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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:embryonic lethality
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Accession:MP:0008762 term browser browse the term
Definition:death of an animal within the embryonic period prior to organogenesis (Mus: prior to E14)
Comment:Note that a term with the former name embryonic lethality exists as MP:0002080. In many species, the terms prenatal lethality and embryonic lethality are used interchangeably. However, this is not technically correct and we have modified this ontology to define the prenatal period to include the embryonic stages distinctly from the fetal stages. The names embryonic lethality and embryonic death have been retained as a narrow synonyms for the prenatal lethality term to aid in searching for those species that may use these terms as synonyms.
Synonyms:exact_synonym: embryonic death


show annotations for term's descendants           Sort by:
embryonic lethality term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit IMP RGD PMID:26873552 RGD:11573213 NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794 		JBrowse link
G Fh fumarate hydratase IMP RGD PMID:27556703 RGD:13792708 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fhem1 fumarate hydratase; TALEN induced mutant 1 IMP RGD PMID:27556703 RGD:13792708
G Flcn folliculin treatment IMP RGD PMID:16369488 RGD:13605606 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:25088526 RGD:11568651 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
embryonic lethality, complete penetrance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Isca1 iron-sulfur cluster assembly 1 IMP RGD PMID:31016283 RGD:39131292 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955 		JBrowse link
embryonic lethality, incomplete penetrance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb16 zinc finger and BTB domain containing 16 IAGP RGD PMID:27727328 RGD:40924666 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5403
    mortality/aging 157
      abnormal survival 119
        preweaning lethality 19
          prenatal lethality 8
            embryonic lethality 7
              embryonic lethality during organogenesis + 0
              embryonic lethality prior to tooth bud stage + 0
              embryonic lethality, complete penetrance 1
              embryonic lethality, incomplete penetrance 1
paths to the root