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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidic acid biosynthetic process
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Accession:GO:0006654 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
Synonyms:exact_synonym: phosphatidic acid anabolism;   phosphatidic acid biosynthesis;   phosphatidic acid formation;   phosphatidic acid synthesis

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phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in ISO (PMID:18606822) UniProt PMID:18606822 NCBI chrNW_004955420:27,484,500...27,508,360
Ensembl chrNW_004955420:27,482,709...27,508,360 		JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:9212163)
(PMID:9299423)		 BHF-UCL
MGI		 PMID:9212163 PMID:9299423 NCBI chrNW_004955437:633,522...642,659 JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 involved_in ISO (PMID:9212163) BHF-UCL PMID:9212163 NCBI chrNW_004955513:4,142,074...4,145,097
Ensembl chrNW_004955513:4,135,460...4,149,677 		JBrowse link
G Dgka diacylglycerol kinase alpha involved_in ISO (PMID:15544348), (PMID:2175712), (PMID:22627129)
(PMID:23949095)		 UniProt PMID:2175712 PMID:15544348 PMID:22627129 PMID:23949095 NCBI chrNW_004955458:3,517,519...3,544,651
Ensembl chrNW_004955458:3,524,542...3,544,374 		JBrowse link
G Dgkb diacylglycerol kinase beta involved_in ISO PMID:23949095 UniProt PMID:23949095 RGD:30309912 NCBI chrNW_004955410:17,677,375...18,304,409
Ensembl chrNW_004955410:17,676,930...18,243,869 		JBrowse link
G Dgkd diacylglycerol kinase delta involved_in ISO (PMID:17880279), (PMID:23949095) UniProt PMID:17880279 PMID:23949095 NCBI chrNW_004955453:2,740,922...2,802,669
Ensembl chrNW_004955453:2,742,842...2,835,811 		JBrowse link
G Dgke diacylglycerol kinase epsilon involved_in ISO (PMID:15544348), (PMID:19744926), (PMID:22108654) UniProt PMID:15544348 PMID:19744926 PMID:22108654 NCBI chrNW_004955451:5,966,773...5,988,004
Ensembl chrNW_004955451:5,969,070...5,988,004 		JBrowse link
G Dgkg diacylglycerol kinase gamma involved_in ISO (PMID:8034597)
(MGI:6431961|PMID:32033984)		 UniProt PMID:8034597 PMID:32033984 MGI:6431961 NCBI chrNW_004955420:21,296,515...21,481,651
Ensembl chrNW_004955420:21,296,515...21,481,679 		JBrowse link
G Dgkh diacylglycerol kinase eta involved_in ISO (MGI:6253974|PMID:27643686) UniProt PMID:27643686 MGI:6253974 NCBI chrNW_004955518:4,104,700...4,263,657
Ensembl chrNW_004955518:4,113,265...4,208,449 		JBrowse link
G Dgki diacylglycerol kinase iota involved_in ISO PMID:15024004 UniProt PMID:15024004 RGD:1302915 NCBI chrNW_004955494:5,119,419...5,541,058
Ensembl chrNW_004955494:5,264,414...5,539,540 		JBrowse link
G Dgkq diacylglycerol kinase theta involved_in ISO (PMID:22732145), (PMID:23949095), (PMID:9099683)
(PMID:23610160), (PMID:23767959)		 ParkinsonsUK-UCL PMID:9099683 PMID:22732145 PMID:23610160 PMID:23767959 PMID:23949095 NCBI chrNW_004955514:452,548...475,240
Ensembl chrNW_004955514:453,886...464,978 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (PMID:15544348), (PMID:19744926)
(MGI:2672999|PMID:12883552), (MGI:6201900|PMID:27739494)		 UniProt PMID:12883552 PMID:15544348 PMID:19744926 PMID:27739494 MGI:2672999 MGI:6201900 NCBI chrNW_004955422:1,658,237...1,687,000
Ensembl chrNW_004955422:1,657,926...1,695,404 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in ISO PMID:22905194 UniProt PMID:22905194 RGD:30309909 NCBI chrNW_004955431:17,291,890...17,363,611
Ensembl chrNW_004955431:17,291,270...17,363,714 		JBrowse link
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial involved_in ISO (MGI:6228436|PMID:22905194) UniProt PMID:22905194 MGI:6228436 NCBI chrNW_004955470:3,633,076...3,643,635
Ensembl chrNW_004955470:3,632,869...3,643,642 		JBrowse link
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004955487:6,139,188...6,207,316
Ensembl chrNW_004955487:6,138,926...6,210,012 		JBrowse link
G Pld1 phospholipase D1 acts_upstream_of_or_within ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chrNW_004955420:1,697,716...1,892,741
Ensembl chrNW_004955420:1,696,751...1,892,741 		JBrowse link
G Pnpla3 patatin like phospholipase domain containing 3 involved_in ISO (PMID:22560221)
(MGI:5426312|PMID:22560221)		 BHF-UCL PMID:22560221 MGI:5426312 NCBI chrNW_004955413:28,879,646...28,896,224
Ensembl chrNW_004955413:28,879,748...28,893,938 		JBrowse link
G Sh3glb1 SH3 domain containing GRB2 like, endophilin B1 acts_upstream_of_or_within ISO (PMID:12456676) MGI PMID:12456676 NCBI chrNW_004955423:7,393,186...7,414,199
Ensembl chrNW_004955423:7,393,186...7,423,903 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO (PMID:19523918) UniProt PMID:19523918 NCBI chrNW_004955524:803,793...821,920
Ensembl chrNW_004955524:805,014...821,838 		JBrowse link
positive regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (PMID:23767959) ParkinsonsUK-UCL PMID:23767959 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751 		JBrowse link
regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:27806294) MGI PMID:27806294 NCBI chrNW_004955599:505,725...514,225
Ensembl chrNW_004955599:507,501...514,151 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular metabolic process 6295
        cellular biosynthetic process 5017
          glycerolipid biosynthetic process 174
            glycerophospholipid biosynthetic process 130
              phosphatidic acid biosynthetic process 21
                negative regulation of phosphatidic acid biosynthetic process 0
                positive regulation of phosphatidic acid biosynthetic process 1
                regulation of phosphatidic acid biosynthetic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      cellular metabolic process 6295
        phosphorus metabolic process 1494
          phosphate-containing compound metabolic process 1474
            phospholipid metabolic process 285
              glycerophospholipid metabolic process 225
                phosphatidic acid metabolic process 24
                  phosphatidic acid biosynthetic process 21
                    negative regulation of phosphatidic acid biosynthetic process 0
                    positive regulation of phosphatidic acid biosynthetic process 1
                    regulation of phosphatidic acid biosynthetic process + 2
paths to the root