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ONTOLOGY REPORT - ANNOTATIONS

Term:endothelium development
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Accession:GO:0003158 term browser browse the term
Definition:The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.

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endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO (PMID:17261663) RGD PMID:17261663 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Gja1 gap junction protein, alpha 1 IEP RGD PMID:10990491 RGD:7207853 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Gja4 gap junction protein, alpha 4 IEP RGD PMID:10990491 RGD:7207853 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221 		JBrowse link
G Gja5 gap junction protein, alpha 5 IEP RGD PMID:10990491 RGD:7207853 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939 		JBrowse link
G Kdr kinase insert domain receptor involved_in ISS
ISO		 GO_REF:0000024
(MGI:74276|PMID:7596435)		 UniProt
RGD		 PMID:7596435 GO_REF:0000024 MGI:74276 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 acts_upstream_of_or_within ISO MGI:1889622 (MGI:3578034|PMID:15342464) RGD PMID:15342464 MGI:3578034 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293 		JBrowse link
arterial endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9QUS4 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO UniProtKB:Q9WV93 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO MGI:5432904|MGI:5432905 (MGI:5432418|PMID:22783020) RGD PMID:22783020 MGI:5432418 NCBI chr10:77,537,340...77,543,710
Ensembl chr10:77,537,340...77,543,192 		JBrowse link
arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO MGI:3512761 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr14:86,812,728...86,859,408
Ensembl chr14:86,813,082...86,859,406 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO UniProtKB:P52800 (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
blood vessel lumenization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll4 delta like canonical Notch ligand 4 involved_in ISO (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
central nervous system vasculogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148569 (MGI:3821408|PMID:19023080)		 Ensembl
RGD		 PMID:19023080 GO_REF:0000107 MGI:3821408 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Eng endoglin involved_in ISO (PMID:7894484) RGD PMID:7894484 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5492189|PMID:23625008)		 UniProt
RGD		 PMID:23625008 GO_REF:0000024 MGI:5492189 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458 		JBrowse link
G Wnt7a Wnt family member 7A acts_upstream_of_or_within ISO MGI:98962 (MGI:3821408|PMID:19023080) RGD PMID:19023080 MGI:3821408 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609 		JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO MGI:98961 (MGI:3821408|PMID:19023080) RGD PMID:19023080 MGI:3821408 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723 		JBrowse link
endocardial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:17336907) RGD PMID:17336907 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4946551|PMID:21330551)		 Ensembl
RGD		 PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO MGI:103559 (MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:3716256 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO MGI:107543 (MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:3716256 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127 		JBrowse link
endocardial cushion cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA		 (PMID:19506109)
GO_REF:0000107		 RGD
Ensembl		 PMID:19506109 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930 		JBrowse link
endothelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO MGI:1924696|MGI:3512761 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr14:86,812,728...86,859,408
Ensembl chr14:86,813,082...86,859,406 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2158814 (MGI:3698597|PMID:16373599)		 Ensembl
RGD		 PMID:16373599 GO_REF:0000107 MGI:3698597 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within ISO MGI:2384924 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr11:70,234,248...70,322,966
Ensembl chr11:70,236,888...70,322,690 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:165,247,630...165,259,228
Ensembl chr 5:165,247,133...165,259,224 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 acts_upstream_of_or_within ISO MGI:3583268 (MGI:3581991|PMID:15882861) RGD PMID:15882861 MGI:3581991 NCBI chr10:75,365,763...75,382,014
Ensembl chr10:75,365,822...75,381,555 		JBrowse link
endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:24955809 RGD:11352686 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Fstl1 follistatin-like 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4457221|PMID:20054002)		 UniProt
RGD		 PMID:20054002 GO_REF:0000024 MGI:4457221 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418 		JBrowse link
G Hoxb5 homeo box B5 acts_upstream_of_or_within ISO (MGI:2670246|PMID:12897140) RGD PMID:12897140 MGI:2670246 NCBI chr10:84,152,152...84,154,360
Ensembl chr10:84,152,152...84,154,360 		JBrowse link
G Kdm6b lysine demethylase 6B involved_in ISO (MGI:5574281|PMID:23856522) RGD PMID:23856522 MGI:5574281 NCBI chr10:56,000,494...56,009,582
Ensembl chr10:56,001,799...56,008,885 		JBrowse link
G Kdr kinase insert domain receptor involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2670246|PMID:12897140), (MGI:5543371|PMID:18772315)		 RGD PMID:12897140 PMID:18772315, PMID:21873635 MGI:2670246 MGI:5543371, RGD:13792537 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (PMID:18297060) RGD PMID:18297060 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908 		JBrowse link
G Notch4 notch receptor 4 IDA RGD PMID:10964583 RGD:1304484 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785 		JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO MGI:2386336 (MGI:2177970|PMID:11927535) RGD PMID:11927535 MGI:2177970 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
G Ptn pleiotrophin IEP RGD PMID:20830586 RGD:9686141 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IEP RGD PMID:7959012 RGD:61573 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761 		JBrowse link
endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa13 homeo box A13 acts_upstream_of_or_within ISO MGI:2152356 (MGI:3797428|PMID:18483557) RGD PMID:18483557 MGI:3797428 NCBI chr 4:82,313,383...82,315,550
Ensembl chr 4:82,228,017...82,229,397 		JBrowse link
endothelial cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef26 Rho guanine nucleotide exchange factor 26 acts_upstream_of_or_within ISO MGI:5500046 (MGI:5486234|PMID:23372835) RGD PMID:23372835 MGI:5486234 NCBI chr 2:27,107,263...27,236,336
Ensembl chr 2:27,107,318...27,236,672 		JBrowse link
G Clic4 chloride intracellular channel 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3838012 (MGI:3837628|PMID:19197003)		 Ensembl
RGD		 PMID:19197003 GO_REF:0000107 MGI:3837628 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869 		JBrowse link
G Cnmd chondromodulin involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2656472|PMID:12714610)		 RGD PMID:12714610, PMID:21873635 MGI:2656472, RGD:13792537 NCBI chr15:61,923,291...61,947,840
Ensembl chr15:61,923,299...61,947,764 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:62,840,360...62,950,240
Ensembl chr 5:64,476,317...64,542,645
Ensembl chr 5:64,476,317...64,542,645 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3046127|PMID:15188432)		 RGD PMID:15188432, PMID:21873635 MGI:3046127, RGD:13792537 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858 		JBrowse link
G Col22a1 collagen type XXII alpha 1 chain involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:113,014,896...113,251,165
Ensembl chr 7:113,015,747...113,228,439 		JBrowse link
G Col24a1 collagen type XXIV alpha 1 chain involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:251,200,686...251,436,254
Ensembl chr 2:251,200,686...251,434,932 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within ISO MGI:3838392 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr11:70,234,248...70,322,966
Ensembl chr11:70,236,888...70,322,690 		JBrowse link
G Hoxa13 homeo box A13 acts_upstream_of_or_within ISO MGI:2152356 (MGI:3797428|PMID:18483557) RGD PMID:18483557 MGI:3797428 NCBI chr 4:82,313,383...82,315,550
Ensembl chr 4:82,228,017...82,229,397 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein acts_upstream_of_or_within ISO MGI:2679939 (MGI:3759000|PMID:17717145) RGD PMID:17717145 MGI:3759000 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:2157527 (MGI:4940123|PMID:21285373) RGD PMID:21285373 MGI:4940123 NCBI chr15:37,690,417...37,786,855
Ensembl chr15:37,691,345...37,784,924 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:14500721)		 Ensembl
RGD		 PMID:14500721 GO_REF:0000107 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Notch4 notch receptor 4 IDA RGD PMID:10964583 RGD:1304484 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:2677448 (MGI:3723364|PMID:17563397) RGD PMID:17563397 MGI:3723364 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 acts_upstream_of_or_within ISO MGI:3620600|MGI:3620601 (MGI:3618677|PMID:16467571) RGD PMID:16467571 MGI:3618677 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982 		JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO (PMID:14500721) RGD PMID:14500721 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162 		JBrowse link
