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ONTOLOGY REPORT - ANNOTATIONS

Term:endothelium development
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Accession:GO:0003158 term browser browse the term
Definition:The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.


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endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 acts_upstream_of_or_within ISO (PMID:18506003) RGD PMID:18506003 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO
IEA 		MGI:1856982 (PMID:12485443)
GO_REF:0000107 		RGD
Ensembl		 PMID:12485443 GO_REF:0000107 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Cd2ap CD2-associated protein acts_upstream_of_or_within ISO MGI:2664945 (PMID:25968128) RGD PMID:25968128 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Cd34 CD34 molecule involved_in ISO (PMID:17261663) RGD PMID:17261663 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 acts_upstream_of_or_within ISO (PMID:18506003) RGD PMID:18506003 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Gja1 gap junction protein, alpha 1 IEP RGD PMID:10990491 RGD:7207853 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja4 gap junction protein, alpha 4 IEP RGD PMID:10990491 RGD:7207853 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925 		JBrowse link
G Gja5 gap junction protein, alpha 5 IEP RGD PMID:10990491 RGD:7207853 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Kdr kinase insert domain receptor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:7596435) 		UniProt
Ensembl
RGD		 PMID:7596435 GO_REF:0000024 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO
IEA 		MGI:1934018 (PMID:21408219)
GO_REF:0000107 		RGD
Ensembl		 PMID:21408219 GO_REF:0000107 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 acts_upstream_of_or_within ISO
IEA 		MGI:1889622 (PMID:15342464)
GO_REF:0000107 		RGD
Ensembl		 PMID:15342464 GO_REF:0000107 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
arterial endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9QUS4 (PMID:15107403) RGD PMID:15107403 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO
IEA 		UniProtKB:Q9WV93 (PMID:15107403)
GO_REF:0000107 		RGD
Ensembl		 PMID:15107403 GO_REF:0000107 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA 		(PMID:15107403)
GO_REF:0000107 		RGD
Ensembl		 PMID:15107403 GO_REF:0000107 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO
IEA 		MGI:5432904|MGI:5432905 (PMID:22783020)
GO_REF:0000107 		RGD
Ensembl		 PMID:22783020 GO_REF:0000107 NCBI chr10:74,854,779...74,861,147
Ensembl chr10:74,854,468...74,862,941 		JBrowse link
arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:15466160) RGD PMID:15466160 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO
IEA 		MGI:3512761 (PMID:19151727)
GO_REF:0000107 		RGD
Ensembl		 PMID:19151727 GO_REF:0000107 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (PMID:15107403) RGD PMID:15107403 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO
IEA 		MGI:1341800 (PMID:15107403)
GO_REF:0000107 		RGD
Ensembl		 PMID:15107403 GO_REF:0000107 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within ISO
IEA 		MGI:3530468 (PMID:15644447)
GO_REF:0000107 		RGD
Ensembl		 PMID:15644447 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO
IEA 		MGI:6364606 (PMID:33357458)
GO_REF:0000107 		RGD
Ensembl		 PMID:33357458 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO
IEA 		MGI:2386336 (PMID:11927535)
GO_REF:0000107 		RGD
Ensembl		 PMID:11927535 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO UniProtKB:P52800 (PMID:15466160) RGD PMID:15466160 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
blood vessel lumenization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll4 delta like canonical Notch ligand 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15466160) 		Ensembl
RGD		 PMID:15466160 GO_REF:0000107 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:15466160) RGD PMID:15466160 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
endocardial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO
IEA 		(PMID:20890042)
GO_REF:0000107 		RGD
Ensembl		 PMID:20890042 GO_REF:0000107 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
IEA 		(PMID:17336907)
GO_REF:0000107 		RGD
Ensembl		 PMID:17336907 GO_REF:0000107 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21330551) 		Ensembl
RGD		 PMID:21330551 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO
