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ONTOLOGY REPORT - ANNOTATIONS

Term:formation of extrachromosomal circular DNA
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Accession:GO:0001325 term browser browse the term
Definition:Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.
Synonyms:exact_synonym: assembly of extrachromosomal circular DNA


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negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IBA		 (PMID:25620558)
GO_REF:0000033
(PMID:22579284), (PMID:24115439)		 RGD
GO_Central		 PMID:22579284 PMID:24115439 PMID:25620558 GO_REF:0000033 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207) RGD PMID:15507207 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) RGD PMID:19581589 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
positive regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:22579284) RGD PMID:22579284 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Nbn nibrin involved_in ISO
IEA		 (PMID:27918544)
GO_REF:0000107		 RGD
Ensembl		 PMID:27918544 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755)
(PMID:22579284)		 RGD PMID:22579284 PMID:24012755 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755)
(PMID:22579284)		 RGD PMID:22579284 PMID:24012755 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO
IBA		 (PMID:21903669)
GO_REF:0000033		 RGD
GO_Central		 PMID:21903669 GO_REF:0000033 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    cellular process 19130
      cellular component organization or biogenesis 7164
        cellular component organization 6910
          cellular component assembly 3195
            formation of extrachromosomal circular DNA 8
              t-circle formation + 8
Path 2
Term Annotations click to browse term
  biological_process 20052
    cellular process 19130
      metabolic process 11925
        primary metabolic process 10561
          nucleobase-containing compound metabolic process 5791
            nucleic acid metabolic process 5183
              DNA metabolic process 966
                formation of extrachromosomal circular DNA 8
                  t-circle formation + 8
paths to the root