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Ontology Browser

Term:
multi-pass transmembrane protein insertion into ER membrane (GO:0160063)
Annotations: Rat: (7) Mouse: (7) Human: (9) Chinchilla: (6) Bonobo: (6) Dog: (7) Squirrel: (6) Pig: (7) Naked Mole-rat: (6) Green Monkey: (6)
Parent Terms Term With Siblings Child Terms
multi-pass transmembrane protein insertion into ER membrane  
A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions.
protein insertion into ER membrane by internal uncleaved signal-anchor sequence 
protein insertion into ER membrane by N-terminal cleaved signal sequence 
protein insertion into ER membrane by stop-transfer membrane-anchor sequence  
tail-anchored membrane protein insertion into ER membrane  

Synonyms
Definition Sources: PMID:36261522, PMID:36261528

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