IEA 		MGI:103559 (PMID:17610846)
GO_REF:0000107 		RGD
Ensembl		 PMID:17610846 GO_REF:0000107 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO MGI:107543 (PMID:17610846) RGD PMID:17610846 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
endocardial cushion cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA 		(PMID:19506109)
GO_REF:0000107 		RGD
Ensembl		 PMID:19506109 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
endothelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO
IEA 		MGI:1924696|MGI:3512761 (PMID:19151727)
GO_REF:0000107 		RGD
Ensembl		 PMID:19151727 GO_REF:0000107 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within ISO
IEA 		MGI:2158814 (PMID:16373599)
GO_REF:0000107 		RGD
Ensembl		 PMID:16373599 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within ISO MGI:2384924 (PMID:19151727) RGD PMID:19151727 NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 acts_upstream_of_or_within ISO
IEA 		MGI:3583268 (PMID:15882861)
GO_REF:0000107 		RGD
Ensembl		 PMID:15882861 GO_REF:0000107 NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111 		JBrowse link
endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Barx1 BARX homeobox 1 acts_upstream_of_or_within ISO
IEA 		(PMID:15809042)
GO_REF:0000107 		RGD
Ensembl		 PMID:15809042 GO_REF:0000107 NCBI chr17:15,990,412...15,993,887
Ensembl chr17:15,990,412...15,993,887 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:24955809 RGD:11352686 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Fstl1 follistatin-like 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20054002) 		UniProt
RGD		 PMID:20054002 GO_REF:0000024 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G Fzd1 frizzled class receptor 1 acts_upstream_of_or_within ISO MGI:103124 (PMID:15809042) RGD PMID:15809042 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Fzd2 frizzled class receptor 2 acts_upstream_of_or_within ISO
IEA 		MGI:103124 (PMID:15809042)
GO_REF:0000107 		RGD
Ensembl		 PMID:15809042 GO_REF:0000107 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Fzd4 frizzled class receptor 4 acts_upstream_of_or_within ISO
IEA 		(PMID:23217714)
GO_REF:0000107 		RGD
Ensembl		 PMID:23217714 GO_REF:0000107 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Hoxb5 homeo box B5 acts_upstream_of_or_within ISO (PMID:12897140) RGD PMID:12897140 NCBI chr10:81,269,372...81,271,580
Ensembl chr10:81,269,372...81,271,580 		JBrowse link
G Kdm6b lysine demethylase 6B involved_in ISO
IEA 		(PMID:23856522)
GO_REF:0000107 		RGD
Ensembl		 PMID:23856522 GO_REF:0000107 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794 		JBrowse link
G Kdr kinase insert domain receptor involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:12897140), (PMID:18772315) 		GO_Central
Ensembl
RGD		 PMID:12897140 PMID:18772315 GO_REF:0000033 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO
IEA 		(PMID:18297060)
GO_REF:0000107 		RGD
Ensembl		 PMID:18297060 GO_REF:0000107 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO
IEA 		(PMID:23217714)
GO_REF:0000107 		RGD
Ensembl		 PMID:23217714 GO_REF:0000107 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Notch4 notch receptor 4 IDA RGD PMID:10964583 RGD:1304484 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Ptn pleiotrophin IEP RGD PMID:20830586 RGD:9686141 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IEP RGD PMID:7959012 RGD:61573 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Setsip SET like protein involved_in ISO (PMID:22869753) RGD PMID:22869753 NCBI chr19:53,561,262...53,562,780
Ensembl chr19:53,561,190...53,563,819 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of ISO
IEA 		MGI:2136645|MGI:3608931 (PMID:25186293)
GO_REF:0000107 		RGD
Ensembl		 PMID:25186293 GO_REF:0000107 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeo box A13 acts_upstream_of_or_within ISO
IEA 		MGI:2152356 (PMID:18483557)
GO_REF:0000107 		RGD
Ensembl		 PMID:18483557 GO_REF:0000107 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
endothelial cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amotl2 angiomotin like 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:24806444) 		UniProt
RGD		 PMID:24806444 GO_REF:0000024 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 acts_upstream_of_or_within ISO
IEA 		MGI:5500046 (PMID:23372835)
GO_REF:0000107 		RGD
Ensembl		 PMID:23372835 GO_REF:0000107 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO
IEA 		(PMID:24806444)
GO_REF:0000107 		RGD
