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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cell-matrix adhesion
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Accession:GO:0001953 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
Synonyms:exact_synonym: down-regulation of cell-matrix adhesion;   downregulation of cell-matrix adhesion
 narrow_synonym: inhibition of cell-matrix adhesion


show annotations for term's descendants           Sort by:
negative regulation of cell-matrix adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER2 alkaline ceramidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,398,961...130,410,860
Ensembl chr 1:134,008,959...134,020,467 		JBrowse link
G AJAP1 adherens junctions associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:3,340,904...3,482,242
Ensembl chr 1:4,505,143...4,590,779 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15860730) Ensembl
MGI		 PMID:15860730 GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,967,329...34,374,385
Ensembl chr  X:41,659,295...42,066,570 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:10205165) BHF-UCL PMID:10205165 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO RGD PMID:12837632 RGD:1299196 NCBI chr 8:116,248,587...116,364,966
Ensembl chr 8:118,998,530...119,114,273 		JBrowse link
G HOXA7 homeobox A7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:27,799,317...27,802,492
Ensembl chr 7:27,396,898...27,402,142 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:10,582,234...10,618,507
Ensembl chr20:10,582,094...10,618,383 		JBrowse link
G MUC4 mucin 4, cell surface associated ISO RGD PMID:9407114 RGD:2303753 NCBI chr 3:193,050,895...193,114,931 JBrowse link
G MYOC myocilin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628 		JBrowse link
G NEXMIF neurite extension and migration factor involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:24071057 GO_REF:0000118 RGD:13442493 NCBI chr  X:63,985,226...64,177,750
Ensembl chr  X:74,107,799...74,114,635 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17053831) Ensembl
MGI		 PMID:17053831 GO_REF:0000107 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17053831) Ensembl
MGI		 PMID:17053831 GO_REF:0000107 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960 		JBrowse link
G PLET1 placenta expressed transcript 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:107,126,523...107,141,857
Ensembl chr11:110,971,824...110,984,838 		JBrowse link
G POSTN periostin ISO RGD PMID:15381649 RGD:10040999 NCBI chr13:18,779,297...18,815,207
Ensembl chr13:37,368,030...37,407,212 		JBrowse link
G RASA1 RAS p21 protein activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:27,980,907...28,104,368
Ensembl chr 5:28,115,159...28,240,321 		JBrowse link
G SEMA3E semaphorin 3E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,329,049...75,612,946
Ensembl chr 7:88,995,049...89,274,241 		JBrowse link
G THBS1 thrombospondin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16150726) MGI
Ensembl		 PMID:16150726 GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
negative regulation of endothelial cell-matrix adhesion via fibronectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,809,644...97,822,063
Ensembl chr11:101,294,475...101,306,762 		JBrowse link
negative regulation of focal adhesion assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691 		JBrowse link
G APOD apolipoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:192,852,887...192,868,233
Ensembl chr 3:203,152,476...203,168,060 		JBrowse link
G ARHGAP6 Rho GTPase activating protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:3,767,259...4,291,738
Ensembl chr  X:11,058,207...11,582,115 		JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) UniProt PMID:24859005 NCBI chr 3:33,418,300...33,640,185
Ensembl chr 3:33,721,153...33,938,560 		JBrowse link
G CORO1C coronin 1C involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,220,755...106,306,098
Ensembl chr12:109,617,093...109,674,368 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G DMTN dematin actin binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:21,293,759...21,327,600
Ensembl chr 8:18,251,886...18,266,229 		JBrowse link
G DUSP22 dual specificity phosphatase 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:107,145...180,777
Ensembl chr 6:242,121...301,248 		JBrowse link
G FAM107A family with sequence similarity 107 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:58,494,342...58,557,712
Ensembl chr 3:59,903,602...59,967,013 		JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:9,396,553...9,413,408
Ensembl chr2A:9,556,857...9,577,155 		JBrowse link
G LRP1 LDL receptor related protein 1 ISO RGD PMID:20197276 RGD:13800550 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:15044209 RGD:1582604 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G PHLDB2 pleckstrin homology like domain family B member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:108,878,798...109,120,501
Ensembl chr 3:115,745,634...116,044,586 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:9616126) UniProt PMID:9616126 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G RCC2 regulator of chromosome condensation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:16,353,770...16,386,810
Ensembl chr 1:17,409,432...17,432,031 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO PMID:21440892 BHF-UCL PMID:21440892 RGD:7248703 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
negative regulation of smooth muscle cell-matrix adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOD apolipoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:192,852,887...192,868,233
Ensembl chr 3:203,152,476...203,168,060 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16442
    cellular process 15499
      negative regulation of cellular process 5192
        negative regulation of cell adhesion 311
          negative regulation of cell-substrate adhesion 63
            negative regulation of cell-matrix adhesion 37
              negative regulation of endothelial cell-matrix adhesion via fibronectin 1
              negative regulation of focal adhesion assembly 16
              negative regulation of smooth muscle cell-matrix adhesion 2
Path 2
Term Annotations click to browse term
  biological_process 16442
    biological regulation 11463
      regulation of biological process 11110
        regulation of cellular process 10606
          regulation of cell adhesion 793
            negative regulation of cell adhesion 311
              negative regulation of cell-substrate adhesion 63
                negative regulation of cell-matrix adhesion 37
                  negative regulation of endothelial cell-matrix adhesion via fibronectin 1
                  negative regulation of focal adhesion assembly 16
                  negative regulation of smooth muscle cell-matrix adhesion 2
paths to the root