - 203,576,851 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953394   ⟹   XP_008951642
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22194,098,897 - 194,161,227 (-)NCBI
NHGRI_mPanPan13194,103,614 - 194,166,603 (-)NCBI
Mhudiblu_PPA_v03193,574,603 - 193,633,601 (-)NCBI
PanPan1.13203,522,292 - 203,576,612 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004670904
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22194,098,897 - 194,161,223 (-)NCBI
NHGRI_mPanPan13194,103,614 - 194,166,603 (-)NCBI
Mhudiblu_PPA_v03193,574,603 - 193,633,600 (-)NCBI
RefSeq Acc Id: XR_010111490
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22194,098,897 - 194,161,227 (-)NCBI
RefSeq Acc Id: XR_608804
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22194,098,897 - 194,161,223 (-)NCBI
NHGRI_mPanPan13194,103,614 - 194,166,603 (-)NCBI
Mhudiblu_PPA_v03193,574,603 - 193,633,600 (-)NCBI
PanPan1.13203,522,292 - 203,576,851 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003806468 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951642 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020775.1
  ENSPPAP00000020778
  ENSPPAP00000020778.1
  ENSPPAP00000020786.1
  ENSPPAP00000020790.1
Reference Protein Sequences
RefSeq Acc Id: XP_003806468   ⟸   XM_003806420
- UniProtKB: A0A2R9AU96 (UniProtKB/TrEMBL),   A0A2R9AY69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951642   ⟸   XM_008953394
- UniProtKB: A0A2R9AU96 (UniProtKB/TrEMBL),   A0A2R9AY69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000020775   ⟸   ENSPPAT00000043571
RefSeq Acc Id: ENSPPAP00000020778   ⟸   ENSPPAT00000043574
RefSeq Acc Id: ENSPPAP00000020786   ⟸   ENSPPAT00000043582
RefSeq Acc Id: ENSPPAP00000020790   ⟸   ENSPPAT00000043586
Protein Domains
Cytidyltransferase-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033606 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043571.1 UniProtKB/TrEMBL
  ENSPPAT00000043574.1 UniProtKB/TrEMBL
  ENSPPAT00000043582.1 UniProtKB/TrEMBL
  ENSPPAT00000043586.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
InterPro CCT UniProtKB/TrEMBL
  Cyt_trans-like UniProtKB/TrEMBL
  Pcy1-like UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
KEGG Report pps:100990415 UniProtKB/TrEMBL
NCBI Gene PCYT1A ENTREZGENE
PANTHER CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A UniProtKB/TrEMBL
  PTHR10739 UniProtKB/TrEMBL
Pfam CTP_transf_like UniProtKB/TrEMBL
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
UniProt A0A2R9ATY7_PANPA UniProtKB/TrEMBL
  A0A2R9AU96 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AY69 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AY84_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-10 PCYT1A  phosphate cytidylyltransferase 1A, choline  PCYT1A  phosphate cytidylyltransferase 1, choline, alpha  Symbol and/or name change 5135510 APPROVED