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ONTOLOGY REPORT - ANNOTATIONS

Term:K63-linked polyubiquitin modification-dependent protein binding
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Accession:GO:0070530 term browser browse the term
Definition:Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.


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K63-linked polyubiquitin modification-dependent protein binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCC2 activating signal cointegrator 1 complex subunit 2 enables IDA (PMID:36302773) UniProt PMID:36302773 NCBI chr22:29,788,611...29,838,274
Ensembl chr22:29,788,609...29,838,304 		JBrowse link
G ATRIP ATR interacting protein enables IDA (PMID:24332808) UniProt PMID:24332808 NCBI chr 3:48,446,737...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G FAAP20 FA core complex associated protein 20 enables IDA
IBA		 (PMID:22343915), (PMID:22705371) UniProt
GO_Central		 PMID:22343915 PMID:22705371 GO_REF:0000033 NCBI chr 1:2,184,477...2,212,720
Ensembl chr 1:2,184,461...2,212,720 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon NOT|enables IMP (PMID:24882218) UniProt PMID:24882218 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma enables IEA
IBA
IDA		 (PMID:18287044) InterPro
GO_Central
UniProt		 PMID:18287044 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G MINDY2 MINDY lysine 48 deubiquitinase 2 enables IDA (PMID:28082312) UniProt PMID:28082312 NCBI chr15:58,771,302...58,861,900
Ensembl chr15:58,771,192...58,861,900 		JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor contributes_to
enables		 ISO
IEA		 PMID:12847084 ParkinsonsUK-UCL
Ensembl		 PMID:12847084 GO_REF:0000107 RGD:10047330 NCBI chr17:81,556,885...81,637,112
Ensembl chr17:81,556,887...81,648,465 		JBrowse link
G OPTN optineurin enables IEA
IBA		 Ensembl
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G OTUD7A OTU deubiquitinase 7A enables IBA GO_Central GO_REF:0000033 NCBI chr15:31,475,398...31,870,673
Ensembl chr15:31,475,398...31,870,789 		JBrowse link
G OTUD7B OTU deubiquitinase 7B enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:149,937,812...150,067,653
Ensembl chr 1:149,937,812...150,010,726 		JBrowse link
G PARP10 poly(ADP-ribose) polymerase family member 10 enables IMP (PMID:23575687) UniProt PMID:23575687 NCBI chr 8:143,977,158...144,012,764
Ensembl chr 8:143,977,153...144,012,772 		JBrowse link
G PRPF8 pre-mRNA processing factor 8 enables IDA (PMID:20595234) UniProt PMID:20595234 NCBI chr17:1,650,629...1,684,867
Ensembl chr17:1,650,629...1,684,867 		JBrowse link
G RNF168 ring finger protein 168 enables IDA (PMID:19500350), (PMID:21041483), (PMID:22742833) UniProt PMID:19500350 PMID:21041483 PMID:22742833 NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768 		JBrowse link
G RNF169 ring finger protein 169 enables IDA (PMID:22492721), (PMID:22733822), (PMID:22742833) UniProt PMID:22492721 PMID:22733822 PMID:22742833 NCBI chr11:74,748,849...74,842,413
Ensembl chr11:74,748,849...74,842,413 		JBrowse link
G RNF31 ring finger protein 31 enables IBA GO_Central GO_REF:0000033 NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660 		JBrowse link
G SPRTN SprT-like N-terminal domain enables IDA (PMID:22681887), (PMID:23042605) UniProt PMID:22681887 PMID:23042605 NCBI chr 1:231,338,293...231,355,023
Ensembl chr 1:231,337,104...231,355,023 		JBrowse link
G SQSTM1 sequestosome 1 enables IEA
IBA
IDA		 (PMID:28404643), (PMID:29343546), (PMID:36221902) Ensembl
GO_Central
UniProt		 PMID:28404643 PMID:29343546 PMID:36221902 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 enables IDA
IBA
IEA		 (PMID:15327770), (PMID:19935683), (PMID:22158122) UniProt
GO_Central
TreeGrafter		 PMID:15327770 PMID:19935683 PMID:22158122 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:149,217,926...149,411,607
Ensembl chr 6:149,218,641...149,411,613 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 enables IDA (PMID:15327770), (PMID:22158122) UniProt PMID:15327770 PMID:22158122 NCBI chr  X:30,827,442...30,889,254
Ensembl chr  X:30,827,442...30,975,084 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 enables IDA
IBA
IEA		 (PMID:17525341), (PMID:17525342), (PMID:19261749), (PMID:22742833) UniProt
GO_Central
InterPro		 PMID:17525341 PMID:17525342 PMID:19261749 PMID:22742833 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:176,905,005...177,022,602
Ensembl chr 5:176,905,005...177,022,633 		JBrowse link
G WDR81 WD repeat domain 81 enables IDA (PMID:28404643) UniProt PMID:28404643 NCBI chr17:1,716,523...1,738,585
Ensembl chr17:1,716,523...1,738,599 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 enables IDA (PMID:24657165) UniProt PMID:24657165 NCBI chr14:64,503,716...64,533,693
Ensembl chr14:64,503,712...64,533,690 		JBrowse link
G ZRANB1 zinc finger RANBP2-type containing 1 enables IDA
IBA		 (PMID:18281465) BHF-UCL
GO_Central		 PMID:18281465 GO_REF:0000033 NCBI chr10:124,916,894...124,988,189
Ensembl chr10:124,942,123...124,988,189 		JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 enables IDA (PMID:22704558), (PMID:22705370), (PMID:22759634) UniProt PMID:22704558 PMID:22705370 PMID:22759634 NCBI chr 2:135,196,969...135,531,218
Ensembl chr 2:135,136,916...135,531,218 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19567
    binding 17961
      protein binding 15451
        modification-dependent protein binding 197
          polyubiquitin modification-dependent protein binding 59
            K63-linked polyubiquitin modification-dependent protein binding 26
paths to the root