G Tnmd tenomodulin involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2656472|PMID:12714610)		 RGD PMID:12714610, PMID:21873635 MGI:2656472, RGD:13792537 NCBI chr  X:104,684,676...104,700,173
Ensembl chr  X:104,684,676...104,700,173 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5466218|PMID:22282195)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22282195 GO_REF:0000024 GO_REF:0000107 MGI:5466218 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
endothelial tube lumen extension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A involved_in ISO UniProtKB:Q9Y3M8 (PMID:20208559) RGD PMID:20208559 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 involved_in ISO UniProtKB:P61586 (PMID:20208559) RGD PMID:20208559 NCBI chr12:1,023,494...1,418,919
Ensembl chr12:1,023,531...1,195,591 		JBrowse link
endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19592636) RGD PMID:19592636 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335 		JBrowse link
G Bsg basigin (Ok blood group) involved_in ISO
ISS		 (PMID:19837976)
GO_REF:0000024		 RGD
UniProt		 PMID:19837976 GO_REF:0000024 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753 		JBrowse link
G Ccm2 CCM2 scaffold protein involved_in ISO (PMID:19151727) RGD PMID:19151727 NCBI chr14:86,812,728...86,859,408
Ensembl chr14:86,813,082...86,859,406 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO (PMID:19592636) RGD PMID:19592636 NCBI chr20:5,108,692...5,113,675
Ensembl chr20:5,106,890...5,113,112 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
ISS		 (PMID:20123964)
GO_REF:0000024		 RGD
UniProt		 PMID:20123964 GO_REF:0000024 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:24955809 RGD:11352686 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Rhob ras homolog family member B involved_in ISO (PMID:21347332) RGD PMID:21347332 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301 		JBrowse link
establishment of blood-nerve barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2136636 (MGI:2385816|PMID:9734405) RGD PMID:9734405 MGI:2385816 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Cldn1 claudin 1 IMP RGD PMID:22733753 RGD:11341802 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416 		JBrowse link
G Dmd dystrophin acts_upstream_of_or_within ISO MGI:1856328 (MGI:3612931|PMID:12673830) RGD PMID:12673830 MGI:3612931 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259 		JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4437572 (MGI:4437139|PMID:20181608)		 Ensembl
RGD		 PMID:20181608 GO_REF:0000107 MGI:4437139 NCBI chr 2:187,395,104...187,402,076
Ensembl chr 2:187,396,349...187,401,786 		JBrowse link
G Ren renin NOT|acts_upstream_of_or_within ISO MGI:2136642 (MGI:1351364|PMID:10617578) RGD PMID:10617578 MGI:1351364 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151 		JBrowse link
establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn5 claudin 5 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718 		JBrowse link
G Ezr ezrin involved_in ISO UniProtKB:P26038|UniProtKB:P35241 (PMID:23264465) RGD PMID:23264465 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:20826780) RGD PMID:20826780 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO UniProtKB:Q96S97 (PMID:23264465) RGD PMID:23264465 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Marveld2 MARVEL domain containing 2 involved_in ISO (PMID:23073616) RGD PMID:23073616 NCBI chr 2:30,612,746...30,634,308
Ensembl chr 2:30,612,106...30,634,243 		JBrowse link
G Msn moesin involved_in ISO
IEA		 UniProtKB:P15311|UniProtKB:P35241 (PMID:23264465)
GO_REF:0000107		 RGD
Ensembl		 PMID:23264465 GO_REF:0000107 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810 		JBrowse link
G Myadm myeloid-associated differentiation marker involved_in ISO (PMID:23264465) RGD PMID:23264465 NCBI chr 1:64,438,465...64,448,332
Ensembl chr 1:64,438,472...64,446,818 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IDA PMID:20139324 UniProt PMID:20139324 RGD:8553884 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IDA PMID:20139324 UniProt PMID:20139324 RGD:8553884 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO (PMID:7589563) RGD PMID:7589563 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:18586956)
(MGI:5604907|PMID:21907835)
PMID:21873635		 RGD PMID:18586956 PMID:21907835, PMID:21873635 MGI:5604907, RGD:13792537 NCBI chr 3:155,160,474...155,267,002
Ensembl chr 3:155,160,481...155,262,941 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in ISO
ISS		 (PMID:21840392)
GO_REF:0000024		 RGD