Ensembl		 PMID:24806444 GO_REF:0000107 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Clic4 chloride intracellular channel 4 acts_upstream_of_or_within ISO
IEA 		MGI:3838012 (PMID:19197003)
GO_REF:0000107 		RGD
Ensembl		 PMID:19197003 GO_REF:0000107 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Cnmd chondromodulin acts_upstream_of_or_within ISO (PMID:12714610) RGD PMID:12714610 NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:15188432) 		GO_Central
RGD		 PMID:15188432 GO_REF:0000033 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within ISO MGI:3838392 (PMID:19151727) RGD PMID:19151727 NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051 		JBrowse link
G Hoxa13 homeo box A13 acts_upstream_of_or_within ISO
IEA 		MGI:2152356 (PMID:18483557)
GO_REF:0000107 		RGD
Ensembl		 PMID:18483557 GO_REF:0000107 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
G Id1 inhibitor of DNA binding 1 acts_upstream_of_or_within ISO
IEA 		MGI:2679939 (PMID:17717145)
GO_REF:0000107 		RGD
Ensembl		 PMID:17717145 GO_REF:0000107 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:2157527 (PMID:21285373) RGD PMID:21285373 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:24806444) 		UniProt
RGD		 PMID:24806444 GO_REF:0000024 NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA 		(PMID:14500721)
GO_REF:0000107 		RGD
Ensembl		 PMID:14500721 GO_REF:0000107 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Notch4 notch receptor 4 IDA RGD PMID:10964583 RGD:1304484 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 acts_upstream_of_or_within ISO
IEA 		MGI:2677448 (PMID:17563397)
GO_REF:0000107 		RGD
Ensembl		 PMID:17563397 GO_REF:0000107 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 acts_upstream_of_or_within ISO
IEA 		MGI:3620600|MGI:3620601 (PMID:16467571)
GO_REF:0000107 		RGD
Ensembl		 PMID:16467571 GO_REF:0000107 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO
IEA 		(PMID:14500721)
GO_REF:0000107 		RGD
Ensembl		 PMID:14500721 GO_REF:0000107 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Tnmd tenomodulin acts_upstream_of_or_within ISO
IEA 		(PMID:12714610)
GO_REF:0000107 		RGD
Ensembl		 PMID:12714610 GO_REF:0000107 NCBI chr  X:97,057,137...97,072,634
Ensembl chr  X:97,057,137...97,072,634 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:22282195) 		UniProt
RGD		 PMID:22282195 GO_REF:0000024 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) RGD PMID:32369453 NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353 		JBrowse link
endothelial tube lumen extension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO
IEA 		UniProtKB:Q9Y3M8 (PMID:20208559)
GO_REF:0000107 		RGD
Ensembl		 PMID:20208559 GO_REF:0000107 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 acts_upstream_of_or_within ISO
IEA 		UniProtKB:P61586 (PMID:20208559)
GO_REF:0000107 		RGD
Ensembl		 PMID:20208559 GO_REF:0000107 NCBI chr12:566,282...959,372
Ensembl chr12:566,310...959,421 		JBrowse link
endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19592636) RGD PMID:19592636 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Bsg basigin involved_in ISO
ISS 		(PMID:19837976)
GO_REF:0000024 		RGD
UniProt		 PMID:19837976 GO_REF:0000024 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO
IEA 		(PMID:19151727)
GO_REF:0000107 		RGD
Ensembl		 PMID:19151727 GO_REF:0000107 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO (PMID:19592636) RGD PMID:19592636 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS 		(PMID:20123964)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:20123964 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:24955809 RGD:11352686 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:25942475 RGD:126925211 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:21347332) RGD PMID:21347332 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Rhob ras homolog family member B involved_in ISO
IEA 		(PMID:21347332)
GO_REF:0000107 		RGD
Ensembl		 PMID:21347332 GO_REF:0000107 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
establishment of blood-nerve barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2136636 (PMID:9734405) RGD PMID:9734405 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Cldn1 claudin 1 IMP RGD PMID:22733753 RGD:11341802 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Dmd dystrophin acts_upstream_of_or_within ISO
IEA 		MGI:1856328 (PMID:12673830)
GO_REF:0000107 		RGD
