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ONTOLOGY REPORT - ANNOTATIONS

Term:establishment of endothelial blood-brain barrier
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Accession:GO:0014045 term browser browse the term
Definition:Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
Synonyms:exact_synonym: establishment of endothelial BBB


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establishment of endothelial blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLDN3 claudin 3 involved_in ISO (MGI:6368952|PMID:12734665) ARUK-UCL PMID:12734665 MGI:6368952 NCBI chr 3:11,019,073...11,020,102
Ensembl chr 3:11,019,073...11,020,102 		JBrowse link
G FOXP3 forkhead box P3 ISO RGD PMID:31027862 RGD:38549575 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17806
    developmental process 6728
      anatomical structure development 6324
        cell development 3224
          establishment of blood-brain barrier 19
            establishment of endothelial blood-brain barrier 2
Path 2
Term Annotations click to browse term
  biological_process 17806
    developmental process 6728
      anatomical structure development 6324
        tissue development 2232
          epithelium development 1385
            endothelium development 160
              endothelial cell differentiation 136
                endothelial cell development 80
                  establishment of endothelial barrier 58
                    establishment of endothelial blood-brain barrier 2
paths to the root