UniProt		 PMID:21840392 GO_REF:0000024 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family involved_in ISO
ISS		 (PMID:21840392)
GO_REF:0000024		 RGD
UniProt		 PMID:21840392 GO_REF:0000024 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 involved_in ISO (PMID:21840392) RGD PMID:21840392 NCBI chr 3:8,189,594...8,307,077
Ensembl chr 3:8,192,575...8,304,976 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21840392)		 UniProt
RGD		 PMID:21840392 GO_REF:0000024 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISO
IEA
ISS		 (PMID:21840392)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21840392 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551 		JBrowse link
G Rdx radixin involved_in ISO UniProtKB:P15311|UniProtKB:P26038 (PMID:23264465) RGD PMID:23264465 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612 		JBrowse link
G Robo4 roundabout guidance receptor 4 involved_in ISO (PMID:30455415) RGD PMID:30455415 NCBI chr 8:39,082,693...39,093,344
Ensembl chr 8:39,083,327...39,093,277 		JBrowse link
G Sox18 SRY-box transcription factor 18 involved_in ISO (PMID:18065521) RGD PMID:18065521 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127 		JBrowse link
establishment of endothelial blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B IMP RGD PMID:16850390 RGD:1598561 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Cldn3 claudin 3 involved_in ISO (MGI:6368952|PMID:12734665) RGD PMID:12734665 MGI:6368952 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813 		JBrowse link
G Foxp3 forkhead box P3 IEP RGD PMID:31027862 RGD:38549575 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522 		JBrowse link
establishment of endothelial intestinal barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afdn afadin, adherens junction formation factor involved_in ISO
IEA		 (PMID:23885123)
GO_REF:0000107		 RGD
Ensembl		 PMID:23885123 GO_REF:0000107 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658 		JBrowse link
G Cldn1 claudin 1 IMP RGD PMID:22684624 RGD:11341733 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416 		JBrowse link
G F11r F11 receptor involved_in ISO
IBA		 UniProtKB:Q9Y3L5 (PMID:23885123)
PMID:21873635		 RGD PMID:23885123, PMID:21873635 RGD:13792537 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612 		JBrowse link
G Fasn fatty acid synthase acts_upstream_of_or_within ISO MGI:3765070 (MGI:5630041|PMID:25565205) RGD PMID:25565205 MGI:5630041 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IMP RGD PMID:10201790 RGD:11520782 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Mir874 microRNA 874 acts_upstream_of_or_within ISO (MGI:5551666|PMID:24462679) RGD PMID:24462679 MGI:5551666 NCBI chr17:7,025,014...7,025,089
Ensembl chr17:7,025,014...7,025,089 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2385681 (MGI:5306517|PMID:22155109) RGD PMID:22155109 MGI:5306517 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841 		JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2158734 (MGI:5550154|PMID:24385580)		 Ensembl
RGD		 PMID:24385580 GO_REF:0000107 MGI:5550154 NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939 		JBrowse link
G Rab1a RAB1A, member RAS oncogene family NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr14:104,475,082...104,500,176
Ensembl chr14:104,475,082...104,501,020 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 1:220,483,529...220,491,469
Ensembl chr 1:220,480,834...220,491,469 		JBrowse link
G Rap2b RAP2B, member of RAS oncogene family NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 2:151,685,251...151,685,802
Ensembl chr 2:151,685,251...151,685,802 		JBrowse link
G Rap2c RAP2C, member of RAS oncogene family involved_in ISO UniProtKB:Q9Y624 (PMID:23885123) RGD PMID:23885123 NCBI chr  X:138,224,039...138,237,157
Ensembl chr  X:138,224,040...138,237,157 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157 		JBrowse link
G Rapgef6 Rap guanine nucleotide exchange factor 6 NOT|involved_in ISO (PMID:23885123) RGD PMID:23885123 NCBI chr10:39,875,322...40,039,929
Ensembl chr10:39,875,371...40,039,929 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO
IBA		 (PMID:23885123)
PMID:21873635		 RGD PMID:23885123, PMID:21873635 RGD:13792537 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469 		JBrowse link
G Tjp2 tight junction protein 2 involved_in IBA
ISO		 PMID:21873635
(PMID:23885123)		 RGD PMID:23885123, PMID:21873635 RGD:13792537 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484 		JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,295,892...11,314,535
Ensembl chr 7:11,295,892...11,315,615 		JBrowse link
glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO (PMID:17464107) RGD PMID:17464107 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1857740 (MGI:3619287|PMID:16498405) RGD PMID:16498405 MGI:3619287 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 involved_in ISO (PMID:17464107) RGD PMID:17464107 NCBI chr10:94,850,971...94,913,202 JBrowse link
lymphatic endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B involved_in IEA
ISO		 GO_REF:0000107
(MGI:4436974|PMID:19903896)		 Ensembl
RGD		 PMID:19903896 GO_REF:0000107 MGI:4436974 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746 		JBrowse link
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19903896)
(MGI:4436974|PMID:19903896)		 RGD PMID:19903896 MGI:4436974 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:4436974|PMID:19903896) RGD PMID:19903896 MGI:4436974 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Prox1 prospero homeobox 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:12198161)
MGI:2182767|MGI:3609548 (MGI:3820329|PMID:19056883)		 RGD PMID:12198161 PMID:19056883 MGI:3820329 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO MGI:2178809 (MGI:3828192|PMID:18931657) RGD PMID:18931657 MGI:3828192 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 acts_upstream_of_or_within ISO (MGI:4439415|PMID:20223757) RGD PMID:20223757 MGI:4439415 NCBI chr 5:137,294,544...137,321,116
Ensembl chr 5:137,294,544...137,321,121 		JBrowse link
lymphatic endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 involved_in ISO (PMID:18815287) RGD PMID:18815287 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473 		JBrowse link
G Pdpn podoplanin involved_in ISS
ISO		 GO_REF:0000024
(MGI:4453945|PMID:20110424)		 UniProt
RGD		 PMID:20110424 GO_REF:0000024 MGI:4453945 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:18815287) RGD PMID:18815287 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
metanephric glomerular endothelium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (PMID:9693135) RGD PMID:9693135 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 4:155,653,446...155,679,815
Ensembl chr 4:155,653,718...155,679,793 		JBrowse link
negative regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IMP RGD PMID:20830586 RGD:9686141 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5661129|PMID:25535084)		 Ensembl
RGD		 PMID:25535084 GO_REF:0000107 MGI:5661129 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770 		JBrowse link
G Notch4 notch receptor 4 involved_in ISO (MGI:1934537|PMID:11344305) RGD PMID:11344305 MGI:1934537 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IMP RGD PMID:17450384 RGD:2302022 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:5618205 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845 		JBrowse link
G Xdh xanthine dehydrogenase involved_in IEA
ISO		 GO_REF:0000107
(PMID:18386220)		 Ensembl
RGD		 PMID:18386220 GO_REF:0000107 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23765923)		 Ensembl
RGD		 PMID:23765923 GO_REF:0000107 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914 		JBrowse link
negative regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S1pr3 sphingosine-1-phosphate receptor 3 involved_in ISO (PMID:24851274) RGD PMID:24851274 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:20048167) RGD PMID:20048167 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3847069|PMID:19144989)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19144989 GO_REF:0000024 GO_REF:0000107 MGI:3847069 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
positive regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 involved_in ISO (PMID:24463812) RGD PMID:24463812 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4830635|PMID:20406889)		 Ensembl
RGD		 PMID:20406889 GO_REF:0000107 MGI:4830635 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15033446)		 UniProt
RGD		 PMID:15033446 GO_REF:0000024 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148567 (MGI:3773938|PMID:18231602)		 Ensembl
RGD		 PMID:18231602 GO_REF:0000107 MGI:3773938 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Etv2 ETS variant transcription factor 2 acts_upstream_of_or_within ISO (MGI:4415813|PMID:18462699) RGD PMID:18462699 MGI:4415813 NCBI chr 1:89,091,239...89,094,570
Ensembl chr 1:89,091,239...89,094,530 		JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239 		JBrowse link
G Notch1 notch receptor 1 IMP RGD PMID:19109527 RGD:2325303 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Tmem100 transmembrane protein 100 involved_in ISO (MGI:5432418|PMID:22783020) RGD PMID:22783020 MGI:5432418 NCBI chr10:77,537,340...77,543,710
Ensembl chr10:77,537,340...77,543,192 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 involved_in ISO (PMID:27538588) RGD PMID:27538588 NCBI chr10:75,365,763...75,382,014