Ensembl		 PMID:12673830 GO_REF:0000107 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 acts_upstream_of_or_within ISO MGI:4437572 (PMID:20181608) RGD PMID:20181608 NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588 		JBrowse link
G Ren renin NOT|acts_upstream_of_or_within ISO MGI:2136642 (PMID:10617578) RGD PMID:10617578 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn5 claudin 5 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within ISO (PMID:27026367) RGD PMID:27026367 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO 		GO_REF:0000107
(PMID:27026367) 		Ensembl
RGD		 PMID:27026367 GO_REF:0000107 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO
IEA 		(PMID:27026367)
GO_REF:0000107 		RGD
Ensembl		 PMID:27026367 GO_REF:0000107 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Ezr ezrin involved_in ISO
IEA 		UniProtKB:P26038|UniProtKB:P35241 (PMID:23264465)
GO_REF:0000107 		RGD
Ensembl		 PMID:23264465 GO_REF:0000107 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:20826780)
GO_REF:0000107 		RGD
Ensembl		 PMID:20826780 GO_REF:0000107 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hpse heparanase involved_in IEA
ISO 		GO_REF:0000107
(PMID:27026367) 		Ensembl
RGD		 PMID:27026367 GO_REF:0000107 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO UniProtKB:Q96S97 (PMID:23264465) RGD PMID:23264465 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Marveld2 MARVEL domain containing 2 involved_in ISO
IEA 		(PMID:23073616)
GO_REF:0000107 		RGD
Ensembl		 PMID:23073616 GO_REF:0000107 NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Msn moesin involved_in ISO
IEA 		UniProtKB:P15311|UniProtKB:P35241 (PMID:23264465)
GO_REF:0000107 		RGD
Ensembl		 PMID:23264465 GO_REF:0000107 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Myadm myeloid-associated differentiation marker involved_in ISO
IEA 		(PMID:23264465)
GO_REF:0000107 		RGD
Ensembl		 PMID:23264465 GO_REF:0000107 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IDA PMID:20139324 UniProt PMID:20139324 RGD:8553884 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IDA PMID:20139324 UniProt PMID:20139324 RGD:8553884 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO
IEA 		(PMID:7589563)
GO_REF:0000107 		RGD
Ensembl		 PMID:7589563 GO_REF:0000107 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:18586956)
GO_REF:0000107
(PMID:21907835)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18586956 PMID:21907835 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in ISO
IEA
ISS 		(PMID:21840392)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21840392 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family involved_in ISO
ISS 		(PMID:21840392)
GO_REF:0000024 		RGD
UniProt		 PMID:21840392 GO_REF:0000024 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 involved_in ISO (PMID:21840392) RGD PMID:21840392 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:21840392) 		UniProt
RGD		 PMID:21840392 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISO
IEA
ISS 		(PMID:21840392)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21840392 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
G Rdx radixin involved_in ISO
IEA 		UniProtKB:P15311|UniProtKB:P26038 (PMID:23264465)
GO_REF:0000107 		RGD
Ensembl		 PMID:23264465 GO_REF:0000107 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Robo4 roundabout guidance receptor 4 involved_in ISO
IEA 		(PMID:30455415)
GO_REF:0000107 		RGD
Ensembl		 PMID:30455415 GO_REF:0000107 NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519 		JBrowse link
G Sox18 SRY-box transcription factor 18 involved_in ISO
IEA 		(PMID:18065521)
GO_REF:0000107 		RGD
Ensembl		 PMID:18065521 GO_REF:0000107 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
establishment of endothelial blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B IMP RGD PMID:16850390 RGD:1598561 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Cldn3 claudin 3 involved_in ISO
IEA 		(PMID:12734665)
GO_REF:0000107 		RGD
Ensembl		 PMID:12734665 GO_REF:0000107 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Foxp3 forkhead box P3 IEP RGD PMID:31027862 RGD:38549575 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
establishment of endothelial intestinal barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07006111.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:202,534,573...202,536,183 JBrowse link
G Afdn afadin, adherens junction formation factor involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 1:53,905,344...54,034,216
