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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal male reproductive system physiology
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Accession:MP:0003698 term browser browse the term
Definition:any functional anomaly of the male organs associated with producing offspring


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decreased sperm progressive motility term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Defb23em2MlitDefb26em2Mlit defensin beta 23, defensin beta 26; CRISPR/Cas9 induced mutant2, Mlit IMP RGD PMID:29141997 RGD:13782190
impaired acrosome reaction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acr acrosin IMP RGD PMID:28859281 RGD:13464336 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474 		JBrowse link
increased male germ cell apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 IMP RGD PMID:28834365 RGD:14995504 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Wwox WW domain-containing oxidoreductase IAGP compared to wild type and heterozygotes RGD PMID:18676360 RGD:150429974 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
G Wwoxlde WW domain-containing oxidoreductase; lde mutant IAGP compared to wild type and heterozygotes RGD PMID:18676360 RGD:150429974
male infertility term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sbf1 SET binding factor 1 IAGP DNA:substitution:intron 37:G>A (rat) RGD PMID:27335132 RGD:38549340 NCBI chr 7:120,358,338...120,385,022
Ensembl chr 7:120,358,338...120,384,902 		JBrowse link
G Sbf1m1Ipcv SET binding factor 1; mutation 1, Institute of Physiology, Czechoslovac Academy of Sciences IAGP RGD PMID:27335132 RGD:38549340
premature acrosome reaction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Defb23em2MlitDefb26em2Mlit defensin beta 23, defensin beta 26; CRISPR/Cas9 induced mutant2, Mlit IMP RGD PMID:29141997 RGD:13782190
reduced male fertility term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdk branched chain ketoacid dehydrogenase kinase IAGP DNA:missense mutation:cds:G369E (rat) RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Nkx3-1 NK3 homeobox 1 IMP compared to wild type RGD PMID:33368416 RGD:150573817 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nkx3-1em1Pjhak NK3 homeobox 1; TALEN induced mutant 1, Pjhak IMP compared to wild type RGD PMID:33368416 RGD:150573817
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    reproductive system phenotype 129
      abnormal reproductive system physiology 64
        abnormal male reproductive system physiology 25
          abnormal bulbourethral gland physiology 0
          abnormal ejaculation + 0
          abnormal epididymis physiology + 0
          abnormal male germ cell physiology + 4
          abnormal penile erection + 0
          abnormal prostate gland physiology + 4
          abnormal seminal vesicle physiology + 0
          abnormal sperm physiology + 5
          abnormal testis physiology + 1
          male infertility 5
          penis inflammation 0
          reduced male fertility 6
paths to the root