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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of interleukin-12 production
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Accession:GO:0032695 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.
Synonyms:exact_synonym: down regulation of interleukin-12 production;   downregulation of interleukin-12 production;   negative regulation of IL-12 production
 narrow_synonym: inhibition of interleukin-12 production;   negative regulation of interleukin-12 biosynthetic process;   negative regulation of interleukin-12 secretion
 related_synonym: negative regulation of CLMF production;   negative regulation of NKSF production
 alt_id: GO:0045083;   GO:2001183


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negative regulation of interleukin-12 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11168643) Ensembl
MGI
PMID:11168643 GO_REF:0000107 NCBI chrNW_004936659:1,598,252...1,642,615
Ensembl chrNW_004936659:1,598,177...1,600,262
JBrowse link
G Arrb2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:3,173,054...3,181,475
Ensembl chrNW_004936677:3,172,925...3,181,520
JBrowse link
G C1qbp complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:2,371,400...2,376,608
Ensembl chrNW_004936677:2,371,418...2,376,608
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 acts_upstream_of
involved_in
ISO
IEA
(MGI:4441559|PMID:20176793) BHF-UCL
Ensembl
PMID:20176793 GO_REF:0000107 MGI:4441559 NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757
JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in ISO (MGI:5009414|PMID:15753205) UniProt PMID:15753205 MGI:5009414 NCBI chrNW_004936769:302,391...304,166 JBrowse link
G Il10 interleukin 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15240714) Ensembl
MGI
PMID:15240714 GO_REF:0000107 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:4,233,353...4,284,324
Ensembl chrNW_004936545:4,233,358...4,282,806
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004936596:3,212,593...3,224,426
Ensembl chrNW_004936596:3,212,593...3,224,048
JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:20041150) BHF-UCL PMID:20041150 NCBI chrNW_004936694:970,706...980,605 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14568984) Ensembl
MGI
PMID:14568984 GO_REF:0000107 NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435
JBrowse link
G Nlrc3 NLR family CARD domain containing 3 involved_in ISO (MGI:5437524|PMID:22863753) CACAO PMID:22863753 MGI:5437524 NCBI chrNW_004936694:757,121...773,924 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15220916), (PMID:16949315) Ensembl
MGI
PMID:15220916 PMID:16949315 GO_REF:0000107 NCBI chrNW_004936475:3,708,069...3,742,845
Ensembl chrNW_004936475:3,713,362...3,745,982
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936511:7,860,552...8,082,850
Ensembl chrNW_004936511:7,860,590...8,081,525
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936740:55,941...92,100
Ensembl chrNW_004936740:55,941...92,100
JBrowse link
G Thbs1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:3,064,466...3,081,125
Ensembl chrNW_004936471:3,064,422...3,081,949
JBrowse link
G Tigit T cell immunoreceptor with Ig and ITIM domains involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936536:1,731,352...1,746,843
Ensembl chrNW_004936536:1,731,352...1,746,763
JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:16949315) MGI PMID:16949315 NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
JBrowse link
G Tlr8 toll like receptor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:2,638,020...2,642,201
Ensembl chrNW_004936470:2,638,014...2,641,133
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15971
    multicellular organismal process 7395
      negative regulation of multicellular organismal process 1173
        negative regulation of cytokine production 288
          negative regulation of interleukin-12 production 18
Path 2
Term Annotations click to browse term
  biological_process 15971
    biological regulation 11164
      regulation of biological process 10824
        regulation of metabolic process 5605
          regulation of biosynthetic process 4527
            regulation of cellular biosynthetic process 4441
              regulation of macromolecule biosynthetic process 4346
                regulation of gene expression 4234
                  regulation of cytokine production 737
                    negative regulation of cytokine production 288
                      negative regulation of interleukin-12 production 18
paths to the root