Ensembl chr 1:53,905,373...54,034,216 		JBrowse link
G Cldn1 claudin 1 IMP RGD PMID:22684624 RGD:11341733 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G F11r F11 receptor involved_in ISO
IBA 		UniProtKB:Q9Y3L5 (PMID:23885123)
GO_REF:0000033 		RGD
GO_Central		 PMID:23885123 GO_REF:0000033 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Fasn fatty acid synthase acts_upstream_of_or_within ISO
IEA 		MGI:3765070 (PMID:25565205)
GO_REF:0000107 		RGD
Ensembl		 PMID:25565205 GO_REF:0000107 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IMP RGD PMID:10201790 RGD:11520782 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Mir874 microRNA 874 acts_upstream_of_or_within ISO (PMID:24462679) RGD PMID:24462679 NCBI chr17:6,620,649...6,620,724
Ensembl chr17:6,620,649...6,620,724 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO
IEA 		MGI:2385681 (PMID:22155109)
GO_REF:0000107 		RGD
Ensembl		 PMID:22155109 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S acts_upstream_of_or_within ISO MGI:2158734 (PMID:24385580) RGD PMID:24385580 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947 		JBrowse link
G Rab1a RAB1A, member RAS oncogene family NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
Ensembl chr  X:202,405,759...202,413,868 		JBrowse link
G Rap2b RAP2B, member of RAS oncogene family NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069 		JBrowse link
G Rap2c RAP2C, member of RAS oncogene family involved_in ISO
IEA 		UniProtKB:Q9Y624 (PMID:23885123)
GO_REF:0000107 		RGD
Ensembl		 PMID:23885123 GO_REF:0000107 NCBI chr  X:130,504,554...130,517,671
Ensembl chr  X:130,504,698...130,518,328 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rapgef6 Rap guanine nucleotide exchange factor 6 NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr10:38,655,854...38,824,227
Ensembl chr10:38,655,867...38,823,211 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO
IBA 		(PMID:23885123)
GO_REF:0000033 		RGD
GO_Central		 PMID:23885123 GO_REF:0000033 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 involved_in ISO
IBA 		(PMID:23885123)
GO_REF:0000033 		RGD
GO_Central		 PMID:23885123 GO_REF:0000033 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279 		JBrowse link
glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO (PMID:17464107) RGD PMID:17464107 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
IEA 		(PMID:31402170)
GO_REF:0000107 		RGD
Ensembl		 PMID:31402170 GO_REF:0000107 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO 		GO_REF:0000107
(PMID:31402170) 		Ensembl
RGD		 PMID:31402170 GO_REF:0000107 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1857740 (PMID:16498405) RGD PMID:16498405 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO
IEA 		(PMID:17464107)
GO_REF:0000107 		RGD
Ensembl		 PMID:17464107 GO_REF:0000107 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
lymphatic endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B involved_in ISO
IEA 		(PMID:19903896)
GO_REF:0000107 		RGD
Ensembl		 PMID:19903896 GO_REF:0000107 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19903896) RGD PMID:19903896 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO
IEA 		(PMID:19903896)
GO_REF:0000107 		RGD
Ensembl		 PMID:19903896 GO_REF:0000107 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Prox1 prospero homeobox 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:12198161)
GO_REF:0000107
MGI:2182767|MGI:3609548 (PMID:19056883) 		RGD
Ensembl		 PMID:12198161 PMID:19056883 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO
IEA 		MGI:2178809 (PMID:18931657)
GO_REF:0000107 		RGD
Ensembl		 PMID:18931657 GO_REF:0000107 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 acts_upstream_of_or_within ISO
IEA 		(PMID:20223757)
GO_REF:0000107 		RGD
Ensembl		 PMID:20223757 GO_REF:0000107 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592 		JBrowse link
lymphatic endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 involved_in ISO
IEA 		(PMID:18815287)
GO_REF:0000107 		RGD
Ensembl		 PMID:18815287 GO_REF:0000107 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Pdpn podoplanin involved_in ISS
ISO 		GO_REF:0000024
(PMID:20110424) 		UniProt
RGD		 PMID:20110424 GO_REF:0000024 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO
IEA 		(PMID:18815287)
GO_REF:0000107 		RGD
Ensembl		 PMID:18815287 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 involved_in ISO
