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ONTOLOGY REPORT - ANNOTATIONS


Term:histone decrotonylase activity
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Accession:GO:0160009 term browser browse the term
Definition:Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] = (2E)-2-butenoate + L-lysyl-[histone].



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histone decrotonylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC1 histone deacetylase 1 enables IDA
IEA
(PMID:28497810) UniProt
Ensembl
PMID:28497810 GO_REF:0000107 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HDAC2 histone deacetylase 2 enables IDA (PMID:28497810) UniProt PMID:28497810 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDAC3 histone deacetylase 3 enables IDA
IEA
(PMID:28497810) UniProt
Ensembl
PMID:28497810 GO_REF:0000107 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849
JBrowse link
G HDAC8 histone deacetylase 8 enables IDA (PMID:28497810) UniProt PMID:28497810 NCBI chr  X:72,329,516...72,572,843
Ensembl chr  X:72,329,516...72,573,101
JBrowse link
NAD-dependent histone decrotonylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT1 sirtuin 1 enables IDA (PMID:28497810) UniProt PMID:28497810 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19566
    catalytic activity 5977
      catalytic activity, acting on a protein 2452
        histone modifying activity 230
          histone decrotonylase activity 5
            NAD-dependent histone decrotonylase activity + 1
Path 2
Term Annotations click to browse term
  molecular_function 19566
    catalytic activity 5977
      hydrolase activity 2627
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 147
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 80
            protein decrotonylase activity 5
              histone decrotonylase activity 5
                NAD-dependent histone decrotonylase activity + 1
paths to the root