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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of DNA-templated transcription, elongation
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Accession:GO:0032785 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
Synonyms:exact_synonym: negative regulation of DNA-dependent transcription, elongation
 broad_synonym: down regulation of RNA elongation;   downregulation of RNA elongation;   inhibition of RNA elongation;   negative regulation of transcription elongation;   negative regulation of transcriptional elongation
 related_synonym: negative transcription elongation regulator activity

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negative regulation of DNA-templated transcription, elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit involved_in ISO (PMID:9450929), (PMID:9857195) UniProt PMID:9450929 PMID:9857195 NCBI chrNW_004955451:4,682,308...4,688,008
Ensembl chrNW_004955451:4,682,311...4,688,008 		JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit involved_in ISO (PMID:10075709)
(PMID:9450929)		 UniProt PMID:9450929 PMID:10075709 NCBI chrNW_004955468:95,997...123,005
Ensembl chrNW_004955468:95,181...123,147 		JBrowse link
G Wdr82 WD repeat domain 82 involved_in ISO (PMID:33913806)
(MGI:6867107|PMID:33767452)		 UniProt PMID:33767452 PMID:33913806 MGI:6867107 NCBI chrNW_004955532:3,860,785...3,880,714
Ensembl chrNW_004955532:3,863,492...3,880,713 		JBrowse link
G Zc3h4 zinc finger CCCH-type containing 4 involved_in ISO (PMID:33913806)
(MGI:6867107|PMID:33767452)		 UniProt PMID:33767452 PMID:33913806 MGI:6867107 NCBI chrNW_004955574:1,029,343...1,069,412
Ensembl chrNW_004955574:1,029,438...1,067,225 		JBrowse link
negative regulation of transcription elongation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 acts_upstream_of_or_within ISO (PMID:10318824), (PMID:19204372) MGI PMID:10318824 PMID:19204372 NCBI chrNW_004955442:16,845,728...16,898,301
Ensembl chrNW_004955442:16,843,152...16,898,430 		JBrowse link
G Eapp E2F associated phosphoprotein acts_upstream_of_or_within ISO (PMID:15716352) MGI PMID:15716352 NCBI chrNW_004955409:26,383,618...26,411,738
Ensembl chrNW_004955409:26,383,732...26,414,568 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:10490622) UniProt PMID:10490622 NCBI chrNW_004955406:8,000,269...8,021,554
Ensembl chrNW_004955406:8,000,269...8,021,554 		JBrowse link
G Nelfa negative elongation factor complex member A involved_in
acts_upstream_of_or_within		 ISO (PMID:12612062)
(PMID:21670248)		 ComplexPortal
MGI		 PMID:12612062 PMID:21670248 NCBI chrNW_004955514:1,162,993...1,173,278
Ensembl chrNW_004955514:1,162,993...1,173,278 		JBrowse link
G Nelfb negative elongation factor complex member B involved_in ISO (MGI:3845453|PMID:19340312), (MGI:5576446|PMID:24656816), (MGI:6270977|PMID:25773599)
(PMID:12612062)		 UniProt
ComplexPortal		 PMID:12612062 PMID:19340312 PMID:24656816 PMID:25773599 MGI:3845453 MGI:5576446 MGI:6270977 NCBI chrNW_004955513:5,248,190...5,261,018
Ensembl chrNW_004955513:5,248,190...5,262,044 		JBrowse link
G Nelfcd negative elongation factor complex member C/D involved_in ISO (PMID:12612062) ComplexPortal PMID:12612062 NCBI chrNW_004955445:597,826...610,134
Ensembl chrNW_004955445:597,826...610,134 		JBrowse link
G Nelfe negative elongation factor complex member E involved_in
acts_upstream_of_or_within		 ISO (PMID:12612062), (PMID:14701750), (PMID:27256882)
(PMID:21670248)
(PMID:31399344)		 UniProt
MGI		 PMID:12612062 PMID:14701750 PMID:21670248 PMID:27256882 PMID:31399344 NCBI chrNW_004955437:467,018...473,084
Ensembl chrNW_004955437:466,690...473,084 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35393539) UniProt PMID:35393539 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in ISO (PMID:23748380) UniProt PMID:23748380 NCBI chrNW_004955506:6,574,802...6,612,763
Ensembl chrNW_004955506:6,575,408...6,612,186 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (PMID:20550933) UniProt PMID:20550933 NCBI chrNW_004955420:12,656,815...12,676,836
Ensembl chrNW_004955420:12,657,272...12,676,426 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (PMID:20550933) UniProt PMID:20550933 NCBI chrNW_004955437:5,807,592...5,832,213
Ensembl chrNW_004955437:5,809,082...5,832,057 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:17284610) MGI PMID:17284610 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:6214653|PMID:25247314), (PMID:31399344) UniProt PMID:25247314 PMID:31399344 MGI:6214653 NCBI chrNW_004955495:4,641,883...4,650,518
Ensembl chrNW_004955495:4,644,023...4,650,083 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit acts_upstream_of_or_within ISO (PMID:21670248) MGI PMID:21670248 NCBI chrNW_004955451:4,682,308...4,688,008
Ensembl chrNW_004955451:4,682,311...4,688,008 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:7660122) UniProt PMID:7660122 NCBI chrNW_004955561:1,573,525...1,578,295
Ensembl chrNW_004955561:1,573,525...1,580,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12352
    metabolic process 7468
      organic substance metabolic process 7149
        macromolecule metabolic process 6003
          macromolecule biosynthetic process 4619
            RNA biosynthetic process 2271
              DNA-templated transcription elongation 70
                negative regulation of DNA-templated transcription, elongation 19
                  negative regulation of transcription elongation by RNA polymerase I 0
                  negative regulation of transcription elongation by RNA polymerase II 16
Path 2
Term Annotations click to browse term
  biological_process 12352
    metabolic process 7468
      organic substance metabolic process 7149
        organic cyclic compound metabolic process 4094
          nucleobase-containing compound metabolic process 3737
            nucleic acid metabolic process 3370
              RNA metabolic process 2899
                RNA biosynthetic process 2271
                  DNA-templated transcription 2249
                    DNA-templated transcription elongation 70
                      regulation of DNA-templated transcription elongation 49
                        negative regulation of DNA-templated transcription, elongation 19
                          negative regulation of transcription elongation by RNA polymerase I 0
                          negative regulation of transcription elongation by RNA polymerase II 16
paths to the root