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ONTOLOGY REPORT - ANNOTATIONS

Term:multi-pass transmembrane protein insertion into ER membrane
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Accession:GO:0160063 term browser browse the term
Definition:A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions.


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multi-pass transmembrane protein insertion into ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC47 coiled-coil domain containing 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:57,825,328...57,853,626
Ensembl chr17:62,970,109...62,998,465 		JBrowse link
G NCLN nicalin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,211,474...2,235,691
Ensembl chr19:3,166,042...3,189,681 		JBrowse link
G RAB5IF RAB5 interacting factor involved_in ISO (PMID:36261528)
(PMID:36261522)		 UniProt PMID:36261522 PMID:36261528 NCBI chr20:32,938,953...32,945,648
Ensembl chr20:34,059,109...34,065,624 		JBrowse link
G TMCO1 transmembrane and coiled-coil domains 1 involved_in ISO (PMID:36261522)
(PMID:36261528)		 UniProt PMID:36261522 PMID:36261528 NCBI chr 1:141,159,657...141,201,018
Ensembl chr 1:144,944,105...144,989,794 		JBrowse link
G TMEM147 transmembrane protein 147 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,492,030...32,493,944
Ensembl chr19:41,229,033...41,230,960 		JBrowse link
G WDR83OS WD repeat domain 83 opposite strand involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,230,204...12,231,881
Ensembl chr19:12,975,314...12,976,896 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cellular component organization or biogenesis 6620
        cellular component organization 6401
          organelle organization 3612
            endoplasmic reticulum organization 96
              protein insertion into ER membrane 28
                multi-pass transmembrane protein insertion into ER membrane 6
Path 2
Term Annotations click to browse term
  biological_process 16440
    localization 5279
      cellular localization 3501
        cellular macromolecule localization 2540
          protein localization 2528
            protein localization to membrane 668
              establishment of protein localization to membrane 274
                protein insertion into membrane 45
                  protein insertion into ER membrane 28
                    multi-pass transmembrane protein insertion into ER membrane 6
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