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ONTOLOGY REPORT - ANNOTATIONS

Term:double-strand break repair via break-induced replication
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Accession:GO:0000727 term browser browse the term
Definition:The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.


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double-strand break repair via break-induced replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC45 cell division cycle 45 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612 		JBrowse link
G CDC7 cell division cycle 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:91,500,851...91,525,764
Ensembl chr 1:91,500,851...91,525,764 		JBrowse link
G GINS2 GINS complex subunit 2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073 		JBrowse link
G GINS4 GINS complex subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:41,529,261...41,545,030
Ensembl chr 8:41,529,218...41,545,030 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,410...127,622,436 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940 		JBrowse link
G MCMDC2 minichromosome maintenance domain containing 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:66,870,771...66,926,382
Ensembl chr 8:66,870,749...66,922,048 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit involved_in IEA
IBA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr11:65,859,674...65,867,653
Ensembl chr11:65,857,126...65,867,653 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19670
    cellular process 18301
      cellular response to stimulus 8383
        cellular response to stress 2150
          DNA damage response 964
            DNA repair 647
              double-strand break repair 328
                double-strand break repair via homologous recombination 190
                  double-strand break repair via break-induced replication 12
                    negative regulation of double-strand break repair via break-induced replication 0
                    regulation of double-strand break repair via break-induced replication + 0
Path 2
Term Annotations click to browse term
  biological_process 19670
    metabolic process 12471
      organic substance metabolic process 11974
        organic cyclic compound metabolic process 7070
          nucleobase-containing compound metabolic process 6539
            nucleic acid metabolic process 5935
              DNA metabolic process 1074
                DNA repair 647
                  recombinational repair 196
                    double-strand break repair via homologous recombination 190
                      double-strand break repair via break-induced replication 12
                        negative regulation of double-strand break repair via break-induced replication 0
                        regulation of double-strand break repair via break-induced replication + 0
paths to the root