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ONTOLOGY REPORT - ANNOTATIONS

Term:multi-pass transmembrane protein insertion into ER membrane
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Accession:GO:0160063 term browser browse the term
Definition:A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions.


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multi-pass transmembrane protein insertion into ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC47 coiled-coil domain containing 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,165,268...15,186,141
Ensembl chr12:15,165,405...15,192,356 		JBrowse link
G LOC100626015 nodal modulator 1 involved_in ISO (PMID:36261522) UniProt PMID:36261522 NCBI chr 3:28,197,027...28,258,061 JBrowse link
G NCLN nicalin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,369,926...75,390,609
Ensembl chr 2:75,369,955...75,390,545 		JBrowse link
G RAB5IF RAB5 interacting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:39,868,849...39,878,623
Ensembl chr17:39,868,882...39,882,690 		JBrowse link
G TMCO1 transmembrane and coiled-coil domains 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:84,961,912...85,011,139
Ensembl chr 4:84,961,819...85,017,820 		JBrowse link
G TMEM147 transmembrane protein 147 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,979,195...44,981,051
Ensembl chr 6:44,979,190...44,981,049 		JBrowse link
G WDR83OS WD repeat domain 83 opposite strand involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:66,312,920...66,328,000
Ensembl chr 2:66,325,992...66,328,004 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    cellular process 16838
      cellular component organization or biogenesis 6723
        cellular component organization 6509
          organelle organization 3633
            endoplasmic reticulum organization 101
              protein insertion into ER membrane 30
                multi-pass transmembrane protein insertion into ER membrane 7
Path 2
Term Annotations click to browse term
  biological_process 17799
    localization 5399
      cellular localization 3552
        cellular macromolecule localization 2589
          protein localization 2577
            protein localization to membrane 669
              establishment of protein localization to membrane 284
                protein insertion into membrane 48
                  protein insertion into ER membrane 30
                    multi-pass transmembrane protein insertion into ER membrane 7
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