Ensembl chr10:75,365,822...75,381,555 		JBrowse link
positive regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:10733500 RGD:2313864 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005 		JBrowse link
G Itgax integrin subunit alpha X involved_in ISO (PMID:30873824) RGD PMID:30873824 NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932 		JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:31759996 RGD:41410819 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301 		JBrowse link
positive regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in IEA
ISO
IBA		 GO_REF:0000107
(MGI:5796260|PMID:25978380)
PMID:21873635
(PMID:25978380)		 Ensembl
RGD		 PMID:25978380, PMID:21873635 GO_REF:0000107 MGI:5796260, RGD:13792537 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496 		JBrowse link
G Akap11 A-kinase anchoring protein 11 IMP RGD PMID:25188285 RGD:14348953 NCBI chr15:60,722,138...60,766,673
Ensembl chr15:60,722,160...60,766,579 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:23288152) RGD PMID:23288152 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365 		JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:23288152) RGD PMID:23288152 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718 		JBrowse link
G F11r F11 receptor involved_in ISO (PMID:26985018) RGD PMID:26985018 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa involved_in ISO
ISS		 (PMID:25651845)
GO_REF:0000024		 RGD
UniProt		 PMID:25651845 GO_REF:0000024 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 involved_in ISO (PMID:24851274) RGD PMID:24851274 NCBI chr 8:21,984,914...21,995,806
Ensembl chr 8:21,984,914...21,995,806 		JBrowse link
pulmonary artery endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17992660)		 UniProt
Ensembl
RGD		 PMID:17992660 GO_REF:0000024 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
regulation of endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apold1 apolipoprotein L domain containing 1 involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:15102925, PMID:21873635 RGD:1303988, RGD:13792537 NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3640069|PMID:16680193)		 UniProt
RGD		 PMID:16680193 GO_REF:0000024 MGI:3640069 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 TAS RGD PMID:12183510 RGD:727411 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO (MGI:5543371|PMID:18772315) RGD PMID:18772315 MGI:5543371 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
regulation of endothelial tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:61,039,072...61,340,687
Ensembl chr 2:61,039,053...61,340,697 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO (PMID:16484616) RGD PMID:16484616 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23469107)		 UniProt
RGD		 PMID:23469107 GO_REF:0000024 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:24023716) RGD PMID:24023716 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755 		JBrowse link
regulation of establishment of endothelial barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta involved_in ISO
IEA		 (PMID:25816133)
GO_REF:0000107		 RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5904576|PMID:27653213)		 Ensembl
RGD		 PMID:27653213 GO_REF:0000107 MGI:5904576 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A NOT|involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr 7:51,404,971...51,515,382
Ensembl chr 7:51,404,919...51,515,373 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA		 UniProtKB:O75116 (PMID:25816133)
GO_REF:0000107		 RGD
Ensembl		 PMID:25816133 GO_REF:0000107 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:25816133) RGD PMID:25816133 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in IEA
ISO		 GO_REF:0000107
(PMID:25816133)		 Ensembl
RGD		 PMID:25816133 GO_REF:0000107 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Vcl vinculin involved_in IEA
ISO		 GO_REF:0000107
(PMID:26923917)		 Ensembl
RGD		 PMID:26923917 GO_REF:0000107 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702 		JBrowse link
G Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 involved_in ISO (MGI:5904576|PMID:27653213) RGD PMID:27653213 MGI:5904576 NCBI chr 5:100,924,621...100,983,412
Ensembl chr 5:100,924,622...100,977,902 		JBrowse link
venous endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      anatomical structure development 6259
        tissue development 2069
          epithelium development 1271
            endothelium development 145
              endocardial endothelium development 0
              endothelial cell differentiation + 125
              glomerular endothelium development + 4
              morphogenesis of an endothelium + 19
paths to the root