Nkx3-1<sup>em1Pjhak</sup> (NK3 homeobox 1; TALEN induced mutant 1, Pjhak) - Rat Genome Database

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Gene: Nkx3-1em1Pjhak (NK3 homeobox 1; TALEN induced mutant 1, Pjhak) Rattus norvegicus
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Symbol: Nkx3-1em1Pjhak
Name: NK3 homeobox 1; TALEN induced mutant 1, Pjhak
RGD ID: 150573819
Description: A pair of TALENs targeting coding region of rat Nkx3-1gene was electroporated into SD zygotes to create NKx3-1 mutants. The resulting mutation was indel mutation with sequences loss beyond TALEN recognition resulting a premature termination codon of the protein.
ASSOCIATED WITH abnormal copulatory plug deposition; decreased litter size; decreased prostate gland weight
Type: allele  of Nkx3-1  
Previously known as: Nkx3-1^[em1Pjhak]
Is Marker For: Strains:   SD-Nkx3-1em1Pjhak-/-   SD-Nkx3-1em1Pjhak+/-  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. TALEN-mediated generation of Nkx3.1 knockout rat model. Lee JM, etal., Prostate. 2021 Feb;81(3):182-193. doi: 10.1002/pros.24095. Epub 2020 Dec 28.

Genomics


Related Rat Strains
The following Strains have been annotated to Nkx3-1em1Pjhak
SD-Nkx3-1em1Pjhak+/-     SD-Nkx3-1em1Pjhak-/-    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information