IEA 		(PMID:24792364)
GO_REF:0000107 		RGD
Ensembl		 PMID:24792364 GO_REF:0000107 NCBI chr 4:156,047,043...156,073,540
Ensembl chr 4:156,046,969...156,073,518 		JBrowse link
negative regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:20406889) RGD PMID:20406889 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Dsg2 desmoglein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:27338829) 		Ensembl
RGD		 PMID:27338829 GO_REF:0000107 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156 		JBrowse link
G Id1 inhibitor of DNA binding 1 IMP RGD PMID:20830586 RGD:9686141 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:25535084) 		Ensembl
RGD		 PMID:25535084 GO_REF:0000107 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Mir1 microRNA 1 involved_in ISO (PMID:23939491) RGD PMID:23939491 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir1a-1 microRNA 1a-1 involved_in ISO (PMID:23939491) RGD PMID:23939491 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Notch4 notch receptor 4 involved_in ISO (PMID:11344305) RGD PMID:11344305 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IMP RGD PMID:17450384 RGD:2302022 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO
IEA 		MGI:2136645|MGI:3608931 (PMID:25186293)
GO_REF:0000107 		RGD
Ensembl		 PMID:25186293 GO_REF:0000107 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in ISO (PMID:23765923) RGD PMID:23765923 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
negative regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S1pr3 sphingosine-1-phosphate receptor 3 involved_in ISO (PMID:24851274) RGD PMID:24851274 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA 		(PMID:20048167)
GO_REF:0000107 		RGD
Ensembl		 PMID:20048167 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:19144989) 		UniProt
RGD		 PMID:19144989 GO_REF:0000024 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
positive regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir34a microRNA 34a involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
positive regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:20406889) RGD PMID:20406889 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 involved_in ISO
IEA 		(PMID:24463812)
GO_REF:0000107 		RGD
Ensembl		 PMID:24463812 GO_REF:0000107 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20406889) 		Ensembl
RGD		 PMID:20406889 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO
IEA 		(PMID:20406889)
GO_REF:0000107 		RGD
Ensembl		 PMID:20406889 GO_REF:0000107 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15033446) 		UniProt
Ensembl
RGD		 PMID:15033446 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO
IEA 		MGI:2148567 (PMID:18231602)
GO_REF:0000107 		RGD
Ensembl		 PMID:18231602 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Etv2 ETS variant transcription factor 2 acts_upstream_of_or_within ISO
IEA 		(PMID:18462699)
GO_REF:0000107 		RGD
Ensembl		 PMID:18462699 GO_REF:0000107 NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431 		JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO
IEA 		(PMID:20406889)
GO_REF:0000107 		RGD
Ensembl		 PMID:20406889 GO_REF:0000107 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Mir126a microRNA 126a IDA RGD PMID:32160957 RGD:401851064 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir150 microRNA 150 involved_in ISO (PMID:23765923) RGD PMID:23765923 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO RNAcentral:URS0000241987_9606|RNAcentral:URS00003DA300_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Mir181b1 microRNA 181b-1 involved_in ISO RNAcentral:URS0000229622_9606|RNAcentral:URS0000605E00_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 involved_in ISO RNAcentral:URS0000229622_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:23765923) RGD PMID:23765923 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:24356956) RGD PMID:24356956 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir99b microRNA 99b involved_in ISO RNAcentral:URS00001C308D_9606|RNAcentral:URS00002C10B3_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090 		JBrowse link
G Mrtfa myocardin related transcription factor A IMP RGD PMID:23624342 RGD:529317032 NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418 		JBrowse link
G Notch1 notch receptor 1 IMP RGD PMID:19109527 RGD:2325303 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Tmem100 transmembrane protein 100 involved_in ISO
IEA 		(PMID:22783020)
