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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:Norrin signaling pathway
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Accession:GO:0110135 term browser browse the term
Definition:The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.


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Norrin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd4 frizzled class receptor 4 involved_in IDA
ISO		 (MGI:3621833|PMID:15035989) BHF-UCL
MGI		 PMID:15035989 GO_REF:0000119 MGI:3621833 MGI:4834177 NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342 		JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 involved_in IDA (MGI:3621833|PMID:15035989) BHF-UCL PMID:15035989 MGI:3621833 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564 		JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 involved_in IDA (MGI:3621833|PMID:15035989) BHF-UCL PMID:15035989 MGI:3621833 NCBI chr 6:134,423,439...134,543,876
Ensembl chr 6:134,423,439...134,543,928 		JBrowse link
G Ndp Norrie disease (pseudoglioma) (human) involved_in IDA
ISO
IBA		 (MGI:3621833|PMID:15035989) BHF-UCL
MGI
GO_Central		 PMID:15035989 GO_REF:0000033 GO_REF:0000119 MGI:3621833 MGI:4834177 NCBI chr  X:16,751,760...16,778,013
Ensembl chr  X:16,751,760...16,778,013 		JBrowse link
G Tspan12 tetraspanin 12 acts_upstream_of_or_within IMP (PMID:30478038) MGI PMID:30478038 NCBI chr 6:21,771,390...21,879,557
Ensembl chr 6:21,771,394...21,852,514 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17546
      signal transduction 6676
        cell surface receptor signaling pathway 2922
          Norrin signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13127
      regulation of biological process 12732
        signaling 7290
          signal transduction 6676
            cell surface receptor signaling pathway 2922
              Norrin signaling pathway 5
paths to the root