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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cell-substrate adhesion
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Accession:GO:0010812 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.


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negative regulation of cell-substrate adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt2 angiopoietin 2 acts_upstream_of_or_within ISO (PMID:9846489) RGD PMID:9846489 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Col1a1 collagen type I alpha 1 chain acts_upstream_of_or_within ISO (PMID:17018525) RGD PMID:17018525 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Coro2b coronin 2B acts_upstream_of_or_within ISO (PMID:29162887) RGD PMID:29162887 NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302 		JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) RGD PMID:18505823 MGI:3803395 NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Fzd4 frizzled class receptor 4 involved_in ISO (PMID:18156211)
(MGI:3772546|PMID:18156211)		 RGD PMID:18156211 MGI:3772546 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:18156211)
(MGI:3772546|PMID:18156211)		 RGD PMID:18156211 MGI:3772546 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO (PMID:21750175) RGD PMID:21750175 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Lgals1 galectin 1 IDA RGD PMID:1955484 RGD:2316546 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lrp1 LDL receptor related protein 1 IMP RGD PMID:20197276 RGD:13800550 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Men1 menin 1 IMP RGD PMID:15054094 RGD:1304318 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir183 microRNA 183 acts_upstream_of ISO (PMID:19940135) RGD PMID:19940135 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir503 microRNA 503 involved_in ISO (PMID:21220732) RGD PMID:21220732 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Plg plasminogen involved_in ISO (PMID:14699093) RGD PMID:14699093 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 IMP RGD PMID:10484424 RGD:401965470 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IDA RGD PMID:12821372 RGD:9589826 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (MGI:5927441|PMID:18981818) RGD PMID:18981818 MGI:5927441 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 involved_in ISO (PMID:12853036) RGD PMID:12853036 NCBI chr17:6,741,504...7,221,685
Ensembl chr17:6,742,273...7,224,935 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
negative regulation of cell-matrix adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:18945876) RGD PMID:18945876 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Adam15 ADAM metallopeptidase domain 15 involved_in ISO (PMID:22505472) RGD PMID:22505472 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113 		JBrowse link
G Ajap1 adherens junctions associated protein 1 involved_in ISO (PMID:16410724) RGD PMID:16410724 NCBI chr 5:163,907,846...164,021,004
Ensembl chr 5:163,907,847...164,020,317 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158438 (PMID:15860730) RGD PMID:15860730 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase involved_in ISO (PMID:18664494) RGD PMID:18664494 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:10205165) RGD PMID:10205165 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IDA RGD PMID:12837632 RGD:1299196 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Hoxa7 homeobox A7 involved_in ISO
IEA		 (PMID:14704364)
GO_REF:0000107		 RGD
Ensembl		 PMID:14704364 GO_REF:0000107 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in ISO
IEA		 (PMID:11549580)
GO_REF:0000107		 RGD
Ensembl		 PMID:11549580 GO_REF:0000107 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Mir192 microRNA 192 involved_in ISO (PMID:26506238) RGD PMID:26506238 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
G Muc4 mucin 4, cell surface associated IDA RGD PMID:9407114 RGD:2303753 NCBI chr11:68,008,245...68,053,242 JBrowse link
G Myoc myocilin involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17984096)		 Ensembl
UniProt
RGD		 PMID:17984096 GO_REF:0000024 GO_REF:0000107 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Nexmif neurite extension and migration factor involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:24071057 GO_REF:0000033, RGD:13442493 NCBI chr  X:69,088,076...69,219,253
Ensembl chr  X:69,088,076...69,112,930 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1339753|MGI:97583 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97306 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plet1 placenta expressed transcript 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:4453442|PMID:20130590)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:20130590 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:4453442 NCBI chr 8:50,842,242...50,853,666
Ensembl chr 8:50,841,854...50,853,659 		JBrowse link
G Postn periostin IDA RGD PMID:15381649 RGD:10040999 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Rasa1 RAS p21 protein activator 1 involved_in ISO
ISS
IEA		 (PMID:8344248)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:8344248 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Sema3e semaphorin 3E involved_in ISO (MGI:4819325|PMID:20385769) RGD PMID:20385769 MGI:4819325 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