GO_REF:0000107 		RGD
Ensembl		 PMID:22783020 GO_REF:0000107 NCBI chr10:74,854,779...74,861,147
Ensembl chr10:74,854,468...74,862,941 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 involved_in ISO
IEA 		(PMID:27538588)
GO_REF:0000107 		RGD
Ensembl		 PMID:27538588 GO_REF:0000107 NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111 		JBrowse link
positive regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:10733500 RGD:2313864 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Itgax integrin subunit alpha X involved_in ISO
IEA 		(PMID:30873824)
GO_REF:0000107 		RGD
Ensembl		 PMID:30873824 GO_REF:0000107 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:31759996 RGD:41410819 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
positive regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in ISO
IEA
IBA 		(PMID:25978380)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:25978380 GO_REF:0000033 GO_REF:0000107 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Akap11 A-kinase anchoring protein 11 IMP RGD PMID:25188285 RGD:14348953 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO
IEA 		(PMID:23288152)
GO_REF:0000107 		RGD
Ensembl		 PMID:23288152 GO_REF:0000107 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cldn5 claudin 5 involved_in ISO
IEA 		(PMID:23288152)
GO_REF:0000107 		RGD
Ensembl		 PMID:23288152 GO_REF:0000107 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Dicer1 dicer 1 ribonuclease III IMP RGD PMID:23239824 RGD:149735901 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G F11r F11 receptor involved_in ISO (PMID:26985018) RGD PMID:26985018 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa involved_in ISO
ISS 		(PMID:25651845)
GO_REF:0000024 		RGD
UniProt		 PMID:25651845 GO_REF:0000024 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 involved_in ISO (PMID:24851274) RGD PMID:24851274 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574 		JBrowse link
regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apold1 apolipoprotein L domain containing 1 involved_in IEP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:15102925 GO_REF:0000033, RGD:1303988 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (PMID:20406889) RGD PMID:20406889 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16680193) 		UniProt
RGD		 PMID:16680193 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 TAS RGD PMID:12183510 RGD:727411 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO (PMID:18772315) RGD PMID:18772315 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO
IEA 		(PMID:17895370)
GO_REF:0000107 		RGD
Ensembl		 PMID:17895370 GO_REF:0000107 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO
IEA 		(PMID:16484616)
GO_REF:0000107 		RGD
Ensembl		 PMID:16484616 GO_REF:0000107 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23469107) 		UniProt
RGD		 PMID:23469107 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO
IEA 		(PMID:24023716)
GO_REF:0000107 		RGD
Ensembl		 PMID:24023716 GO_REF:0000107 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:27653213) 		Ensembl
RGD		 PMID:27653213 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A NOT|involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA 		UniProtKB:O75116 (PMID:25816133)
GO_REF:0000107 		RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133) 		Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA 		(PMID:25816133)
GO_REF:0000107 		RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO
IEA 		(PMID:25816133)
GO_REF:0000107 		RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Vcl vinculin involved_in IEA
ISO 		GO_REF:0000107
(PMID:26923917) 		Ensembl
RGD		 PMID:26923917 GO_REF:0000107 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 involved_in ISO
IEA 		(PMID:27653213)
GO_REF:0000107 		RGD
Ensembl		 PMID:27653213 GO_REF:0000107 NCBI chr 5:102,273,561...102,333,174
Ensembl chr 5:97,229,345...97,286,537 		JBrowse link
venous endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO
IEA 		(PMID:20890042)
GO_REF:0000107 		RGD
Ensembl		 PMID:20890042 GO_REF:0000107 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        tissue development 2325
          epithelium development 1451
            endothelium development 172
              endocardial endothelium development 0
              endothelial cell differentiation + 147
              glomerular endothelium development + 6
              morphogenesis of an endothelium + 20
paths to the root