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ONTOLOGY REPORT - ANNOTATIONS


Term:formation of extrachromosomal circular DNA
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Accession:GO:0001325 term browser browse the term
Definition:Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.
Synonyms:exact_synonym: assembly of extrachromosomal circular DNA


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negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IBA
(PMID:25620558)
(MGI:5522574|PMID:24115439), (MGI:5645200|PMID:22579284)
PMID:21873635
RGD PMID:22579284 PMID:24115439 PMID:25620558, PMID:21873635 MGI:5522574 MGI:5645200, RGD:13792537 NCBI chr 3:176,818,012...176,856,531
Ensembl chr 3:176,818,437...176,856,531
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207) RGD PMID:15507207 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) RGD PMID:19581589 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 1:198,114,514...198,120,061
Ensembl chr 1:198,112,245...198,120,061
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr10:11,787,756...11,808,326
Ensembl chr10:11,786,121...11,807,928
JBrowse link
t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Nbn nibrin involved_in ISO
IEA
(PMID:27918544)
GO_REF:0000107
RGD
Ensembl
PMID:27918544 GO_REF:0000107 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755)
(MGI:5645200|PMID:22579284)
RGD PMID:22579284 PMID:24012755 MGI:5645200 NCBI chr 1:198,114,514...198,120,061
Ensembl chr 1:198,112,245...198,120,061
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755)
(MGI:5645200|PMID:22579284)
RGD PMID:22579284 PMID:24012755 MGI:5645200 NCBI chr10:11,787,756...11,808,326
Ensembl chr10:11,786,121...11,807,928
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in IBA
ISO
PMID:21873635
(PMID:21903669)
RGD PMID:21903669, PMID:21873635 RGD:13792537 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19611
    metabolic process 11877
      cellular metabolic process 10830
        cellular macromolecule metabolic process 8308
          DNA metabolic process 887
            formation of extrachromosomal circular DNA 8
              t-circle formation + 8
Path 2
Term Annotations click to browse term
  biological_process 19611
    metabolic process 11877
      nitrogen compound metabolic process 10093
        cellular nitrogen compound metabolic process 6614
          nucleobase-containing compound metabolic process 5410
            nucleic acid metabolic process 4921
              DNA metabolic process 887
                formation of extrachromosomal circular DNA 8
                  t-circle formation + 8
paths to the root