G Thbs1 thrombospondin 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:17416590)
(PMID:16150726)		 RGD PMID:16150726 PMID:17416590 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
negative regulation of endothelial cell-matrix adhesion via fibronectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir92a1 microRNA 92a-1 involved_in ISO (PMID:19460962) RGD PMID:19460962 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
G Mir92a2 microRNA 92a-2 involved_in ISO (PMID:19460962) RGD PMID:19460962 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO
IEA		 (PMID:29101312)
GO_REF:0000107		 RGD
Ensembl		 PMID:29101312 GO_REF:0000107 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
negative regulation of focal adhesion assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:12453878) RGD PMID:12453878 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Apod apolipoprotein D involved_in ISS
ISO		 GO_REF:0000024
(PMID:21705670)		 UniProt
RGD		 PMID:21705670 GO_REF:0000024 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Arhgap6 Rho GTPase activating protein 6 involved_in ISO (PMID:10699171) RGD PMID:10699171 NCBI chr  X:24,953,464...25,490,003
Ensembl chr  X:24,953,464...25,488,663 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Coro1c coronin 1C involved_in ISO (PMID:19913511) RGD PMID:19913511 NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in ISO
IEA		 (PMID:19158340)
GO_REF:0000107		 RGD
Ensembl		 PMID:19158340 GO_REF:0000107 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) RGD PMID:18505823 MGI:3803395 NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Dusp22 dual specificity phosphatase 22 involved_in ISO (PMID:20018849) RGD PMID:20018849 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Fam107a family with sequence similarity 107, member A involved_in ISO
IEA
ISS		 (PMID:20543869)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20543869 GO_REF:0000024 GO_REF:0000107 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO
IBA		 (PMID:12473654)
GO_REF:0000033
(MGI:5486544|PMID:18227284)		 RGD
GO_Central		 PMID:12473654 PMID:18227284 GO_REF:0000033 MGI:5486544 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Lrp1 LDL receptor related protein 1 IMP RGD PMID:20197276 RGD:13800550 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Mmp14 matrix metallopeptidase 14 IDA RGD PMID:15044209 RGD:1582604 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:9616126) RGD PMID:9616126 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO (MGI:5551375|PMID:19738201) RGD PMID:19738201 MGI:5551375 NCBI chr 5:152,994,406...153,017,223
Ensembl chr 5:152,993,665...153,017,205 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP PMID:21440892 BHF-UCL PMID:21440892 RGD:7248703 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
negative regulation of smooth muscle cell-matrix adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apod apolipoprotein D involved_in ISS
ISO		 GO_REF:0000024
(PMID:21705670)		 UniProt
RGD		 PMID:21705670 GO_REF:0000024 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:8837777)		 Ensembl
RGD		 PMID:8837777 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
negative regulation of substrate adhesion-dependent cell spreading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 involved_in ISO
IEA		 (PMID:25918384)
GO_REF:0000107		 RGD
Ensembl		 PMID:25918384 GO_REF:0000107 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein acts_upstream_of_or_within ISO (PMID:22689987)
MGI:5439984 (PMID:22689987)		 RGD PMID:22689987 NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member IMP RGD PMID:15817476 RGD:7488898 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Coro1c coronin 1C involved_in ISO (PMID:19913511) RGD PMID:19913511 NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (MGI:3803395|PMID:18505823) RGD PMID:18505823 MGI:3803395 NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Efna5 ephrin A5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23242526)
GO_REF:0000107		 RGD
Ensembl		 PMID:23242526 GO_REF:0000107 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413 		JBrowse link
G Fbln1 fibulin 1 involved_in ISO (PMID:11792823) RGD PMID:11792823 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO
IBA		 (PMID:11807099)
GO_REF:0000033
(MGI:5486544|PMID:18227284)		 RGD
GO_Central		 PMID:11807099 PMID:18227284 GO_REF:0000033 MGI:5486544 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:19171758) RGD PMID:19171758 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300 		JBrowse link
G Postn periostin IDA RGD PMID:15381649 RGD:10040999 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO (MGI:5551375|PMID:19738201) RGD PMID:19738201 MGI:5551375 NCBI chr 5:152,994,406...153,017,223
Ensembl chr 5:152,993,665...153,017,205 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 involved_in ISO (PMID:15584898) RGD PMID:15584898 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5315060|PMID:22194864)		 Ensembl
UniProt
RGD		 PMID:22194864 GO_REF:0000024 GO_REF:0000107 MGI:5315060 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
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